Stroke, CardiovascularNCT05008822
Effect of Motor Imaginary Training on Upper Limb Functions in Stroke
A study testing Motor Imaginary Training Group and Task oriented Training Group in people with Stroke, Cardiovascular, run by Riphah International University at 1 site in Pakistan.
Trial summary
This study will provide knowledge about effectiveness of motor imaginary training in upper limb performance in chronic stroke patients. Very little data is available about the use in Motor Imaginary in post stroke upper limb rehabilitation in Pakistan. Read more about this study
- Who is it for?
- Ages 30 to 60 years
- Conditions the study is for
- Stroke, Cardiovascular
- What is being tested?
- Motor Imaginary Training Group and Task oriented Training Group
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 42 participants
- Where
- 1 sitePakistan
- Study dates
- 1 Oct 2021to 30 Dec 2021
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 30 to 60 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- MCA stroke
- Chronic stroke patients
- Mini-Mental State Examination (MMSE) score >24 points
- Spasticity grade II and III on Modified Ashworth scale
Who cannot join
- Severe cognitive disability such as depression, unilateral neglect, seizure, dementia,
- Any MSK disorder including muscle contracture
Trial locations and contacts
1 site in 1 country.
Pakistan1 site
Physical therapy department of Rehman Medical Institute, Peshawar, Pakistan
Peshawar, Khyber Pakhtunkha, 25000
About this study
Official title: Effect of Motor Imaginary Training on Upper Limb Functions in Stroke Patients
This study will provide knowledge about effectiveness of motor imaginary training in upper limb performance in chronic stroke patients. Very little data is available about the use in Motor Imaginary in post stroke upper limb rehabilitation in Pakistan. Moreover, studies done previously did not specified population of stroke; This study will include MCA stroke patients only, whom upper limb weakness is more prevalent.
Read the detailed description
Motor imagery is a technique for inducing motor activity in response to a certain motor output by producing a mental image of the action without intending to conduct it. It is a cognitive technique that, rather than making a patient to pick up new procedures, promotes neural alterations in order enable the patient to re-acquire motor skills mastered before the CVA or copy the actions of others. Motor imaging training is a sort of therapy in which the patient imagines a gesture or movement in order to learn, reinforce, or improve the movement's performance. A study done in South Korea, published in 2015, revealed that Motor imagery training has a good impact on UL performance by refining functional mobility during stroke rehabilitation. The results suggest that motor imagery training is viable and helpful for improving UL function in CVA patients.
Meta-analysis done in Australia in the year 2013, was supportive of Motor imaginary techniques further convincing that Mental imagery can be a possible intervention for stroke patients given that it being, safe cost-effective \& unlimited practice opportunities. Study done in China in 2017, suggested that clinicians should consider the use of MI in addition to treatment currently used to improve upper extremity functions after stroke as no evidence of side effects or harm was noted . RCT done in year 2006 in USA indicated that for patients with chronic, moderate upper limb impairment after CVA, program of CIMT with mental practice only resulted in decrease impairment, with functional enhancement.
- Conditions
- Stroke, Cardiovascular
- Being tested
- Motor Imaginary Training Group, Task oriented Training Group
- Keywords
- Motor imaginary technique
- Medical subject headings
- Myocardial Infarction
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Motor Imaginary Training GroupOther
After the baseline assessment, the participant will receive Motor Imaginary Program
Task oriented Training GroupOther
After the baseline assessment, the participant will receive MRP and CIMT training
| Study group | Role | What they receive |
|---|---|---|
| Motor Imaginary Training Group | Experimental | After the baseline assessment, the participant will receive Motor Imaginary Program Receives: Other: Motor Imaginary Training Group |
| Task oriented Training Group | Active comparator | After the baseline assessment, the participant will receive MRP and CIMT training Receives: Other: Task oriented Training Group |
What is being measured
The primary outcome is the main question the study is designed to answer.
wolf motor function
The Wolf Motor Function Test (WMFT) is a timed and functional test that assesses upper extremity motor skills in a quantitative manner.
Measured: Change from Baseline to 4th Weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 Aug 2021
- Study start1 Oct 2021
- Primary completion30 Dec 2021
- Study completion30 Dec 2021
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Stroke, CardiovascularStudies of the same condition, open and under way.
- More trials run by Riphah International UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 42 participants (actual)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Misbah ghous, MS, Principal investigator, Riphah International University Islamabad
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05008822
- Sponsor's protocol ID
- REC/0832 Zulfiqar Ali
- Status last verified
- Jan 2022
- First submitted
- 3 Aug 2021
- Last updated
- 26 Jan 2022
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 26 Jan 2022. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Motor Imaginary Training on Upper Limb Functions in Stroke Patients
- ClinicalTrials.gov ID
- NCT05008822
- Acronym / sponsor ID
- REC/0832 Zulfiqar Ali
- Conditions
- Stroke, Cardiovascular
- Keywords
- Motor imaginary technique
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 42 participants (actual)
- Lead sponsor
- Riphah International UniversityUniversity, hospital or other
- Study start
- 1 Oct 2021 (actual)
- Primary completion
- 30 Dec 2021 (actual)
- Study completion
- 30 Dec 2021 (actual)
- First posted
- 17 Aug 2021 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study will provide knowledge about effectiveness of motor imaginary training in upper limb performance in chronic stroke patients. Very little data is available about the use in Motor Imaginary in post stroke upper limb rehabilitation in Pakistan. Moreover, studies done previously did not specified population of stroke; This study will include MCA stroke patients only, whom upper limb weakness is more prevalent.
Detailed description
Motor imagery is a technique for inducing motor activity in response to a certain motor output by producing a mental image of the action without intending to conduct it. It is a cognitive technique that, rather than making a patient to pick up new procedures, promotes neural alterations in order enable the patient to re-acquire motor skills mastered before the CVA or copy the actions of others. Motor imaging training is a sort of therapy in which the patient imagines a gesture or movement in order to learn, reinforce, or improve the movement's performance. A study done in South Korea, published in 2015, revealed that Motor imagery training has a good impact on UL performance by refining functional mobility during stroke rehabilitation. The results suggest that motor imagery training is viable and helpful for improving UL function in CVA patients.
Meta-analysis done in Australia in the year 2013, was supportive of Motor imaginary techniques further convincing that Mental imagery can be a possible intervention for stroke patients given that it being, safe cost-effective \& unlimited practice opportunities. Study done in China in 2017, suggested that clinicians should consider the use of MI in addition to treatment currently used to improve upper extremity functions after stroke as no evidence of side effects or harm was noted . RCT done in year 2006 in USA indicated that for patients with chronic, moderate upper limb impairment after CVA, program of CIMT with mental practice only resulted in decrease impairment, with functional enhancement.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Motor Imaginary Training Group | Experimental | Other: Motor Imaginary Training GroupAfter the baseline assessment, the participant will receive Motor Imaginary Program |
| Task oriented Training Group | Active comparator | Other: Task oriented Training GroupAfter the baseline assessment, the participant will receive MRP and CIMT training |
Who may qualify
- Ages
- 30 to 60 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- MCA stroke
- Chronic stroke patients
- Mini-Mental State Examination (MMSE) score >24 points
- Spasticity grade II and III on Modified Ashworth scale
Key exclusion criteria (2 listed)
- Severe cognitive disability such as depression, unilateral neglect, seizure, dementia,
- Any MSK disorder including muscle contracture
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Motor Imaginary Training GroupAfter the baseline assessment, the participant will receive Motor Imaginary Program | Other | Motor Imaginary Training Group |
| Task oriented Training GroupAfter the baseline assessment, the participant will receive MRP and CIMT training | Other | Task oriented Training Group |
Primary outcome
wolf motor function
Time frame: Change from Baseline to 4th Weeks
The Wolf Motor Function Test (WMFT) is a timed and functional test that assesses upper extremity motor skills in a quantitative manner.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 26 Jan 2022.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Misbah ghous, MS principal investigator
Riphah International University Islamabad
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Motor Imaginary Training Group and Task oriented Training Group in people with Stroke, Cardiovascular, run by Riphah International University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 26 Jan 2022. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
wolf motor function (time frame: Change from Baseline to 4th Weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 26 Jan 2022.