Osteoarthritis, HipNCT05212090
Variability in Spinopelvic Parameters Among Patients Undergoing Total Hip Arthroplasty
A study testing EOS X-Ray in people with Osteoarthritis, Hip, run by Mayo Clinic at 1 site in United States.
Trial summary
This research is being conducted to assess measurement correlations on different X-ray views on patients who have undergone or will undergo hip reconstruction surgery. Read more about this study
- Who is it for?
- Ages 18 to 99 years
- Conditions the study is for
- Osteoarthritis, Hip
- What is being tested?
- EOS X-Ray
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- 1 siteUnited States
- Study dates
- 1 Feb 2022to 12 Mar 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 99 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Ability to provide informed consent.
- 40 patients: 20 preoperative THA, 20 postoperative THA;
- Sex: 20 men, 20 women;
- Age: 20 patients ≥ 70 years, 10 patients 50-70 years, 10 patients 18-50 years.
Who cannot join
- Patients with lumbosacral hardware, contralateral THA.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Study-Dependent Variability in Spinopelvic Parameters Among Patients Undergoing Total Hip Arthroplasty
This research is being conducted to assess measurement correlations on different X-ray views on patients who have undergone or will undergo hip reconstruction surgery.
- Conditions
- Osteoarthritis, Hip
- Being tested
- EOS X-Ray
- Medical subject headings
- Osteoarthritis, Hip
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
EOS X-RayDiagnostic test
Repeated Anteroposterior (AP) Pelvis x-ray and Lateral Lumbar EOS x-ray
| Study group | Role | What they receive |
|---|---|---|
| Pre-THA | Other | Subjects will be receiving EOS imaging prior to Total Hip Arthroplasty (THA) Receives: Diagnostic Test: EOS X-Ray |
| Post-THA | Other | Subjects will be receiving EOS imaging after Total Hip Arthroplasty (THA) Receives: Diagnostic Test: EOS X-Ray |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in pelvic incidence (PI)
Measured from EOS imaging and AP x-ray, reported in degrees
Measured: Baseline, 8 hours, 4 weeks
Change in symphysis to sacrococcygeal junction distance (PSCD)
Measured from EOS imaging and AP x-ray, reported in millimeters (mm)
Measured: Baseline, 8 hours, 4 weeks
Change in pelvic tilt (PT)
Measured from EOS imaging and AP x-ray, reported in degrees
Measured: Baseline, 8 hours, 4 weeks
Change in sacral slope (SS)
Measured from EOS imaging and AP x-ray, reported in degrees
Measured: Baseline, 8 hours, 4 weeks
Change in lumbar lordosis (LL)
Measured from EOS imaging and AP x-ray, reported in degrees
Measured: Baseline, 8 hours, 4 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted27 Jan 2022
- Study start1 Feb 2022
- Primary completion12 Mar 2025
- Study completion12 Mar 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Osteoarthritis, HipStudies of the same condition, open and under way.
- More trials run by Mayo ClinicThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Health services research
- Allocation
- Non-randomised
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 40 participants (actual)
Sponsor and investigators
- Lead sponsor
- Mayo Clinic
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Matthew P. Abdel, M.D., Mayo Clinic
- Investigators
- Matthew Abdel, MD, Principal investigator, Mayo Clinic
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05212090
- Sponsor's protocol ID
- 21-011655
- Status last verified
- Mar 2025
- First submitted
- 26 Jan 2022
- Last updated
- 17 Mar 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 17 Mar 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Study-Dependent Variability in Spinopelvic Parameters Among Patients Undergoing Total Hip Arthroplasty
- ClinicalTrials.gov ID
- NCT05212090
- Acronym / sponsor ID
- 21-011655
- Conditions
- Osteoarthritis, Hip
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 40 participants (actual)
- Lead sponsor
- Mayo ClinicUniversity, hospital or other
- Study start
- 1 Feb 2022 (actual)
- Primary completion
- 12 Mar 2025 (actual)
- Study completion
- 12 Mar 2025 (actual)
- First posted
- 27 Jan 2022 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This research is being conducted to assess measurement correlations on different X-ray views on patients who have undergone or will undergo hip reconstruction surgery.
Study design
- Primary purpose
- Health services research
- Allocation
- Non-randomised
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Pre-THA | Other | Diagnostic Test: EOS X-RaySubjects will be receiving EOS imaging prior to Total Hip Arthroplasty (THA) |
| Post-THA | Other | Diagnostic Test: EOS X-RaySubjects will be receiving EOS imaging after Total Hip Arthroplasty (THA) |
Who may qualify
- Ages
- 18 to 99 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Ability to provide informed consent.
- 40 patients: 20 preoperative THA, 20 postoperative THA;
- Sex: 20 men, 20 women;
- Age: 20 patients ≥ 70 years, 10 patients 50-70 years, 10 patients 18-50 years.
Key exclusion criteria (1 listed)
- Patients with lumbosacral hardware, contralateral THA.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| EOS X-RayRepeated Anteroposterior (AP) Pelvis x-ray and Lateral Lumbar EOS x-ray | Diagnostic test | Post-THA, Pre-THA |
Primary outcome
Change in pelvic incidence (PI)
Time frame: Baseline, 8 hours, 4 weeks
Measured from EOS imaging and AP x-ray, reported in degrees
Change in symphysis to sacrococcygeal junction distance (PSCD)
Time frame: Baseline, 8 hours, 4 weeks
Measured from EOS imaging and AP x-ray, reported in millimeters (mm)
Change in pelvic tilt (PT)
Time frame: Baseline, 8 hours, 4 weeks
Measured from EOS imaging and AP x-ray, reported in degrees
Change in sacral slope (SS)
Time frame: Baseline, 8 hours, 4 weeks
Measured from EOS imaging and AP x-ray, reported in degrees
Change in lumbar lordosis (LL)
Time frame: Baseline, 8 hours, 4 weeks
Measured from EOS imaging and AP x-ray, reported in degrees
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Mar 2025.
- Mayo Clinic Clinical TrialsLink provided by the sponsor.
Related trials for Osteoarthritis, Hip
Active, not recruiting
Effectiveness of Therapeutic Exercises on Spinopelvic Mobility
Osteoarthritis (OA) of the Hip
Recruiting
Intravenous Dexamethasone (0 vs 4 vs 8 mg) as an Adjunct to PENG Block for Postoperative Analgesia in Total Hip Arthroplasty
Osteoarthritis, Hip, Hip Osteoarthritis
Recruiting
Effects of EDUcation and EXercise Compared to Education Alone on Clinical and Physiological Outcomes in Patients With Hip Osteoarthritis
Hip Osteoarthritis
Recruiting
Comparison of Spinal Anesthesia With Intrathecal Morphine Versus PENG Block With or Without Dexamethasone in Hip Arthroplasty
Arthropathy of Hip, Hip Osteoarthritis
RecruitingPhase 4
PENG vs L-ESPB With S-ESPB for Analgesia in Total Hip Arthroplasty
Hip Osteoarthritis, Hip Arthropathy
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Matthew Abdel, MD principal investigator
Mayo Clinic
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing EOS X-Ray in people with Osteoarthritis, Hip, run by Mayo Clinic at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 17 Mar 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in pelvic incidence (PI) (time frame: Baseline, 8 hours, 4 weeks). The study lists 5 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Mar 2025; AzTrials last refreshed its copy on 6 Nov 2026.