School PhobiaMulti-FastNCT05432323
Multi-family Therapy and School Refusal: an Exploratory Study With Adolescents and Their Families
An observational study of School Phobia, run by Assistance Publique - Hôpitaux de Paris at 1 site in France.
Trial summary
The purpose of this study is to determine whether multi-family therapy is effective in the treatment of school refusal with anxiety in adolescence. Read more about this study
- Who is it for?
- Ages 12 to 18 years
- Conditions the study is for
- School Phobia
- What is being tested?
- Multi-family therapy
- Type of treatment
- Lifestyle or therapy programme
- How many people
- 74 participants
- Where
- 1 siteFrance
- Study dates
- 12 Sep 2022to 13 Mar 2025
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 12 to 18 years
- All sexes
- No healthy volunteers
- Child, Adult
Study population: Cochin Hospital, Maison de Solenn-Maison des Adolescents, Paris, AP-HP Primary care clinic, Day care clinic
Who may be able to join
- Families with an adolescent
- Aged 12 to 18
- Totally out of school for more than 2 consecutive weeks and less than 18 months
- Follow-up at the Maison de Solenn-Maison des Adolescents (Cochin Hospital AP-HP) for a school refusal
- Having agreed to participate in a multi-family therapy
- Domiciliation in Ile de France
- Agreement of the parents and the adolescent to participate in the study: Collection of the non-opposition of non-emancipated minors and their legal representatives
Who cannot join
- any family situation that makes it impossible to bring parents and children together in family therapy
- patient under curatorship or tutorship
- patient with AME (french State Medical Aid)
Trial locations and contacts
1 site in 1 country.
France1 site
Maison de Solenn Maison des Adolescents, Cochin Hospital
Paris, IDF, 75014
About this study
The purpose of this study is to determine whether multi-family therapy is effective in the treatment of school refusal with anxiety in adolescence.
Read the detailed description
Anxious school refusal in adolescence is a major public health problem. The involvement of families is essential and multi-family therapy has shown its effectiveness for many mental disorders. This study aims to explore the benefit of multi-family therapy in the care of anxious school refusal in adolescence.
The method will be qualitative with phenomenological analysis of semi-structured interviews with adolescents and their parents and quantitative with a SCED design to assess the evolution of the level of anxiety of adolescents and parents, as well as personalized objectives.
The objective is therefore to improve the care of adolescents with anxious school refusal.
- Conditions
- School Phobia
- Being tested
- Multi-family therapy
- Keywords
- Adolescence, School Phobia, Multi-family therapy, Anxiety disorder
- Medical subject headings
- Phobia, School, Anxiety Disorders
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Multi-family therapyBehavioural
8 sessions of Multi-family therapy of 3 hours each during 24 weeks
| Study group | Role | What they receive |
|---|---|---|
| Adolescents | Not described Receives: Behavioral: Multi-family therapy | |
| Parents | Not described Receives: Behavioral: Multi-family therapy |
What is being measured
The primary outcome is the main question the study is designed to answer.
Visual Analogue Scale (VAS)
Visual Analogue Scale for anxiety (adolescents and parents) / 0 = no anxiety at all, 10 = maximum anxiety imaginable / Weekly measurement between inclusion and the end of the Single Case Experimental Design (SCED) follow-up (13 to 15 months)
Measured: 13 to 15 months
Secondary outcomes (7)
Goal Attainment Scale (GAS)
School attendance (adolescent) / 3-terminal GAS are 5-level GAS, i.e. with a possible rating ranging from -2 to +2. Level -2 corresponds to the initial state at the time of inclusion. Levels -2, 0 and +2 are precisely described, level -1 corresponds to a rating between -2 and 0 and level +1 to a rating between 0 and +2 / Weekly measurements, parents and adolescent, once a week from inclusion to the end of the SCED follow-up (13 to 15 months)
Measured: 13 to 15 months
Adolescent Depression Rating Scale (ADRS)
Depression (adolescent) / 10 questions / Monthly measurements, adolescent and referring psychiatrist once a month from inclusion to the end of the SCED follow-up (13 to 15 months)
Measured: 13 to 15 months
Family Assessment Device General Functioning (FAD-GF)
Family functioning / 12 questions, minimum = 12, maximum = 48 / Monthly measurements, parents and adolescent, once a month from inclusion to the end of the SCED follow-up (13 to 15 months)
Measured: 13 to 15 months
Global Assessment of Functioning Scale (GAF)
Global Functioning of the adolescent / From 0 = inadequate information, to 100 = higher level of functioning in a wide variety of activities - V-axis of the DSM 5 / Monthly measurements, referring psychiatrist, once a month from inclusion to the end of the SCED follow-up (13 to15 months)
Measured: 13 to 15 months
CSQ 8 (Client Satisfaction Questionnaire)
Satisfaction of the patients and the parents with multi-family therapy / 8 questions, minimum score = 8, maximum = 32 / At the end of the multifamily therapy, parents and teenager
Measured: 7 to 9 months
Semi-structured interview
Semi-structured interview with qualitative phenomenological analysis (patients and parents) At the end of multi-family therapy
Measured: 7 to 9 months
Semi-structured interview
Semi-structured interview with qualitative phenomenological analysis (patients and parents) 12 months after the end of multi-family therapy
Measured: 19 to 21 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted27 Jun 2022
- Study start12 Sep 2022
- Primary completion2 Mar 2024
- Study completion13 Mar 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for School PhobiaStudies of the same condition, open and under way.
- More trials run by Assistance Publique - Hôpitaux de ParisThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 74 participants (actual)
Sponsor and investigators
- Lead sponsor
- Assistance Publique - Hôpitaux de Paris
- Sponsor type
- University, hospital or other
- Collaborators
- URC-CIC Paris Descartes Necker Cochin
- Responsible party
- Sponsor
- Investigators
- Marie-Rose MORO, MD, PhD, PU-PH, Study director, Cochin Hospital, Assistance Publique des Hôpitaux de Paris (AP-HP)Aurélie HARF, MD, PhD, Principal investigator, Cochin Hospital, Assistance Publique des Hôpitaux de Paris (AP-HP)
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05432323
- Sponsor's protocol ID
- APHP211594
- Other IDs
- 2021-A01853-38
- Acronym
- Multi-Fast
- Status last verified
- May 2026
- First submitted
- 14 Jun 2022
- Last updated
- 20 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 20 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Multi-family Therapy and School Refusal: an Exploratory Study With Adolescents and Their Families
- ClinicalTrials.gov ID
- NCT05432323
- Acronym / sponsor ID
- Multi-Fast / APHP211594
- Conditions
- School Phobia
- Keywords
- Adolescence, School Phobia, Multi-family therapy, Anxiety disorder
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 74 participants (actual)
- Lead sponsor
- Assistance Publique - Hôpitaux de ParisUniversity, hospital or other
- Collaborators
- URC-CIC Paris Descartes Necker Cochin
- Study start
- 12 Sep 2022 (actual)
- Primary completion
- 2 Mar 2024 (actual)
- Study completion
- 13 Mar 2025 (actual)
- First posted
- 27 Jun 2022 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study is to determine whether multi-family therapy is effective in the treatment of school refusal with anxiety in adolescence.
Detailed description
Anxious school refusal in adolescence is a major public health problem. The involvement of families is essential and multi-family therapy has shown its effectiveness for many mental disorders. This study aims to explore the benefit of multi-family therapy in the care of anxious school refusal in adolescence.
The method will be qualitative with phenomenological analysis of semi-structured interviews with adolescents and their parents and quantitative with a SCED design to assess the evolution of the level of anxiety of adolescents and parents, as well as personalized objectives.
The objective is therefore to improve the care of adolescents with anxious school refusal.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Adolescents | – | Behavioral: Multi-family therapy |
| Parents | – | Behavioral: Multi-family therapy |
Who may qualify
- Ages
- 12 to 18 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult
- Study population
- Cochin Hospital, Maison de Solenn-Maison des Adolescents, Paris, AP-HP Primary care clinic, Day care clinic
Key inclusion criteria (7 listed)
- Families with an adolescent
- Aged 12 to 18
- Totally out of school for more than 2 consecutive weeks and less than 18 months
- Follow-up at the Maison de Solenn-Maison des Adolescents (Cochin Hospital AP-HP) for a school refusal
- Having agreed to participate in a multi-family therapy
Key exclusion criteria (3 listed)
- any family situation that makes it impossible to bring parents and children together in family therapy
- patient under curatorship or tutorship
- patient with AME (french State Medical Aid)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Multi-family therapy8 sessions of Multi-family therapy of 3 hours each during 24 weeks | Behavioural | Adolescents, Parents |
Primary outcome
Visual Analogue Scale (VAS)
Time frame: 13 to 15 months
Visual Analogue Scale for anxiety (adolescents and parents) / 0 = no anxiety at all, 10 = maximum anxiety imaginable / Weekly measurement between inclusion and the end of the Single Case Experimental Design (SCED) follow-up (13 to 15 months)
7 secondary outcomes
Goal Attainment Scale (GAS)
Time frame: 13 to 15 months
Adolescent Depression Rating Scale (ADRS)
Time frame: 13 to 15 months
Family Assessment Device General Functioning (FAD-GF)
Time frame: 13 to 15 months
Global Assessment of Functioning Scale (GAF)
Time frame: 13 to 15 months
CSQ 8 (Client Satisfaction Questionnaire)
Time frame: 7 to 9 months
Semi-structured interview
Time frame: 7 to 9 months
Semi-structured interview
Time frame: 19 to 21 months
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 20 May 2026.
- Individual participant dataSharing planned: No
Related trials for School Phobia
Not yet recruitingObservational study
Evaluation of the Effectiveness of Day Hospital Care for Adolescents With Anxious School Refusal
School Phobia
Recruiting
School-based Treatment of Social Anxiety With Developmentally Oriented Cognitive Therapy for Social Anxiety Disorder
Social Anxiety Disorder, Social Anxiety
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Marie-Rose MORO, MD, PhD, PU-PH study director
Cochin Hospital, Assistance Publique des Hôpitaux de Paris (AP-HP)
Aurélie HARF, MD, PhD principal investigator
Cochin Hospital, Assistance Publique des Hôpitaux de Paris (AP-HP)
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of School Phobia, run by Assistance Publique - Hôpitaux de Paris at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 20 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Visual Analogue Scale (VAS) (time frame: 13 to 15 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 20 May 2026.