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StrokeSTARNCT04994756

Stroke Thrombectomy and Aneurysm Registry

An observational study of Stroke and Thromboses, Intracranial, run by Medical University of South Carolina at 63 sites in 9 countries.

Recruiting

Looking for participants now. Contact the study team or a site below to ask about taking part.

Sites and contacts
Official record
Search all trials

Trial summary

This international multi-center registry is used to collect existing information and outcomes for patients undergoing an operation for treatment of injuries to the brain including the blockage of blood flow to an area of the brain, an abnormal ballooning of an artery, abnormal tangling of blood vessels, abnormal… Read more about this study

Who is it for?
Ages 1 year to 120 years
Conditions the study is for
Stroke, Thromboses, Intracranial, Aneurysm, Brain
What is being tested?
Stroke/Thrombectomy/Aneurysm-specific surgical procedures
Type of treatment
Surgery or procedure
How many people
40,000 participants
Where
63 sitesin 9 countries
Study dates
17 Sep 2019to 1 Jan 2055
How long will I take part?
90 Days
Phase
Observational
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 1 year to 120 years
  • All sexes
  • No healthy volunteers
  • Child, Adult, Older adult

Study population: Any patients between 1 and 120 years of age, undergoing surgical intervention for central nervous system vascular lesions.

Who may be able to join

  • Undergoing surgical intervention for central nervous system vascular lesion
  • Between 1 and 120 years of age

Who cannot join

  • No exclusion criteria

Trial locations and contacts

63 sites in 9 countries. Contact the study team or a site near you to ask about taking part.

Alejandro M Spiotta, MD contact

843-792-9226

spiotta@musc.edu

Meredith Robinson, MS contact

843-792-3164

robme@musc.edu

63 sites in 9 countries

United States54 sites, 54 recruiting

  • Albany Medical Center

    Albany, New York, 12208

    Alexandra Paul, MD, PaulA1@amc.edu

    Alexandra Paul, MD

    Recruiting

  • University of Michigan

    Ann Arbor, Michigan, 48109

    Aditya Pandey, MD, adityap@med.umich.edu

    Aditya Pandey, MD

    Recruiting

  • Piedmont Healthcare

    Atlanta, Georgia, 30318

    Michael Stiefel, MD, michael.stiefel@piedmont.org

    Michael Stiefel, MD

    Recruiting

  • Emory University

    Atlanta, Georgia, 30322

    Jonathan Grossberg, MD, jonathan.a.grossberg@emory.edu

    Recruiting

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35233

    Elizabeth Liptrap, MD, (205) 934-7170, elizabethle@uabmc.edu

    Elizabeth Liptrap, MD

    Recruiting

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215

    Christopher Ogilvy, MD, 617-632-7246, cogilvy@bidmc.harvard.edu

    Ajith Thomas, MD, 617-632-7246, athomas6@bidmc.harvard.edu

    Recruiting

  • Medical University of South Carolina

    Charleston, South Carolina, 29425

    Alejandro M Spiotta, MD, 843-792-9226, spiotta@musc.edu

    Meredith M Robinson, MS, 843-792-3164, robme@musc.edu

    Recruiting

  • University of Virginia

    Charlottesville, Virginia, 22904

    Ryan Kellogg, MD, 434.924.7558, rtk4u@uvahealth.org

    Judith Beenhakker, 434.924.7558, jgb3p@hscmailmcc.virginia.edu

    Recruiting

  • Rush University

    Chicago, Illinois, 60612

    Richard Crowley, MD, (312) 942-7100, Webster_Crowley@rush.edu

    Michael Chen, MD, (312) 942-7100, Michael_Chen@rush.edu

    Recruiting

  • University of Chicago

    Chicago, Illinois, 60637

    Tareq Kass-hout, MD, tkasshout@neurology.bsd.uchicago.edu

    Tareq Kass-hout, MD

    Recruiting

  • University of Illinois

    Chicago, Illinois, 60637

    Ali Alaraj, MD, alaraj@uic.edu

    Ali Alaraj, MD

    Recruiting

  • Nuvance Health

    Danbury, Connecticut, 06810

    Jonathon Lebovitz, MD, 203-792-2003, Jonathon.Lebovitz@nuvancehealth.org

    Jonathon Lebovitz, MD

    Recruiting

  • Endeavor Health

    Evanston, Illinois, 60201

    Shakeel Chowdhry, MD, schowdhry@northshore.org

    Shakeel Chowdhry, MD

    Recruiting

  • University of Florida

    Gainesville, Florida, 32611

    Nohra Chalouhi, MD, 352-273-9000, nc@neurosurgery.ufl.edu

    Brian Hoh, MD, 352-273-9000, Brian.hoh@neurosurgery.ufl.edu

    Recruiting

  • The University of Texas Medical Branch at Galveston

    Galveston, Texas, 77555

    Peter Kan, MD, ptkan@utmb.edu

    Peter Kan, MD

    Recruiting

  • The Feinstein Institutes for Medical Research

    Great Neck, New York, 11021

    Timothy White, MD, (516) 550-2100, twhite7@northwell.edu

    Timothy White, MD

    Recruiting

  • Valley Baptist Medical Center

    Harlingen, Texas, 78550

    Ameer Hassan, DO, 956-804-5851, ameer.hassan@tenethealth.com

    Ameer Hassan, DO

    Recruiting

  • The Queens Health Center

    Honolulu, Hawaii, 96813

    Sam Tsappidi, MD, 808-691-2727, STsappidi@Queens.Org

    Sam Tsappidi, MD

    Recruiting

  • Baylor College of Medicine

    Houston, Texas, 77030

    Omar Tanweer, MD, 713-798-5421, omar.tanweer@bcm.edu

    Melissa Fink, 713-798-5421, melyssa.fink@bcm.edu

    Recruiting

  • Indiana University

    Indianapolis, Indiana, 46202

    Kaustubh Limaye, MD, 317-948-5450, klimaye@iu.edu

    Kaustubh Limaye, MD

    Recruiting

  • University of Iowa

    Iowa City, Iowa, 52242

    Amir Shaban, MD, 319-467-5463, amir-shaban@uiowa.edu

    Edgar Samaniego, MD,MS, 319-467-5463, edgar-samaniego@uiowa.edu

    Recruiting

  • Mayo Clinic in Florida

    Jacksonville, Florida, 32224

    Christopher Fox, MD, fox.chris@mayo.edu

    Christopher Fox, MD

    Recruiting

  • University of Kansas Medical Center

    Kansas City, Kansas, 66103

    Jeremy Peterson, MD, jpeterson6@kumc.edu

    Jeremy Peterson, MD

    Recruiting

  • HCA Houston Healthcare Kingwood

    Kingwood, Texas, 77339

    Mohamad Ezzeldin, MD

    Mohamad Ezzeldin, MD

    Recruiting

  • Loma Linda University

    Loma Linda, California, 92350

    Justin Dye, MD, jdye@llu.edu

    Justin Dye, MD

    Recruiting

  • University of Louisville

    Louisville, Kentucky, 40292

    Issac Abecassis, MD, Isaac.Abecassis@uoflhealth.org

    Issac Abecassis, MD

    Recruiting

  • University of Tennessee Health Science Center

    Memphis, Tennessee, 38163

    Adam Arthur, MD, 901.448.6375, aarthur@semmes-murphey.com

    Nitin Goyal, MD, 901.448.6375, ngoyal@uthsc.edu

    Recruiting

  • University of Miami Health System

    Miami, Florida, 33136

    Robert Starke, MD, MSC, 305-243-6946, rstarke@med.miami.edu

    Dileep Yavagal, MD, dyavagal@med.miami.edu

    Recruiting

  • West Virginia University

    Morgantown, West Virginia, 26506

    Ansaar Rai, MD, 304-598-4051, raia@wvumedicine.org

    Jennifer Domico, 304-598-4051, jennifer.domico@wvumedicine.org

    Recruiting

  • Rutgers University

    New Brunswick, New Jersey, 08901

    Gaurav Gupta, MD

    Gaurav Gupta, MD

    Recruiting

  • Yale University

    New Haven, Connecticut, 06520

    Charles Matouk, MD, charles.matouk@yale.edu

    Charles Matouk, MD

    Recruiting

  • Tulane University

    New Orleans, Louisiana, 70112

    Kendrick Johnson, MD, 504-988-5000, kjohnson28@tulane.edu

    Kendrick Johnson, MD

    Recruiting

  • University of Oklahoma

    Oklahoma City, Oklahoma, 73019

    Andrew Bauer, MD, Andrew-Bauer@ouhsc.edu

    Andrew Bauer, MD

    Recruiting

  • Global Neurosciences Institute

    Pennington, New Jersey, 08534

    Mandy Binning, MD, mbinning@gnineuro.org

    Mandy Binning, MD

    Recruiting

  • Thomas Jefferson University

    Philadelphia, Pennsylvania, 19107

    Pascal Jabbour, MD, 215-955-7000, pascal.jabbour@jefferson.edu

    Stavropoula Tjoumakaris, MD, 215-955-7000, Stavropoula.Tjoumakaris@jefferson.edu

    Recruiting

  • Alleghany Hospital

    Pittsburgh, Pennsylvania, 15212

    Russell Cerejo, MD, russell.cerejo@ahn.org

    Russell Cerejo, MD

    Recruiting

  • Texas Stroke Institute

    Plano, Texas, 75075

    Albert Yoo, MD

    Albert Yoo, MD

    Recruiting

  • Portsmouth Regional Hospital

    Portsmouth, New Hampshire, 03801

    Angali Dose-kolanu, MD, anjali.dosekolanu@hcahealthcare.com

    Angali Dose-kolanu, MD

    Recruiting

  • University of North Carolina

    Raleigh, North Carolina, 27607

    Omar Kass-hout, MD

    Omar Kass-hout, MD

    Recruiting

  • Mayo Clinic

    Rochester, Minnesota, 55905

    Waleed Brinjikji, MD, brinjikji.waleed@mayo.edu

    Waleed Brinjikji, MD

    Recruiting

  • University of Utah

    Salt Lake City, Utah, 84112

    Ramesh Grandhi, MD, MS, ramesh.grandhi@hsc.utah.edu

    Ramesh Grandhi, MD, MS

    Recruiting

  • University of Texas Health Science Center at San Antonio

    San Antonio, Texas, 78229

    Justin Mascitelli, MD, mascitelli@uthscsa.edu

    Justin Mascitelli, MD

    Recruiting

  • Cottage Health Research Institute

    Santa Barbara, California, 93105

    Brian Walcott, MD, 805-569-7820, bwalcott@sbch.org

    Brian Walcott, MD

    Recruiting

  • University of Washington

    Seattle, Washington, 98195

    Michael Levitt, MD, 206-221-8967, mlevitt@neurosurgery.washington.edu

    Louis Kim, MD, 206-221-8967, sanslab@uw.edu

    Recruiting

  • Louisiana State University Health Shreveport

    Shreveport, Louisiana, 71103

    Hugo Cuellar, MD, PhD, hcuell@lsuhsc.edu

    Hugo Cuellar, MD, PhD

    Recruiting

  • Washington University in St. Louis

    St Louis, Missouri, 63110

    Joshua Osbun, MD, 314-362-3570, josbun@wustl.edu

    Brigette Vaughn, 314-362-3570, b.vaughn@wustl.edu

    Recruiting

  • Stony Brook University

    Stony Brook, New York, 11794

    David Fiorella, MD, PhD, david.fiorella@stonybrookmedicine.edu

    David Fiorella, MD, PhD

    Recruiting

  • University of South Florida

    Tampa, Florida, 33620

    Maxim Mokin, MD, PhD

    Maxim Mokin, MD, PhD

    Recruiting

  • Montefiore Medical Center

    The Bronx, New York, 10467

    David Altschul, MD, daltschu@montefiore.org

    David Altschul, MD

    Recruiting

  • Mercy Health

    Toledo, Ohio, 43608

    Osama Zaidat, MD

    Osama Zaidat, MD

    Recruiting

  • Geisinger Medical Group

    Wilkes-Barre, Pennsylvania, 18702

    Clemens Schirmer, MD, PhD, cmschirmer@geisinger.edu

    Clemens Schirmer, MD, PhD

    Recruiting

  • Wake Forest Baptist Health

    Winston-Salem, North Carolina, 27157

    Stacey Wolfe, MD, 336-716-4081, sqwolfe@wakehealth.edu

    Kyle Fargen, MD, 336-716-4081, kfargen@wakehealth.edu

    Recruiting

  • University of Michigan Health-West

    Wyoming, Michigan, 49519

    Fazeel Siddiqui, MD, FAHA, Fazeel.Siddiqui@umhwest.org

    Fazeel Siddiqui, MD, FAHA

    Recruiting

  • WellSpan York Hospital

    York, Pennsylvania, 17403

    Michael Casey, DO

    Michael Casey, DO

    Recruiting

Other trials in United States

Germany2 sites, 2 recruiting

  • Universitätsmedizin Göttingen

    Göttingen

    Ilko Maier, MD, ilko.maier@med.uni-goettingen.de

    Marielle Ernst, MD, mariellesophie.ernst@med.uni-goettingen.de

    Recruiting

  • University Clinic for Neuroradiology

    Magdeburg

    Daniel Behme, MD, +49 391 67-21608, daniel.behme@med.ovgu.de

    Daniel Behme, MD

    Recruiting

Other trials in Germany

Canada1 site, 1 recruiting

  • University of Saskatchewan

    Saskatoon

    Uzair Ahmed, MD, uzair.ahmed@usask.ca

    Uzair Ahmed, MD

    Recruiting

Other trials in Canada

Japan1 site, 1 recruiting

  • Hyogo College of Medicine

    Hyōgo

    Shinichi Yoshimura, MD, PHD, s-yoshi@hyo-med.ac.jp

    Recruiting

Other trials in Japan

Portugal1 site, 1 recruiting

  • Centro Hospitalar Universitário de Lisboa Central

    Lisbon

    Isabel Fragata, MD,PHD

    Isabel Fragata, MD,PHD

    Recruiting

Other trials in Portugal

South Korea1 site, 1 recruiting

  • Chonnam National University Hospital

    Gwangju

    Joon-Tae Kim, MD, alldelight2@chonnam.ac.kr

    Min-Ji Choi, MD, minji2448@naver.com

    Recruiting

Other trials in South Korea

Spain1 site, 1 recruiting

  • Hospital Universitario La Paz

    Madrid

    Pedro Navia, MD, PhD

    Pedro Navia, MD, PhD

    Recruiting

Other trials in Spain

Switzerland1 site, 1 recruiting

  • Universitätsspital Basel

    Basel

    Alex Brehm, MD, alex.brehm@usb.ch

    Marios-Nikos Psychogios, MD

    Recruiting

Other trials in Switzerland

Uruguay1 site, 1 recruiting

  • Médica Uruguaya

    Montevideo

    Roberta Crosa, MD, rocrossa@gmail.com

    Raquel Dominguez, rdoming930@gmail.com

    Recruiting

Other trials in Uruguay

About this study

This international multi-center registry is used to collect existing information and outcomes for patients undergoing an operation for treatment of injuries to the brain including the blockage of blood flow to an area of the brain, an abnormal ballooning of an artery, abnormal tangling of blood vessels, abnormal formation of blood vessels, tearing of vein, and bleeding in the brain. This information is used to help predict outcomes that undergo an operation for treatment of the above-listed brain injuries. Additionally, the information is used to compare techniques and devices' effects on technical and clinical outcomes.

Being tested
Stroke/Thrombectomy/Aneurysm-specific surgical procedures
Medical subject headings
Stroke, Intracranial Thrombosis, Intracranial Aneurysm

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Stroke/Thrombectomy/Aneurysm-specific surgical proceduresProcedure or surgery

    Participants are retrospectively and/or prospectively entered into registry based on disease indication and respective surgical procedure.

Study groups in NCT04994756
Study groupRoleWhat they receive
StrokeNot described
Receives: Procedure: Stroke/Thrombectomy/Aneurysm-specific surgical procedures
ThrombectomyNot described
Receives: Procedure: Stroke/Thrombectomy/Aneurysm-specific surgical procedures
AneurysmNot described
Receives: Procedure: Stroke/Thrombectomy/Aneurysm-specific surgical procedures

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Post-procedure hemorrhage rate changes

    Researchers examine changes in hemorrhage rates in post-stroke patients

    Measured: 90 days

  2. Occlusion rates

    Measure of how thrombectomy procedure success in relation to reduced occlusion

    Measured: 90 days

  3. Complication rates

    Measure of post-procedure complication rates in stroke/aneurysm patients

    Measured: 90 days

  4. Retreatment rates

    Measure of patient retreatment post-procedure

    Measured: 90 days

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted6 Aug 2021
  2. Study start17 Sep 2019
  3. Primary completion1 Jan 2055 (estimated)
  4. Study completion1 Jan 2055 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Observational
Observational model
Cohort
Time perspective
Prospective
Enrolment
40,000 participants (estimated)
Target duration
90 Days
IDs, dates and publications
ClinicalTrials.gov ID
NCT04994756
Sponsor's protocol ID
Pro00090704
Acronym
STAR
Status last verified
Dec 2025
First submitted
3 Aug 2021
Last updated
24 Dec 2025
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No

Questions about this trial

What is this clinical trial studying?

An observational study of Stroke and Thromboses, Intracranial, run by Medical University of South Carolina at 63 sites in 9 countries.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 2 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: looking for participants now, as of the sponsor's last update on 24 Dec 2025. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 63 sites in United States, Germany, Canada, Japan, Portugal and 4 more countries. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

Contact Alejandro M Spiotta, MD (843-792-9226, spiotta@musc.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Post-procedure hemorrhage rate changes (time frame: 90 days). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT04994756.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 24 Dec 2025.

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Stroke Thrombectomy and Aneurysm Registry | AzTrials