HyperphagiaCemovNCT05200182
fNIRS-based Neurofeedback Intervention for Cognitive Control Improvement in Emotional Overeating
A study testing Neurofeedback with functional near infra-red spectroscopy, oral microbiota collection and Questionnaires in people with Hyperphagia, run by Rennes University Hospital at 1 site in France.
Trial summary
Emotional overeating is characterized by an excessive food intake in the context of intense emotional situations, such as acute stress one. Emotional overeating, as a behavioral trait, can increase the risk of to develop eating disorders or eating-related diseases, such as metabolic syndrome, obesity, type-2 diabetes. Read more about this study
- Who is it for?
- Ages 18 to 50 yearsHealthy volunteers can take part
- Conditions the study is for
- Hyperphagia
- What is being tested?
- Neurofeedback with functional near infra-red spectroscopy, oral microbiota collection and Questionnaires
- Type of treatment
- Pill or oral medicine, Medical device, Lifestyle or therapy programme
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 80 participants
- Where
- 1 siteFrance
- Study dates
- 7 Apr 2022to Jun 2028
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 50 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Normal Body Mass Index (18.5-25),
- Right-handlers
- Affiliated to a social security scheme
- Having given a free, informed and written consent
- Normal BMI (18.5-25),
- Right-handlers
Show all 9Show fewer
- Affiliated to a social security scheme
- Having given a free, informed and written consent
- Based on emotional overeating questionary : having emotional overeating episodes > 6 days in a month for at least one negative emotion
Who cannot join
- Related to the study - Insufficient command of French
- Related to Magnetic Resonance Imagine
- Implantable cardiac pacemaker or defibrillator;
- Neurosurgical clips;
- Cochlear implants;
- Neural or peripheral stimulator;
Show all 31Show fewer
- Foreign orbital or brain metallic foreign bodies;
- Endoprostheses implanted for less than 4 weeks and osteosynthesis materials placed for less than 6 weeks;
- Claustrophobia. Related to near infra Red spectroscopy
- Hairs that do not allow proper near infra Red spectroscopy measurement upon ligh blockage
- Study B
- Minimum age : 18 Years
- Maximum Age : 25 Years
- Sex : women
- Related to the study
- Insufficient command of French
- Excessive consumption of alcohol or other psychoactive substances (determined on the basis of the Alcohol Use Disorders Identification Test questionnaires - excluded if score > 12 and "Car, Relax, Alone, Forget, Friends, Trouble" questionnaire - excluded if score> 1 " yes ")
- Eating disorders ("sick, control, one stone, fat, food" questionnaire >2)
- Food addiction (Yale Food Addiction Score 2.0, score >2
- With psychoactive treatment
- Digestive or gastric disorders
- Related to magnetic resonance imaging
- Implantable cardiac pacemaker or defibrillator;
- Neurosurgical clips;
- Cochlear implants;
- Neural or peripheral stimulator;
- Foreign orbital or brain metallic foreign bodies;
- Endoprostheses implanted for less than 4 weeks and osteosynthesis materials placed for less than 6 weeks;
- Claustrophobia.
- Related to near infraRed spectroscopy
- Hairs that do not allow proper near infraRed spectroscopy measurement upon ligh blockage
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Nicolas COQUERY, PhD contact
France1 site, 1 recruiting
- Recruiting
Chu Rennes - Pontchaillou
Rennes, 35000
Romain Moirand, MD, romain.moirand@chu-rennes.fr
Nicolas COQUERY, nicolas.coquery@inrae.fr
About this study
Emotional overeating is characterized by an excessive food intake in the context of intense emotional situations, such as acute stress one. Emotional overeating, as a behavioral trait, can increase the risk of to develop eating disorders or eating-related diseases, such as metabolic syndrome, obesity, type-2 diabetes. Recently, imaging modalities, such as magnetic resonance imaging (MRI) and electro-encephalography (EEG), have been adapted in order to perform neurofeedback consisting on presenting the brain activity instantaneously to the participant, that give him the possibility to modify this activity by his own mean. Neurofeedback has already shown some efficacy, either with explicit or implicit instruction.
Compared with functional MRI (fMRI), functional near infra-red spectroscopy (fNIRS) is easy to handle, less expensive, and does not require a lying position. fNIRS is consequently more adapted for repeated acquisitions. Neurofeedback has already shown some promising results for neurological and psychiatric diseases. For mental states and emotion regulation, neurofeedback targeting the prefrontal cortex (PFC) has also shown promising outcomes. In this project, the investigators want to assess the effect of neurofeedback targeting the dorsolateral PFC (dlPFC) in a population of young adult women presenting emotional overeating. The investigators aim to improve the cognitive control and to reduce the episodes of emotional overeating in order to prevent the occurrence of subsequent pathologies.
Read more
The intervention effect will be characterized with: (i) fMRI in order to evaluate the effect on cognitive control (with resting state fMRI or rsMRI) and on the reward system; (II) questionaries directly and one month after intervention in order to assess the behavioral effect.
Besides an expected effect on emotional overeating, the investigators will evaluate whether an improvement of cognitive control can also promote positive effect on other behavioral traits that could lead to some pathologies such as food addiction.
As a prerequisite to this study on emotional overeating (study B), the investigators will firstly validate on healthy subjects (study A) a reward anticipation fMRI task, which will be further used in study A in order to characterized the effect of neurofeedback on the reward system.
- Conditions
- Hyperphagia
- Being tested
- Neurofeedback with functional near infra-red spectroscopy, Sham Neurofeedback, oral microbiota collection, Questionnaires, resting-state fMRI
- Keywords
- emotional overeating, functional near infraRed spectroscopy, neurofeedback, cognitive control
- Medical subject headings
- Hyperphagia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Neurofeedback with functional near infra-red spectroscopyDevice
the neurofeedback protocol will last 15 minutes per session, and during each session, the volunteer will have to increase the brain activity of his/her dorsolateral prefrontal cortex using a visual gauge representing the "activity level" of his/her own dorsolateral prefrontal cortex. No specific instructions will be given to the volunteer so that he/she can develop his/her own internal strategy to increase this "activity level".
Sham NeurofeedbackDevice
the participants will receive the same instruction but will be shown a random signal
oral microbiota collectionOther
an examination and oral swab for oral microbiota analysis will be performed by a dentist
QuestionnairesOther
questionnaires for pre-intervention behavioral characterization
resting-state fMRIDevice
characterize the brain function of volunteers by resting-state fMRI
Electro gastrogramDevice
Volunteers will also be equipped with an MRI-compatible electro-gastrogram device to correlate gastric signals with brain activity during rsMRI acquisition.
Emotional Stroop taskBehavioural
an emotional Stroop task adapted to food and body image representation
Delay discount taskBehavioural
Delay discount task
| Study group | Role | What they receive |
|---|---|---|
| Study A | Other | Validation of the reward system-related fMRI task, as determined by an increased activation on the brain reward structure (striatum) under the task. Receives: Device: Neurofeedback with functional near infra-red spectroscopy; Device: resting-state fMRI; Device: Electro gastrogram |
| Study B - Neurofeedback | Experimental | The neurofeedback protocol will be the same during the 8 sessions constituting the protocol and taking place over a period of 4 weeks (2 neurofeedback sessions per week, the first and the last one in an MRI context). It will last 15 minutes per session, and during each session, the volunteer will have to increase the brain activity of his/her dlPFC using a visual gauge representing the "activity level" of his/her own dlPFC. No specific instructions will be given to the volunteer so that he/she can develop his/her own internal strategy to increase this "activity level". Receives: Device: Neurofeedback with functional near infra-red spectroscopy; Other: oral microbiota collection; Other: Questionnaires; Device: resting-state fMRI; Device: Electro gastrogram; Behavioral: Emotional Stroop task; Behavioral: Delay discount task |
| Study B - Control | Sham comparator | In the control group with neurofeedback sham, the participants will receive the same instruction but will be shown a random signal, the goal being that the control strategy the participant tries to implement is not correlated with the visual feedback provided by the gauge. Receives: Device: Sham Neurofeedback; Other: oral microbiota collection; Other: Questionnaires; Device: resting-state fMRI; Device: Electro gastrogram; Behavioral: Emotional Stroop task; Behavioral: Delay discount task |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in cortico-striatal connectivity
Significant change in cortico-striatal connectivity as determined with resting state functional magnetic resonance imaging correlation coefficient between the first magnetic resonance imaging and the last magnetic resonance imaging visit
Measured: 4 weeks
Secondary outcomes (18)
Validate during a pilot study in a healthy population without emotional hyperphagia a functional MRI task of reward anticipation (Monetary and Food Incentive Delay task) to characterize the effect of NeuroFeedback.
healthy volunteers
Statistical increase of brain responses (BOLD signal variation) in motivation and reward brain regions determined with fMRI task to reward anticipation (Monetary and Food Incentive Delay task)
Measured: from enrollment to week 6
Validate a NeuroFeedback. approach targeting the nucleus accumbens by fMRI during sweet taste stimulation
Statistical increase of fMRI BOLD responses in nucleus accumbens to sweet taste oral stimulation
Measured: from enrollment to week 6
Statistical decreased in the score on the Emotional Overeating Questionnaire, evaluating emotional overeating, after vs before neurofeedback
healthy volunteers with emotional overeating
number of "emotions" driving equal or more than 6 days of overeating in a month, from 0 to 5
Measured: from enrollment to week 6
Evaluate by brain imaging (Monetary and Food Incentive Delay task in fMRI and basal cerebral perfusion) and behavioral questionnaires the effect of neurofeedback
healthy volunteers with emotional overeating
Neurofeedback will statistically decrease brain response (BOLD signal variation) in motivation and reward brain regions determined with fMRI task of reward anticipation for food (Monetary and Food Incentive Delay task)
Neurofeedback will increase basal cerebral perfusion in prefrontal brain regions.
Neurofeedback can modify statistically the outcome of behavioral questionaries (increase of controlling feeling during neurofeedback, from 1 : no control feeling, to 10: high control feeling)
Measured: from enrollment to week 10
Evaluate the variation of the indicators of viscera-brain communication
healthy volunteers with emotional overeating : oral microbiota and correlation of gastric rhythm by electrogastrogram and cerebral rhythm by resting state MRI
Neurofeedback will statistically increase the correlation between gastric oscillations measured with electrogastrogram and BOLD signal oscillations in brain stem regions involved in autonomic control of gastric rhythm, measured with resting state fMRI
Neurofeedback will statistically modify oral microbiota composition, considered as a proxy of eating habits, and measured as the percentage of each microbiota phylum (detected with DNA sequencing)
Measured: from enrollment to week 6
Variation in responses to an emotional Stroop task adapted to food and body image representation
Variation in responses to an emotional Stroop task adapted to food and body image representation
Measured: from enrollment to week 6
Modification of behavioral scores : Global Physical Activity Questionnaire
16 items, each of them corresponds, depending of the duration of physical activity, to a specific metabolic equivalent, with higher metabolic equivalent corresponding to higher physical activity)
Measured: from enrollment to week 10
Modification of behavioral scores : Internet Addiction Test
20 items, scale from 0 to 5, higher value corresponds to higher internet addiction
Measured: from enrollment to week 10
Modification of behavioral scores : Alcohol Use Disorders Identification Test
10 items, score from 0 to 4 for each, higher value corresponds to higher alcohol use disorder
Measured: from enrollment to week 10
Modification of behavioral scores : frequency of tobacco consumption
Measured: from enrollment to week 10
Modification of behavioral scores : Holmes and Rahe questionnaire
43 items to select or not, higher selected items number corresponds to higher life events stress value
Measured: from enrollment to week 10
Modification of behavioral scores : Barratt scale
34 items to select or not, higher selected items number corresponds to higher impulsivity
Measured: from enrollment to week 10
Link behavioral traits to neurofeedback success : CRAFFT (car, relax, alone, forget, friends, trouble)questionnaire
6 items, responses "yes" or "no", higher "yes" number corresponds to higher psychotropic substance consumption
Measured: from enrollment to week 6
Link behavioral traits to neurofeedback success : Boredom Proneness Scale
28 items, "true" or "false" answers, higher score corresponds to higher boredom proneness
Measured: from enrollment to week 6
Link behavioral traits to neurofeedback success : World Health Organization-Five Well-Being Index (WHO-5)
5 items, scores from 0 to 5, higher score corresponds to higher well-being
Measured: from enrollment to week 6
Link behavioral traits to neurofeedback success : Sick, Control, One stone, Fat Food (SCOFF)
4 items, "yes" or "no", higher number of "yes" corresponds to higher risk for eating disorder
Measured: from enrollment to week 6
Link behavioral traits to neurofeedback success : Three Factor Eating Questionnaire-R18
18 items, score from 1 to 4, higher score, depending of the different questions, correspond to higher dimension of eating behavior: cognitive restriction, disinhibition or control
Measured: from enrollment to week 6
Link behavioral traits to neurofeedback success : Delay discount task
multiple choice for different reward amount, for different delay before receiving this amount, higher amount for a short time to receive it corresponds to high impulsivity toward reward
Measured: from enrollment to week 6
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted20 Jan 2022
- Study start7 Apr 2022
- Primary completionJun 2028 (estimated)
- Study completionJun 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for HyperphagiaStudies of the same condition, open and under way.
- More trials run by Rennes University HospitalThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 80 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Rennes University Hospital
- Sponsor type
- University, hospital or other
- Collaborators
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
- Responsible party
- Sponsor
- Investigators
- Romain Moirand, MD, Principal investigator, Rennes University Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05200182
- Sponsor's protocol ID
- 35RC20_9849_Cemov
- Other IDs
- 2021-A02314-37
- Acronym
- Cemov
- Status last verified
- Sep 2026
- First submitted
- 6 Jan 2022
- Last updated
- 28 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 28 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- fNIRS-based Neurofeedback Intervention for Cognitive Control Improvement in Emotional Overeating
- ClinicalTrials.gov ID
- NCT05200182
- Acronym / sponsor ID
- Cemov / 35RC20_9849_Cemov
- Conditions
- Hyperphagia
- Keywords
- emotional overeating, functional near infraRed spectroscopy, neurofeedback, cognitive control
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 80 participants (estimated)
- Lead sponsor
- Rennes University HospitalUniversity, hospital or other
- Collaborators
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
- Study start
- 7 Apr 2022 (actual)
- Primary completion
- Jun 2028 (estimated)
- Study completion
- Jun 2028 (estimated)
- First posted
- 20 Jan 2022 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Emotional overeating is characterized by an excessive food intake in the context of intense emotional situations, such as acute stress one. Emotional overeating, as a behavioral trait, can increase the risk of to develop eating disorders or eating-related diseases, such as metabolic syndrome, obesity, type-2 diabetes. Recently, imaging modalities, such as magnetic resonance imaging (MRI) and electro-encephalography (EEG), have been adapted in order to perform neurofeedback consisting on presenting the brain activity instantaneously to the participant, that give him the possibility to modify this activity by his own mean. Neurofeedback has already shown some efficacy, either with explicit or implicit instruction.
Compared with functional MRI (fMRI), functional near infra-red spectroscopy (fNIRS) is easy to handle, less expensive, and does not require a lying position. fNIRS is consequently more adapted for repeated acquisitions. Neurofeedback has already shown some promising results for neurological and psychiatric diseases. For mental states and emotion regulation, neurofeedback targeting the prefrontal cortex (PFC) has also shown promising outcomes. In this project, the investigators want to assess the effect of neurofeedback targeting the dorsolateral PFC (dlPFC) in a population of young adult women presenting emotional overeating. The investigators aim to improve the cognitive control and to reduce the episodes of emotional overeating in order to prevent the occurrence of subsequent pathologies.
The intervention effect will be characterized with: (i) fMRI in order to evaluate the effect on cognitive control (with resting state fMRI or rsMRI) and on the reward system; (II) questionaries directly and one month after intervention in order to assess the behavioral effect.
Besides an expected effect on emotional overeating, the investigators will evaluate whether an improvement of cognitive control can also promote positive effect on other behavioral traits that could lead to some pathologies such as food addiction.
As a prerequisite to this study on emotional overeating (study B), the investigators will firstly validate on healthy subjects (study A) a reward anticipation fMRI task, which will be further used in study A in order to characterized the effect of neurofeedback on the reward system.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Study A | Other | Device: Neurofeedback with functional near infra-red spectroscopy, Device: resting-state fMRI, Device: Electro gastrogramValidation of the reward system-related fMRI task, as determined by an increased activation on the brain reward structure (striatum) under the task. |
| Study B - Neurofeedback | Experimental | Device: Neurofeedback with functional near infra-red spectroscopy, Other: oral microbiota collection, Other: Questionnaires, Device: resting-state fMRI, Device: Electro gastrogram, Behavioral: Emotional Stroop task, Behavioral: Delay discount taskThe neurofeedback protocol will be the same during the 8 sessions constituting the protocol and taking place over a period of 4 weeks (2 neurofeedback sessions per week, the first and the last one in an MRI context). It will last 15 minutes per session, and during each session, the volunteer will have to increase the brain activity of his/her dlPFC using a visual gauge representing the "activity level" of his/her own dlPFC. No specific instructions will be given to the volunteer so that he/she can develop his/her own internal strategy to increase this "activity level". |
| Study B - Control | Sham comparator | Device: Sham Neurofeedback, Other: oral microbiota collection, Other: Questionnaires, Device: resting-state fMRI, Device: Electro gastrogram, Behavioral: Emotional Stroop task, Behavioral: Delay discount taskIn the control group with neurofeedback sham, the participants will receive the same instruction but will be shown a random signal, the goal being that the control strategy the participant tries to implement is not correlated with the visual feedback provided by the gauge. |
Who may qualify
- Ages
- 18 to 50 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (9 listed)
- Normal Body Mass Index (18.5-25),
- Right-handlers
- Affiliated to a social security scheme
- Having given a free, informed and written consent
- Normal BMI (18.5-25),
Key exclusion criteria (31 listed)
- Related to the study - Insufficient command of French
- Related to Magnetic Resonance Imagine
- Implantable cardiac pacemaker or defibrillator;
- Neurosurgical clips;
- Cochlear implants;
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Neurofeedback with functional near infra-red spectroscopythe neurofeedback protocol will last 15 minutes per session, and during each session, the volunteer will have to increase the brain activity of his/her dorsolateral prefrontal cortex using a visual gauge representing the "activity level" of his/her own dorsolateral prefrontal cortex. No specific instructions will be given to the volunteer so that he/she can develop his/her own internal strategy to increase this "activity level". | Device | Study A, Study B - Neurofeedback |
| Sham Neurofeedbackthe participants will receive the same instruction but will be shown a random signal | Device | Study B - Control |
| oral microbiota collectionan examination and oral swab for oral microbiota analysis will be performed by a dentist | Other | Study B - Control, Study B - Neurofeedback |
| Questionnairesquestionnaires for pre-intervention behavioral characterization | Other | Study B - Control, Study B - Neurofeedback |
| resting-state fMRIcharacterize the brain function of volunteers by resting-state fMRI | Device | Study A, Study B - Control, Study B - Neurofeedback |
| Electro gastrogramVolunteers will also be equipped with an MRI-compatible electro-gastrogram device to correlate gastric signals with brain activity during rsMRI acquisition. | Device | Study A, Study B - Control, Study B - Neurofeedback |
| Emotional Stroop taskan emotional Stroop task adapted to food and body image representation | Behavioural | Study B - Control, Study B - Neurofeedback |
| Delay discount taskDelay discount task | Behavioural | Study B - Control, Study B - Neurofeedback |
Primary outcome
Change in cortico-striatal connectivity
Time frame: 4 weeks
Significant change in cortico-striatal connectivity as determined with resting state functional magnetic resonance imaging correlation coefficient between the first magnetic resonance imaging and the last magnetic resonance imaging visit
18 secondary outcomes
Validate during a pilot study in a healthy population without emotional hyperphagia a functional MRI task of reward anticipation (Monetary and Food Incentive Delay task) to characterize the effect of NeuroFeedback.
Time frame: from enrollment to week 6
Validate a NeuroFeedback. approach targeting the nucleus accumbens by fMRI during sweet taste stimulation
Time frame: from enrollment to week 6
Statistical decreased in the score on the Emotional Overeating Questionnaire, evaluating emotional overeating, after vs before neurofeedback
Time frame: from enrollment to week 6
Evaluate by brain imaging (Monetary and Food Incentive Delay task in fMRI and basal cerebral perfusion) and behavioral questionnaires the effect of neurofeedback
Time frame: from enrollment to week 10
Evaluate the variation of the indicators of viscera-brain communication
Time frame: from enrollment to week 6
Variation in responses to an emotional Stroop task adapted to food and body image representation
Time frame: from enrollment to week 6
Modification of behavioral scores : Global Physical Activity Questionnaire
Time frame: from enrollment to week 10
Modification of behavioral scores : Internet Addiction Test
Time frame: from enrollment to week 10
Modification of behavioral scores : Alcohol Use Disorders Identification Test
Time frame: from enrollment to week 10
Modification of behavioral scores : frequency of tobacco consumption
Time frame: from enrollment to week 10
Modification of behavioral scores : Holmes and Rahe questionnaire
Time frame: from enrollment to week 10
Modification of behavioral scores : Barratt scale
Time frame: from enrollment to week 10
Link behavioral traits to neurofeedback success : CRAFFT (car, relax, alone, forget, friends, trouble)questionnaire
Time frame: from enrollment to week 6
Link behavioral traits to neurofeedback success : Boredom Proneness Scale
Time frame: from enrollment to week 6
Link behavioral traits to neurofeedback success : World Health Organization-Five Well-Being Index (WHO-5)
Time frame: from enrollment to week 6
Link behavioral traits to neurofeedback success : Sick, Control, One stone, Fat Food (SCOFF)
Time frame: from enrollment to week 6
Link behavioral traits to neurofeedback success : Three Factor Eating Questionnaire-R18
Time frame: from enrollment to week 6
Link behavioral traits to neurofeedback success : Delay discount task
Time frame: from enrollment to week 6
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 28 Sep 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Nicolas COQUERY, PhD contact
Romain Moirand, MD principal investigator
Rennes University Hospital
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Neurofeedback with functional near infra-red spectroscopy, oral microbiota collection and Questionnaires in people with Hyperphagia, run by Rennes University Hospital at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 9 inclusion and 31 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 28 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Loïc JACOB (0299282555, loic.jacob@chu-rennes.fr), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in cortico-striatal connectivity (time frame: 4 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 28 Sep 2026.