CysticercosisNCT05010811
Two Cases of Pulmonary Cysticercosis Manifesting as Pleural Effusion: Case Report and Literature Review
An observational study of Cysticercosis, run by Second Affiliated Hospital, Zhejiang University, School of Medicine.
Trial summary
Isolation lung cysticercosis reports are rare in literature. Most lung lesions were characterized by nodules. The investigators access one case which was characterized with pulmonary cavity and pleural effusion by Gupta N, et al in 2015 from PUBMED and Medline. Read more about this study
- Who is it for?
- Ages 45 to 67 years
- Conditions the study is for
- Cysticercosis
- How many people
- 2 participants
- Where
- No sites listed yet
- Study dates
- 22 Oct 2016to 28 Apr 2017
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 45 to 67 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Two patients with pleural effusion presenting with chest tightness and chest pain were enrolled in this study with a definitive diagnosis of cysticercosis confirmed by pleural effusion examination
Who may be able to join
- Clinical diagnosis of Pulmonary Cysticercosis。
- With pleural effusion
Who cannot join
- 1.No cysticercosis was found by biopsy or antibody test
About this study
Isolation lung cysticercosis reports are rare in literature. Most lung lesions were characterized by nodules. The investigators access one case which was characterized with pulmonary cavity and pleural effusion by Gupta N, et al in 2015 from PUBMED and Medline. But pleural effusion and exudative lesions is reported for the first time.
Read the detailed description
Cysticercosis is an important public health problem in developing countries. The major involvement sites are the central nervous system and the eyes，although striated muscles and subcutaneous tissues are frequently involved in the disseminated form of disease. Pulmonary involvement in cysticercosis is very rare and ill-defined nodular shadows distributed throughout the lung is the usual radiological presentation. Only one case of cysticercosis presenting as lung cavity with pleural effusion has been reported so far in literature. The investigators describe two cases in which pleural effusion due to cysticercosis were detected on X and CT.
- Conditions
- Cysticercosis
- Keywords
- Cysticercosis, pleural effusion, pulmonary
- Medical subject headings
- Cysticercosis, Pleural Effusion
What is being measured
The primary outcome is the main question the study is designed to answer.
Amount of pleural effusion
cm
Measured: 9 months
Rate of Eosinophil ratio
Percentage（%）
Measured: 9 months
Changes of lesions under chest radiography or CT
no change, change, complete absorption
Measured: 9 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted18 Aug 2021
- Study start22 Oct 2016
- Primary completion18 Jan 2017
- Study completion28 Apr 2017
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for CysticercosisStudies of the same condition, open and under way.
- More trials run by Second Affiliated Hospital, Zhejiang University, School of MedicineThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Retrospective
- Enrolment
- 2 participants (actual)
Sponsor and investigators
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Pingli Wang, MD, Study director, the same research center
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05010811
- Sponsor's protocol ID
- 2016-122
- Status last verified
- Sep 2016
- First submitted
- 11 Jul 2021
- Last updated
- 30 Aug 2021
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 30 Aug 2021. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Two Cases of Pulmonary Cysticercosis Manifesting as Pleural Effusion: Case Report and Literature Review
- ClinicalTrials.gov ID
- NCT05010811
- Acronym / sponsor ID
- 2016-122
- Conditions
- Cysticercosis
- Keywords
- Cysticercosis, pleural effusion, pulmonary
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 2 participants (actual)
- Lead sponsor
- Second Affiliated Hospital, Zhejiang University, School of MedicineUniversity, hospital or other
- Study start
- 22 Oct 2016 (actual)
- Primary completion
- 18 Jan 2017 (actual)
- Study completion
- 28 Apr 2017 (actual)
- First posted
- 18 Aug 2021 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Isolation lung cysticercosis reports are rare in literature. Most lung lesions were characterized by nodules. The investigators access one case which was characterized with pulmonary cavity and pleural effusion by Gupta N, et al in 2015 from PUBMED and Medline. But pleural effusion and exudative lesions is reported for the first time.
Detailed description
Cysticercosis is an important public health problem in developing countries. The major involvement sites are the central nervous system and the eyes，although striated muscles and subcutaneous tissues are frequently involved in the disseminated form of disease. Pulmonary involvement in cysticercosis is very rare and ill-defined nodular shadows distributed throughout the lung is the usual radiological presentation. Only one case of cysticercosis presenting as lung cavity with pleural effusion has been reported so far in literature. The investigators describe two cases in which pleural effusion due to cysticercosis were detected on X and CT.
Study design
- Observational model
- Case only
- Time perspective
- Retrospective
Who may qualify
- Ages
- 45 to 67 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Two patients with pleural effusion presenting with chest tightness and chest pain were enrolled in this study with a definitive diagnosis of cysticercosis confirmed by pleural effusion examination
Key inclusion criteria (2 listed)
- Clinical diagnosis of Pulmonary Cysticercosis。
- With pleural effusion
Key exclusion criteria (1 listed)
- 1.No cysticercosis was found by biopsy or antibody test
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Amount of pleural effusion
Time frame: 9 months
cm
Rate of Eosinophil ratio
Time frame: 9 months
Percentage（%）
Changes of lesions under chest radiography or CT
Time frame: 9 months
no change, change, complete absorption
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 30 Aug 2021.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Pingli Wang, MD study director
the same research center
Questions about this trial
What is this clinical trial studying?
An observational study of Cysticercosis, run by Second Affiliated Hospital, Zhejiang University, School of Medicine.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 30 Aug 2021. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Amount of pleural effusion (time frame: 9 months). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 30 Aug 2021.