WrinkleNCT05039476
Study to Identify if Chemist Confessions Retinol Cream Works to Improve the Appearance of Early Signs of Aging.
A study testing Retinol face cream in people with Wrinkle and Aging, run by Chemist Confessions, Inc. at 1 site in United States.
Trial summary
Chemist Confessions has developed a retinol cream with the aim to improve the appearance of early signs of aging, such as fine lines, dark spots, hyperpigmentation, and crow's feet. Read more about this study
- Who is it for?
- Ages 30 to 50 years, women onlyHealthy volunteers can take part
- What is being tested?
- Retinol face cream
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 35 participants
- Where
- 1 siteUnited States
- Study dates
- 1 Jul 2022to 30 Nov 2022
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 30 to 50 years
- Women only
- Healthy volunteers accepted
- Adult
Who may be able to join
- Female between 30-50 years old
- Must be in good general health
- Must experience early-stage wrinkles that are not treated by topical or oral prescription drugs/medication
- May experience hyperpigmentation, dark spots and dark circles
- Must maintain the following skincare routine containing: cleansing, allowed moisturizer and study specific sunscreen
- Must use study provided sunscreen daily
Show all 15Show fewer
- Must discontinue the use of other retinoids 4 weeks before the study start date
- Must have some general knowledge of retinoid use
- Must be willing to comply with the requirements of the protocol
- Must be able to communicate in English
- Must be able to tell left from right
- Must willing to add the retinoid cream to their skincare routine
- Must provide written informed consent form (ICF)
- Is willing and able to share feedback and take skin pictures via the used technology portal
- Must be willing to refrain from using products with chemical exfoliants glycolic acid and lactic acid during the duration of the study
Who cannot join
- Unwilling to provide consent
- Unwilling to add the retinoid cream to their normal skincare routine
- Unwilling to follow the routine of the protocol
- Uses moisturizers that include chemical exfoliating ingredients such as glycolic acid, lactic acid or salicylic acid
- Use of other oral retinoids
- Use of prescription medication relevant to the skin
Show all 13Show fewer
- Undergoing any cosmetic procedures during the study including Botox, laser or chemical peel treatments
- Deep-set of wrinkles
- Use of prescription drug (topical or oral) that is targeted at any sort of skin condition (for example retinoids)
- Is pregnant or nursing, or attempting a pregnancy
- Used retinoids before with an adverse reaction
- Has a self-identified sensitive skin type
- Has any learning and/or cognitive difficulties that prevent him/her reading and understanding questionnaires and surveys (e.g. dementia)
Trial locations and contacts
1 site in 1 country.
About this study
Chemist Confessions has developed a retinol cream with the aim to improve the appearance of early signs of aging, such as fine lines, dark spots, hyperpigmentation, and crow's feet. In this phase, Chemist Confessions plans to collect self-reported outcomes and photographic images to understand the assessment of the efficacy of treatment from the participant's perspective, and if participants see an improvement in their fine lines, wrinkles, dark spots, hyperpigmentation, and crow's feet.
Read the detailed description
Based on a review of existing literature and previous studies, retinol has been found to have positive effects, however, due to study limitations, there are also conflicting results. Therefore, in this study, participants will receive Chemist Confessions retinol cream to understand if the Chemist Confessions cream has an impact on the participant's skin, and even potentially reduces fine lines, wrinkles, dark spots, hyperpigmentation, and crow's feet of the skin, and also to understand concepts considered essential by individuals taking retinol products.
- Being tested
- Retinol face cream, Placebo face cream
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Retinol face creamDietary supplement
Retinol face cream
Placebo face creamDietary supplement
Placebo face cream
| Study group | Role | What they receive |
|---|---|---|
| Retinol face cream | Active comparator | Retinol face cream on one half of the participant's face Receives: Dietary Supplement: Retinol face cream |
| Placebo face cream | Placebo comparator | Placebo face cream on one half of the participant's face Receives: Dietary Supplement: Placebo face cream |
What is being measured
The primary outcome is the main question the study is designed to answer.
Improvement of skin appearance of early signs of aging
The primary objective of this study is to understand if Chemist Confessions retinol cream is capable of improving the appearance of early signs of aging such as fine lines, dark spots, wrinkles, hyperpigmentation and crow's feet, and to determine if it helps to improve the overall skin health by promoting hydrated, brightened skin for study participants.
To evaluate the improvement of this outcome measure VISIA imaging will be used.
Measured: 12 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted9 Sep 2021
- Study start1 Jul 2022
- Primary completion30 Nov 2022
- Study completion30 Nov 2022
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for WrinkleStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Single group
- Model description
- Split face intervention
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 35 participants (actual)
Sponsor and investigators
- Lead sponsor
- Chemist Confessions, Inc.
- Sponsor type
- Industry (pharma, biotech, devices)
- Collaborators
- Citruslabs
- Responsible party
- Sponsor
- Investigators
- Susanne Mitschke, MSc, Principal investigator, Citruslabs
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05039476
- Sponsor's protocol ID
- 20218Chemist
- Status last verified
- Feb 2023
- First submitted
- 1 Sep 2021
- Last updated
- 8 Feb 2023
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 8 Feb 2023. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Study to Identify if Chemist Confessions Retinol Cream Works to Improve the Appearance of Early Signs of Aging.
- ClinicalTrials.gov ID
- NCT05039476
- Acronym / sponsor ID
- 20218Chemist
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 35 participants (actual)
- Lead sponsor
- Chemist Confessions, Inc.Industry (pharma, biotech, devices)
- Collaborators
- Citruslabs
- Study start
- 1 Jul 2022 (actual)
- Primary completion
- 30 Nov 2022 (actual)
- Study completion
- 30 Nov 2022 (actual)
- First posted
- 9 Sep 2021 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Chemist Confessions has developed a retinol cream with the aim to improve the appearance of early signs of aging, such as fine lines, dark spots, hyperpigmentation, and crow's feet. In this phase, Chemist Confessions plans to collect self-reported outcomes and photographic images to understand the assessment of the efficacy of treatment from the participant's perspective, and if participants see an improvement in their fine lines, wrinkles, dark spots, hyperpigmentation, and crow's feet.
Detailed description
Based on a review of existing literature and previous studies, retinol has been found to have positive effects, however, due to study limitations, there are also conflicting results. Therefore, in this study, participants will receive Chemist Confessions retinol cream to understand if the Chemist Confessions cream has an impact on the participant's skin, and even potentially reduces fine lines, wrinkles, dark spots, hyperpigmentation, and crow's feet of the skin, and also to understand concepts considered essential by individuals taking retinol products.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Single group
- Masking
- Single blind (participant)
- Number of arms
- 2
- Model description
- Split face intervention
| Arm | Type | Receives |
|---|---|---|
| Retinol face cream | Active comparator | Dietary Supplement: Retinol face creamRetinol face cream on one half of the participant's face |
| Placebo face cream | Placebo comparator | Dietary Supplement: Placebo face creamPlacebo face cream on one half of the participant's face |
Who may qualify
- Ages
- 30 to 50 years
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (15 listed)
- Female between 30-50 years old
- Must be in good general health
- Must experience early-stage wrinkles that are not treated by topical or oral prescription drugs/medication
- May experience hyperpigmentation, dark spots and dark circles
- Must maintain the following skincare routine containing: cleansing, allowed moisturizer and study specific sunscreen
Key exclusion criteria (13 listed)
- Unwilling to provide consent
- Unwilling to add the retinoid cream to their normal skincare routine
- Unwilling to follow the routine of the protocol
- Uses moisturizers that include chemical exfoliating ingredients such as glycolic acid, lactic acid or salicylic acid
- Use of other oral retinoids
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Retinol face creamRetinol face cream | Dietary supplement | Retinol face cream |
| Placebo face creamPlacebo face cream | Dietary supplement | Placebo face cream |
Primary outcome
Improvement of skin appearance of early signs of aging
Time frame: 12 weeks
The primary objective of this study is to understand if Chemist Confessions retinol cream is capable of improving the appearance of early signs of aging such as fine lines, dark spots, wrinkles, hyperpigmentation and crow's feet, and to determine if it helps to improve the overall skin health by promoting hydrated, brightened skin for study participants. To evaluate the improvement of this outcome measure VISIA imaging will be used.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 8 Feb 2023.
- Individual participant dataSharing planned: No
Related trials for Wrinkle
Active, not recruiting
A Prospective Controlled Study to Evaluate the Safety and Effectiveness of Thermage® FLX Radiofrequency Treatment
Wrinkle, Lax Skin
Not yet recruitingPhase 2
Can TrenibotulinumtoxinE Reverse OnabotulinumtoxinA Effect in Treating Lateral Canthal Lines?
Wrinkles and Rhytides
Active, not recruiting
Clinical Study to Evaluate the Safety and Efficacy of Candela Technology
Hair Reduction, Tattoo Removal
Active, not recruiting
Clinical Feasibility Study to Evaluate the Safety and Performance of the Profound Matrix System
Skin Laxity, Wrinkle
Not yet recruiting
A Study to Evaluate the Safety and Effectiveness of GP0112 for Cheek Augmentation and Correction of Midface Contour Deficiencies
Cheek Wrinkles, Midface Contour Deficiencies
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Susanne Mitschke, MSc principal investigator
Citruslabs
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Retinol face cream in people with Wrinkle and Aging, run by Chemist Confessions, Inc. at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 15 inclusion and 13 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 8 Feb 2023. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Improvement of skin appearance of early signs of aging (time frame: 12 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Feb 2023.