Smoking CessationNCT05075213
QuitBet Phase II: A Digital Social Game That Pays You to Stop Smoking
A study testing contingency management (deposit contract), leaderboard and social feed and smoking cessation resource list in people with Smoking Cessation, run by WayBetter, Inc. at 1 site in United States.
Trial summary
This study is a randomized controlled trial (RCT) of QuitBet, a digital contingency management program for smoking cessation. QuitBet combines social gaming elements with participant-funded financial incentives in the form of a deposit contract. Read more about this study
- Who is it for?
- Ages 21 years and older
- Conditions the study is for
- Smoking Cessation
- What is being tested?
- contingency management (deposit contract), leaderboard and social feed and smoking cessation resource list
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 245 participants
- Where
- 1 siteUnited States
- Study dates
- 1 Nov 2021to 27 Jul 2024
- Phase
- Interventional
- Are there results?
- Yes, posted in the registrySummary in the doctors' view
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 21 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Sufficient English fluency to complete study procedures
- At least 21 years of age
- U.S. resident of any state
- currently smokes at least 5 cigarettes per day
- has an email address
- has a mailing address at which they can receive packages
Show all 9Show fewer
- owns an Internet-connected Apple iPhone or Android smartphone that is compatible with QuitBet
- willing to deposit $30 via PayPal or a credit card
- willing to receive financial incentives earned during QuitBet via PayPal or in a paper check sent by mail
Who cannot join
None listed.
Trial locations and contacts
1 site in 1 country.
About this study
This study is a randomized controlled trial (RCT) of QuitBet, a digital contingency management program for smoking cessation. QuitBet combines social gaming elements with participant-funded financial incentives in the form of a deposit contract. QuitBet "players" deposit (called the "bet") a specified amount of their own money into the game's "pot." All "winners" who achieve the game's goal split the pot equally, such that their bet is fully refunded plus they receive extra money from the forfeited bets of players who did not meet the goal. Participants (N = 550) will be randomly assigned to QuitBet or QuitBet-NS (deposit contract only, no social elements). All participants will be offered a second game after their first game (up to 8 weeks total game duration) and will be asked to complete a survey after each game and at 1 and 4 months after the end of the second game (3 and 6 months after the start of their first game). The study will compare QuitBet vs. QuitBet-NS on smoking behavior outcomes and examine potential mediators of outcomes such as motivation, engagement, and satisfaction.
- Conditions
- Smoking Cessation
- Being tested
- contingency management (deposit contract), leaderboard and social feed, smoking cessation resource list
- Medical subject headings
- Smoking Cessation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
contingency management (deposit contract)Behavioural
Participants will deposit $30 of their own money to play QuitBet. Participants will submit a CO test once per day between the hours of noon and 11:59pm. Participants whose CO test is 6ppm or lower (indicating no smoking) on at least 24 of 26 days between day 3-28 of the game will be declared winners and split the pot of deposited money. Participants who submit at least 21 CO tests, regardless of the result, will be entered into a raffle to win a prize worth $75.
leaderboard and social feedBehavioural
Participants will have access to a discussion board on which participants can post and respond to messages to each other. Also, a game host will post educational information about smoking cessation and serve as a discussion moderator.
smoking cessation resource listBehavioural
Participants will have access to a list of smoking cessation resources
| Study group | Role | What they receive |
|---|---|---|
| QuitBet | Experimental | QuitBet is a quit smoking game delivered via a smartphone application that lasts 28 days and includes contingency management in the form of a deposit contract, integrated exhaled breath carbon monoxide (CO) testing, a social feed on which "players" can post and respond to messages, and a "leaderboard" that displays players' status (i.e., whether they are still eligible to win). A game host will post educational information about smoking cessation and serve as a discussion moderator. Participants will deposit ("bet") $30 of their own money at the start of the game. Participants who submit a CO test that is 6ppm or lower (indicating no smoking) on at least 24 of the 26 days between day 3-28 will be declared winners and will split the pot of money that was deposited. All participants who submit at least 21 CO tests during the 28 day game, regardless of the CO test result, will be entered into a lottery to win a prize worth $75. Receives: Behavioral: contingency management (deposit contract); Behavioral: leaderboard and social feed |
| QuitBet-NS (no social elements) | Active comparator | QuitBet-NS will include the deposit contract and integrated CO testing with identical rules to QuitBet for being a winner, the $75 raffle for submitting at least 21 CO tests, a display of the participant's daily CO test results that is updated in real time, and a game feed on which only the game host has the ability to post. Players will not be able to post on this feed or respond to the host's posts. At the beginning of the game, the host will post limited information, including a list of smoking cessation resources. QuitBet-NS will NOT include the social feed, leaderboard, or any other social features. Receives: Behavioral: contingency management (deposit contract); Behavioral: smoking cessation resource list |
What is being measured
The primary outcome is the main question the study is designed to answer.
Number of Participants Who Reported no Cigarette Smoking During the Past 7 Days
At 6 month follow-up, participant reported no smoking during the past 7 days (survey question: "Have you smoked a cigarette, even just a puff, during the past 7 days?" with answer choices of "yes" or "no" - participant responded "no").
Measured: 6 months after the start date of their first QuitBet game
Secondary outcomes (3)
Number of Participants Who Choose to Play a Second Game
Number of participants who chose to play a second QuitBet game
Measured: 4 weeks after the start date of their first QuitBet game (end of game), when they were given the option to join a second game
Cigarettes Per Day During the Past 7 Days
At 6 month follow up, the number of cigarettes the participant reported smoking during the previous 7 days (survey respondents only).
In the 6 month follow-up survey, participants were first asked "Have you smoked a cigarette, even just a puff, during the past 7 days?" (yes/no answer choice). Participants who answered "no" were counted as smoking 0 cigarettes in this analysis. Participants who answered "yes" were then asked to report how many cigarettes they smoked on each day during the past week (day 1 being this day last week, day 2, day 3, day 4, day 5, day 6, day 7 being yesterday). The average of the 7 days was used in this analysis.
Measured: 6 months after the start of their first QuitBet game
Number of Participants Who Used Smoking Cessation Medication
Number of participants who reported use of any smoking cessation medication (including any form of nicotine replacement therapy, buproprion, or varencline) at any time during their participation in the study, from the start of their first QuitBet game until the last follow-up 6 months later
Measured: 6 month period beginning with the start of their first QuitBet game
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted12 Oct 2021
- Study start1 Nov 2021
- Primary completion27 Jul 2024
- Study completion27 Jul 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Posted resultsParticipant flow, outcome measures and adverse events reported by the sponsor.
- Other trials for Smoking CessationStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 245 participants (actual)
Sponsor and investigators
- Lead sponsor
- WayBetter, Inc.
- Sponsor type
- Industry (pharma, biotech, devices)
- Collaborators
- Hennepin Healthcare Research Institute
- Responsible party
- Sponsor
- Investigators
- Jamie Rosen, Principal investigator, WayBetter, Inc.
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05075213
- Sponsor's protocol ID
- QuitBet Phase II
- Status last verified
- Feb 2026
- First submitted
- 17 Sep 2021
- Last updated
- 27 Feb 2026
- Results posted
- Yes, on ClinicalTrials.gov
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 27 Feb 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- QuitBet Phase II: A Digital Social Game That Pays You to Stop Smoking
- ClinicalTrials.gov ID
- NCT05075213
- Acronym / sponsor ID
- QuitBet Phase II
- Conditions
- Smoking Cessation
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 245 participants (actual)
- Lead sponsor
- WayBetter, Inc.Industry (pharma, biotech, devices)
- Collaborators
- Hennepin Healthcare Research Institute
- Study start
- 1 Nov 2021 (actual)
- Primary completion
- 27 Jul 2024 (actual)
- Study completion
- 27 Jul 2024 (actual)
- First posted
- 12 Oct 2021 (actual)
- Results
- Posted 27 Feb 2026
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study is a randomized controlled trial (RCT) of QuitBet, a digital contingency management program for smoking cessation. QuitBet combines social gaming elements with participant-funded financial incentives in the form of a deposit contract. QuitBet "players" deposit (called the "bet") a specified amount of their own money into the game's "pot." All "winners" who achieve the game's goal split the pot equally, such that their bet is fully refunded plus they receive extra money from the forfeited bets of players who did not meet the goal. Participants (N = 550) will be randomly assigned to QuitBet or QuitBet-NS (deposit contract only, no social elements). All participants will be offered a second game after their first game (up to 8 weeks total game duration) and will be asked to complete a survey after each game and at 1 and 4 months after the end of the second game (3 and 6 months after the start of their first game). The study will compare QuitBet vs. QuitBet-NS on smoking behavior outcomes and examine potential mediators of outcomes such as motivation, engagement, and satisfaction.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| QuitBet | Experimental | Behavioral: contingency management (deposit contract), Behavioral: leaderboard and social feedQuitBet is a quit smoking game delivered via a smartphone application that lasts 28 days and includes contingency management in the form of a deposit contract, integrated exhaled breath carbon monoxide (CO) testing, a social feed on which "players" can post and respond to messages, and a "leaderboard" that displays players' status (i.e., whether they are still eligible to win). A game host will post educational information about smoking cessation and serve as a discussion moderator. Participants will deposit ("bet") $30 of their own money at the start of the game. Participants who submit a CO test that is 6ppm or lower (indicating no smoking) on at least 24 of the 26 days between day 3-28 will be declared winners and will split the pot of money that was deposited. All participants who submit at least 21 CO tests during the 28 day game, regardless of the CO test result, will be entered into a lottery to win a prize worth $75. |
| QuitBet-NS (no social elements) | Active comparator | Behavioral: contingency management (deposit contract), Behavioral: smoking cessation resource listQuitBet-NS will include the deposit contract and integrated CO testing with identical rules to QuitBet for being a winner, the $75 raffle for submitting at least 21 CO tests, a display of the participant's daily CO test results that is updated in real time, and a game feed on which only the game host has the ability to post. Players will not be able to post on this feed or respond to the host's posts. At the beginning of the game, the host will post limited information, including a list of smoking cessation resources. QuitBet-NS will NOT include the social feed, leaderboard, or any other social features. |
Who may qualify
- Ages
- 21 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (9 listed)
- Sufficient English fluency to complete study procedures
- At least 21 years of age
- U.S. resident of any state
- currently smokes at least 5 cigarettes per day
- has an email address
Key exclusion criteria (0 listed)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| contingency management (deposit contract)Participants will deposit $30 of their own money to play QuitBet. Participants will submit a CO test once per day between the hours of noon and 11:59pm. Participants whose CO test is 6ppm or lower (indicating no smoking) on at least 24 of 26 days between day 3-28 of the game will be declared winners and split the pot of deposited money. Participants who submit at least 21 CO tests, regardless of the result, will be entered into a raffle to win a prize worth $75. | Behavioural | QuitBet, QuitBet-NS (no social elements) |
| leaderboard and social feedParticipants will have access to a discussion board on which participants can post and respond to messages to each other. Also, a game host will post educational information about smoking cessation and serve as a discussion moderator. | Behavioural | QuitBet |
| smoking cessation resource listParticipants will have access to a list of smoking cessation resources | Behavioural | QuitBet-NS (no social elements) |
Primary outcome
Number of Participants Who Reported no Cigarette Smoking During the Past 7 Days
Time frame: 6 months after the start date of their first QuitBet game
At 6 month follow-up, participant reported no smoking during the past 7 days (survey question: "Have you smoked a cigarette, even just a puff, during the past 7 days?" with answer choices of "yes" or "no" - participant responded "no").
3 secondary outcomes
Number of Participants Who Choose to Play a Second Game
Time frame: 4 weeks after the start date of their first QuitBet game (end of game), when they were given the option to join a second game
Cigarettes Per Day During the Past 7 Days
Time frame: 6 months after the start of their first QuitBet game
Number of Participants Who Used Smoking Cessation Medication
Time frame: 6 month period beginning with the start of their first QuitBet game
Results and safety
Loading the posted results from ClinicalTrials.gov…
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 27 Feb 2026.
- Posted resultsParticipant flow, baseline, all outcome measures and adverse events.
- Individual participant dataSharing planned: Undecided
Related trials for Smoking Cessation
Enrolling by invitationObservational study
Using Smartwatches to Monitor Smoking in Real-life Situations
Smoking
Not yet recruitingObservational study
PROMETHEE: A Shared Interregional Tele-Tobacco Cessation Platform Embedded Within the IMPULSION Lung Cancer Screening Program
Smoking Cessation, Lung Cancer Screening
Not yet recruiting
Impacto 2.0: Mobile Smoking Cessation Across Texas
Cigarette Smoking, Smoking Cessation
Not yet recruiting
Smoking Cessation Program for Lao People With HIV
Smoking Cessation, HIV
RecruitingPhase 3
Studying NMDA and Sigma-1 in Smoking Cessation Treatment (SUMMIT)
Smoking Cessation
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Jamie Rosen principal investigator
WayBetter, Inc.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing contingency management (deposit contract), leaderboard and social feed and smoking cessation resource list in people with Smoking Cessation, run by WayBetter, Inc. at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 9 inclusion and 0 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 27 Feb 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Yes. Results are posted in the registry (first posted 27 Feb 2026). A summary is in the For doctors view, and the full results are on ClinicalTrials.gov.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Number of Participants Who Reported no Cigarette Smoking During the Past 7 Days (time frame: 6 months after the start date of their first QuitBet game). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 27 Feb 2026.