ADHDTDAH-DRMNCT05365295
Study of ADHD Children's Sensitivity to Memory Error Production
A study testing DRM (Deese, Roediger et McDermott task) in people with ADHD, run by University Hospital, Angers at 2 sites in France.
Trial summary
The purpose of the study is to test whether children with Attention Deficit/Hyperactivity Disorder (ADHD) are more susceptible to false memory production using a DRM paradigm. The number of "critical decoy production" errors will be analyzed and compared to the calibration of the test. Read more about this study
- Who is it for?
- Ages 8 to 11 years
- Conditions the study is for
- ADHD
- What is being tested?
- DRM (Deese, Roediger et McDermott task)
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 28 participants
- Where
- 2 sitesFrance
- Study dates
- 28 Jun 2022to 17 Oct 2022
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 8 to 11 years
- All sexes
- No healthy volunteers
- Child
Who may be able to join
- Age between 96 and 131 months
- Child referred by a doctor for a neuropsychological assessment
- Child with ADHD diagnosis
- Sufficient command of the French language
- Non-opposition of the child and his/her parents
Who cannot join
- Severe psychiatric comorbidity: major depressive episode, bipolar disorder, generalized anxiety disorder, autism spectrum disorder
- Major neurological history: severe head trauma, stroke, severe epilepsy, brain tumor
- Repeating a class during school
- Presence of an intellectual disability
- Use of methylphenidate treatment less than 48 hours before the experiment
- Completion of an intellectual assessment using the Wechsler Intelligence Scale for Children (WISC-V) dated less than one year before the meeting
Trial locations and contacts
2 sites in 1 country.
France2 sites
neuropediatrics department - university hospital center of Angers
Angers
Multidisciplinary liberal practice - Acropole Santé
Rezé
About this study
Official title: Sensitivity of Children With Attention Deficit/Hyperactivity Disorder to Memory Error Production
The purpose of the study is to test whether children with Attention Deficit/Hyperactivity Disorder (ADHD) are more susceptible to false memory production using a DRM paradigm. The number of "critical decoy production" errors will be analyzed and compared to the calibration of the test.
Read the detailed description
During a neuropsychological assessment, as part of the clinical routine, children with a diagnosis of ADHD, without neurological etiology, aged 8 to 10 years will be offered an additional task. This task, a DRM adapted to the child, consists of learning several lists of words. Each list exposes words belonging to the same lexical field, to a concept not explicitly mentioned in the list, called critical lure. Immediately after the presentation of a list, the child is asked to recall as many words as possible. Recall of the critical lure gives an indication of the production of false memories. The number of critical lures produced by these children will be compared to the calibration of the test, currently being published. The investigator will also verify if the production of critical lures can be correlated with other variables such as performance on intellectual, executive and attentional tasks, proposed during the clinical routine assessment.
The investigator hypothesize that ADHD children will recall more critical lures than the norm, and fewer correct responses than the norm.
The data collected is taken from the child's psychological file. The only personal information used, beyond test performance, is the child's gender and age. The procedure is anonymous.
- Conditions
- ADHD
- Being tested
- DRM (Deese, Roediger et McDermott task)
- Medical subject headings
- Attention Deficit Disorder with Hyperactivity
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
DRM (Deese, Roediger et McDermott task)Other
Eight lists of nine words are presented to the participants. Each list is heard once. Immediately afterwards, the child is asked to recall the words he or she remembers. Each child's response is then repeated one by one and the participant is asked to rate his or her confidence in the response on a five-point scale (from "not at all sure" to "100% sure"). A 5-minute break is given in the middle of the task, after the first four lists are presented. The test takes about 20 minutes.
| Study group | Role | What they receive |
|---|---|---|
| ADHD | Experimental | - ADHD children aged between 8 to 10 years old Receives: Other: DRM (Deese, Roediger et McDermott task) |
What is being measured
The primary outcome is the main question the study is designed to answer.
DRM (Deese-Roediger-McDermott task) Performance 1
correct answers
Measured: 20 minutes during DRM DRM (Deese-Roediger-McDermott) task
DRM (Deese-Roediger-McDermott task) Performance 2
critical lures
Measured: 20 minutes during DRM DRM (Deese-Roediger-McDermott) task
DRM (Deese-Roediger-McDermott task) Performance 3
intruders associated with the lexical field
Measured: 20 minutes during DRM DRM (Deese-Roediger-McDermott) task
DRM (Deese-Roediger-McDermott task) Performance 4
non-associated intruders
Measured: 20 minutes during DRM DRM (Deese-Roediger-McDermott) task
DRM (Deese-Roediger-McDermott task) Performance 5
average confidence index for each type of answer
Measured: 20 minutes during DRM DRM (Deese-Roediger-McDermott) task
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted9 May 2022
- Study start28 Jun 2022
- Primary completion17 Oct 2022
- Study completion17 Oct 2022
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for ADHDStudies of the same condition, open and under way.
- More trials run by University Hospital, AngersThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Screening
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 28 participants (actual)
Sponsor and investigators
- Lead sponsor
- University Hospital, Angers
- Sponsor type
- Other government
- Responsible party
- Sponsor
- Investigators
- Pierre Martin, Principal investigator, UH Angers
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05365295
- Sponsor's protocol ID
- 49RC22-0095
- Acronym
- TDAH-DRM
- Status last verified
- Sep 2025
- First submitted
- 5 Apr 2022
- Last updated
- 19 Sep 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: Data will be shared upon reasonable request. Only de-identified data will be shared. Any data collected during the study may be shared. The protocol will be shared initially. Other documents may be shared at a later date upon request (e.g., the CRF to allow a collaborator to select the data they wish to access). The recipients of the data will be researchers. The data will be available for any purpose deemed relevant by the study investigator, based on a protocol provided by the requester, after verification of the obtaining of regulatory approvals, including the favorable opinion of an ethics committee.
Study at a glance
From the registry record, last updated by the sponsor on 19 Sep 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Sensitivity of Children With Attention Deficit/Hyperactivity Disorder to Memory Error Production
- ClinicalTrials.gov ID
- NCT05365295
- Acronym / sponsor ID
- TDAH-DRM / 49RC22-0095
- Conditions
- ADHD
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 28 participants (actual)
- Lead sponsor
- University Hospital, AngersOther government
- Study start
- 28 Jun 2022 (actual)
- Primary completion
- 17 Oct 2022 (actual)
- Study completion
- 17 Oct 2022 (actual)
- First posted
- 9 May 2022 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of the study is to test whether children with Attention Deficit/Hyperactivity Disorder (ADHD) are more susceptible to false memory production using a DRM paradigm. The number of "critical decoy production" errors will be analyzed and compared to the calibration of the test.
Detailed description
During a neuropsychological assessment, as part of the clinical routine, children with a diagnosis of ADHD, without neurological etiology, aged 8 to 10 years will be offered an additional task. This task, a DRM adapted to the child, consists of learning several lists of words. Each list exposes words belonging to the same lexical field, to a concept not explicitly mentioned in the list, called critical lure. Immediately after the presentation of a list, the child is asked to recall as many words as possible. Recall of the critical lure gives an indication of the production of false memories. The number of critical lures produced by these children will be compared to the calibration of the test, currently being published. The investigator will also verify if the production of critical lures can be correlated with other variables such as performance on intellectual, executive and attentional tasks, proposed during the clinical routine assessment.
The investigator hypothesize that ADHD children will recall more critical lures than the norm, and fewer correct responses than the norm.
The data collected is taken from the child's psychological file. The only personal information used, beyond test performance, is the child's gender and age. The procedure is anonymous.
Study design
- Primary purpose
- Screening
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| ADHD | Experimental | Other: DRM (Deese, Roediger et McDermott task)- ADHD children aged between 8 to 10 years old |
Who may qualify
- Ages
- 8 to 11 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child
Key inclusion criteria (5 listed)
- Age between 96 and 131 months
- Child referred by a doctor for a neuropsychological assessment
- Child with ADHD diagnosis
- Sufficient command of the French language
- Non-opposition of the child and his/her parents
Key exclusion criteria (6 listed)
- Severe psychiatric comorbidity: major depressive episode, bipolar disorder, generalized anxiety disorder, autism spectrum disorder
- Major neurological history: severe head trauma, stroke, severe epilepsy, brain tumor
- Repeating a class during school
- Presence of an intellectual disability
- Use of methylphenidate treatment less than 48 hours before the experiment
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| DRM (Deese, Roediger et McDermott task)Eight lists of nine words are presented to the participants. Each list is heard once. Immediately afterwards, the child is asked to recall the words he or she remembers. Each child's response is then repeated one by one and the participant is asked to rate his or her confidence in the response on a five-point scale (from "not at all sure" to "100% sure"). A 5-minute break is given in the middle of the task, after the first four lists are presented. The test takes about 20 minutes. | Other | ADHD |
Primary outcome
DRM (Deese-Roediger-McDermott task) Performance 1
Time frame: 20 minutes during DRM DRM (Deese-Roediger-McDermott) task
correct answers
DRM (Deese-Roediger-McDermott task) Performance 2
Time frame: 20 minutes during DRM DRM (Deese-Roediger-McDermott) task
critical lures
DRM (Deese-Roediger-McDermott task) Performance 3
Time frame: 20 minutes during DRM DRM (Deese-Roediger-McDermott) task
intruders associated with the lexical field
DRM (Deese-Roediger-McDermott task) Performance 4
Time frame: 20 minutes during DRM DRM (Deese-Roediger-McDermott) task
non-associated intruders
DRM (Deese-Roediger-McDermott task) Performance 5
Time frame: 20 minutes during DRM DRM (Deese-Roediger-McDermott) task
average confidence index for each type of answer
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 Sep 2025.
- Individual participant dataSharing planned: Yes. Data will be shared upon reasonable request. Only de-identified data will be shared. Any data collected during the study may be shared. The protocol will be shared initially. Other documents may be shared at a later date upon request (e.g., the CRF to allow a collaborator to select the data they wish to access). The recipients of the data will be researchers. The data will be available for any purpose deemed relevant by the study investigator, based on a protocol provided by the requester, after verification of the obtaining of regulatory approvals, including the favorable opinion of an ethics committee.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Pierre Martin principal investigator
UH Angers
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing DRM (Deese, Roediger et McDermott task) in people with ADHD, run by University Hospital, Angers at 2 sites in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 19 Sep 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
DRM (Deese-Roediger-McDermott task) Performance 1 (time frame: 20 minutes during DRM DRM (Deese-Roediger-McDermott) task). The study lists 5 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 Sep 2025.