Taste DisordersNCT05227157
GOUTMETALSAIN: Comparison of the Perception of Metallic Taste According to Lingual Locations in Healthy Volunteers
An observational study of Taste Disorders and Sensation Disorders, run by Centre Hospitalier de Valence at 1 site in France.
Trial summary
This is a mono center , observational study carried out within otorhinolaryngology department in CH Valence. This is a descriptive and exploratory study in healthy volunteers. Based on the hypothesis that Metallic taste is imperfectly assessed, this study will provide a better understanding of the Metallic Taste. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Taste Disorders, Sensation Disorders, Taste, Metallic
- What is being tested?
- swab with iron sulfate solution
- How many people
- 60 participants
- Where
- 1 siteFrance
- Study dates
- 15 Dec 2021to 1 May 2022
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: healthy volonteers without olfactory and gustatory disorder
Who may be able to join
- Age ≥ 18 years old
- Healthy volunteers
- Read, write and understand the French language
- Patient affiliated to a social security system
- Written and signed informed consent
Who cannot join
- head and Neck cancer history
- olfactory and gustatory disorder
- Refusal to participate in research
- Patient under guardianship, deprived of liberty, safeguard of justice
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Comparison of the Perception of Metallic Taste According to Lingual Locations in Healthy Volunteers
This is a mono center , observational study carried out within otorhinolaryngology department in CH Valence.
This is a descriptive and exploratory study in healthy volunteers. Based on the hypothesis that Metallic taste is imperfectly assessed, this study will provide a better understanding of the Metallic Taste.
Read the detailed description
The study consists of the application of a swab soaked in iron sulfate at a concentration of 10g/l.
each patient will rate the intensity he/she perceives (on a numerical scale from 1 to 5) at each of the 4 predefined lingual locations
- Conditions
- Taste Disorders, Sensation Disorders, Taste, Metallic, Taste Disorder, Glossopharyngeal Nerve
- Being tested
- swab with iron sulfate solution
- Keywords
- Taste, Metallic
- Medical subject headings
- Taste Disorders, Sensation Disorders, Glossopharyngeal Nerve Diseases
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
swab with iron sulfate solutionOther
measurement of the intensity of perception of metallic taste by affixing a swab iron sulfate solution 10g/l at 4 places on the tongue depending on the glossopharyngeal nerve: tip of the tongue (right and left); base of the tongue (right and left). Visual analogic Scale (0 to 5)
| Study group | Role | What they receive |
|---|---|---|
| 1: intensity of perception of metallic taste | For this study, there is only one arm: swab with iron sulfate solution at a concentration of 10g/l.
Each subject complete visual scale Receives: Other: swab with iron sulfate solution |
What is being measured
The primary outcome is the main question the study is designed to answer.
evaluation of the intensity of metallic taste
visual analogue scale (0 to 5); A score of 5 means the highest intensity of metallic taste
Measured: 5 minutes
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted7 Feb 2022
- Study start15 Dec 2021
- Primary completion8 Apr 2022
- Study completion1 May 2022
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Taste DisordersStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 60 participants (actual)
Sponsor and investigators
- Lead sponsor
- Centre Hospitalier de Valence
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05227157
- Sponsor's protocol ID
- RIPH-CHV-10
- Status last verified
- Sep 2025
- First submitted
- 26 Jan 2022
- Last updated
- 8 Sep 2025
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 8 Sep 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of the Perception of Metallic Taste According to Lingual Locations in Healthy Volunteers
- ClinicalTrials.gov ID
- NCT05227157
- Acronym / sponsor ID
- RIPH-CHV-10
- Conditions
- Taste Disorders, Sensation Disorders, Taste, Metallic, Taste Disorder, Glossopharyngeal Nerve
- Keywords
- Taste, Metallic
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 60 participants (actual)
- Lead sponsor
- Centre Hospitalier de ValenceUniversity, hospital or other
- Study start
- 15 Dec 2021 (actual)
- Primary completion
- 8 Apr 2022 (actual)
- Study completion
- 1 May 2022 (actual)
- First posted
- 7 Feb 2022 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This is a mono center , observational study carried out within otorhinolaryngology department in CH Valence.
This is a descriptive and exploratory study in healthy volunteers. Based on the hypothesis that Metallic taste is imperfectly assessed, this study will provide a better understanding of the Metallic Taste.
Detailed description
The study consists of the application of a swab soaked in iron sulfate at a concentration of 10g/l.
each patient will rate the intensity he/she perceives (on a numerical scale from 1 to 5) at each of the 4 predefined lingual locations
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| 1: intensity of perception of metallic taste | – | Other: swab with iron sulfate solutionFor this study, there is only one arm: swab with iron sulfate solution at a concentration of 10g/l. Each subject complete visual scale |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- healthy volonteers without olfactory and gustatory disorder
Key inclusion criteria (5 listed)
- Age ≥ 18 years old
- Healthy volunteers
- Read, write and understand the French language
- Patient affiliated to a social security system
- Written and signed informed consent
Key exclusion criteria (4 listed)
- head and Neck cancer history
- olfactory and gustatory disorder
- Refusal to participate in research
- Patient under guardianship, deprived of liberty, safeguard of justice
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| swab with iron sulfate solutionmeasurement of the intensity of perception of metallic taste by affixing a swab iron sulfate solution 10g/l at 4 places on the tongue depending on the glossopharyngeal nerve: tip of the tongue (right and left); base of the tongue (right and left). Visual analogic Scale (0 to 5) | Other | 1: intensity of perception of metallic taste |
Primary outcome
evaluation of the intensity of metallic taste
Time frame: 5 minutes
visual analogue scale (0 to 5); A score of 5 means the highest intensity of metallic taste
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 8 Sep 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Taste Disorders and Sensation Disorders, run by Centre Hospitalier de Valence at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 8 Sep 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
evaluation of the intensity of metallic taste (time frame: 5 minutes). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Sep 2025.