Insertion of Peripherally Inserted Central CatheterNCT05399875
AR Ruler to Improve Safety and Clinical Workflow During PICC Placement
A study testing Augmented reality virtual ruler in people with Insertion of Peripherally Inserted Central Catheter, run by University of Pennsylvania at 1 site in United States.
Trial summary
The purpose of this study is to assess the utility of an augmented reality virtual ruler during placement of peripherally inserted central catheters. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Insertion of Peripherally Inserted Central Catheter
- What is being tested?
- Augmented reality virtual ruler
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 29 participants
- Where
- 1 siteUnited States
- Study dates
- 26 Sep 2022to 30 Jun 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Scheduled for a non-emergent peripherally inserted central catheter placement in Interventional Radiology
- Over 18 years
Who cannot join
- Undergoing an emergent peripherally inserted central catheter placement
- Younger than 18 years old
Trial locations and contacts
1 site in 1 country.
United States1 site
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania, 19104
About this study
Official title: Augmented Reality Ruler to Improve Safety and Clinical Workflow During Placement of Peripherally Inserted Central Catheters
The purpose of this study is to assess the utility of an augmented reality virtual ruler during placement of peripherally inserted central catheters.
Read the detailed description
After being informed about the study, patients who give consent will have their peripheral inserted central catheter placed by a physician wearing mixed reality smart glasses. The mixed reality smart glasses will have an application that allows the physician to measure distances with their hands. This application will be used to measure the appropriate length for which to trim the central catheter.
- Being tested
- Augmented reality virtual ruler
- Keywords
- Catheters, Augmented Reality, Radiology, Interventional
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Augmented reality virtual rulerOther
Use of augmented reality virtual ruler to measure catheter length
| Study group | Role | What they receive |
|---|---|---|
| Augmented reality virtual ruler | Experimental | Patient's in this arm will have their physician use an augmented reality virtual ruler to measure catheter length during catheter placement. Receives: Other: Augmented reality virtual ruler |
What is being measured
The primary outcome is the main question the study is designed to answer.
Number of participants with appropriate catheter tip location
Catheter tip location will be evaluated by the treating physician on x-ray
Measured: End of procedure
Secondary outcomes (2)
Radiation dose
Total radiation dose of the procedure will be captured from the fluoroscopy machine
Measured: End of procedure
Procedure time
Procedure time to complete catheter placement will be captured from the radiology information system.
Measured: End of procedure
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted1 Jun 2022
- Study start26 Sep 2022
- Primary completion24 Feb 2025
- Study completion30 Jun 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Insertion of Peripherally Inserted Central CatheterStudies of the same condition, open and under way.
- More trials run by University of PennsylvaniaThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 29 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Pennsylvania
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ali Dhanaliwala, University of Pennsylvania
- Investigators
- Ali H Dhanaliwala, MD, PhD, Principal investigator, University of Pennsylvania
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05399875
- Sponsor's protocol ID
- 851278
- Status last verified
- Oct 2026
- First submitted
- 26 May 2022
- Last updated
- 30 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data will not be shared.
Publications
Dhanaliwala AH, Nadolski G, Shlansky-Goldberg R, Depietro D, Hunt S, Park B, Gade T. Integrating Extended Reality into Interventional Radiology: A Single Center Feasibility Study of a Virtual Ruler for PICC Line Placement. J Vasc Interv Radiol. 2026 Sep 7:109064. doi: 10.1016/j.jvir.2026.109064. Online ahead of print.
PubMed 42705575
Study at a glance
From the registry record, last updated by the sponsor on 30 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Augmented Reality Ruler to Improve Safety and Clinical Workflow During Placement of Peripherally Inserted Central Catheters
- ClinicalTrials.gov ID
- NCT05399875
- Acronym / sponsor ID
- 851278
- Keywords
- Catheters, Augmented Reality, Radiology, Interventional
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 29 participants (actual)
- Lead sponsor
- University of PennsylvaniaUniversity, hospital or other
- Study start
- 26 Sep 2022 (actual)
- Primary completion
- 24 Feb 2025 (actual)
- Study completion
- 30 Jun 2026 (actual)
- First posted
- 1 Jun 2022 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study is to assess the utility of an augmented reality virtual ruler during placement of peripherally inserted central catheters.
Detailed description
After being informed about the study, patients who give consent will have their peripheral inserted central catheter placed by a physician wearing mixed reality smart glasses. The mixed reality smart glasses will have an application that allows the physician to measure distances with their hands. This application will be used to measure the appropriate length for which to trim the central catheter.
Study design
- Primary purpose
- Other
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Augmented reality virtual ruler | Experimental | Other: Augmented reality virtual rulerPatient's in this arm will have their physician use an augmented reality virtual ruler to measure catheter length during catheter placement. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (2 listed)
- Scheduled for a non-emergent peripherally inserted central catheter placement in Interventional Radiology
- Over 18 years
Key exclusion criteria (2 listed)
- Undergoing an emergent peripherally inserted central catheter placement
- Younger than 18 years old
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Augmented reality virtual rulerUse of augmented reality virtual ruler to measure catheter length | Other | Augmented reality virtual ruler |
Primary outcome
Number of participants with appropriate catheter tip location
Time frame: End of procedure
Catheter tip location will be evaluated by the treating physician on x-ray
2 secondary outcomes
Radiation dose
Time frame: End of procedure
Procedure time
Time frame: End of procedure
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 30 Oct 2026.
- Results publication: PubMed 42705575Dhanaliwala AH, Nadolski G, Shlansky-Goldberg R, Depietro D, Hunt S, Park B, Gade T. Integrating Extended Reality into Interventional Radiology: A Single Center Feasibility Study of a Virtual Ruler for PICC Line Placement. J Vasc Interv Radiol. 2026 Sep 7:109064. doi: 10.1016/j.jvir.2026.109064. Online ahead of print.
- Individual participant dataSharing planned: No. Individual participant data will not be shared.
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Ali H Dhanaliwala, MD, PhD principal investigator
University of Pennsylvania
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Augmented reality virtual ruler in people with Insertion of Peripherally Inserted Central Catheter, run by University of Pennsylvania at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 30 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Number of participants with appropriate catheter tip location (time frame: End of procedure). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT05399875, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 30 Oct 2026; AzTrials last refreshed its copy on 6 Nov 2026.