Pain, ChronicNCT05377645
The Effects of Cervical Mobilization on Cognitive Performance
A study testing Cyriax mobilization + traditional physiotherapy in people with Pain, Chronic, run by İSMAİL CEYLAN at 1 site in Turkey (Türkiye).
Trial summary
Non spesific cervical pain syndromes are the most common cervical pathologies encountered in clinical practice. Non spesific cervical pain syndrome occurs as a result of postural deformities. Read more about this study
- Who is it for?
- Ages 18 to 65 yearsHealthy volunteers can take part
- Conditions the study is for
- Pain, Chronic
- What is being tested?
- Cyriax mobilization + traditional physiotherapy
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 32 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Nov 2021to 1 May 2022
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Who had cervical pain longer than six weeks
- Getting at least five points from Neck Disability Index
Who cannot join
- Who had neck surgery,
- Who had traumatic spinal cord injury,
- Clinical diagnosis of radiculopathy,
- Clinical diagnosis of myelopathy (sensory or motor deficit),
- Clinical diagnosis of neurological or rheumatologic disease and structural scoliosis
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Kırşehir Ahi Evran Üniversitesi
Kırşehir, İç Anadolu, 40500
About this study
Official title: The Effects of Cervical Mobilization on Cognitive Performance and Anxiety in Individuals With Non-Specific Neck Pain
Non spesific cervical pain syndromes are the most common cervical pathologies encountered in clinical practice. Non spesific cervical pain syndrome occurs as a result of postural deformities.
Massage and mobilization techniques are used in the treatment of Non spesific cervical pain syndrome due to their analgesic effects. The Cyriax mobilization technique is a manual therapy method applies to correct the limitation of movement in the joint and to relieve pain and functional disorders. Many studies have shown that Cyriax mobilization technique provides faster and momentary painless joint movement compared to other physical therapy modalities. Cervical mobilisation techniques also have regulator effect on autonomic nerve system. Cervical mobilisation also has positive effects on anxiety and tension.
Read the detailed description
In this study, 32 patients with age range 18-65 who applied to Kırşehir Ahi Evran University Training and Research Hospital were examined. The individuals included in the study were divided into two groups according to the paired randomization method. These groups were control and intervention groups. Traditional physiotherapy methods were applied to the control group, traditional physiotherapy and Cyriax mobilisation techniques were applied to the intervention group. Traditional physiotherapy methods were included; Transcutaneous Electrical Nerve Stimulation (TENS), Ultrasound (US), isometric strengthening exercises.
For the evaluation of patients; Visual Analogue Scale (VAS), cervical goniometric measurements, Lowett muscle test, Burdon Test and Beck Anxiety Test were used.
- Conditions
- Pain, Chronic
- Being tested
- Cyriax mobilization + traditional physiotherapy
- Keywords
- Pain Mobilisation, Anxiety
- Medical subject headings
- Chronic Pain, Anxiety Disorders
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Cyriax mobilization + traditional physiotherapyOther
TENS, US, exercise
| Study group | Role | What they receive |
|---|---|---|
| Cervical mobilization | Experimental | Mobilization Cyriax's cervical mobilization technique and traditional physiotherapy were applied to the intervention group. For Cyriax Mobilization technique, the patient was asked to lying supine position. Cervical ROM applied all directions. Also AP and ML glides applied to the cervical region. The treatment was done 3 times a week for 2 weeks. Also traditional physiotherapy techniques were applied to the experimental group. Traditional physiotherapy techniques were applied to the intervention group. Conventional TENS type was used. Continuous ultrasound type was applied with full contact technique.. And; isometric cervical strengthening exercises applied. The treatment was done 3 times a week for 2 weeks. Receives: Other: Cyriax mobilization + traditional physiotherapy |
| Traditional physiotherapy | Active comparator | Traditional physiotherapy techniques were applied to the intervention group. Conventional TENS type was used. Current transition time was set as 50-100 µs. TENS application is performed at a frequency of 100 Hertz for 20 minutes in amplitude that does not cause muscle contraction in the patient and creates a feeling of numbness and tingling. Continuous ultrasound type was applied with full contact technique. Ultrasound treatment was applied over the suboccipital area with circular movements towards the proximal and distal at a speed of 1-2.5 cm per second, at a dose of 1 W / cm2, for 6 minutes, with a frequency of 3 MHz. And; isometric cervical strengthening exercises applied. The treatment was done 3 times a week for 2 weeks. Receives: Other: Cyriax mobilization + traditional physiotherapy |
What is being measured
The primary outcome is the main question the study is designed to answer.
Visual Analogue Scale (VAS)
A Visual Analogue Scale (VAS) is a measurement instrument that tries to measure a characteristic or attitude that is believed to range across a continuum of values and cannot easily be directly measured. It is often used in epidemiologic and clinical research to measure the intensity or frequency of various symptoms. When responding to a VAS item, respondents specify their level of agreement to a statement by indicating a position along a continuous line between two end-points.
Measured: 0-2 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 May 2022
- Study start1 Nov 2021
- Primary completion1 Mar 2022
- Study completion1 May 2022
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Pain, ChronicStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Randomized Controlled Trial
- Masking
- None (open label)
- Enrolment
- 32 participants (actual)
Sponsor and investigators
- Lead sponsor
- İSMAİL CEYLAN
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, İSMAİL CEYLAN, Ahi Evran University Education and Research Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05377645
- Sponsor's protocol ID
- 12068451747
- Status last verified
- May 2022
- First submitted
- 9 May 2022
- Last updated
- 17 May 2022
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Calixtre LB, Oliveira AB, de Sena Rosa LR, Armijo-Olivo S, Visscher CM, Alburquerque-Sendin F. Effectiveness of mobilisation of the upper cervical region and craniocervical flexor training on orofacial pain, mandibular function and headache in women with TMD. A randomised, controlled trial. J Oral Rehabil. 2019 Feb;46(2):109-119. doi: 10.1111/joor.12733. Epub 2018 Oct 26.
PubMed 30307636
Study at a glance
From the registry record, last updated by the sponsor on 17 May 2022. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effects of Cervical Mobilization on Cognitive Performance and Anxiety in Individuals With Non-Specific Neck Pain
- ClinicalTrials.gov ID
- NCT05377645
- Acronym / sponsor ID
- 12068451747
- Conditions
- Pain, Chronic
- Keywords
- Pain Mobilisation, Anxiety
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 32 participants (actual)
- Lead sponsor
- İSMAİL CEYLANUniversity, hospital or other
- Study start
- 1 Nov 2021 (actual)
- Primary completion
- 1 Mar 2022 (actual)
- Study completion
- 1 May 2022 (actual)
- First posted
- 17 May 2022 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Non spesific cervical pain syndromes are the most common cervical pathologies encountered in clinical practice. Non spesific cervical pain syndrome occurs as a result of postural deformities.
Massage and mobilization techniques are used in the treatment of Non spesific cervical pain syndrome due to their analgesic effects. The Cyriax mobilization technique is a manual therapy method applies to correct the limitation of movement in the joint and to relieve pain and functional disorders. Many studies have shown that Cyriax mobilization technique provides faster and momentary painless joint movement compared to other physical therapy modalities. Cervical mobilisation techniques also have regulator effect on autonomic nerve system. Cervical mobilisation also has positive effects on anxiety and tension.
Detailed description
In this study, 32 patients with age range 18-65 who applied to Kırşehir Ahi Evran University Training and Research Hospital were examined. The individuals included in the study were divided into two groups according to the paired randomization method. These groups were control and intervention groups. Traditional physiotherapy methods were applied to the control group, traditional physiotherapy and Cyriax mobilisation techniques were applied to the intervention group. Traditional physiotherapy methods were included; Transcutaneous Electrical Nerve Stimulation (TENS), Ultrasound (US), isometric strengthening exercises.
For the evaluation of patients; Visual Analogue Scale (VAS), cervical goniometric measurements, Lowett muscle test, Burdon Test and Beck Anxiety Test were used.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- Randomized Controlled Trial
| Arm | Type | Receives |
|---|---|---|
| Cervical mobilization | Experimental | Other: Cyriax mobilization + traditional physiotherapyMobilization Cyriax's cervical mobilization technique and traditional physiotherapy were applied to the intervention group. For Cyriax Mobilization technique, the patient was asked to lying supine position. Cervical ROM applied all directions. Also AP and ML glides applied to the cervical region. The treatment was done 3 times a week for 2 weeks. Also traditional physiotherapy techniques were applied to the experimental group. Traditional physiotherapy techniques were applied to the intervention group. Conventional TENS type was used. Continuous ultrasound type was applied with full contact technique.. And; isometric cervical strengthening exercises applied. The treatment was done 3 times a week for 2 weeks. |
| Traditional physiotherapy | Active comparator | Other: Cyriax mobilization + traditional physiotherapyTraditional physiotherapy techniques were applied to the intervention group. Conventional TENS type was used. Current transition time was set as 50-100 µs. TENS application is performed at a frequency of 100 Hertz for 20 minutes in amplitude that does not cause muscle contraction in the patient and creates a feeling of numbness and tingling. Continuous ultrasound type was applied with full contact technique. Ultrasound treatment was applied over the suboccipital area with circular movements towards the proximal and distal at a speed of 1-2.5 cm per second, at a dose of 1 W / cm2, for 6 minutes, with a frequency of 3 MHz. And; isometric cervical strengthening exercises applied. The treatment was done 3 times a week for 2 weeks. |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (2 listed)
- Who had cervical pain longer than six weeks
- Getting at least five points from Neck Disability Index
Key exclusion criteria (5 listed)
- Who had neck surgery,
- Who had traumatic spinal cord injury,
- Clinical diagnosis of radiculopathy,
- Clinical diagnosis of myelopathy (sensory or motor deficit),
- Clinical diagnosis of neurological or rheumatologic disease and structural scoliosis
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Cyriax mobilization + traditional physiotherapyTENS, US, exercise | Other | Cervical mobilization, Traditional physiotherapy |
Primary outcome
Visual Analogue Scale (VAS)
Time frame: 0-2 weeks
A Visual Analogue Scale (VAS) is a measurement instrument that tries to measure a characteristic or attitude that is believed to range across a continuum of values and cannot easily be directly measured. It is often used in epidemiologic and clinical research to measure the intensity or frequency of various symptoms. When responding to a VAS item, respondents specify their level of agreement to a statement by indicating a position along a continuous line between two end-points.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 May 2022.
- Background: PubMed 30307636Calixtre LB, Oliveira AB, de Sena Rosa LR, Armijo-Olivo S, Visscher CM, Alburquerque-Sendin F. Effectiveness of mobilisation of the upper cervical region and craniocervical flexor training on orofacial pain, mandibular function and headache in women with TMD. A randomised, controlled trial. J Oral Rehabil. 2019 Feb;46(2):109-119. doi: 10.1111/joor.12733. Epub 2018 Oct 26.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Cyriax mobilization + traditional physiotherapy in people with Pain, Chronic, run by İSMAİL CEYLAN at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 17 May 2022. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Visual Analogue Scale (VAS) (time frame: 0-2 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT05377645, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 May 2022; AzTrials last refreshed its copy on 6 Nov 2026.