Sacroiliac Joint DysfunctionNCT05018780
Muscle Energy Techniques and Sacral Manipulation on Pain, Functional Disability and Quality of Life
A study testing Muscle Energy Technique and Sacral Manipulation in people with Sacroiliac Joint Dysfunction, run by University of Lahore at 1 site in Pakistan.
Trial summary
The study will be randomized clinical trial. This study will be conducted in University of Lahore Teaching Hospital, Lahore, Pakistan. A sample size of 84 will be randomly allocated into two experimental groups, (42 participants in each group), by lottery method. Read more about this study
- Who is it for?
- Ages 20 to 40 years
- Conditions the study is for
- Sacroiliac Joint Dysfunction
- What is being tested?
- Muscle Energy Technique and Sacral Manipulation
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 76 participants
- Where
- 1 sitePakistan
- Study dates
- 1 Jul 2021to 31 Jul 2022
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 40 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Pre-diagnosed cases referred from orthopedic surgeon
- History of fall on buttock, lift and twist maneuver, overzealous kick
- Acute onset of sacral pain within period of 6 weeks
- FABER, Thigh thrust and Gillet sacral joint diagnostic tests must be positive to confirm the SI joint dysfunction before allocation
Who cannot join
- General low back pain, Sciatic pain, piriformis syndrome, Hip joint pathology
- SI joint spondylosis or ankylosing spondylitis
- Red flag signs positive (constant pain without movement, sudden weight loss with pain in time, lower limbs' undefined weakness, neurological signs)
- Structural leg length discrepancy and recent pregnancy
- Participants with other spinal pathologies (e.g. Osteomyelitis, Pott's disease, Cauda equine syndrome, spondylolisthesis or spondyloptosis, Lumbar disc herniation etc.)
- Participants with other systemic illnesses (e.g. cardiovascular disorders, gastrointestinal disorders, renal function disorders, Liver function disorders etc.)
- Participants with traumatic injuries (e.g. fractures, dislocations, sports injuries, road traffic accidents)
Trial locations and contacts
1 site in 1 country.
Pakistan1 site
University of Lahore Teaching Hospital
Lahore, Punjab Province, 55150
About this study
Official title: Immediate and Long Term Effects of Muscle Energy Techniques and Sacral Manipulation on Pain, Functional Disability and Quality of Life in Patients With Sacroiliac Joint Dysfunction: A Randomized Clinical Trial
- The study will be randomized clinical trial. This study will be conducted in University of Lahore Teaching Hospital, Lahore, Pakistan. A sample size of 84 will be randomly allocated into two experimental groups, (42 participants in each group), by lottery method. The participants, randomly allocated to the experimental group A, will receive Muscle Energy Technique (METs), Post isometric relaxation technique specifically, in addition with routine physical therapy as TENS, Hot pack, and strengthening exercises. METs will be performed on piriformis, iliopsoas, erector spine muscles, 1 set of 5 repetitions and 10 seconds hold.
- Participants in experimental group B, will get Sacroiliac joint manipulations with routine physical therapy by principal investigator.
- Both experimental groups will receive twelve treatment sessions and those will be given over a period of six weeks (2 sessions per week, each session of 30-40 minutes).
- Assessor will take outcome measures at baseline and at the end of 6th treatment week through Short Form McGill Pain Questionnaire, Roland-Morris Low Back Pain \& Disability Questionnaire and Short Form Survey; SF-20.
Read the detailed description
- Recruitment: Participants will be recruited and referred by orthopedic surgeon, University of Lahore Teaching Hospital to Physical Therapy Department.
- Screening: Diagnostic \& pain provocative tests (Faber, Thigh thrust and Gillet tests) will be applied on recruited participants for screening. With all three positive tests, participants will be confirmed for positive SI joint dysfunction and will be considered eligible for entering the study.
- The FABER (Patrick's) Test stands for Flexion, Abduction and External Rotation. The participants will be positioned in supine. The leg will be placed in a figure-4 position (hip flexed and abducted with the lateral ankle resting on the contra-lateral thigh proximal to the knee. While stabilizing the opposite side of the pelvis at the anterior superior iliac spine, an external rotation, abduction and posterior force will be then lightly applied to the ipsilateral knee until the end range of motion would achieve. A further few small-amplitude oscillations would be applied to check for pain provocation at the end range of motion. A positive test will be the one that reproduces the participants' pain or limits their range of movement.
- Thigh thrust test is a posterior pelvic pain provocative test. It will be performed with the participant in supine lying, with the hip flexed to 90° (with bent knee) to stretch the posterior structures. By applying axial pressure along the length of the femur, the femur will be used as a lever to push the ilium posteriorly. One hand will be placed beneath the sacrum to fixate its position while the other hand will be used to apply a downward force to the femur. Broadhurst and Bond suggest adding hip adduction towards the mid line while Laslett \& Williams advise to avoid excessive adduction due to discomfort for the participant. Test will be positive if it aggravates the pain in sacroiliac joint.
- The Stork test, also known as the Gillet Test, assesses the movement of the sacroiliac joint between the innominate and sacrum through the clinician's palpation, which may be a useful test for clinical evaluation of a subject's ability to stabilize intra-pelvic motion. The assessment of the Gillet's test involves palpation of the posterior superior iliac spine (PSIS). There are 2 phases to the Gillet's test: the stance phase and the hip flexion or swing phase. To perform this test, the patient will be asked to stand while the examiner will palpate the posterior superior iliac spine (PSIS) with one thumb and will palpate the base of the sacrum with the other thumb medial to the PSIS. The participants will be then instructed to stand on one leg while pulling the hip of the side being palpated into 90° or more of hip flexion. The test will then be repeated on the other side and compared bilaterally. The principal investigator will compare each side for quality and amplitude of movement. The test will be positive when the PSIS on the ipsilateral side (same side of the body) of the knee flexion move minimally in the inferior direction, doesn't move or is associated with pain. A positive test will be an indication of sacroiliac joint hypo-mobility.
- Randomization and Allocation: Afterwards, participants confirming the eligibility criteria will be randomly allocated, through lottery method, into two experimental groups (Group A, Group B).
- Blindness: Study will be single, assessor blinded and an independent investigator will perform randomization and will inform the patients and therapist about the allocation.
- Intervention: The participants, randomly allocated to the experimental group A, will receive METs (Post isometric relaxation technique specifically) in addition with routine physical therapy (TENS, Hot pack, and strengthening exercises). METs will be performed on piriformis, iliopsoas, erector spine muscles, 1 set of 5 repetitions and 10 seconds hold. Participants in experimental group B, will get Sacroiliac joint manipulations with routine physical therapy by principal investigator.
- Duration: Twelve treatment sessions will be given over a period of six weeks (2 sessions per week, each session of 30-40 minutes).
- Outcome Variables and Measures
- Pain (Short Form McGill Pain Questionnaire)
- Functional Disability (Roland-Morris Low Back Pain \& Disability Questionnaire)
- Quality of Life (Short Form Survey; SF-20)
- Outcome measures will be taken at baseline and at the end of last treatment session i.e. 6th week. Collected data will be than analyzed.
- Conditions
- Sacroiliac Joint Dysfunction
- Being tested
- Muscle Energy Technique, Sacral Manipulation
- Keywords
- Sacroilitis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Muscle Energy TechniqueOther
Post isometric relaxation: Patient will be asked to perform isometrics on piriformis, iliopsoas and erector spinae muscles one by one. Each isometric contraction will be held for 10 seconds. After 10 seconds, contraction will be released with an exhalation. These contractions will be repeated for 5 times in one session.
Routine physical therapy including TENS, Hot pack and strengthening exercises will also be delivered along with Muscle Energy Technique.
Sacral ManipulationOther
- To manipulate an iliac anterior rotation displacement sacroiliac joint dysfunction and to restore posterior rotation of the ilium, participant will be positioned in side lying. Therapist will place one hand at Anterior superior iliac supine (ASIS) and the other at Ischial tuberosity. A quick thrust will be applied and ASIS will be pushed posteriorly while Ischial tberosity anteriorly. This will be maintained for 10 to 30 seconds.
- To manipulate an iliac posterior rotation displacement sacroiliac joint dysfunction and to restore anterior rotation of the ilium, participant will be in prone position. One hand of therapist will be at Posterior superior iliac supine (PSIS) and the other one at pubic rami. A quick thrust will be delivered and PSIS will be moved anteriorly while pubic rami posteriorly. This will be maintained for 10 to 30 seconds.
- Routine physical therapy including TENS, Hot pack and strengthening exercises will also be delivered along with Sacral Manipulation.
| Study group | Role | What they receive |
|---|---|---|
| Muscle Energy Technique | Experimental | Post isometric relaxation: Patient will perform isometrics on piriformis, iliopsoas and erector spinae muscles one by one. Each isometric contraction will be held for 10 seconds and than participants will be asked to relax the contraction with an exhalation. This will be repeated five times in one session.
- Routine physical therapy including TENS, Hot pack and strengthening exercises will also be delivered along with Muscle Energy Technique. Receives: Other: Muscle Energy Technique |
| Sacral Manipulation | Experimental | * To manipulate an iliac anterior rotation displacement sacroiliac joint dysfunction and to restore posterior rotation of the ilium, participant will be positioned in side lying. Therapist will place one hand at Anterior superior iliac supine (ASIS) and the other at Ischial tuberosity. A quick thrust will be applied and ASIS will be pushed posteriorly while Ischial tberosity anteriorly. This will be maintained for 10 to 30 seconds.
* To manipulate an iliac posterior rotation displacement sacroiliac joint dysfunction and to restore anterior rotation of the ilium, participant will be in prone position. One hand of therapist will be at Posterior superior iliac supine (PSIS) and the other one at pubic rami. A quick thrust will be delivered and PSIS will be moved anteriorly while pubic rami posteriorly. This will be maintained for 10 to 30 seconds.
* Routine physical therapy including TENS, Hot pack and strengthening exercises will also be delivered along with Sacral Manipulation. Receives: Other: Sacral Manipulation |
What is being measured
The primary outcome is the main question the study is designed to answer.
Short Form McGill Pain Questionnaire
Short form McGill Pain questionnaire (SF-MPQ 2) is 22-items, revised, short version and self-reported measure of pain. It assesses both the quality and intensity of subjective pain. It was initially developed by Dr. Melzack at McGill University in Montreal Canada. The four SF-MPQ-2 score ranges between 0 to 22 where o indicate no pain and 22 indicate worst possible pain.
Measured: 6 weeks
Roland Morris disability and low back pain questionnaire
he Roland-Morris Questionnaire (RMQ) is a 24-items self-administered disability measure. Items would be scored 0 if left blank or 1 if endorsed, for a total RMQ score ranging from 0 to 24; higher scores will be represented as higher levels of pain-related disability.
Measured: 6 weeks
Short Form Survey, SF-20
The SF-20 is short version of SF-36 which is generic patient-reported outcome that qualifies health status and measures health related quality of life. The 20-Item Short Form Health Survey (SF-20) was developed in 1988 for the Medical Outcomes Study (MOS). In this scale, scores across each of its domains would be reported on a 0% to 100% scale, with 0% representing the worst possible score in that domain and 100% the best possible score. The exception to this scoring pattern would be the pain score, for which 0% will represent the best possible score and 100% the worst possible.
Measured: 6 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted24 Aug 2021
- Study start1 Jul 2021
- Primary completion31 Jul 2022
- Study completion31 Jul 2022
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (9)Papers the sponsor has linked to this study.
- Other trials for Sacroiliac Joint DysfunctionStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 76 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Lahore
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Hafiza Sana Ashraf, MS-MSK*, Principal investigator, University of Lahore
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05018780
- Sponsor's protocol ID
- IRB-UOL-FAHS/885/2021
- Status last verified
- Dec 2021
- First submitted
- 18 Aug 2021
- Last updated
- 2 Oct 2025
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Telli H, Huner B, Kuru O. Determination of the Prevalence From Clinical Diagnosis of Sacroiliac Joint Dysfunction in Patients With Lumbar Disc Hernia and an Evaluation of the Effect of This Combination on Pain and Quality of Life. Spine (Phila Pa 1976). 2020 Apr 15;45(8):549-554. doi: 10.1097/BRS.0000000000003309.
PubMed 31842104Thawrani DP, Agabegi SS, Asghar F. Diagnosing Sacroiliac Joint Pain. J Am Acad Orthop Surg. 2019 Feb 1;27(3):85-93. doi: 10.5435/JAAOS-D-17-00132.
PubMed 30278010Orakifar N, Kamali F, Pirouzi S, Jamshidi F. Sacroiliac joint manipulation attenuates alpha-motoneuron activity in healthy women: a quasi-experimental study. Arch Phys Med Rehabil. 2012 Jan;93(1):56-61. doi: 10.1016/j.apmr.2011.05.027.
PubMed 22200384Garcia-Penalver UJ, Palop-Montoro MV, Manzano-Sanchez D. Effectiveness of the Muscle Energy Technique versus Osteopathic Manipulation in the Treatment of Sacroiliac Joint Dysfunction in Athletes. Int J Environ Res Public Health. 2020 Jun 22;17(12):4490. doi: 10.3390/ijerph17124490.
PubMed 32580480Zaidi F, Ahmed I. Effectiveness of muscle energy technique as compared to Maitland mobilisation for the treatment of chronic sacroiliac joint dysfunction. J Pak Med Assoc. 2020 Oct;70(10):1693-1697. doi: 10.5455/JPMA.43722.
PubMed 33159735de Toledo DFA, Kochem FB, Silva JG. High-velocity, low-amplitude manipulation (HVLA) does not alter three-dimensional position of sacroiliac joint in healthy men: A quasi-experimental study. J Bodyw Mov Ther. 2020 Jan;24(1):190-193. doi: 10.1016/j.jbmt.2019.05.020. Epub 2019 May 22.
PubMed 31987543Stratford PW, Riddle DL. A Roland Morris Disability Questionnaire Target Value to Distinguish between Functional and Dysfunctional States in People with Low Back Pain. Physiother Can. 2016;68(1):29-35. doi: 10.3138/ptc.2014-85.
PubMed 27504045Dworkin RH, Turk DC, Trudeau JJ, Benson C, Biondi DM, Katz NP, Kim M. Validation of the Short-form McGill Pain Questionnaire-2 (SF-MPQ-2) in acute low back pain. J Pain. 2015 Apr;16(4):357-66. doi: 10.1016/j.jpain.2015.01.012. Epub 2015 Jan 29.
PubMed 25640290Nejati P, Sartaj E, Imani F, Moeineddin R, Nejati L, Safavi M. Accuracy of the Diagnostic Tests of Sacroiliac Joint Dysfunction. J Chiropr Med. 2020 Mar;19(1):28-37. doi: 10.1016/j.jcm.2019.12.002. Epub 2020 Sep 12.
PubMed 33192189
Study at a glance
From the registry record, last updated by the sponsor on 2 Oct 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Immediate and Long Term Effects of Muscle Energy Techniques and Sacral Manipulation on Pain, Functional Disability and Quality of Life in Patients With Sacroiliac Joint Dysfunction: A Randomized Clinical Trial
- ClinicalTrials.gov ID
- NCT05018780
- Acronym / sponsor ID
- IRB-UOL-FAHS/885/2021
- Conditions
- Sacroiliac Joint Dysfunction
- Keywords
- Sacroilitis
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 76 participants (actual)
- Lead sponsor
- University of LahoreUniversity, hospital or other
- Study start
- 1 Jul 2021 (actual)
- Primary completion
- 31 Jul 2022 (actual)
- Study completion
- 31 Jul 2022 (actual)
- First posted
- 24 Aug 2021 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
- The study will be randomized clinical trial. This study will be conducted in University of Lahore Teaching Hospital, Lahore, Pakistan. A sample size of 84 will be randomly allocated into two experimental groups, (42 participants in each group), by lottery method. The participants, randomly allocated to the experimental group A, will receive Muscle Energy Technique (METs), Post isometric relaxation technique specifically, in addition with routine physical therapy as TENS, Hot pack, and strengthening exercises. METs will be performed on piriformis, iliopsoas, erector spine muscles, 1 set of 5 repetitions and 10 seconds hold.
- Participants in experimental group B, will get Sacroiliac joint manipulations with routine physical therapy by principal investigator.
- Both experimental groups will receive twelve treatment sessions and those will be given over a period of six weeks (2 sessions per week, each session of 30-40 minutes).
- Assessor will take outcome measures at baseline and at the end of 6th treatment week through Short Form McGill Pain Questionnaire, Roland-Morris Low Back Pain \& Disability Questionnaire and Short Form Survey; SF-20.
Detailed description
- Recruitment: Participants will be recruited and referred by orthopedic surgeon, University of Lahore Teaching Hospital to Physical Therapy Department.
- Screening: Diagnostic \& pain provocative tests (Faber, Thigh thrust and Gillet tests) will be applied on recruited participants for screening. With all three positive tests, participants will be confirmed for positive SI joint dysfunction and will be considered eligible for entering the study.
- The FABER (Patrick's) Test stands for Flexion, Abduction and External Rotation. The participants will be positioned in supine. The leg will be placed in a figure-4 position (hip flexed and abducted with the lateral ankle resting on the contra-lateral thigh proximal to the knee. While stabilizing the opposite side of the pelvis at the anterior superior iliac spine, an external rotation, abduction and posterior force will be then lightly applied to the ipsilateral knee until the end range of motion would achieve. A further few small-amplitude oscillations would be applied to check for pain provocation at the end range of motion. A positive test will be the one that reproduces the participants' pain or limits their range of movement.
- Thigh thrust test is a posterior pelvic pain provocative test. It will be performed with the participant in supine lying, with the hip flexed to 90° (with bent knee) to stretch the posterior structures. By applying axial pressure along the length of the femur, the femur will be used as a lever to push the ilium posteriorly. One hand will be placed beneath the sacrum to fixate its position while the other hand will be used to apply a downward force to the femur. Broadhurst and Bond suggest adding hip adduction towards the mid line while Laslett \& Williams advise to avoid excessive adduction due to discomfort for the participant. Test will be positive if it aggravates the pain in sacroiliac joint.
- The Stork test, also known as the Gillet Test, assesses the movement of the sacroiliac joint between the innominate and sacrum through the clinician's palpation, which may be a useful test for clinical evaluation of a subject's ability to stabilize intra-pelvic motion. The assessment of the Gillet's test involves palpation of the posterior superior iliac spine (PSIS). There are 2 phases to the Gillet's test: the stance phase and the hip flexion or swing phase. To perform this test, the patient will be asked to stand while the examiner will palpate the posterior superior iliac spine (PSIS) with one thumb and will palpate the base of the sacrum with the other thumb medial to the PSIS. The participants will be then instructed to stand on one leg while pulling the hip of the side being palpated into 90° or more of hip flexion. The test will then be repeated on the other side and compared bilaterally. The principal investigator will compare each side for quality and amplitude of movement. The test will be positive when the PSIS on the ipsilateral side (same side of the body) of the knee flexion move minimally in the inferior direction, doesn't move or is associated with pain. A positive test will be an indication of sacroiliac joint hypo-mobility.
- Randomization and Allocation: Afterwards, participants confirming the eligibility criteria will be randomly allocated, through lottery method, into two experimental groups (Group A, Group B).
- Blindness: Study will be single, assessor blinded and an independent investigator will perform randomization and will inform the patients and therapist about the allocation.
- Intervention: The participants, randomly allocated to the experimental group A, will receive METs (Post isometric relaxation technique specifically) in addition with routine physical therapy (TENS, Hot pack, and strengthening exercises). METs will be performed on piriformis, iliopsoas, erector spine muscles, 1 set of 5 repetitions and 10 seconds hold. Participants in experimental group B, will get Sacroiliac joint manipulations with routine physical therapy by principal investigator.
- Duration: Twelve treatment sessions will be given over a period of six weeks (2 sessions per week, each session of 30-40 minutes).
- Outcome Variables and Measures
- Pain (Short Form McGill Pain Questionnaire)
- Functional Disability (Roland-Morris Low Back Pain \& Disability Questionnaire)
- Quality of Life (Short Form Survey; SF-20)
- Outcome measures will be taken at baseline and at the end of last treatment session i.e. 6th week. Collected data will be than analyzed.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Muscle Energy Technique | Experimental | Other: Muscle Energy TechniquePost isometric relaxation: Patient will perform isometrics on piriformis, iliopsoas and erector spinae muscles one by one. Each isometric contraction will be held for 10 seconds and than participants will be asked to relax the contraction with an exhalation. This will be repeated five times in one session. - Routine physical therapy including TENS, Hot pack and strengthening exercises will also be delivered along with Muscle Energy Technique. |
| Sacral Manipulation | Experimental | Other: Sacral Manipulation* To manipulate an iliac anterior rotation displacement sacroiliac joint dysfunction and to restore posterior rotation of the ilium, participant will be positioned in side lying. Therapist will place one hand at Anterior superior iliac supine (ASIS) and the other at Ischial tuberosity. A quick thrust will be applied and ASIS will be pushed posteriorly while Ischial tberosity anteriorly. This will be maintained for 10 to 30 seconds. * To manipulate an iliac posterior rotation displacement sacroiliac joint dysfunction and to restore anterior rotation of the ilium, participant will be in prone position. One hand of therapist will be at Posterior superior iliac supine (PSIS) and the other one at pubic rami. A quick thrust will be delivered and PSIS will be moved anteriorly while pubic rami posteriorly. This will be maintained for 10 to 30 seconds. * Routine physical therapy including TENS, Hot pack and strengthening exercises will also be delivered along with Sacral Manipulation. |
Who may qualify
- Ages
- 20 to 40 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- Pre-diagnosed cases referred from orthopedic surgeon
- History of fall on buttock, lift and twist maneuver, overzealous kick
- Acute onset of sacral pain within period of 6 weeks
- FABER, Thigh thrust and Gillet sacral joint diagnostic tests must be positive to confirm the SI joint dysfunction before allocation
Key exclusion criteria (7 listed)
- General low back pain, Sciatic pain, piriformis syndrome, Hip joint pathology
- SI joint spondylosis or ankylosing spondylitis
- Red flag signs positive (constant pain without movement, sudden weight loss with pain in time, lower limbs' undefined weakness, neurological signs)
- Structural leg length discrepancy and recent pregnancy
- Participants with other spinal pathologies (e.g. Osteomyelitis, Pott's disease, Cauda equine syndrome, spondylolisthesis or spondyloptosis, Lumbar disc herniation etc.)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Muscle Energy TechniquePost isometric relaxation: Patient will be asked to perform isometrics on piriformis, iliopsoas and erector spinae muscles one by one. Each isometric contraction will be held for 10 seconds. After 10 seconds, contraction will be released with an exhalation. These contractions will be repeated for 5 times in one session. Routine physical therapy including TENS, Hot pack and strengthening exercises will also be delivered along with Muscle Energy Technique. | Other | Muscle Energy Technique |
| Sacral Manipulation* To manipulate an iliac anterior rotation displacement sacroiliac joint dysfunction and to restore posterior rotation of the ilium, participant will be positioned in side lying. Therapist will place one hand at Anterior superior iliac supine (ASIS) and the other at Ischial tuberosity. A quick thrust will be applied and ASIS will be pushed posteriorly while Ischial tberosity anteriorly. This will be maintained for 10 to 30 seconds. * To manipulate an iliac posterior rotation displacement sacroiliac joint dysfunction and to restore anterior rotation of the ilium, participant will be in prone position. One hand of therapist will be at Posterior superior iliac supine (PSIS) and the other one at pubic rami. A quick thrust will be delivered and PSIS will be moved anteriorly while pubic rami posteriorly. This will be maintained for 10 to 30 seconds. * Routine physical therapy including TENS, Hot pack and strengthening exercises will also be delivered along with Sacral Manipulation. | Other | Sacral Manipulation |
Primary outcome
Short Form McGill Pain Questionnaire
Time frame: 6 weeks
Short form McGill Pain questionnaire (SF-MPQ 2) is 22-items, revised, short version and self-reported measure of pain. It assesses both the quality and intensity of subjective pain. It was initially developed by Dr. Melzack at McGill University in Montreal Canada. The four SF-MPQ-2 score ranges between 0 to 22 where o indicate no pain and 22 indicate worst possible pain.
Roland Morris disability and low back pain questionnaire
Time frame: 6 weeks
he Roland-Morris Questionnaire (RMQ) is a 24-items self-administered disability measure. Items would be scored 0 if left blank or 1 if endorsed, for a total RMQ score ranging from 0 to 24; higher scores will be represented as higher levels of pain-related disability.
Short Form Survey, SF-20
Time frame: 6 weeks
The SF-20 is short version of SF-36 which is generic patient-reported outcome that qualifies health status and measures health related quality of life. The 20-Item Short Form Health Survey (SF-20) was developed in 1988 for the Medical Outcomes Study (MOS). In this scale, scores across each of its domains would be reported on a 0% to 100% scale, with 0% representing the worst possible score in that domain and 100% the best possible score. The exception to this scoring pattern would be the pain score, for which 0% will represent the best possible score and 100% the worst possible.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Oct 2025.
- Background: PubMed 31842104Telli H, Huner B, Kuru O. Determination of the Prevalence From Clinical Diagnosis of Sacroiliac Joint Dysfunction in Patients With Lumbar Disc Hernia and an Evaluation of the Effect of This Combination on Pain and Quality of Life. Spine (Phila Pa 1976). 2020 Apr 15;45(8):549-554. doi: 10.1097/BRS.0000000000003309.
- Background: PubMed 30278010Thawrani DP, Agabegi SS, Asghar F. Diagnosing Sacroiliac Joint Pain. J Am Acad Orthop Surg. 2019 Feb 1;27(3):85-93. doi: 10.5435/JAAOS-D-17-00132.
- Background: PubMed 22200384Orakifar N, Kamali F, Pirouzi S, Jamshidi F. Sacroiliac joint manipulation attenuates alpha-motoneuron activity in healthy women: a quasi-experimental study. Arch Phys Med Rehabil. 2012 Jan;93(1):56-61. doi: 10.1016/j.apmr.2011.05.027.
- Background: PubMed 32580480Garcia-Penalver UJ, Palop-Montoro MV, Manzano-Sanchez D. Effectiveness of the Muscle Energy Technique versus Osteopathic Manipulation in the Treatment of Sacroiliac Joint Dysfunction in Athletes. Int J Environ Res Public Health. 2020 Jun 22;17(12):4490. doi: 10.3390/ijerph17124490.
- Background: PubMed 33159735Zaidi F, Ahmed I. Effectiveness of muscle energy technique as compared to Maitland mobilisation for the treatment of chronic sacroiliac joint dysfunction. J Pak Med Assoc. 2020 Oct;70(10):1693-1697. doi: 10.5455/JPMA.43722.
- Background: PubMed 31987543de Toledo DFA, Kochem FB, Silva JG. High-velocity, low-amplitude manipulation (HVLA) does not alter three-dimensional position of sacroiliac joint in healthy men: A quasi-experimental study. J Bodyw Mov Ther. 2020 Jan;24(1):190-193. doi: 10.1016/j.jbmt.2019.05.020. Epub 2019 May 22.
- Background: PubMed 27504045Stratford PW, Riddle DL. A Roland Morris Disability Questionnaire Target Value to Distinguish between Functional and Dysfunctional States in People with Low Back Pain. Physiother Can. 2016;68(1):29-35. doi: 10.3138/ptc.2014-85.
- Background: PubMed 25640290Dworkin RH, Turk DC, Trudeau JJ, Benson C, Biondi DM, Katz NP, Kim M. Validation of the Short-form McGill Pain Questionnaire-2 (SF-MPQ-2) in acute low back pain. J Pain. 2015 Apr;16(4):357-66. doi: 10.1016/j.jpain.2015.01.012. Epub 2015 Jan 29.
- Background: PubMed 33192189Nejati P, Sartaj E, Imani F, Moeineddin R, Nejati L, Safavi M. Accuracy of the Diagnostic Tests of Sacroiliac Joint Dysfunction. J Chiropr Med. 2020 Mar;19(1):28-37. doi: 10.1016/j.jcm.2019.12.002. Epub 2020 Sep 12.
- Individual participant dataSharing planned: No
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Active, not recruitingObservational study
Post-Market Clinical Study on a Modular SI Joint Fusion System
Sacroiliitis, Sacroiliac Joint Dysfunction
Not yet recruitingObservational study
Does Injection Target Matter in Sacroiliac Joint Dysfunction?
Sacroiliac Joint Dysfunction, Multifidus
Enrolling by invitationPhase 2
Effect of Post-Radiofrequency Corticosteroid Injection on the Incidence of Post-Neurotomy Neuritis
Facet Joint Pain, Arthropathy
Recruiting
Effects of Core Stability and Pelvic Clock Exercises in Sacroiliac Joint Dysfunction
Sacroiliac Joint Dysfunction
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Hafiza Sana Ashraf, MS-MSK* principal investigator
University of Lahore
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Muscle Energy Technique and Sacral Manipulation in people with Sacroiliac Joint Dysfunction, run by University of Lahore at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 2 Oct 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Short Form McGill Pain Questionnaire (time frame: 6 weeks). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT05018780, which also lists 9 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Oct 2025; AzTrials last refreshed its copy on 1 Nov 2026.