Self-PerceptionSINOVE-PRONCT05238285
Production of Nonverbal Acoustic Signals and Resulting Physiological Responses
An observational study of Self-Perception, run by Centre Hospitalier Universitaire de Saint Etienne at 1 site in France.
Trial summary
Like many other animals, humans produce nonverbal vocal signals including screams, grunts, roars, cries and laughter across a variety of contexts. However, despite their importance in the human vocal repertoire, the mechanisms and functions of non-verbal signals remain little studied and poorly understood in… Read more about this study
- Who is it for?
- Ages 18 to 80 yearsHealthy volunteers can take part
- Conditions the study is for
- Self-Perception
- What is being tested?
- Production of vocal sounds
- Type of treatment
- Lifestyle or therapy programme
- How many people
- 2,000 participants
- Where
- 1 siteFrance
- Study dates
- 8 Mar 2023to Apr 2027
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 80 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: Healthy adult population aged 18 to 80 years
Who may be able to join
- Participant should be affiliated or entitled to a social security scheme
Who cannot join
- Pregnant women
- Voice production disorders
- Hearing impairment, speech production disorders or major health problems.
- Chronic smoker (more than 10 cigarettes per day)
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
France1 site, 1 recruiting
- Recruiting
Centre Hospitalier Universitaire de Saint-Etienne
Saint-Etienne, 42055
David REBY, MDPHD
Nicolas MATHEVON, MDPHD
About this study
Like many other animals, humans produce nonverbal vocal signals including screams, grunts, roars, cries and laughter across a variety of contexts. However, despite their importance in the human vocal repertoire, the mechanisms and functions of non-verbal signals remain little studied and poorly understood in humans.Our studies aim to improve our understanding of the nature and function of non-verbal signals.
Read the detailed description
Like many other animals, humans produce nonverbal vocal signals including screams, grunts, roars, cries and laughter across a variety of contexts. Many of these signals (such as cries) are already produced at birth and likely serve a number of important biological and social functions. In addition, human speech is characterised by nonlinguistic acoustic parameters (such as pitch, formant frequencies, and nonlinear phenomena) that are known to correlate with biologically important traits of the vocalizer.
However, despite their importance in the human vocal repertoire, the mechanisms and functions of non-verbal signals remain little studied and poorly understood in humans.
Theses studies aim to improve the understanding of the nature and function of non-verbal signals. Thus, this study is part of a long-term research project in which investigators are trying to clarify the information contained in the acoustic structure of human non-verbal signals, and to investigate the factors influencing their production.
- Conditions
- Self-Perception
- Being tested
- Production of vocal sounds
- Keywords
- acoustic analysis, physiological responses, psycho-acoustic tests
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Production of vocal soundsBehavioural
Participants will be asked to produce vocal sounds of different nature according to the non-verbal parameters of interest for the given study.
For example, they can read a script containing vowels ('a', 'e', 'i', 'o', 'u'), short sentences ('hello, how are you'), longer passages of standardised reading texts, and can also be asked to speak freely about any topic ('freedom of speech'). They can be asked to play a role or to imitate a particular emotional state. For example, "imagine that you have just been told that you have won a million euros in the lottery. Produce a vocalisation to express your excitement" or "talk to your dog your dog by imagining that he has done a negative action and then do the same thing by imagining that this time imagining that the action was positive".
| Study group | Role | What they receive |
|---|---|---|
| Healthy adult population aged 18 to 80 years | Participants will be asked to produce vocal sounds of different nature according to the non-verbal parameters of interest for the given study. Receives: Behavioral: Production of vocal sounds |
What is being measured
The primary outcome is the main question the study is designed to answer.
Vocal analysis
Participants will receive instructions on what to say or what type of non-verbal vocalisation to produce during the manipulation.
The vocalisations thus produced by the participants will be systematically recorded and analysed using software adapted to acoustic analysis
Measurement of acoustic variables such as fundamental frequency (pitch), vocal tract resonances (formants) and vocal disturbances (jitter, shimmer), the nonlinearities and chaotic/noise properties of vocalisations
Measured: During the vocal production
Secondary outcomes (5)
Heart rate (bpm)
Measured: During the vocal production
Skin conductance (Siemens)
Measured: During the vocal production
Skin temperature (°C)
Measured: During the vocal production
Nociception Level Index (NOL)
A non-invasive finger probe, containing four sensors, will be placed on the on the index finger of the participants.
Measured: During the vocal production
Pupillary diameter (millimeter)
Using a high resolution binocular for automated pupil diameter measurement with an infrared camera
Measured: During the vocal production
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 Feb 2022
- Study start8 Mar 2023
- Primary completionApr 2027 (estimated)
- Study completionApr 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Self-PerceptionStudies of the same condition, open and under way.
- More trials run by Centre Hospitalier Universitaire de Saint EtienneThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Prospective
- Enrolment
- 2,000 participants (estimated)
Sponsor and investigators
- Sponsor type
- University, hospital or other
- Collaborators
- University of Lyon
- Responsible party
- Sponsor
- Investigators
- ROLAND PEYRON, MDPHD, Principal investigator, Centre Hospitalier Universitaire de Saint EtienneNicolas MATHEVON, PhD, Study director, University of Saint-Etienne, France
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05238285
- Sponsor's protocol ID
- 20CH259
- Other IDs
- 2020-A03457-32:
- Acronym
- SINOVE-PRO
- Status last verified
- May 2026
- First submitted
- 2 Feb 2022
- Last updated
- 6 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 6 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Production of Nonverbal Acoustic Signals and Resulting Physiological Responses
- ClinicalTrials.gov ID
- NCT05238285
- Acronym / sponsor ID
- SINOVE-PRO / 20CH259
- Conditions
- Self-Perception
- Keywords
- acoustic analysis, physiological responses, psycho-acoustic tests
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 2,000 participants (estimated)
- Lead sponsor
- Centre Hospitalier Universitaire de Saint EtienneUniversity, hospital or other
- Collaborators
- University of Lyon
- Study start
- 8 Mar 2023 (actual)
- Primary completion
- Apr 2027 (estimated)
- Study completion
- Apr 2027 (estimated)
- First posted
- 14 Feb 2022 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Like many other animals, humans produce nonverbal vocal signals including screams, grunts, roars, cries and laughter across a variety of contexts. However, despite their importance in the human vocal repertoire, the mechanisms and functions of non-verbal signals remain little studied and poorly understood in humans.Our studies aim to improve our understanding of the nature and function of non-verbal signals.
Detailed description
Like many other animals, humans produce nonverbal vocal signals including screams, grunts, roars, cries and laughter across a variety of contexts. Many of these signals (such as cries) are already produced at birth and likely serve a number of important biological and social functions. In addition, human speech is characterised by nonlinguistic acoustic parameters (such as pitch, formant frequencies, and nonlinear phenomena) that are known to correlate with biologically important traits of the vocalizer.
However, despite their importance in the human vocal repertoire, the mechanisms and functions of non-verbal signals remain little studied and poorly understood in humans.
Theses studies aim to improve the understanding of the nature and function of non-verbal signals. Thus, this study is part of a long-term research project in which investigators are trying to clarify the information contained in the acoustic structure of human non-verbal signals, and to investigate the factors influencing their production.
Study design
- Observational model
- Other
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Healthy adult population aged 18 to 80 years | – | Behavioral: Production of vocal soundsParticipants will be asked to produce vocal sounds of different nature according to the non-verbal parameters of interest for the given study. |
Who may qualify
- Ages
- 18 to 80 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- Healthy adult population aged 18 to 80 years
Key inclusion criteria (1 listed)
- Participant should be affiliated or entitled to a social security scheme
Key exclusion criteria (4 listed)
- Pregnant women
- Voice production disorders
- Hearing impairment, speech production disorders or major health problems.
- Chronic smoker (more than 10 cigarettes per day)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Production of vocal soundsParticipants will be asked to produce vocal sounds of different nature according to the non-verbal parameters of interest for the given study. For example, they can read a script containing vowels ('a', 'e', 'i', 'o', 'u'), short sentences ('hello, how are you'), longer passages of standardised reading texts, and can also be asked to speak freely about any topic ('freedom of speech'). They can be asked to play a role or to imitate a particular emotional state. For example, "imagine that you have just been told that you have won a million euros in the lottery. Produce a vocalisation to express your excitement" or "talk to your dog your dog by imagining that he has done a negative action and then do the same thing by imagining that this time imagining that the action was positive". | Behavioural | Healthy adult population aged 18 to 80 years |
Primary outcome
Vocal analysis
Time frame: During the vocal production
Participants will receive instructions on what to say or what type of non-verbal vocalisation to produce during the manipulation. The vocalisations thus produced by the participants will be systematically recorded and analysed using software adapted to acoustic analysis Measurement of acoustic variables such as fundamental frequency (pitch), vocal tract resonances (formants) and vocal disturbances (jitter, shimmer), the nonlinearities and chaotic/noise properties of vocalisations
5 secondary outcomes
Heart rate (bpm)
Time frame: During the vocal production
Skin conductance (Siemens)
Time frame: During the vocal production
Skin temperature (°C)
Time frame: During the vocal production
Nociception Level Index (NOL)
Time frame: During the vocal production
Pupillary diameter (millimeter)
Time frame: During the vocal production
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 May 2026.
- Individual participant dataSharing planned: No
Related trials for Self-Perception
Not yet recruiting
Study to Evaluate Xtressé Gummy Supplement in Women With Thinning Hair
Androgenetic Alopecia
RecruitingObservational study
Improved Facial Skin Quality and Quality of Life After VYC-12L Treatment in Breast Cancer Survivors
Quality of Life, Breast Neoplasms
Not yet recruiting
Genital Self İmage and Satisfaction With Genital Appearance
Women
Recruiting
Prenatal Yoga Intervention in Pregnant Women
Pregnant Women, Prenatal Yoga
Not yet recruitingObservational study
Perception of Action Opportunities for Obstacle Crossing in Parkinson's Disease
PARKINSON DISEASE (Disorder), Older Adults (65-85 Years)
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
ROLAND PEYRON, MDPHD principal investigator
Centre Hospitalier Universitaire de Saint Etienne
Nicolas MATHEVON, PhD study director
University of Saint-Etienne, France
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Self-Perception, run by Centre Hospitalier Universitaire de Saint Etienne at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 6 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact ROLAND PEYRON, MDPhD ((0)477127805 ext. +33, roland.peyron@chu-st-etienne.fr), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Vocal analysis (time frame: During the vocal production). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 May 2026.