Opioid Use DisorderNCT05127707
Strategies to Reduce Addiction Stigma Among Health Professionals
A study testing Words Matter - Visual Campaign, Words Matter - Visual Campaign & Narrative Vignette (Messenger: Person with Opioid Use Disorder) Experimental: Words Matter - Visual Campaign & Narrative Vignette (Messenger: Clinician) and Words Matter - Visual Campaign & Narrative Vignette (Messenger: Clinician) in people with Opioid Use Disorder and Substance Use Disorders, run by Johns Hopkins Bloomberg School of Public Health at 1 site in United States.
Trial summary
The aim of this study was to evaluate the effects of exposure to stigma reduction message frames communicated by visual campaigns and narrative vignettes among a national sample of health professionals. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Opioid Use Disorder, Substance Use Disorders, Stigma, Social
- What is being tested?
- Words Matter - Visual Campaign, Words Matter - Visual Campaign & Narrative Vignette (Messenger: Person with Opioid Use Disorder) Experimental: Words Matter - Visual Campaign & Narrative Vignette (Messenger: Clinician) and Words Matter - Visual Campaign & Narrative Vignette (Messenger: Clinician)
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 1,842 participants
- Where
- 1 siteUnited States
- Study dates
- 13 Nov 2020to 30 Nov 2020
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- employed as health professional in the United States, including clinicians (e.g., physicians, nurses, physician assistants, pharmacists, and optometrists), technicians and technologists (e.g., laboratory technologist or technician, emergency medical technician, paramedic, licensed practical or licensed vocational nurse, medical records or health information technician, etc.), health aids and assistants (e.g., nursing aide, home health aide, medical assistant, pharmacy aide, phlebotomist, etc.)
- participant in existing web-based survey panel (IPSOS's KnowledgeNetworks panel and partner opt-in panel)
Who cannot join
- not employed in health profession
- not able to complete experiment and survey in English
Trial locations and contacts
1 site in 1 country.
United States1 site
Johns Hopkins Bloomberg School of Public Health
Baltimore, Maryland, 21205
About this study
Official title: Effect of Exposure to Visual Campaigns and Narrative Vignettes on Addiction Stigma Among Health Professionals: A Randomized Experiment
The aim of this study was to evaluate the effects of exposure to stigma reduction message frames communicated by visual campaigns and narrative vignettes among a national sample of health professionals.
Read the detailed description
This randomized experiment evaluated the impact of exposure to message frames communicating the importance of non-stigmatizing language regarding addiction and the effectiveness of medication treatment for opioid use disorder delivered through a visual campaign alone or through a visual campaign in addition to a narrative vignette from the perspective of one of three messengers (a person with opioid use disorder, a clinician, or a health system leader) on attitudes toward people with opioid use disorder and medications for treating opioid use disorder among a national sample of health professionals.
- Conditions
- Opioid Use Disorder, Substance Use Disorders, Stigma, Social
- Being tested
- Words Matter - Visual Campaign, Words Matter - Visual Campaign & Narrative Vignette (Messenger: Person with Opioid Use Disorder) Experimental: Words Matter - Visual Campaign & Narrative Vignette (Messenger: Clinician), Words Matter - Visual Campaign & Narrative Vignette (Messenger: Clinician), Words Matter - Visual Campaign & Narrative Vignette (Messenger: Health System Administrator), Medication Treatment for Opioid Use Disorder Works - Visual Campaign
- Medical subject headings
- Opioid-Related Disorders, Substance-Related Disorders, Social Stigma
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Words Matter - Visual CampaignBehavioural
Visual campaign emphasizing the importance of using non-stigmatizing language related to substance use and opioid use disorder in clinical settings.
Words Matter - Visual Campaign & Narrative Vignette (Messenger: Person with Opioid Use Disorder) Experimental: Words Matter - Visual Campaign & Narrative Vignette (Messenger: Clinician)Behavioural
Visual campaign emphasizing the importance of using non-stigmatizing language related to substance use and opioid use disorder in clinical settings combined with a narrative vignette told from the perspective of a person with opioid use disorder
Words Matter - Visual Campaign & Narrative Vignette (Messenger: Clinician)Behavioural
Visual campaign emphasizing the importance of using non-stigmatizing language related to substance use and opioid use disorder in clinical settings combined with a narrative vignette told from the perspective of a clinician working with patients with opioid use disorder
Words Matter - Visual Campaign & Narrative Vignette (Messenger: Health System Administrator)Behavioural
Visual campaign emphasizing the importance of using non-stigmatizing language related to substance use and opioid use disorder in clinical settings combined with a narrative vignette told from the perspective of a health system administrator/leader
Medication Treatment for Opioid Use Disorder Works - Visual CampaignBehavioural
Visual campaign emphasizing the effectiveness and value of medications to treat opioid use disorder in saving lives
Medication Treatment for Opioid Use Disorder Works - Visual Campaign & Narrative Vignette (Messenger: Person with Opioid Use Disorder)Behavioural
Visual campaign emphasizing the effectiveness and value of medications to treat opioid use disorder in saving lives combined with a narrative vignette told from the perspective of a person with opioid use disorder
Medication Treatment for Opioid Use Disorder Works - Visual Campaign & Narrative Vignette (Messenger: Clinician)Behavioural
Visual campaign emphasizing the effectiveness and value of medications to treat opioid use disorder in saving lives combined with a narrative vignette told from the perspective of a clinician who treats people with opioid use disorder
Medication Treatment for Opioid Use Disorder Works - Visual Campaign & Narrative Vignette (Messenger: Health System Administrator)Behavioural
Visual campaign emphasizing the effectiveness and value of medications to treat opioid use disorder in saving lives combined with a narrative vignette told from the perspective of a health system administrator/leader
| Study group | Role | What they receive |
|---|---|---|
| No exposure control group | No intervention | This group was not exposed to any message frame. |
| Words Matter - Visual Campaign | Experimental | Participants randomized to this arm were exposed to a visual campaign communicating the importance of use of non-stigmatizing language regarding substance use disorder and opioid use disorder in clinical settings. Receives: Behavioral: Words Matter - Visual Campaign |
| Words Matter - Visual Campaign & Narrative Vignette (Messenger: Person with Opioid Use Disorder) | Experimental | Participants randomized to this arm were exposed to a visual campaign communicating the importance of use of non-stigmatizing language regarding substance use disorder and opioid use disorder in clinical settings and a narrative vignette told from the perspective of a person with opioid use disorder. Receives: Behavioral: Words Matter - Visual Campaign & Narrative Vignette (Messenger: Person with Opioid Use Disorder) Experimental: Words Matter - Visual Campaign & Narrative Vignette (Messenger: Clinician) |
| Words Matter - Visual Campaign & Narrative Vignette (Messenger: Clinician) | Experimental | Participants randomized to this arm were exposed to a visual campaign communicating the importance of use of non-stigmatizing language regarding substance use disorder and opioid use disorder in clinical settings and a narrative vignette told from the perspective of a clinician. Receives: Behavioral: Words Matter - Visual Campaign & Narrative Vignette (Messenger: Clinician) |
| Words Matter - Visual Campaign & Narrative Vignette (Messenger: Health System Administrator) | Experimental | Participants randomized to this arm were exposed to a visual campaign communicating the importance of use of non-stigmatizing language regarding substance use disorder and opioid use disorder in clinical settings and a narrative vignette told from the perspective of a health system administrator/leader. Receives: Behavioral: Words Matter - Visual Campaign & Narrative Vignette (Messenger: Health System Administrator) |
| Medication Treatment Works - Visual Campaign | Experimental | Participants randomized to this arm were exposed to a visual campaign communicating the effectiveness of medications for treating opioid use disorder in saving lives. Receives: Behavioral: Medication Treatment for Opioid Use Disorder Works - Visual Campaign |
| Medication Treatment Works - Visual Campaign & Narrative Vignette (Person with OUD) | Experimental | Participants randomized to this arm were exposed to a visual campaign communicating the effectiveness of medications for treating opioid use disorder in saving lives and a narrative vignette told from the perspective of a person with opioid use disorder. Receives: Behavioral: Medication Treatment for Opioid Use Disorder Works - Visual Campaign & Narrative Vignette (Messenger: Person with Opioid Use Disorder) |
| Medication Treatment Works - Visual Campaign & Narrative Vignette (Clinician) | Experimental | Participants randomized to this arm were exposed to a visual campaign communicating the effectiveness of medications for treating opioid use disorder in saving lives and a narrative vignette told from the perspective of a clinician. Receives: Behavioral: Medication Treatment for Opioid Use Disorder Works - Visual Campaign & Narrative Vignette (Messenger: Clinician) |
| Medication Treatment Works - Visual Campaign & Narrative Vignette (Health System Administrator) | Experimental | Participants randomized to this arm were exposed to a visual campaign communicating the effectiveness of medications for treating opioid use disorder in saving lives and a narrative vignette told from the perspective of a health system administrator/leader. Receives: Behavioral: Medication Treatment for Opioid Use Disorder Works - Visual Campaign & Narrative Vignette (Messenger: Health System Administrator) |
What is being measured
The primary outcome is the main question the study is designed to answer.
Rating of willingness to have person with opioid use disorder marry into their family
Item from the Social Distance Scale that measures one element of stigma (desire for social distance). Measured on 5-point Likert scale with 5 indicating greater unwillingness and 1 indicating greater willingness to have a person with opioid use disorder marry into the family. Measured via survey questionnaire.
Measured: Measured immediately post-exposure to message frame intervention
Rating of willingness to have person with opioid use disorder as a neighbor
Item from the Social Distance Scale that measures one element of stigma (desire for social distance). Measured on 5-point Likert scale with 5 indicating greater unwillingness and 1 indicating greater willingness to have a person with opioid use disorder as a neighbor. Measured via survey questionnaire.
Measured: Measured immediately post-exposure to message frame intervention
Rating of agreement that opioid use disorder is a medical condition
Rating of agreement with statement "Opioid use disorder is a chronic medical condition like diabetes mellitus" on 5-point Likert scale with 5 indicating strong disagreement and 1 indicating strong agreement. Measured via survey questionnaire.
Measured: Measured immediately post-exposure to message frame intervention
Rating of agreement that individuals with opioid use disorder are to blame
Rating of agreement with statement "Individuals with opioid use disorder only have themselves to blame for their problem" on 5-point Likert scale with 5 indicating strong disagreement and 1 indicating strong agreement. Measured via survey questionnaire.
Measured: Measured immediately post-exposure to message frame intervention
Rating of support for increasing government spending on opioid use disorder treatment
Rating of support for increasing government spending on treatment of opioid use disorder with 5 indicating strongly favoring and 1 indicating strongly opposing. Measured via survey questionnaire.
Measured: Measured immediately post-exposure to message frame intervention
Feeling thermometer measure of warmth toward people with opioid use disorder
Rating of warmth felt toward people with opioid use disorder with 0 indicating extremely cold and 100 indicating extremely warm. Measured via survey questionnaire.
Measured: Measured immediately post-exposure to message frame intervention
Secondary outcomes (17)
Stigmatizing Language - Addict
Rating of agreement that term "addict" appropriate in a clinical care setting with 1 indicating strongly agree (that term is appropriate) and 5 indicating strongly disagree (that term is appropriate). Measured via survey questionnaire.
Measured: Measured immediately post-exposure to message frame intervention
Stigmatizing Language - Substance abuse
Rating of agreement that term "substance abuse" appropriate in a clinical care setting with 1 indicating strongly agree (that term is appropriate) and 5 indicating strongly disagree (that term is appropriate). Measured via survey questionnaire.
Measured: Measured immediately post-exposure to message frame intervention
Stigmatizing Language - dirty
Rating of agreement that term "'dirty' in reference to the result from a drug test" appropriate in a clinical care setting with 1 indicating strongly agree (that term is appropriate) and 5 indicating strongly disagree (that term is appropriate). Measured via survey questionnaire.
Measured: Measured immediately post-exposure to message frame intervention
Stigmatizing Language - clean
Rating of agreement that term "'clean' in reference to the result from a drug test" appropriate in a clinical care setting with 1 indicating strongly agree (that term is appropriate) and 5 indicating strongly disagree (that term is appropriate). Measured via survey questionnaire.
Measured: Measured immediately post-exposure to message frame intervention
Stigmatizing Language - addicted baby
Rating of agreement that term "addicted baby" appropriate in a clinical care setting with 1 indicating strongly agree (that term is appropriate) and 5 indicating strongly disagree (that term is appropriate). Measured via survey questionnaire.
Measured: Measured immediately post-exposure to message frame intervention
Stigmatizing Language - person with substance use disorder
Rating of agreement that term "person with substance use disorder" appropriate in a clinical care setting with 1 indicating strongly agree (that term is appropriate) and 5 indicating strongly disagree (that term is appropriate). Measured via survey questionnaire.
Measured: Measured immediately post-exposure to message frame intervention
Stigmatizing Language - substance use
Rating of agreement that term "substance use" appropriate in a clinical care setting with 1 indicating strongly agree (that term is appropriate) and 5 indicating strongly disagree (that term is appropriate). Measured via survey questionnaire.
Measured: Measured immediately post-exposure to message frame intervention
Stigmatizing Language - negative test result
Rating of agreement that term "negative test result" appropriate in a clinical care setting with 1 indicating strongly agree (that term is appropriate) and 5 indicating strongly disagree (that term is appropriate). Measured via survey questionnaire.
Measured: Measured immediately post-exposure to message frame intervention
Stigmatizing Language - positive test result
Rating of agreement that term "positive test result" appropriate in a clinical care setting with 1 indicating strongly agree (that term is appropriate) and 5 indicating strongly disagree (that term is appropriate). Measured via survey questionnaire.
Measured: Measured immediately post-exposure to message frame intervention
Stigmatizing Language - baby born with neonatal opioid withdrawal syndrome
Rating of agreement that term "baby born with neonatal opioid withdrawal syndrome" appropriate in a clinical care setting with 1 indicating strongly agree (that term is appropriate) and 5 indicating strongly disagree (that term is appropriate). Measured via survey questionnaire.
Measured: Measured immediately post-exposure to message frame intervention
Willingness to sign pledge committing to using non-stigmatizing language
Binary (yes/no) measure of whether participant is willing to sign a pledge committing to using non-stigmatizing language related to substance use disorder in clinical settings. Measured via survey questionnaire.
Measured: Measured immediately post-exposure to message frame intervention
Perception of opioid use disorder treatment effectiveness
Participant perception of whether there is a treatment for opioid use disorder that is effective for a long period of time (three close-ended response options: yes, there is a treatment; no, there isn't such a treatment; don't know). Measured via survey questionnaire.
Measured: Measured immediately post-exposure to message frame intervention
Rating of willingness to have person taking medication marry into their family
Rating of willingness to have person taking medication to treat opioid use disorder marry into family. Item from the Social Distance Scale that measures one element of stigma (desire for social distance). Measured on 5-point Likert scale with 5 indicating greater unwillingness and 1 indicating greater willingness to have a person taking medication to treat opioid use disorder marry into the family. Measured via survey questionnaire.
Measured: Measured immediately post-exposure to message frame intervention
Rating of willingness to have person taking medication marry as a neighbor
Rating of willingness to have person taking medication to treat opioid use disorder as a neighbor. Item from the Social Distance Scale that measures one element of stigma (desire for social distance). Measured on 5-point Likert scale with 5 indicating greater unwillingness and 1 indicating greater willingness to have a person taking medication to treat opioid use disorder as a neighbor. Measured via survey questionnaire.
Measured: Measured immediately post-exposure to message frame intervention
Rating of strength/weakness of person taking medication
Rating of strength/weakness of person taking medication to treat opioid use disorder on 5-point Likert scale with 5 indicating strong and 1 indicating weak. This is a semantic differential measure. Measured via survey questionnaire.
Measured: Measured immediately post-exposure to message frame intervention
Rating of agreement that recovery is possible
Rating of agreement with statement "Most people with opioid use disorder will, with medication treatment, get well and return to productive lives" on a 5-point Likert scale with 5 indicating strongly disagree and 1 indicating strongly agree. Measured via survey questionnaire.
Measured: Measured immediately post-exposure to message frame intervention
Feeling thermometer measure of warmth toward people taking medication
Rating of warmth felt toward people taking medication to treat opioid use disorder with 0 indicating extremely cold and 100 indicating extremely warm. Measured via survey questionnaire.
Measured: Measured immediately post-exposure to message frame intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 Nov 2021
- Study start13 Nov 2020
- Primary completion30 Nov 2020
- Study completion30 Nov 2020
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Opioid Use DisorderStudies of the same condition, open and under way.
- More trials run by Johns Hopkins Bloomberg School of Public HealthThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 1,842 participants (actual)
Sponsor and investigators
- Lead sponsor
- Johns Hopkins Bloomberg School of Public Health
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Alene Kennedy-Hendricks, PhD, Principal investigator, Johns Hopkins Bloomberg School of Public Health
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05127707
- Sponsor's protocol ID
- IRB14743
- Status last verified
- Nov 2021
- First submitted
- 28 Oct 2021
- Last updated
- 19 Nov 2021
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Kennedy-Hendricks A, McGinty EE, Summers A, Krenn S, Fingerhood MI, Barry CL. Effect of Exposure to Visual Campaigns and Narrative Vignettes on Addiction Stigma Among Health Care Professionals: A Randomized Clinical Trial. JAMA Netw Open. 2022 Feb 1;5(2):e2146971. doi: 10.1001/jamanetworkopen.2021.46971.
PubMed 35119460
Study at a glance
From the registry record, last updated by the sponsor on 19 Nov 2021. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Exposure to Visual Campaigns and Narrative Vignettes on Addiction Stigma Among Health Professionals: A Randomized Experiment
- ClinicalTrials.gov ID
- NCT05127707
- Acronym / sponsor ID
- IRB14743
- Conditions
- Opioid Use Disorder, Substance Use Disorders, Stigma, Social
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 1,842 participants (actual)
- Lead sponsor
- Johns Hopkins Bloomberg School of Public HealthUniversity, hospital or other
- Study start
- 13 Nov 2020 (actual)
- Primary completion
- 30 Nov 2020 (actual)
- Study completion
- 30 Nov 2020 (actual)
- First posted
- 19 Nov 2021 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this study was to evaluate the effects of exposure to stigma reduction message frames communicated by visual campaigns and narrative vignettes among a national sample of health professionals.
Detailed description
This randomized experiment evaluated the impact of exposure to message frames communicating the importance of non-stigmatizing language regarding addiction and the effectiveness of medication treatment for opioid use disorder delivered through a visual campaign alone or through a visual campaign in addition to a narrative vignette from the perspective of one of three messengers (a person with opioid use disorder, a clinician, or a health system leader) on attitudes toward people with opioid use disorder and medications for treating opioid use disorder among a national sample of health professionals.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 9
| Arm | Type | Receives |
|---|---|---|
| No exposure control group | No intervention | –This group was not exposed to any message frame. |
| Words Matter - Visual Campaign | Experimental | Behavioral: Words Matter - Visual CampaignParticipants randomized to this arm were exposed to a visual campaign communicating the importance of use of non-stigmatizing language regarding substance use disorder and opioid use disorder in clinical settings. |
| Words Matter - Visual Campaign & Narrative Vignette (Messenger: Person with Opioid Use Disorder) | Experimental | Behavioral: Words Matter - Visual Campaign & Narrative Vignette (Messenger: Person with Opioid Use Disorder) Experimental: Words Matter - Visual Campaign & Narrative Vignette (Messenger: Clinician)Participants randomized to this arm were exposed to a visual campaign communicating the importance of use of non-stigmatizing language regarding substance use disorder and opioid use disorder in clinical settings and a narrative vignette told from the perspective of a person with opioid use disorder. |
| Words Matter - Visual Campaign & Narrative Vignette (Messenger: Clinician) | Experimental | Behavioral: Words Matter - Visual Campaign & Narrative Vignette (Messenger: Clinician)Participants randomized to this arm were exposed to a visual campaign communicating the importance of use of non-stigmatizing language regarding substance use disorder and opioid use disorder in clinical settings and a narrative vignette told from the perspective of a clinician. |
| Words Matter - Visual Campaign & Narrative Vignette (Messenger: Health System Administrator) | Experimental | Behavioral: Words Matter - Visual Campaign & Narrative Vignette (Messenger: Health System Administrator)Participants randomized to this arm were exposed to a visual campaign communicating the importance of use of non-stigmatizing language regarding substance use disorder and opioid use disorder in clinical settings and a narrative vignette told from the perspective of a health system administrator/leader. |
| Medication Treatment Works - Visual Campaign | Experimental | Behavioral: Medication Treatment for Opioid Use Disorder Works - Visual CampaignParticipants randomized to this arm were exposed to a visual campaign communicating the effectiveness of medications for treating opioid use disorder in saving lives. |
| Medication Treatment Works - Visual Campaign & Narrative Vignette (Person with OUD) | Experimental | Behavioral: Medication Treatment for Opioid Use Disorder Works - Visual Campaign & Narrative Vignette (Messenger: Person with Opioid Use Disorder)Participants randomized to this arm were exposed to a visual campaign communicating the effectiveness of medications for treating opioid use disorder in saving lives and a narrative vignette told from the perspective of a person with opioid use disorder. |
| Medication Treatment Works - Visual Campaign & Narrative Vignette (Clinician) | Experimental | Behavioral: Medication Treatment for Opioid Use Disorder Works - Visual Campaign & Narrative Vignette (Messenger: Clinician)Participants randomized to this arm were exposed to a visual campaign communicating the effectiveness of medications for treating opioid use disorder in saving lives and a narrative vignette told from the perspective of a clinician. |
| Medication Treatment Works - Visual Campaign & Narrative Vignette (Health System Administrator) | Experimental | Behavioral: Medication Treatment for Opioid Use Disorder Works - Visual Campaign & Narrative Vignette (Messenger: Health System Administrator)Participants randomized to this arm were exposed to a visual campaign communicating the effectiveness of medications for treating opioid use disorder in saving lives and a narrative vignette told from the perspective of a health system administrator/leader. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (2 listed)
- employed as health professional in the United States, including clinicians (e.g., physicians, nurses, physician assistants, pharmacists, and optometrists), technicians and technologists (e.g., laboratory technologist or technician, emergency medical technician, paramedic, licensed practical or licensed vocational nurse, medical records or health information technician, etc.), health aids and assistants (e.g., nursing aide, home health aide, medical assistant, pharmacy aide, phlebotomist, etc.)
- participant in existing web-based survey panel (IPSOS's KnowledgeNetworks panel and partner opt-in panel)
Key exclusion criteria (2 listed)
- not employed in health profession
- not able to complete experiment and survey in English
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Words Matter - Visual CampaignVisual campaign emphasizing the importance of using non-stigmatizing language related to substance use and opioid use disorder in clinical settings. | Behavioural | Words Matter - Visual Campaign |
| Words Matter - Visual Campaign & Narrative Vignette (Messenger: Person with Opioid Use Disorder) Experimental: Words Matter - Visual Campaign & Narrative Vignette (Messenger: Clinician)Visual campaign emphasizing the importance of using non-stigmatizing language related to substance use and opioid use disorder in clinical settings combined with a narrative vignette told from the perspective of a person with opioid use disorder | Behavioural | Words Matter - Visual Campaign & Narrative Vignette (Messenger: Person with Opioid Use Disorder) |
| Words Matter - Visual Campaign & Narrative Vignette (Messenger: Clinician)Visual campaign emphasizing the importance of using non-stigmatizing language related to substance use and opioid use disorder in clinical settings combined with a narrative vignette told from the perspective of a clinician working with patients with opioid use disorder | Behavioural | Words Matter - Visual Campaign & Narrative Vignette (Messenger: Clinician) |
| Words Matter - Visual Campaign & Narrative Vignette (Messenger: Health System Administrator)Visual campaign emphasizing the importance of using non-stigmatizing language related to substance use and opioid use disorder in clinical settings combined with a narrative vignette told from the perspective of a health system administrator/leader | Behavioural | Words Matter - Visual Campaign & Narrative Vignette (Messenger: Health System Administrator) |
| Medication Treatment for Opioid Use Disorder Works - Visual CampaignVisual campaign emphasizing the effectiveness and value of medications to treat opioid use disorder in saving lives | Behavioural | Medication Treatment Works - Visual Campaign |
| Medication Treatment for Opioid Use Disorder Works - Visual Campaign & Narrative Vignette (Messenger: Person with Opioid Use Disorder)Visual campaign emphasizing the effectiveness and value of medications to treat opioid use disorder in saving lives combined with a narrative vignette told from the perspective of a person with opioid use disorder | Behavioural | Medication Treatment Works - Visual Campaign & Narrative Vignette (Person with OUD) |
| Medication Treatment for Opioid Use Disorder Works - Visual Campaign & Narrative Vignette (Messenger: Clinician)Visual campaign emphasizing the effectiveness and value of medications to treat opioid use disorder in saving lives combined with a narrative vignette told from the perspective of a clinician who treats people with opioid use disorder | Behavioural | Medication Treatment Works - Visual Campaign & Narrative Vignette (Clinician) |
| Medication Treatment for Opioid Use Disorder Works - Visual Campaign & Narrative Vignette (Messenger: Health System Administrator)Visual campaign emphasizing the effectiveness and value of medications to treat opioid use disorder in saving lives combined with a narrative vignette told from the perspective of a health system administrator/leader | Behavioural | Medication Treatment Works - Visual Campaign & Narrative Vignette (Health System Administrator) |
Primary outcome
Rating of willingness to have person with opioid use disorder marry into their family
Time frame: Measured immediately post-exposure to message frame intervention
Item from the Social Distance Scale that measures one element of stigma (desire for social distance). Measured on 5-point Likert scale with 5 indicating greater unwillingness and 1 indicating greater willingness to have a person with opioid use disorder marry into the family. Measured via survey questionnaire.
Rating of willingness to have person with opioid use disorder as a neighbor
Time frame: Measured immediately post-exposure to message frame intervention
Item from the Social Distance Scale that measures one element of stigma (desire for social distance). Measured on 5-point Likert scale with 5 indicating greater unwillingness and 1 indicating greater willingness to have a person with opioid use disorder as a neighbor. Measured via survey questionnaire.
Rating of agreement that opioid use disorder is a medical condition
Time frame: Measured immediately post-exposure to message frame intervention
Rating of agreement with statement "Opioid use disorder is a chronic medical condition like diabetes mellitus" on 5-point Likert scale with 5 indicating strong disagreement and 1 indicating strong agreement. Measured via survey questionnaire.
Rating of agreement that individuals with opioid use disorder are to blame
Time frame: Measured immediately post-exposure to message frame intervention
Rating of agreement with statement "Individuals with opioid use disorder only have themselves to blame for their problem" on 5-point Likert scale with 5 indicating strong disagreement and 1 indicating strong agreement. Measured via survey questionnaire.
Rating of support for increasing government spending on opioid use disorder treatment
Time frame: Measured immediately post-exposure to message frame intervention
Rating of support for increasing government spending on treatment of opioid use disorder with 5 indicating strongly favoring and 1 indicating strongly opposing. Measured via survey questionnaire.
Feeling thermometer measure of warmth toward people with opioid use disorder
Time frame: Measured immediately post-exposure to message frame intervention
Rating of warmth felt toward people with opioid use disorder with 0 indicating extremely cold and 100 indicating extremely warm. Measured via survey questionnaire.
17 secondary outcomes
Stigmatizing Language - Addict
Time frame: Measured immediately post-exposure to message frame intervention
Stigmatizing Language - Substance abuse
Time frame: Measured immediately post-exposure to message frame intervention
Stigmatizing Language - dirty
Time frame: Measured immediately post-exposure to message frame intervention
Stigmatizing Language - clean
Time frame: Measured immediately post-exposure to message frame intervention
Stigmatizing Language - addicted baby
Time frame: Measured immediately post-exposure to message frame intervention
Stigmatizing Language - person with substance use disorder
Time frame: Measured immediately post-exposure to message frame intervention
Stigmatizing Language - substance use
Time frame: Measured immediately post-exposure to message frame intervention
Stigmatizing Language - negative test result
Time frame: Measured immediately post-exposure to message frame intervention
Stigmatizing Language - positive test result
Time frame: Measured immediately post-exposure to message frame intervention
Stigmatizing Language - baby born with neonatal opioid withdrawal syndrome
Time frame: Measured immediately post-exposure to message frame intervention
Willingness to sign pledge committing to using non-stigmatizing language
Time frame: Measured immediately post-exposure to message frame intervention
Perception of opioid use disorder treatment effectiveness
Time frame: Measured immediately post-exposure to message frame intervention
Rating of willingness to have person taking medication marry into their family
Time frame: Measured immediately post-exposure to message frame intervention
Rating of willingness to have person taking medication marry as a neighbor
Time frame: Measured immediately post-exposure to message frame intervention
Rating of strength/weakness of person taking medication
Time frame: Measured immediately post-exposure to message frame intervention
Rating of agreement that recovery is possible
Time frame: Measured immediately post-exposure to message frame intervention
Feeling thermometer measure of warmth toward people taking medication
Time frame: Measured immediately post-exposure to message frame intervention
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 Nov 2021.
- Derived from this study: PubMed 35119460Kennedy-Hendricks A, McGinty EE, Summers A, Krenn S, Fingerhood MI, Barry CL. Effect of Exposure to Visual Campaigns and Narrative Vignettes on Addiction Stigma Among Health Care Professionals: A Randomized Clinical Trial. JAMA Netw Open. 2022 Feb 1;5(2):e2146971. doi: 10.1001/jamanetworkopen.2021.46971.
- Individual participant dataSharing planned: No
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Sleep-Disordered Breathing, Chronic Opioid Use
Active, not recruitingPhase 2
Wellcome Leap Psilocybin for OUD
Opioid Use Disorder
Recruiting
Opioid and Pain Treatment in Indigenous Communities (OPTIC) Trial
Opioid Use Disorder, Opioid Misuse
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Alene Kennedy-Hendricks, PhD principal investigator
Johns Hopkins Bloomberg School of Public Health
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Words Matter - Visual Campaign, Words Matter - Visual Campaign & Narrative Vignette (Messenger: Person with Opioid Use Disorder) Experimental: Words Matter - Visual Campaign & Narrative Vignette (Messenger: Clinician) and Words Matter - Visual Campaign & Narrative Vignette (Messenger: Clinician) in people with Opioid Use Disorder and Substance Use Disorders, run by Johns Hopkins Bloomberg School of Public Health at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 19 Nov 2021. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Rating of willingness to have person with opioid use disorder marry into their family (time frame: Measured immediately post-exposure to message frame intervention). The study lists 6 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT05127707, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 Nov 2021.