AzTrials
AzTrials

Atherosclerotic Cardiovascular DiseasePhase 3PREVAILNCT05202509

Cardiovascular Outcome Study to Evaluate the Effect of Obicetrapib in Patients With Cardiovascular Disease

A Phase 3 study testing Obicetrapib in people with Atherosclerotic Cardiovascular Disease, run by NewAmsterdam Pharma at 591 sites in 23 countries.

Active, not recruiting

Under way, not looking for participants. Everyone needed has enrolled. The study is still running.

Official record
Search all trials

Trial summary

This study will be a placebo-controlled, double-blind, randomized, phase 3 study in participants with Atherosclerotic Cardiovascular Disease (ASCVD) who are not adequately controlled despite maximally tolerated lipid-lowering therapy. Read more about this study

Who is it for?
Ages 18 years and older
Conditions the study is for
Atherosclerotic Cardiovascular Disease
What is being tested?
Obicetrapib
Type of treatment
Pill or oral medicine
Could I receive a placebo?
Yes, some participants may receive a placebo
How many people
9,541 participants
Where
591 sitesin 23 countries
Study dates
7 Feb 2022to Nov 2026
Phase
Phase 3
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 years and older
  • All sexes
  • No healthy volunteers
  • Adult, Older adult

Who may be able to join

  • Males \& females ≥ 18 years age.
  • Established ASCVD including:
  • Coronary artery disease
  • Cerebrovascular disease
  • Peripheral Artery disease
  • On maximally tolerated lipid-modifying therapy
Show all 9Show fewer
  • Fasting LDL-C ≥ 55 mg/dL
  • Fasting triglycerides < 400 mg/dL
  • Estimated glomerular filtration rate ≥ 30 mL/min

Who cannot join

  • New York Heart Association class III or IV heart failure or left ventricular ejection fraction < 30%
  • Have been hospitalized for Heart Failure within 5 years prior to screening
  • Had non-fatal MI, non-fatal stroke, non-elective coronary revascularization and/or hospitalization for unstable angina or chest pain within past 3 months prior to screening
  • Uncontrolled hypertension
  • Diagnosis of homozygous familial hypercholesterolemia (HoFH)
  • Active liver disease
Show all 15Show fewer
  • HbA1c ≥10%
  • Thyroid Stimulating Hormone (TSH) > 1.5 times upper limit normal
  • Creatine kinase > 3 times upper limit normal
  • History of malignancy with surgery in past 3 years
  • History of alcohol or drug abuse within past 5 years
  • Received treatment with investigational product or device within past 30 days excluding Coronavirus treatment or vaccine
  • Known allergy to study drug
  • Participated in previous obicetrapib trial
  • Taking gemfibrozil within 30 days screening

Trial locations and contacts

591 sites in 23 countries.

591 sites in 23 countries

United States199 sites
  • Biofortis, Inc

    Addison, Illinois, 60101

  • New Mexico Clinical Research & Osteoporosis Center Inc.

    Albuquerque, New Mexico, 87106

  • Advanced Cardiovascular LLC

    Alexander City, Alabama, 35010

  • Cambridge Medical Trials

    Alexandria, Louisiana, 71301

  • PharmaTex Research, LLC

    Amarillo, Texas, 79109

  • Advanced Research Center

    Anaheim, California, 92805

  • Community Health Network-Anderson

    Anderson, Indiana, 46011

  • Northwest Heart Clinical research

    Arlington Heights, Illinois, 60005

  • Javara Inc - Wake Forest Health Network Family Physicians - Sunset Avenue

    Asheboro, North Carolina, 27203

  • Atlanta Diabetes Associates

    Atlanta, Georgia, 30318

  • Central Texas Clinical Research

    Austin, Texas, 78705

  • Accelemed Research Institute

    Austin, Texas, 78745

  • Northeast Cardiology Associates

    Bangor, Maine, 04401

  • Westside Medical Associates of Los Angeles

    Beverly Hills, California, 90211

  • Ascension - Cardiology Specialists of Birmingham

    Birmingham, Alabama, 35205

  • Central Alabama Research

    Birmingham, Alabama, 35209

  • Cardiovascular Associates of the Southeast, LLC

    Birmingham, Alabama, 35243

  • Excel Medical Clinical Trials

    Boca Raton, Florida, 33434

  • Advanced Heart Care, LLC

    Bridgewater, New Jersey, 08807

  • Burke Internal Medicine & Research

    Burke, Virginia, 22015

  • Hope Clinical Research LLC

    Canoga Park, California, 91303

  • East Coast Institute for Research - Canton

    Canton, Georgia, 30114

  • Cary Research Group, LLC

    Cary, North Carolina, 27518

  • The Presbyterian Hospital DBA Novant Health Heart and Vascular Institute

    Charlotte, North Carolina, 28204

  • Javara Inc - Tryon Medical Partners LLC

    Charlotte, North Carolina, 28210

  • Chattanooga Research & Medicine, PLLC

    Chattanooga, Tennessee, 37404

  • Javara Inc - Healthy Steps

    Chevy Chase, Maryland, 20815

  • IMA Clinical Research, PC

    Chicago, Illinois, 60602

  • Meridian Clinical Research - Cincinnati, OH

    Cincinnati, Ohio, 45219

  • Meridian Clinical Research - Springfield, OH

    Cincinnati, Ohio, 45246

  • Clearwater Cardiovascular and Interventional Consultants

    Clearwater, Florida, 33756

  • Innovative Research of West Florida

    Clearwater, Florida, 33756

  • Alpine Research Organization, Inc.

    Clinton, Utah, 84015

  • Private Practice - O. Alejandro Brusco, MD FACE PA

    Corpus Christi, Texas, 78414

  • West Broadway Clinic

    Council Bluffs, Iowa, 51501

  • Cardiovascular Associates Research, LLC - Covington, LA

    Covington, Louisiana, 70433

  • Clinical Research Collaborative, LLC

    Cumberland, Rhode Island, 02864

  • Atlanta Heart Specialists

    Cumming, Georgia, 30084

  • Javara Inc - Bridge Creek Family Medicine

    Cypress, Texas, 77433

  • Southwest Family Medicine Associates

    Dallas, Texas, 75325

  • Texas Health Research & Education Institute

    Dallas, Texas, 76107

  • PriMed Clinical Research

    Dayton, Ohio, 45419

  • Avail Clinical Research

    DeLand, Florida, 32720

  • The Iowa Clinic - Cardiovascular Services

    Des Moines, Iowa, 50266

  • Physicians' Research Options (PRO)

    Draper, Utah, 84020

  • Altoona Center for Clinical Research

    Duncansville, Pennsylvania, 16635

  • Alta Pharmaceutical Research Center

    Dunwoody, Georgia, 30338

  • Cardiology Care Clinic of Lake Oconee

    Eatonton, Georgia, 31024

  • South Texas Research Institute

    Edinburg, Texas, 78539

  • David Turbay, MD, PLLC

    El Paso, Texas, 79905

  • Midwest Cardiovascular Research and Education Foundation

    Elkhart, Indiana, 46514

  • Titan Medical Research - Oceanside

    Encinitas, California, 92024

  • Eastern Shore Research Institute, LLC

    Fairhope, Alabama, 36532

  • Lillestol Research LLC

    Fargo, North Dakota, 58104

  • Aa Mrc, Llc

    Flint, Michigan, 48504

  • Invesclinic

    Fort Lauderdale, Florida, 33308

  • Piedmont Research Partners, LLC

    Fort Mill, South Carolina, 29707

  • Javara Inc - Texas Health Care Family Physicians

    Fort Worth, Texas, 76132

  • Valley Institute of Research - Fort Worth

    Fort Worth, Texas, 76164

  • Mt. Olympus Medical Research

    Friendswood, Texas, 77546

  • Stern Cardiovascular Foundation, Inc

    Germantown, Tennessee, 38138

  • Healthy Heart Cardiology

    Grand Rapids, Michigan, 49564

  • Prevea Health

    Green Bay, Wisconsin, 54303

  • Moses H. Cone Memorial Hospital Operating Corporation d/b/a Cone Health

    Greensboro, North Carolina, 27401

  • Medication Management, LLC

    Greensboro, North Carolina, 28210

  • Clinical Investigation Specialists

    Gurnee, Illinois, 60031

  • Mass General Brigham Pentucket Medical Associates - Haverhill

    Haverhill, Massachusetts, 01830

  • Apex Medical Research

    Hazel Crest, Illinois, 60429

  • Qway Research

    Hialeah, Florida, 33010

  • New Generation of Medical Research

    Hialeah, Florida, 33016

  • Abington Medical Specialists, P.C. dba AMS Cardiolog

    Horsham, Pennsylvania, 19044

  • East Texas Cardiology, PA

    Houston, Texas, 77002

  • Angiocardiac Care of Texas

    Houston, Texas, 77025

  • Texas Heart Institute

    Houston, Texas, 77030

  • Southwest Clinical Trials

    Houston, Texas, 77074

  • BioStar Clinical Research

    Houston, Texas, 77094

  • Texas Center for Drug Development

    Houston, Texas, 77375

  • The Heart Center Research

    Huntsville, Alabama, 35801

  • Hutchinson Clinic

    Hutchinson, Kansas, 67502

  • Medstar Health Research Institute

    Hyattsville, Maryland, 20782

  • Community Health Network

    Indianapolis, Indiana, 46227

  • East Coast Institute for Research

    Jacksonville, Florida, 32086

  • East Coast Institute for Research - Jacksonville Monroe St

    Jacksonville, Florida, 32204

  • East Coast Institute for Research - Jacksonville University Blvd

    Jacksonville, Florida, 32216

  • East Coast Institute for Research - Perimeter Park Court

    Jacksonville, Florida, 32216

  • NSC Research

    Johns Creek, Georgia, 30024

  • NEA Baptist clinic

    Jonesboro, Arkansas, 72405

  • West Houston Area Clinical Trial Consultants, LLC

    Katy, Texas, 77493

  • Clinical Investigation Specialists

    Kenosha, Wisconsin, 53144

  • Holston Medical Group

    Kingsport, Tennessee, 37660

  • New Phase Research & Development

    Knoxville, Tennessee, 37909

  • East Coast Institute for Research- Lake City

    Lake City, Florida, 32055

  • Milton Haber, M.D

    Laredo, Texas, 78041

  • Sierra Clinical Research

    Las Vegas, Nevada, 89106

  • AB Clinical Trials

    Las Vegas, Nevada, 89119

  • Advanced Biomedical Research of America

    Las Vegas, Nevada, 89123

  • Clinical Trials of America, LLC - Lenoir, NC

    Lenoir, North Carolina, 28645

  • The Research Group of Lexington, LLC

    Lexington, Kentucky, 40503

  • Nexgen Research

    Lima, Ohio, 45805

  • Clinical Trials Research

    Lincoln, California, 95648

  • Meridian Clinical Research- Lincoln, NE

    Lincoln, Nebraska, 68510

  • Cardiology and Medicine Clinic

    Little Rock, Arkansas, 72204

  • Torrance Clinical Research Institute Inc.

    Lomita, California, 90717

  • American Institute of Research

    Los Angeles, California, 90211

  • Louisville Metabolic and Atherosclerosis Research Center (L-MARC)

    Louisville, Kentucky, 40213

  • Carient Heart & Vascular

    Manassas, Virginia, 20109

  • SV Research

    Marion, Ohio, 43302

  • Advanced Medical Research (AMR)

    Maumee, Ohio, 43537

  • ActivMed Practices and Research - Methuen

    Methuen, Massachusetts, 01844

  • Columbus Clinical Services

    Miami, Florida, 33125

  • Finlay Medical Research Corp

    Miami, Florida, 33126

  • A+ Research Inc

    Miami, Florida, 33144

  • Ezy Medical Research

    Miami, Florida, 33175

  • ProLive Medical Research

    Miami, Florida, 33175

  • Med Research of Florida, LLC

    Miami, Florida, 33186

  • Montana Medical Research, Inc.

    Missoula, Montana, 59808

  • Mobile Heart Specialists

    Mobile, Alabama, 36608

  • Diabetes and Endocrinology Consultants, P.C

    Morehead City, North Carolina, 28557

  • Burke Primary Care

    Morganton, North Carolina, 28655

  • McLaren Macomb Regional Medical Center

    Mount Clemens, Michigan, 48043

  • Inspira Medical Centers

    Mullica Hill, New Jersey, 08302

  • ASHA Clinical Research - Munster, LLC

    Munster, Indiana, 46321

  • Cardiovascular Research of Northwest Indiana, LLC

    Munster, Indiana, 46321

  • Syed Research Consultants

    Muscle Shoals, Alabama, 35661

  • New Generation of Medical Research - Naples

    Naples, Florida, 34104

  • BTC of New Bedford

    New Bedford, Massachusetts, 02740

  • Advanced Research Institute Inc

    New Port Richey, Florida, 34653

  • Mid-Hudson Medical Research, PLLC - New Windsor

    New Windsor, New York, 12553

  • IMA Clinical Research PC and Affiliates- New York, NY

    New York, New York, 10036

  • York Clinical Research LLC

    Norfolk, Virginia, 23510

  • Lynn Institute of Norman

    Norman, Oklahoma, 73072

  • DiGiovanna Institute for Medical Education and Research

    North Massapequa, New York, 11758-1802

  • North Hills Medical Research, Inc.

    North Richland Hills, Texas, 76180

  • Amicis Research Center-Northridge

    Northridge, California, 91324

  • Amicis Research

    Northridge, California, 91324

  • Valley Clinical Trials, Inc

    Northridge, California, 91325

  • Cardiology Associates of Fairfield County

    Norwalk, Connecticut, 06905

  • Advocate Health and Hospitals Corporation

    Oakbrook Terrace, Illinois, 60657

  • Ocala Research Institute

    Ocala, Florida, 34471

  • Lynn Health Science Institute - East

    Oklahoma City, Oklahoma, 73111

  • South Carolina Clinical Research LLC

    Orangeburg, South Carolina, 29118

  • Ormond Beach Clinical Research LLC

    Ormond Beach, Florida, 32174

  • Research Integrity

    Owensboro, Kentucky, 42303

  • Tapia Internal Medicine Clinic

    Paris, Texas, 75460

  • Linq Research, LLC

    Pearland, Texas, 60602

  • Elite Clinical Studies

    Phoenix, Arizona, 85018

  • Pinehurst Medical Clinic, Inc.

    Pinehurst, North Carolina, 28374

  • Preferred Primary Care Physicians Group - Pleasant Hills

    Pittsburgh, Pennsylvania, 15236

  • Styde Research

    Plano, Texas, 75093

  • Cardiovascular Research of Knoxville

    Powell, Tennessee, 37849

  • Monument Health Clinical Research, a department of Monument Health Rapid City Hospital, Inc

    Rapid City, South Dakota, 57701

  • Dominion Medical Associates

    Richmond, Virginia, 23219

  • Advanced Cardiology Associates

    Rochester Hills, Michigan, 49546

  • Optimal Research, LLC

    Rockville, Maryland, 32763

  • Endocrine Research Solutions, Inc

    Roswell, Georgia, 30076

  • Heart and Vascular Center at Methodist Hospital

    Saint Louis Park, Minnesota, 55416

  • Wasatch Clinical Research

    Salt Lake City, Utah, 84102

  • Sun Research Institute

    San Antonio, Texas, 78215

  • San Antonio Premier Internal Medicine

    San Antonio, Texas, 78220

  • Bandera Family HealthCare Research, LLC (BFHC)

    San Antonio, Texas, 78249

  • Headlands Research

    Sarasota, Florida, 34243

  • Saratoga Clinical Research

    Saratoga Springs, New York, 12866

  • Javara Inc - SouthCoast Health

    Savannah, Georgia, 31406

  • Syed Research Consultants

    Sheffield, Alabama, 35660

  • Sherman Clinical Research

    Sherman, Texas, 75092

  • Hillcrest Clinical Research

    Simpsonville, South Carolina, 29681

  • Louisiana Heart Center

    Slidell, Louisiana, 70458

  • Frontier Clinical Research

    Smithfield, Pennsylvania, 15478

  • Cardio Metabolic Institute

    Somerset, New Jersey, 08873

  • Revival Research Institute

    Southgate, Michigan, 48195

  • IMA Clinical Research - St. Louis, MO

    St Louis, Missouri, 63117

  • St. Louis Heart and Vascular Cardiology

    St Louis, Missouri, 63136

  • Piedmont Healthcare - Statesville

    Statesville, North Carolina, 28625

  • Stephenville Medical & Surgical Clinic

    Stephenville, Texas, 76401

  • Clinical Research Institute of Arizona, LLC

    Sun City West, Arizona, 85375

  • Herman Clinical Research

    Suwanee, Georgia, 30024

  • MultiCare Institute for Research and Innovation- Tacoma

    Tacoma, Washington, 98405

  • Universal Research Group LLC

    Tacoma, Washington, 98405

  • BayCare Health System

    Tampa, Florida, 33614

  • JSV Clinical Research Study, Inc

    Tampa, Florida, 33634

  • Chear Center LLC

    The Bronx, New York, 10455

  • Javara Inc - Highland Woods Health

    The Woodlands, Texas, 77382

  • Lundquist Institute for Biomedical Innovation at Harbor UCLA Medical Center

    Torrance, California, 90502

  • Oakland Medical Research Center

    Troy, Michigan, 48085

  • Arcturus Healthcare

    Troy, Michigan, 48098

  • Eclipse Clinical Research

    Tucson, Arizona, 85745

  • Meridian Clinical Research- Endwell, NY

    Vestal, New York, 13760

  • Cardiology Partners Clinical Research Institute

    Wellington, Florida, 33449

  • Clinical Trials of America

    West Monroe, Louisiana, 71291

  • Southgate Medical Group

    West Seneca, New York, 14224

  • Great Lakes Medical Research, LLC

    Westfield, New York, 14787

  • Kansas Nephrology Research Institute

    Wichita, Kansas, 67214

  • West Houston Area Clinical Trial Consultants

    Wichita, Kansas, 67226

  • Wilmington Health Associates

    Wilmington, North Carolina, 28412

  • Wake Forest University Health Sciences

    Winston-Salem, North Carolina, 27157

  • Clinical Research of Central Florida

    Winter Haven, Florida, 33880

  • Penn State Health Medical Group- Berks Cardiology

    Wyomissing, Pennsylvania, 19610

  • Michigan Heart

    Ypsilanti, Michigan, 48197

  • Southern Clinical Research, LLC

    Zachary, Louisiana, 70791

Other trials in United States

Poland48 sites
  • CENTRUM MEDYCZNE INTERCOR Sp. z o.o.

    Bydgoszcz, 85-605

  • Centrum Medyczne Pratia Bydgoszcz

    Bydgoszcz, 85-796

  • Centrum Medyczne Kermed - Renata Bijata-Bronisz I Ewa Kowalinska Spólka Jawna

    Bydgoszcz, 85231

  • DIAB Serwis Popenda Spólka Jawna

    Chorzów, 41-500

  • NZOZ Twoje Zdrowie EL Sp. z o.o.

    Elblag, 82-300

  • Indywidualna Specjalistyczna Praktyka Lekarska dr n. med. Adam Grzybowski

    Gdansk, 80-262

  • Uniwersyteckie Centrum Kliniczne, I Klinika Kardiologii

    Gdansk

  • Indywidualna Specjalistyczna Praktyka Lekarska w Dziedzinie Kardiologii, lek. med. Krzysztof Cymerman

    Gdynia, 81-157

  • Samodzielny Publiczny Specjalistyczny Szpital Zachodni im. Jana Pawla II

    Grodzisk Mazowiecki

  • Centrum Medyczne Pratia Katowice

    Katowice, 40-081

  • SALVIA Lekston i Madej s.j.

    Katowice, 40-675

  • Silmedic Sp. z o.o.

    Katowice

  • Ewa Mirek-Bryniarska Specjalistyczna Praktyka Lekarska

    Krakow, 30-082

  • Pratia MCM Krakow

    Krakow, 30-510

  • Krakowski Szpital Specjalistyczny im. Jana Pawla II - Oddzial Kliniczny Kardiologii Interwencyjnej z Pododdzialem Intenyswengo Nadzoru Kardiologicznego

    Krakow, 31-202

  • Centrum Medyczne ZDROWA

    Krakow, 31-216

  • Krakowskie Centrum Medyczne Sp. z o.o.

    Krakow, 31-501

  • ETG Lodz - Santa Sp. z. o.o.

    Lodz, 90-302

  • FutureMeds Lodz

    Lodz, 91-363

  • INSTYTUT CENTRUM ZDROWIA MATKI POLKI - Klinika Kardiologii i Wad Wrodzonych Doroslych

    Lodz, 93-338

  • Indywidualna Specjalistyczna Praktyka Lekarska Wlodzimierz Kus

    Lodz, 94-255

  • Clinical Best Solutions - Lublin

    Lublin, 20-078

  • KO - MED Centra Kliniczne Lublin II

    Lublin, 20-362

  • ETG Lublin - Pro Life Medica Sp. z o.o

    Lublin, 20-412

  • Szpital Sw. Anny w Miechowie

    Miechów, 32-086

  • Pomorskie Centra Kardiologiczne Sp. z o.o., SKA - Mragowo

    Mrągowo

  • ZOZ w Olawie, Oddzial Chorob Wewnetrznych

    Oława, 55-200

  • Futuremeds Olsztyn

    Olsztyn, 10-010

  • Ostrowieckie Centrum Medyczne spólka cywilna Anna Olech-Cudzik

    Ostrowiec Świętokrzyski

  • Centrum Medyczne OMEDICA Jaroslaw Opiela i Beata Opiela s. j.

    Poznan, 60-111

  • NZOZ Neuro-Kard - Ilkowski i Partnerzy Spólka Partnerska Lekarzy

    Poznan, 61-853

  • Aka-Med Centrum Spólka Z Ograniczona Odpowiedzialnoscia

    Ruda Śląska, 41-710

  • ETG Siedlce- Lukmed 2 Sp. z o.o.

    Siedlce, 08-110

  • ETG Skierniewice - ClinMedica Research Sp. z o.o.

    Skierniewice, 96-100

  • NZOZ Pro Cordis Sopockie Centrum Badan Kardiologicznych

    Sopot, 81-423

  • Nowe Zdrowie-Ck Kieltucki i Wspolnicy Spolka Jawna

    Staszów

  • Osrodek Badan Klinicznych LabMed Agnieszka Karczmarczyk, Filip Karczmarczyk Spólka Cywilna

    Szczecin, 71-526

  • Prywatny Gabinet Lekarski Jacek Gessek

    Torun, 87-100

  • FutureMeds Warszawa Centrum

    Warsaw, 00-215

  • ETG Warszawa- MCM Polimedica 2 Sp. z o.o.

    Warsaw, 02-793

  • FutureMeds Targowek

    Warsaw, 03-291

  • Clinical Best Solutions Sp. z.o.o Spolka Komandytowa

    Warsaw

  • Narodowy Instytut Kardiologii Stefana kardynala Wyszynskiego - Panstwowy Instytut Badawczy, Poradnia Prewencji i Leczenia Chorob Metabolicznych, Zaklad Epidemiologii, Prewencji Chorób Ukladu Krazeni

    Warsaw

  • FutureMeds Sp. z o.o

    Wroclaw, 50-088

  • 4 Wojskowy Szpital Kliniczny z Poliklinika Samodzielny Publiczny ZOZ we Wroclawiu

    Wroclaw, 50-981

  • Wroclawska Grupa Medyczna Pankiewicz Spolka Jawna

    Wroclaw, 53-149

  • ETG Zamosc - Pro Life Medica Sp. z o.o

    Zamość, 22 - 400

  • KO - MED Centra Kliniczne Sp. z o.o., Osrodek Badan Klinicznych w Zamosciu

    Zamość, 22-400

Other trials in Poland

Bulgaria35 sites
  • MHAT Aytos EOOD Department of Internal Diseases

    Aytos, 8500

  • Medical Center Doctor Staykov EOOD

    Burgas, 8000

  • UMHAT Deva Maria

    Burgas

  • Medical Center Viva Feniks

    Dobrich, 9300

  • MHAT Sveti Ivan Rilski

    Gorna Oryahovitsa, 5100

  • MHAT Haskovo AD

    Haskovo, 6300

  • MHAT City Clinic - Sveti Georgi EOOD

    Montana, 3400

  • Medical Center - Cordis OOD

    Pleven, 5800

  • MHAT Heart and Brain Pleven

    Pleven, 5800

  • Medical Center for Rehabilitation and Sports Medicine I - Plovdiv EOOD

    Plovdiv, 4002

  • UMHAT Sveti Georgi EA

    Plovdiv, 4002

  • Medical Center Rusemed EOOD

    Rousse, 7000

  • SHATC Medica Cor EAD

    Rousse, 7013

  • Multiprofile Hospital for Active Treatment (MHAT)- Silistra

    Silistra

  • MHAT Dr. Ivan Seliminski AD

    Sliven, 8800

  • Medical Center for Specialized Medical Help in Cardiovascular Diseases OOD

    Sofia, 1000

  • MHAT Sveta Sofia EOOD

    Sofia, 1000

  • Diagnostic and Consulting Center 22 - Sofia

    Sofia, 1113

  • DCC "Ascendent"

    Sofia, 1202

  • Diagnostic consultative center 24

    Sofia, 1231

  • National Multiprofile Transport Hospital Tsar Boris Treti - Cardiology Clinic

    Sofia, 1233

  • Medical Centre Medcross

    Sofia, 1309

  • Diagnostic Consulting Center Convex EOOD

    Sofia, 1680

  • MC Doctor Kalchev OOD

    Sofia, 1700

  • "Medical Center Medic" OOD

    Sofia

  • Multiprofile Hospital for Active Treatment National Cardiology Hospital

    Sofia

  • CardioArt Medical Center

    Stara Zagora, 6000

  • Medical Center Zara - Med

    Stara Zagora, 6003

  • UMHAT Prof. Dr. Stoyan Kirkovich

    Stara Zagora, 6003

  • Diagnostic Consultative Center Chaika

    Varna, 9000

  • Medical Center Plazmamed Clinic

    Varna, 9000

  • Specialized Hospital for Active Treatment of Cardiology

    Varna, 9020

  • Medical Center Medica Plus OOD

    Veliko Tarnovo, 5006

  • Medical Center Nevromedics

    Veliko Tarnovo

  • Medical Center Velingrad 2017 EOOD

    Velingrad, 4600

Other trials in Bulgaria

Germany32 sites
  • Kardiologische Praxis Dr. med. univ. Wolfgang Jungmair

    Bad Homburg

  • kfgn | Site Operations & Services GmbH - Berlin-Mitte

    Berlin, 10117

  • Franziskus Hospital Berlin

    Berlin, 10787

  • Diabetespraxis Dr. Braun

    Berlin, 13187

  • Kardiologisch-Angiologische Praxis - Herzzentrum Bremen

    Bremen

  • MVZ am Küchwald GmbH

    Chemnitz

  • Gemeinschaftspraxis Diabeteszentrum Dortmund

    Dortmund

  • St Johannes Hospital Dortmund

    Dortmund

  • Kfgn | Site Operations & Services GmbH - Dresden

    Dresden, 1069

  • Universitaetsklinikum Carl Gustav Carus Dresden

    Dresden

  • ZKS - Zentrum Klinische Studien Sudbrandenburg GmbH

    Elsterwerda, 4910

  • Katholisches Krankenhaus St. Johann Nepomuk

    Erfurt

  • Klinisches Forschungszentrum Dr. Hagemann

    Essen

  • Studienzentrum Bocholderstrasse

    Essen

  • Zentrum für Klinische Studien (diabetes-falkensee.de)

    Falkensee

  • ClinPhenomics CVC GmbH

    Frankfurt, 60596

  • Diabeteszentrum Hamburg West (DZHW) / Gemeinschaftspraxis Dr. Wendisch, Dr. Dahl und Prof. Dr. Aberle

    Hamburg

  • St. Josefskrankenhaus Heidelberg GmbH

    Heidelberg, 69115

  • Universitaetsklinikum Schleswig-Holstein Campus Kiel

    Kiel, 24105

  • Velocity Clinical Research Leipzig GmBH

    Leipzig, 4103

  • Diabetologikum DDG Ludwigshafe

    Ludwigshafen

  • Kliniken Maria Hilf GmbH Krankenhaus St. Franziskus

    Mönchengladbach, 41063

  • CDG Studienambulanz Dr. Hartard

    München

  • Klinikum München Klinik Neuperlach

    München

  • Praxis Drs. Haggenmiller/Jeserich

    Nuremberg

  • RED-Institut GmbH

    Oldenburg in Holstein, 23758

  • Praxis Reinfeld Mitte

    Reinfeld

  • Herz Kreislauf Zentrum - Klinikum Hersfeld Rotenburg GmbH

    Rotenburg (Wümme), 36199

  • Studienzentrum Brinkum

    Stuhr

  • Gemeinschaftspraxis Dr. med. Josef und Dr. med. Wilma Grosskopf

    Wallerfing

  • Forschungszentrum Ruhr

    Witten, 58455

  • INFO-MED Leipzig GmbH

    Zwenkau, 4442

Other trials in Germany

United Kingdom27 sites
  • Ulster Hospital

    Belfast

  • FutureMeds - Soho Road Health Centre

    Birmingham, B21 9RY

  • Birmingham Heartlands Hospital

    Birmingham, B9 5SS

  • Waterloo Medical Centre

    Blackpool, FY4 3AD

  • University Hospital of Wales

    Cardiff, CF14 4XW

  • FutureMeds - Ely Bridge Surgery

    Cardiff, CF5 4AD

  • Darlington Memorial Hospital

    Durham, DL3 6HX

  • Panthera - London North

    Enfield, EN3 4GS

  • Fowey River Practice

    Fowey, PL23 1DT

  • Panthera - Glasgow

    Glasgow, G51 4LB

  • Futuremeds - CPS Research

    Glasgow

  • Hounslow Medical Centre

    Hounslow, TW3 3ET

  • St. Bartholomew's Hospital

    London, EC1M 6BQ

  • The Good Practice

    London, SW10 0LR

  • Chelsea and Westminster Hospital

    London, TW7 6AF

  • Luton and Dunstable University Hospital

    Luton, LU4 0DZ

  • FutureMeds - Bridle Road Clinic

    Metropolitan Borough of Wirral, CH62 6EE

  • Atlantic Medical Group

    Penzance, Cornwall, TR18 3DX

  • Mounts Bay Medical

    Penzance, Cornwall, TR19 7HU

  • Beacon Medical Group

    Plymouth, PL7 2QP

  • Craigavon Area Hospital

    Portadown

  • Panthera - Preston

    Preston, PR2 9QB

  • Panthera - Manchester

    Rochdale, OL11 4AU

  • Queens Hospital

    Romford

  • Panthera - Sheffield

    Sheffield, S2 5FX

  • Sandwell General Hospital

    West Bromwich

  • Worcestershire Royal Hospital

    Worcester, WR5 1DD

Other trials in United Kingdom

Hungary25 sites
  • Lausmed Kft

    Baja

  • Tagore Medical Center

    Balatonfüred, 8230

  • Dr Lakatos Ferenc Belgyogyaszati-Kardiologiai Maganrendelo

    Békéscsaba, 5600

  • Qualiclinic Kft

    Budapest, 1036

  • Semmelweis Egyetem - Szent Rokus Klinikai Tomb

    Budapest, 1085

  • Del-pesti Centrumkorhaz

    Budapest, 1097

  • MED-TIMA Kft

    Budapest, 1132

  • Obudai Egeszsegugyi Centrum - Budapest

    Budapest, H-1036

  • Semmelweis Egyetem - Varosmajori Sziv es Ergyogyaszati Klinika

    Budapest, H-1122

  • Clinexpert Kft.

    Budapest

  • High Tech Medical Kft

    Budapest

  • Belinus Bt

    Debrecen, 4025

  • CRU Hungary Kft.

    Encs, H-3860

  • Pharma4 Trial Kft

    Gyöngyös

  • BKS Research Kft.

    Hatvan, 3000

  • Porcika Klinik

    Hódmezővásárhely

  • Somogy Varmegyei Kaposi Mor Oktato Korhaz

    Kaposvár

  • Pest M. Flór F. Kórház V. Belgy. Oszt

    Kistarcsa, H- 2143

  • Kistarcsai Flor Ferenc Korhaz

    Kistarcsa

  • IPR Hungary Kft

    Miskolc

  • dr Vasas Szilard Haziorvosi Rendelo

    Nyíregyháza, 4405

  • Medifarma-98 Kft

    Nyíregyháza, H-4400

  • dr Nagy Laszlo Kardiologiai Maganrendeles es Klinikai Vizsgalohely

    Orosháza, 5900

  • Coromed SMO Kft

    Pécs

  • Obudai Egeszsegugyi Centrum - Zalaegerszeg

    Zalaegerszeg, 8900

Other trials in Hungary

Slovakia24 sites
  • Stredoslovensky ustav srdcovych a cievnych chorob, a.s.

    Banská Bystrica, 974 01

  • Alian, s.r.o., Kardiologicka ambulancia

    Bardejov, 085 01

  • DIADA s.r.o.

    Bardejov, 085 01

  • Thyreomedical s.r.o.

    Bardejov

  • Medispektrum s.r.o., Diabetologicka a metabolicka ambulancia

    Bratislava

  • Univerzitna nemocnica Bratislava

    Bratislava

  • Kardiologicka ambulancia NsP, n.o.

    Brezno, 977 01

  • JM-INTERNA, s.r.o., Ambulancia vnutorneho lekarstva

    Dolný Kubín

  • Cardio D&R, S.R.O. Kosice

    Košice, 040 22

  • Human-Care s.r.o

    Košice, 4001

  • Medical group Kosice, s.r.o. - Kardiologicka a Interna ambulancia

    Košice, 4001

  • KardioLEV s. r. o.

    Levoča, 054 01

  • Kardiomed s.r.o.

    Lučenec, 984 01

  • KARDIO 1 s.r.o.

    Lučenec, 98401

  • Interna a diabetologicka ambulancia - IN - DIA s.r.o., MUDr. Livia Tomasova

    Lučenec

  • Univerzitna nemocnica Martin

    Martin

  • Medi M and M sro

    Moldava nad Bodvou

  • Kardiocentrum Nitra s.r.o.

    Nitra, 949 01

  • Medical KG, s.r.o. - Ambulancia vnutorneho lekarstva

    Piešťany, 92101

  • Medispol, s.r.o.

    Prešov

  • Tatratrial s.r.o

    Rožňava

  • Interna SK, s.r.o., Kardiologicka a interna ambulancia

    Svidník, 8901

  • JAL s.r.o.

    Trnava, 917 01

  • Medivasa, s.r.o., Angiologicka a kardiologicka ambulancia

    Žilina, 1001

Other trials in Slovakia

Japan21 sites
  • Chiba University Hospital

    Chiba, 260-8677

  • New Tokyo Heart Clinic

    Chiba, 271-0077

  • Kokura Memorial Hospital

    Fukuoka, 802-8555

  • Japan Community Health Care Organization Kyushu Hospital

    Fukuoka, 806-8501

  • National Hospital Organization Takasaki General Medical Center

    Gunma, 370-0829

  • Hiroshima Prefectural Hospital

    Hiroshima, 734-8530

  • Hiroshima University Hospital

    Hiroshima, 734-8551

  • Hyogo Prefectural Harima-Himeji General Medical Center

    Hyōgo, 670-8560

  • Ishikawa Prefectural Central Hospital

    Ishikawa, 920-8530

  • Komatsu Municipal Hospital

    Ishikawa, 923-8560

  • Public Central Hospital of Matto lshikawa

    Ishikawa, 924-8588

  • Showa University Northern Yokohama Hospital

    Kanagawa, 224-8503

  • Yokohama Minami Kyousai Hospital

    Kanagawa, 236-0037

  • Niigata University Medical & Dental Hospital

    Niigata, 951-8510

  • The Sakakibara Heart Institute of Okayama

    Okayama, 700-0804

  • Sakurabashi Watanabe Hospital

    Osaka, 530-0001

  • Saiseikai Senri Hospital

    Osaka, 565-0862

  • National Cerebral and Cardiovascular Center Research Institute

    Osaka, 565-8565

  • Osaka Medical and Pharmaceutical University Hospital

    Osaka, 569-8686

  • Tokyo Saiseikai Central Hospital

    Tokyo, 108-0073

  • Nihon University Itabashi Hospital

    Tokyo, 173-8610

Other trials in Japan

Netherlands21 sites
  • Academic Medical Center - Department of Vascular Medicine

    Amsterdam, 1105AZ

  • Ziekenhuis Rijnstate

    Arnhem, 6815 AD

  • Rode Kruis Ziekenhuis

    Beverwijk, 1942 LE

  • Reinier de Graaf Gasthuis

    Delft, 2625 AD

  • Het Van Weel-Bethesda Ziekenhuis

    Dirksland, 3247 BW

  • Albert Schweitzer Ziekenhuis - Location Dordrecht

    Dordrecht, 3331 LZ

  • Ziekenhuis Gelderse Vallei

    Ede, 6716 RP

  • Maxima Medisch Centrum

    Eindhoven, 5504 DB

  • Groene Hart Ziekenhuis

    Gouda, 2803 HH

  • St. Jansdal Ziekenhuis

    Harderwijk, 3844 DG

  • Elkerliek Ziekenhuis - Locatie Helmond

    Helmond, 5707 HA

  • Treant Zorggroep

    Hoogeveen, 7827

  • Leids Universitair Medisch Centrum

    Leiden, 2333 ZA

  • Stichting Radboud Universitair Medisch Centrum

    Nijmegen, 6525 GA

  • Canisius-Wilhelmina Ziekenhuis (CWZ)

    Nijmegen, 6532 SZ

  • Franciscus Gasthuis & Vlietland - Locatie Gasthuis

    Rotterdam, PM 3045

  • HMC Westeinde

    The Hague, 2512 VA

  • Diakonessenhuis - Locatie Utrecht

    Utrecht, 3582 KE

  • VieCuri Medisch Centrum

    Venlo, 5912 BL

  • Zaans Medisch Centrum

    Zaandam, 1502 DV

  • Albert Schweitzer Ziekenhuis - Location Zwijndrecht

    Zwijndrecht, 3331 LZ

Other trials in Netherlands

China20 sites
  • Peking University First Hospital

    Beijing, 100034

  • The First Affiliated Hospital of Bengbu Medical College

    Bengbu, 233017

  • The First People's Hospital of Changde City

    Changde, 415003

  • The Second People's Hospital of Changzhou

    Changzhou, 213164

  • Affiliated Hospital of Chifeng University

    Chifeng, 24050

  • Daqing People's Hospital

    Daqing, 163711

  • Shunde Hospital of Southern Medical University

    Foshan, 528308

  • Guangdong Provincial People's Hospital

    Guangzhou, 510080

  • Heilongjiang Provincial Hospital

    Harbin, 150036

  • The First Affiliated Hospital of Nanyang Medical College - 2nd site

    Nanyang, 473024

  • The First affiliated Hospital of Nanyang Medical College

    Nanyang, 473024

  • Ningbo First Hospital

    Ningbo, 315010

  • Panjin Liaoyou Gem Flower Hospital

    Panjin, 124010

  • Pingxiang People's Hospital

    Pingxiang, 337055

  • People's Hospital of Tianjin

    Tianjin, 300121

  • Tianjin Fourth Central Hospital

    Tianjin, 300143

  • Xi'an Gaoxin Hospital

    Xi'an, 710075

  • Xianyang Hospital of Yan 'an University

    Xianyang, 712099

  • The Third Affiliatied Hospital of Xinxiang Medical University

    Xinxiang, 453000

  • Zibo City Linzi District People's Hospital

    Zibo, 255499

Other trials in China

Czechia20 sites
  • Hornicka nemocnice s poliklinikou Bilina s.r.o.

    Bílina, 41801

  • Medicus Services SRO

    Brandýs nad Labem, 250 01

  • Centrum pro zdravi - kardiologie s.r.o.

    Brno, 60300

  • Kardiologicka ambulance Brno s.r.o.

    Brno, 612 00

  • Amkardia sro

    Brno

  • Nemocnice Havlickuv Brod, p.o.

    Havlíčkův Brod

  • Cevni ambulance - MATMED s.r.o.

    Hodonín

  • MUDr. Tomas Edelsberger - diabetologicka ambulance

    Krnov

  • Lunacor s.r.o. - Centrum pro choroby srdce a cev

    Kroměříž, 767 01

  • KARDIOLOGIE - LIBEREC s.r.o.

    Liberec, 46014

  • InterKardio ML s.r.o.

    Mariánské Lázně, 353 01

  • Edumed s.r.o.

    Náchod, 551 01

  • PreventaMed s.r.o.

    Olomouc, 779 00

  • CCR Ostrava s.r.o.

    Ostrava, 702 00

  • Lunacor, s.r.o. - Centrum pro choroby srdce a cev - Otrokovice

    Otrokovice, 765 02

  • Kardiologie COR s.r.o.

    Prague, 106 00

  • Vseobecna fakultni nemocnice v Praze

    Prague, 128 08

  • Fakultní nemocnice v Motole

    Prague, 15006

  • Ustredni vojenska nemocnice

    Prague, 169 02

  • Krajska nemocnice T. Bati

    Zlín, 762 75

Other trials in Czechia

Georgia19 sites
  • Health Ltd

    Batumi

  • JSC Evex Hospitals - Batumi Referral Hospital

    Batumi

  • Kutaisi Primary Health Care Center #1

    Kutaisi

  • Bokhua Memorial Cardiovascular Center LTD

    Tbilisi

  • Cardioclinic Digomi Medical Center-

    Tbilisi

  • David Metreveli Medical Centre Lt

    Tbilisi

  • Emergency Cardiology Center by Academician G. Chapidze Ltd

    Tbilisi

  • JSC Curatio

    Tbilisi

  • LTD Adapti

    Tbilisi

  • Ltd Georgian-Dutch Hospital

    Tbilisi

  • LTD Israeli -Georgian Medical Research Clinic Healthycore

    Tbilisi

  • Ltd Tbilisi Heart Center

    Tbilisi

  • LTD Vitamed

    Tbilisi

  • Mediclub Georgia

    Tbilisi

  • Multiprofile Clinic Consilium Medulla LTD

    Tbilisi

  • National Center for Diabetes Research

    Tbilisi

  • Tbilisi Heart and Vascular Clinic Ltd

    Tbilisi

  • The First Medical Center LTD

    Tbilisi

  • VivaMedi

    Tbilisi

Other trials in Georgia

Canada18 sites
  • Brampton Clinical Trials

    Brampton

  • Ecogene-21

    Chicoutimi, Quebec, G7H 7K9

  • LMC Diabetes & Endocrinology Ltd. - Thornhill

    Concord, Ontario, L4K 4M2

  • Medical Arts Health Research Group - Kamloops

    Kamloops, British Columbia, V2C 5T1

  • Centre de recherche clinique de Laval

    Laval

  • KMH Cardiology & Diagnostic Centres - Mississauga

    Mississauga

  • Medical Arts Health Research Group - North Vancouver

    North Vancouver, British Columbia, V7M 2H4

  • Dr. James Cha

    Oshawa, Ontario, L1J2K1

  • The Medical Arts Health Research Group - Penticton

    Penticton, British Columbia, V2A 5L5

  • Kawartha Cardiology Clinical Trials

    Peterborough, Ontario, K9J 0B2

  • Institut Universitaire de Cardiologie et de Pneumologie De Quebec

    Québec

  • CardioVasc HR

    Saint-Jean-sur-Richelieu, Quebec, J3A 1J2

  • Centre intégré universitaire de santé et de services sociaux (CIUSSS) de l'Estrie -Centre hospitalier universitaire de Sherbrooke (CHUS)

    Sherbrooke, Quebec, J1H 5N4

  • KMH Cardiology & Diagnostic Centres - Hamilton

    Stoney Creek, Ontario, L8J 3W2

  • Diex Recherche Trois-Rivieres, Inc

    Trois-Rivières, Quebec, G9A 4P3

  • Discovery Clinical Services, Ltd

    Victoria

  • Diex Recherche Victoriaville

    Victoriaville, Quebec, G6P 6P6

  • Winnipeg Clinic

    Winnipeg, Manitoba, R3C 0N2

Other trials in Canada

Spain16 sites
  • Hospital Universitario de A Coruna

    A Coruña

  • Hospital General Universitario de Alicante Dr. Balmis

    Alicante

  • Hospital Universitario Torrecardenas

    Almería

  • Hospital del Mar

    Barcelona

  • Hospital Universitari de Bellvitge

    Barcelona

  • Hospital Universitario Vall d'Hebron

    Barcelona

  • Hospital Universitario Reina Sofia

    Córdoba

  • Hospital Universitario Virgen de las Nieves

    Granada

  • Hospital General Universitario Gregorio Maranon

    Madrid

  • Hospital Universitario Virgen de la Victoria

    Málaga

  • Hospital Clinico Universitario de Santiago

    Santiago de Compostela

  • Hospital Universitario Virgen Macarena

    Seville

  • Hospital Universitario Joan XXIII de Tarragona

    Tarragona

  • Hospital Clinico Universitario de Valencia

    Valencia

  • Hospital Alvaro Cunqueiro

    Vigo

  • Hospital Universitario Miguel Servet

    Zaragoza

Other trials in Spain

Australia15 sites
  • Royal Adelaide Hospital

    Adelaide

  • Flinders Medical Centre

    Bedford Park, 5042

  • Campbelltown Hospital

    Campbelltown

  • The Prince Charles Hospital

    Chermside, 4032

  • Monash Health

    Clayton, 3168

  • Bridge Family Practice

    Halls Creek, 6210

  • Austin Health

    Heidelberg, 3084

  • Baker Heart and Diabetes Institute

    Melbourne, VIC 3004

  • The Alfred Hospital

    Melbourne

  • Redcliffe Hospital

    Redcliffe, 4020

  • Western Health

    Saint Albans, VIC 3021

  • Griffith University

    Southport, 4222

  • Wollongong Hospital (Illawarra Shoalhaven Local Health District)

    Wollongong, 2500

  • The Queen Elizabeth Hospital (TQEH) - SA Health

    Woodville South

  • Dr Heart Pty Ltd at Cholesterol Care Australia

    Woolloongabba, 4102

Other trials in Australia

Israel14 sites
  • Barzilai Medical Center

    Ashkelon, 7830604

  • Bnai Zion Medical Center

    Haifa, 3104802

  • Rambam Health Care Campus

    Haifa, 3109601

  • The Lady Davis Carmel Medical Center

    Haifa, 3436212

  • Shaare Zedek Medical Center

    Jerusalem, 9103102

  • Hadassah Hebrew University Medical Center - Cardiology - The Heart Institute

    Jerusalem, 9112001

  • Meir Medical Center

    Kfar Saba, 44281

  • Galilee Medical Cente

    Nahariya, 2210001

  • Rabin Medical Center, Beilinson Hospital - Internal Medicine B

    Petah Tikva, 4941492

  • Rabin Medical Center, Beilinson Hospital

    Petah Tikva, 4941492

  • The BARUCH PADEH Medical Center, Poriya

    Poria – Neve Oved, 1520800

  • Kaplan Medical Center

    Rehovot, 7610001

  • Ziv Medical Center

    Safed, 1340305

  • Shamir Medical Center (Assaf Harofeh)

    Tsrifin, 6093000

Other trials in Israel

Italy7 sites
  • Azienda Ospedaliero-Universitaria di Ferrara-Arcispedale Sant'Anna

    Ferrara

  • IRCCS Ospedale San Raffaele

    Milan

  • Azienda Ospedaliera Universitaria Federico II

    Naples

  • Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone

    Palermo, 90127

  • Fondazione IRCCS Policlinico San Matteo

    Pavia, 27100

  • Istituto Clinico Humanitas

    Rozzano

  • Azienda Ospedaliera Santa Maria di Terni

    Terni

Other trials in Italy

South Africa7 sites
  • Iatros International

    Bloemfontein

  • Tiervlei Trial Centre (TTC)

    Cape Town

  • TREAD Research - Department of Cardiology

    Cape Town

  • WCR - Bara Cardiology

    Johannesburg, 2013

  • Dr JM Engelbrecht Trial Site

    Somerset West

  • Helderberg Research Institute

    Somerset West

  • Mediclinic Victoria

    Tongaat

Other trials in South Africa

Denmark6 sites
  • Aalborg University Hospital

    Aalborg, 9000

  • Bispebjerg Hospital

    Copenhagen, 2000

  • Amager Hospital

    Copenhagen, 2300

  • Sydvestjysk Hospital

    Esbjerg, 6700

  • Godstrup Regional Hospital (Gødstrup)

    Herning, 7400

  • Viborg Regional Hospital

    Viborg, 8800

Other trials in Denmark

Croatia5 sites
  • General Hospital Karlovac

    Karlovac, 47000

  • Special Hospital for Medical Rehabilitation Krapinske Toplice

    Krapinske Toplice, 49217

  • General Hospital Dr Josip Bencevic

    Slavonski Brod, 35000

  • Polyclinic Solmed

    Zagreb, 10000

  • University Hospital Center Zagreb

    Zagreb, 10000

Other trials in Croatia

Latvia5 sites
  • Latgales Medical Center

    Daugavpils, 5417

  • SIA ANIO

    Daugavpils

  • D. Saulites-Kandevicas Private Practice

    Liepāja

  • Pauls Stradins Clinical University Hospital Riga

    Riga, 1002

  • Vidzemes Hospital

    Valmiera, 4201

Other trials in Latvia

Jordan4 sites
  • Abdali Hospital

    Amman

  • Istishari Hospital

    Amman

  • Irbid Specialty Hospital

    Irbid

  • Pharmaceutical Research Center -Jordan University of Science & Technology/King Abdulla University Hospital - Cardiology

    Irbid

Other trials in Jordan

Finland3 sites
  • StudyCor Oy

    Jyväskylä, 40620

  • Satucon Oy Kuopio

    Kuopio

  • Turku University Hospital

    Turku, 20521

Other trials in Finland

About this study

Official title: Placebo Controlled, Double Blind, Randomized Cardiovascular Outcome Study to Evaluate the Effect of 10 mg Obicetrapib in Participants With ASCVD Not Adequately Controlled Despite Maximally Tolerated Lipid Modifying Therapies

This study will be a placebo-controlled, double-blind, randomized, phase 3 study in participants with Atherosclerotic Cardiovascular Disease (ASCVD) who are not adequately controlled despite maximally tolerated lipid-lowering therapy.

Read the detailed description

This study will be a placebo-controlled, double-blind, randomized, phase 3 study to evaluate the effect of 10mg Obicetrapib in participants with Atherosclerotic Cardiovascular Disease (ASCVD) who are not adequately controlled despite maximally tolerated lipid-lowering therapy to reduce the risk of cardiovascular death, myocardial infarction, stroke and non-elective coronary revascularization. The PREVAIL Study

Being tested
Obicetrapib, Placebo
Medical subject headings
Atherosclerosis

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • ObicetrapibDrug

    10mg obicetrapib tablet

  • PlaceboDrug

    Placebo tablet to resemble obicetrapib

Study groups in NCT05202509
Study groupRoleWhat they receive
obicetrapib 10mgExperimentalone 10mg tablet, once daily.
Receives: Drug: Obicetrapib
PlaceboPlacebo comparatorone placebo tablet, once daily
Receives: Drug: Placebo

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Major Adverse Cardiovascular Effect (MACE)

    To evaluate the effect of obicetrapib on the risk of MACE

    Measured: 30 months after last participant randomized

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted21 Jan 2022
  2. Study start7 Feb 2022
  3. Primary completionNov 2026 (estimated)
  4. Study completionNov 2026 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase 3
Primary purpose
Treatment
Allocation
Randomised
Intervention model
Parallel groups
Model description
Placebo-Controlled, Double-Blind, Randomized
Masking
Quadruple blind
Who is masked
Participant, Care provider, Investigator, Outcomes assessor
Enrolment
9,541 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT05202509
Sponsor's protocol ID
TA-8995-304
Acronym
PREVAIL
Status last verified
Jun 2024
First submitted
22 Nov 2021
Last updated
4 Jun 2024
Results posted
No
Data monitoring committee
Yes
FDA-regulated drug
Yes
FDA-regulated device
No
Individual data sharing
No

Questions about this trial

What is this clinical trial studying?

A Phase 3 study testing Obicetrapib in people with Atherosclerotic Cardiovascular Disease, run by NewAmsterdam Pharma at 591 sites in 23 countries.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 9 inclusion and 15 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: under way, not looking for participants, as of the sponsor's last update on 4 Jun 2024. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 591 sites in United States, Poland, Bulgaria, Germany, United Kingdom and 18 more countries. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

What does this phase mean?

Phase 3 studies compare the treatment with the current standard treatment or a placebo in a large group, to confirm how well it works and watch for side effects.

Not every study follows the same path, and some studies (observational studies, device studies) have no phase.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Major Adverse Cardiovascular Effect (MACE) (time frame: 30 months after last participant randomized). It is what the study was designed to measure, not a finding.

Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 4 Jun 2024.

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