Urinary Incontinence, UrgeMOVEONUPNCT05375344
Mobility and Voiding Exercises in Older Women With Urinary Incontinence (MoVEonUp)
A study testing Exercise Group in people with Urinary Incontinence, Urge, run by University of Pennsylvania at 1 site in United States.
Trial summary
A prospective, two-arm randomized clinical trial utilizing a multidimensional intervention to reduce falls in older women with Urinary Urge Incontinence. The intervention consist of general balance and strength training, bladder training and urge suppression, and home hazard assessments. Read more about this study
- Who is it for?
- Ages 70 years and older, women only
- Conditions the study is for
- Urinary Incontinence, Urge
- What is being tested?
- Exercise Group
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 375 participants
- Where
- 1 siteUnited States
- Study dates
- 9 Jun 2022to Oct 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 70 years and older
- Women only
- No healthy volunteers
- Older adult
Who may be able to join
- Female
- 70 or older
- Living independently in the community
- Willingness to be randomized.
- Ability to read and understand English
- Be able to provide informed consent
Show all 11Show fewer
- Low physical activity (physically active for 30 minutes or more less than or equal to 2 days per week on average over the past 6 months) per PAS
- Ambulatory (defined as patient not confined to bed or wheelchair OR ability to walk with or without an assistive device)
- Self-reported moderate to severe urge-predominant UI based on the ICIQ-SF > 6 (Q 1+2+3)
- Not planning to initiate new UI or overactive bladder (OAB) treatment during the study duration
- Capable of participation in an exercise program without exacerbating any pre-existing condition(s), as determined by the study PI or designee
Who cannot join
- Pelvic organ prolapse passed the hymen (per patient report)
- Undergoing active treatment for cancer (other than non-melanoma skin cancer)
- Uncorrected visual or hearing loss.
- Other urinary conditions or procedures that may affect continence status for example: urethral diverticulum, previous augmentation cystoplasty
- Progressive neurodegenerative disease e.g. Parkinson's disease, multiple sclerosis per patient report
- History of stroke or carotid sensitivity (i.e. syncopal falls) per patient report
Show all 10Show fewer
- Unstable cardiac disease per patient report
- Fracture or joint replacement within the last six months per patient report
- Significant cognitive impairment (defined as a modified TICs score of < 27)
- Per PI discretion, participant cannot enroll in study
Trial locations and contacts
1 site in 1 country.
United States1 site
University of Pennsylvania
Philadelphia, Pennsylvania, 19104
About this study
Official title: MoVE on Up: Mobility and Voiding Exercises in Older Women With Urinary Incontinence
A prospective, two-arm randomized clinical trial utilizing a multidimensional intervention to reduce falls in older women with Urinary Urge Incontinence. The intervention consist of general balance and strength training, bladder training and urge suppression, and home hazard assessments. The control group will receive informational booklets on fall prevention and behavioral treatment for urinary urge incontinence.
- Conditions
- Urinary Incontinence, Urge
- Being tested
- Exercise Group
- Medical subject headings
- Urinary Incontinence, Urge
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Exercise GroupBehavioural
Home-based exercise group intervention
| Study group | Role | What they receive |
|---|---|---|
| Exercise Group | Active comparator | Participants in this group will participate in the home-based exercise group intervention that consists of general balance and strength training, bladder training and urge suppression, and home hazard assessments. Receives: Behavioral: Exercise Group |
| Control Group | No intervention | Participants in this group will receive informational booklets on fall prevention and behavioral treatment for Urgency Incontinence. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in number of falls between the baseline visit and 1 year
number of falls reported in a falls diary
Measured: 12 months
Secondary outcomes (1)
Change in urinary incontinence score on the International Consultation on Incontinence Questionnaire Short Form (ICIQ-SF) between baseline visit and 1 year
Change in International Consultation on Incontinence Questionnaire Short Form (ICIQ-SF). A minimum score is 0, a maximum score is 21 with a higher score indicating higher severity.
Measured: 12 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted16 May 2022
- Study start9 Jun 2022
- Primary completionOct 2026 (estimated)
- Study completionOct 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Urinary Incontinence, UrgeStudies of the same condition, open and under way.
- More trials run by University of PennsylvaniaThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 375 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Pennsylvania
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Uduak Andy, University of Pennsylvania
- Investigators
- Uduak U Andy, MD, Principal investigator, University of Pennsylvania
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05375344
- Sponsor's protocol ID
- 849788
- Acronym
- MOVEONUP
- Status last verified
- Oct 2026
- First submitted
- 10 May 2022
- Last updated
- 14 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Andy UU, Newman DK, Wyman JF, Klusaritz H, Walsh W, Shou H, Koepler N, Schmitz KH, Reaves S, Arya L, Brown RT. The Mobility and Voiding Exercises in Older Women with Urinary Incontinence (MoVEonUp) randomized controlled trial: study protocol and rationale. BMC Geriatr. 2024 Dec 4;24(1):994. doi: 10.1186/s12877-024-05552-7.
PubMed 39633261
Study at a glance
From the registry record, last updated by the sponsor on 14 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- MoVE on Up: Mobility and Voiding Exercises in Older Women With Urinary Incontinence
- ClinicalTrials.gov ID
- NCT05375344
- Acronym / sponsor ID
- MOVEONUP / 849788
- Conditions
- Urinary Incontinence, Urge
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 375 participants (estimated)
- Lead sponsor
- University of PennsylvaniaUniversity, hospital or other
- Study start
- 9 Jun 2022 (actual)
- Primary completion
- Oct 2026 (estimated)
- Study completion
- Oct 2026 (estimated)
- First posted
- 16 May 2022 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
A prospective, two-arm randomized clinical trial utilizing a multidimensional intervention to reduce falls in older women with Urinary Urge Incontinence. The intervention consist of general balance and strength training, bladder training and urge suppression, and home hazard assessments. The control group will receive informational booklets on fall prevention and behavioral treatment for urinary urge incontinence.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Exercise Group | Active comparator | Behavioral: Exercise GroupParticipants in this group will participate in the home-based exercise group intervention that consists of general balance and strength training, bladder training and urge suppression, and home hazard assessments. |
| Control Group | No intervention | –Participants in this group will receive informational booklets on fall prevention and behavioral treatment for Urgency Incontinence. |
Who may qualify
- Ages
- 70 years and older
- Sex
- Female only
- Healthy volunteers
- Not accepted
- Age groups
- Older adult
Key inclusion criteria (11 listed)
- Female
- 70 or older
- Living independently in the community
- Willingness to be randomized.
- Ability to read and understand English
Key exclusion criteria (10 listed)
- Pelvic organ prolapse passed the hymen (per patient report)
- Undergoing active treatment for cancer (other than non-melanoma skin cancer)
- Uncorrected visual or hearing loss.
- Other urinary conditions or procedures that may affect continence status for example: urethral diverticulum, previous augmentation cystoplasty
- Progressive neurodegenerative disease e.g. Parkinson's disease, multiple sclerosis per patient report
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Exercise GroupHome-based exercise group intervention | Behavioural | Exercise Group |
Primary outcome
Change in number of falls between the baseline visit and 1 year
Time frame: 12 months
number of falls reported in a falls diary
1 secondary outcome
Change in urinary incontinence score on the International Consultation on Incontinence Questionnaire Short Form (ICIQ-SF) between baseline visit and 1 year
Time frame: 12 months
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 14 Oct 2026.
- Derived from this study: PubMed 39633261Andy UU, Newman DK, Wyman JF, Klusaritz H, Walsh W, Shou H, Koepler N, Schmitz KH, Reaves S, Arya L, Brown RT. The Mobility and Voiding Exercises in Older Women with Urinary Incontinence (MoVEonUp) randomized controlled trial: study protocol and rationale. BMC Geriatr. 2024 Dec 4;24(1):994. doi: 10.1186/s12877-024-05552-7.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Uduak U Andy, MD principal investigator
University of Pennsylvania
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Exercise Group in people with Urinary Incontinence, Urge, run by University of Pennsylvania at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 11 inclusion and 10 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 14 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in number of falls between the baseline visit and 1 year (time frame: 12 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT05375344, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 Oct 2026.