Bariatric Surgery CandidateNCT05034081

Impact Of Post-Bariatric Body Contouring Procedures on Patient Body Weight and Metabolism

A study testing body contouring in people with Bariatric Surgery Candidate, run by Assiut University at 1 site in Egypt.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record

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Trial summary

Is post-bariatric body contouring surgery prevent weight regain or no, and what is the effect on the patient's Metabolism? Few literature studies report body contouring surgery to be positively associated with maintained weight loss after obesity surgery but the measures of outcomes are diverse, and the collective… Read more about this study

Who is it for?: Ages 20 to 60 yearsHealthy volunteers can take part
Conditions the study is for: Bariatric Surgery Candidate
What is being tested?: body contouring
Type of treatment: Surgery or procedure
Could I receive a placebo?: No, everyone receives an active treatment
How many people: 60 participants
Where: 1 siteEgypt
Study dates: 1 Sep 2021to 15 Aug 2025
Phase: Interventional
Are there results?: Yes, posted in the registrySummary in the doctors' view

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

Ages 20 to 60 years
All sexes
Healthy volunteers accepted
Adult

Who may be able to join

Post-bariatric (sleeve) patients will do body contouring surgery.
Post-bariatric patients has been stable within 5 kg for 3 months
Age between 20-60 years old.
patients use the determinant fixed diet.

Who cannot join

Age below 20 and above 60 years old.
Non-compliance with the fixed diet.
psychotic patients.
Female patients seeking pregnancy.
Endocrine causes of obesity.
Bariatric surgery other than sleeve.

Trial locations and contacts

1 site in 1 country.

Egypt1 site

Assiut University
Asyut, Asyut Governorate, 088

Other trials in Egypt

About this study

The changes in gastrointestinal hormones, adipokines, and cytokines as well as in hypothalamic neuropeptides and neurotransmitters resemble the changes observed in the anorexia/cachexia, suggesting that bariatric surgery triggers a catabolic state responsible for loss of appetite and prolonged body weight reduction.

Weight regain after gastric bypass surgery occurs in about half of all patients within 2 years. About 50% of patients eventually gain a little weight back after hitting their low point. We need a more thorough evaluation to determine what factors - medical, psychological, lifestyle - are involved in the weight gain. One of the factors that seem to be responsible for the degree and durability of weight loss is post-bariatric body contouring procedures. However, metabolic consequences of removing excess subcutaneous adipose tissue by body contouring procedures have to a lesser extent been explored

Conditions: Bariatric Surgery Candidate
Being tested: body contouring
Keywords: Bariatric, Weight regain, Metabolism

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

body contouringProcedure or surgery
any post-bariatric body contouring surgery included

Study groups in NCT05034081
Study group	Role	What they receive
group A	Experimental	to know the effect of post-bariatric body contouring surgery on weight loss and metabolism Receives: Procedure: body contouring
group B	No intervention	compare this group of patients with group A to detect weight changes and metabolic changes without any post-bariatric intervention

What is being measured

The primary outcome is the main question the study is designed to answer.

Weight Changes by Kilograms
to know the effect of post-bariatric body contouring surgery in weight. Detect the weight cahnges of the patient 3 and 6 months after body contouring surgery and body mass index also measured
Measured: 6 months
Level of Tumor Necrotizing Factor Alfa in Blood
Its a clinical laboratory investigation will be done before the body contouring surgeries and 3 and 6 months after. Tumor necrotizing factor alfa increase afer bariatric surgery and we want to know if its complete on increasing after body contouring surgeries or decresae . Tnf-a is measured by pg/ml
Measured: 6 months
Level of BNP in Blood
Its a clinical laboratory investigation will be done before the body contouring surgeries and 3 and 6 months after. BNP highly increase with catabolism after bariatric surgery and we want to know the effect of body contouring surgeries in the level of BNP. BNP unit is pg/ml
Measured: 6 months
Level of High Sensitive CRP in Blood
Its a clinical laboratory investigation will be done before the body contouring surgeries and 3 and 6 months after. hsCRP increase with catabolism after bariatric surgery and we want to know the effect of body contouring surgeries in blood level of hsCRp. The unit of hsCRP is mg/dl.
Measured: 6 months

Secondary outcomes (1)

Patient Satisfaction Score
From 1 to 5 .
1 very dissatisfied 5 very satisfied Increase in number means increase satisfaction.
Measured: 6 months

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

1 Sep 202115 Aug 2025

First posted5 Sep 2021
Study start1 Sep 2021
Primary completion15 Aug 2024
Study completion15 Aug 2025

Resources

Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
Posted resultsParticipant flow, outcome measures and adverse events reported by the sponsor.
Other trials for Bariatric Surgery CandidateStudies of the same condition, open and under way.
More trials run by Assiut UniversityThe sponsor's other registered studies.
What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design

Study type: Interventional
Phase: Phase N/A
Primary purpose: Prevention
Allocation: Randomised
Intervention model: Parallel groups
Masking: None (open label)
Enrolment: 60 participants (actual)

IDs, dates and publications

ClinicalTrials.gov ID: NCT05034081
Sponsor's protocol ID: AUN
Status last verified: Apr 2026
First submitted: 18 Aug 2021
Last updated: 1 May 2026
Results posted: Yes, on ClinicalTrials.gov
Data monitoring committee: Yes
FDA-regulated drug: No
FDA-regulated device: No
Individual data sharing: No: It will be shared as numbers and the name of participants will not shared

Want to know more?

The sponsor has not listed a contact. The official record may have more details.

Talk to your doctor first and take this page with you. Only the study team can confirm whether you can join.

Questions to ask the study team

What is the study trying to find out?
What would I need to do, and how often would I visit?
Could I receive a placebo instead of the treatment?
What are the possible risks and benefits for me?
Will it cost me anything? Are travel or time paid for?
Can I keep seeing my own doctor during the study?
What happens when the study ends?

See locations

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All Bariatric Surgery Candidate trials

Study at a glance

From the registry record, last updated by the sponsor on 1 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.

Official title: Impact Of Post-Bariatric Body Contouring Procedures on Patient Body Weight and Metabolism
ClinicalTrials.gov ID: NCT05034081
Acronym / sponsor ID: AUN
Conditions: Bariatric Surgery Candidate
Keywords: Bariatric, Weight regain, Metabolism
Study type: Interventional
Recruitment status: Completed
Enrolment: 60 participants (actual)
Lead sponsor: Assiut UniversityUniversity, hospital or other
Study start: 1 Sep 2021 (actual)
Primary completion: 15 Aug 2024 (actual)
Study completion: 15 Aug 2025 (actual)
First posted: 5 Sep 2021 (actual)
Results: Posted 1 May 2026

Clinical summary

The research question as the sponsor registered it. This describes what the study plans to test, not what it found.

Study design

Primary purpose: Prevention
Allocation: Randomised
Intervention model: Parallel groups
Masking: None (open label)
Number of arms: 2

Arm	Type	Receives
group A	Experimental	Procedure: body contouringto know the effect of post-bariatric body contouring surgery on weight loss and metabolism
group B	No intervention	–compare this group of patients with group A to detect weight changes and metabolic changes without any post-bariatric intervention

Who may qualify

Ages: 20 to 60 years
Sex: All
Healthy volunteers: Accepted
Age groups: Adult

Key inclusion criteria (4 listed)

Post-bariatric (sleeve) patients will do body contouring surgery.
Post-bariatric patients has been stable within 5 kg for 3 months
Age between 20-60 years old.
patients use the determinant fixed diet.

Key exclusion criteria (6 listed)

Age below 20 and above 60 years old.
Non-compliance with the fixed diet.
psychotic patients.
Female patients seeking pregnancy.
Endocrine causes of obesity.

Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.

Interventions

Intervention	Type	Arms
body contouringany post-bariatric body contouring surgery included	Procedure or surgery	group A

Primary outcome

Weight Changes by Kilograms
Time frame: 6 months
to know the effect of post-bariatric body contouring surgery in weight. Detect the weight cahnges of the patient 3 and 6 months after body contouring surgery and body mass index also measured
Level of Tumor Necrotizing Factor Alfa in Blood
Time frame: 6 months
Its a clinical laboratory investigation will be done before the body contouring surgeries and 3 and 6 months after. Tumor necrotizing factor alfa increase afer bariatric surgery and we want to know if its complete on increasing after body contouring surgeries or decresae . Tnf-a is measured by pg/ml
Level of BNP in Blood
Time frame: 6 months
Its a clinical laboratory investigation will be done before the body contouring surgeries and 3 and 6 months after. BNP highly increase with catabolism after bariatric surgery and we want to know the effect of body contouring surgeries in the level of BNP. BNP unit is pg/ml
Level of High Sensitive CRP in Blood
Time frame: 6 months
Its a clinical laboratory investigation will be done before the body contouring surgeries and 3 and 6 months after. hsCRP increase with catabolism after bariatric surgery and we want to know the effect of body contouring surgeries in blood level of hsCRp. The unit of hsCRP is mg/dl.

1 secondary outcome

Patient Satisfaction Score
Time frame: 6 months

Results and safety

Results posted to the registry on 1 May 2026, as reported by the sponsor. Figures are copied from the record, not re-analysed. Full results on ClinicalTrials.gov.

Participant flow

Group	Started	Completed
Group A	30	30
Group B	30	30

Primary outcome: Weight Changes by Kilograms

Time frame: 6 months. Mean (Standard Deviation). Unit: Kilo gram

Measure	Group A n = 30	Group B n = 30
Pre operative weight	94.3 (12.41)	96.17 (6.7)
3 months after body contouring	96.27 (6.87)	89.4 (12.44)
6 months after body contouring	96.67 (6.93)	86.3 (12.08)

Primary outcome: Level of Tumor Necrotizing Factor Alfa in Blood

Time frame: 6 months. Mean (Standard Deviation). Unit: Pico gram per ml

Measure	Group A n = 30	Group B n = 30
Pre operative tnf alfa	8.61 (1.56)	9.07 (2)
3 months after body contouring	5.84 (1.43)	6.93 (1.35)
6 months after body contouring	5.3 (1.76)	6.86 (1.4)

Primary outcome: Level of BNP in Blood

Time frame: 6 months. Mean (Standard Deviation). Unit: Pico gram per ml

Measure	Group A n = 30	Group B n = 30
Pre operative BNP	64 (18.78)	59.03 (18.13)
3 months after body contouring	63.4 (17.71)	70.07 (19.14)
6 months after body contouring	69.33 (18.13)	75.13 (19.01)

Primary outcome: Level of High Sensitive CRP in Blood

Time frame: 6 months. Mean (Standard Deviation). Unit: Mg per dl

Measure	Group A n = 30	Group B n = 30
Pre operative hscrp	1.13 (0.75)	1.23 (1)
3 months after body contouring	0.93 (0.54)	0.58 (0.36)
6 months after body contouring	0.87 (0.52)	0.52 (0.37)

1 secondary outcome is reported in the full results.

Adverse events

Time frame: 6 months. Other adverse events reported at 0% frequency or more

Group	Serious adverse events	Other adverse events	Deaths
Group A	0 of 30 (0%)	10 of 30 (33.3%)	0 of 30
Group B	0 of 30 (0%)	12 of 30 (40%)	0 of 30

Loading the posted results from ClinicalTrials.gov…

Research links

Official record on ClinicalTrials.govLast updated by the sponsor 1 May 2026.
Posted resultsParticipant flow, baseline, all outcome measures and adverse events.
Individual participant dataSharing planned: No. It will be shared as numbers and the name of participants will not shared

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Referral and contact

AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.

Mohamed Shadad, Master study director

Assiut University

1 site in 1 country: see every site and its status.

Questions about this trial

What is this clinical trial studying?

A study testing body contouring in people with Bariatric Surgery Candidate, run by Assiut University at 1 site in Egypt.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 4 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 1 May 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

Yes. Results are posted in the registry (first posted 1 May 2026). A summary is in the For doctors view, and the full results are on ClinicalTrials.gov.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Weight Changes by Kilograms (time frame: 6 months). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT05034081.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 1 May 2026.