Postoperative RecoveryTRANSATNCT05450172
Impact of Postoperative Transitional Pain on Recovery After Thoracic Surgery
An observational study of Postoperative Recovery, run by University Hospital, Angers at 1 site in France.
Trial summary
Postoperative transitional pain corresponds to the pain occuring between acute postoperative pain and chronic postsurgical pain (defined as pain persisting for at least 3 months after surgery). Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Postoperative Recovery
- What is being tested?
- QoR-15 questionnaire
- How many people
- 204 participants
- Where
- 1 siteFrance
- Study dates
- 10 Oct 2022to 10 Jun 2024
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Patients scheduled for thoracic surgery (thoracotomy or video-assisted thoracic surgery or surgery for thoracic outlet syndrome).
Who may be able to join
- adult patients
- patients scheduled for thoracic surgery (thoracotomy or video-assisted thoracic surgery or surgery for thoracic outlet syndrome)
- patients who do not object to the study
Who cannot join
- patients non francophone
- emergency surgery or revision surgery
- patients already included in the study during the previous 6 months
Trial locations and contacts
1 site in 1 country.
About this study
Postoperative transitional pain corresponds to the pain occuring between acute postoperative pain and chronic postsurgical pain (defined as pain persisting for at least 3 months after surgery). We hypothesized that both trajectory and neuropathic component of transitional pain may influence the quality of recovery after thoracic surgery. To test this, we designed an observational study to identify risk factors for incomplete recovery assessed through the QoR-15 questionnaire.
- Conditions
- Postoperative Recovery
- Being tested
- QoR-15 questionnaire
- Keywords
- Postoperative transitional pain, postoperative pain trajectory, postoperative neuropathic pain, thoracic surgery
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
QoR-15 questionnaireOther
Also called DN4 questionnaire
The QoR-15 is a 15-item questionnaire on postoperative quality of recovery. The DN4 is a 10-item questionnaire on neuropathic pain. Both questionnaires will be given to the patients preoperatively, on postoperative days 2 and 3, and 1, 3 and 6 months after surgery.
| Study group | Role | What they receive |
|---|---|---|
| Consecutive patients scheduled for thoracic surgery | Not described Receives: Other: QoR-15 questionnaire |
What is being measured
The primary outcome is the main question the study is designed to answer.
Impact of pain trajectory and neuropathic component of pain on quality of recovery.
An incomplete recovery will be defined as a postoperative QoR-15 score of at least 8 points lower than the preoperative QoR-15 value. The association between both trajectory and neuropathic component of postoperative transitional pain and incomplete recovery will be evaluated.
Measured: 3 months after surgery.
Secondary outcomes (5)
Description of trajectory and neuropathic component of postoperative transitional pain.
To describe the trajectory and neuropathic component of postoperative transitional pain according to QoR-15 and DN4 successive values.
Measured: Between postoperative day 2 and 3 months after surgery.
Impact of the type of surgery on quality of recovery.
To assess the impact of thoracotomy or video-assisted thoracic on quality of recovery.
Measured: 3 months after surgery.
Impact of pain trajectory, neuropathic component of pain and type of surgery on chronic postsurgical pain prevalence.
To assess the impact pain trajectory, neuropathic component of pain and type of surgery on chronic postsurgical pain prevalence.
Measured: 3 and 6 months after surgery.
Predictive accuracy of neuropathic pain trajectory on incomplete recovery and chronic postsurgical pain prevalence.
To assess the predictive accuracy of neuropathic pain trajectory on incomplete recovery and chronic postsurgical pain prevalence.
Measured: 3 and 6 months after surgery.
Correlation between neuropathic componente of chronic postsurgical pain and quality of recovery.
To assess the correlation between neuropathic componente of chronic postsurgical pain and quality of recovery.
Measured: 3 and 6 months after surgery.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted8 Jul 2022
- Study start10 Oct 2022
- Primary completion10 Mar 2024
- Study completion10 Jun 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Postoperative RecoveryStudies of the same condition, open and under way.
- More trials run by University Hospital, AngersThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 204 participants (actual)
Sponsor and investigators
- Lead sponsor
- University Hospital, Angers
- Sponsor type
- Other government
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05450172
- Sponsor's protocol ID
- 49RC22_0203
- Acronym
- TRANSAT
- Status last verified
- Dec 2025
- First submitted
- 5 Jul 2022
- Last updated
- 30 Dec 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 30 Dec 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Impact of Postoperative Transitional Pain on Recovery After Thoracic Surgery
- ClinicalTrials.gov ID
- NCT05450172
- Acronym / sponsor ID
- TRANSAT / 49RC22_0203
- Conditions
- Postoperative Recovery
- Keywords
- Postoperative transitional pain, postoperative pain trajectory, postoperative neuropathic pain, thoracic surgery
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 204 participants (actual)
- Lead sponsor
- University Hospital, AngersOther government
- Study start
- 10 Oct 2022 (actual)
- Primary completion
- 10 Mar 2024 (actual)
- Study completion
- 10 Jun 2024 (actual)
- First posted
- 8 Jul 2022 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Postoperative transitional pain corresponds to the pain occuring between acute postoperative pain and chronic postsurgical pain (defined as pain persisting for at least 3 months after surgery). We hypothesized that both trajectory and neuropathic component of transitional pain may influence the quality of recovery after thoracic surgery. To test this, we designed an observational study to identify risk factors for incomplete recovery assessed through the QoR-15 questionnaire.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Consecutive patients scheduled for thoracic surgery | – | Other: QoR-15 questionnaire |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Patients scheduled for thoracic surgery (thoracotomy or video-assisted thoracic surgery or surgery for thoracic outlet syndrome).
Key inclusion criteria (3 listed)
- adult patients
- patients scheduled for thoracic surgery (thoracotomy or video-assisted thoracic surgery or surgery for thoracic outlet syndrome)
- patients who do not object to the study
Key exclusion criteria (3 listed)
- patients non francophone
- emergency surgery or revision surgery
- patients already included in the study during the previous 6 months
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| QoR-15 questionnaireAlso: DN4 questionnaireThe QoR-15 is a 15-item questionnaire on postoperative quality of recovery. The DN4 is a 10-item questionnaire on neuropathic pain. Both questionnaires will be given to the patients preoperatively, on postoperative days 2 and 3, and 1, 3 and 6 months after surgery. | Other | Consecutive patients scheduled for thoracic surgery |
Primary outcome
Impact of pain trajectory and neuropathic component of pain on quality of recovery.
Time frame: 3 months after surgery.
An incomplete recovery will be defined as a postoperative QoR-15 score of at least 8 points lower than the preoperative QoR-15 value. The association between both trajectory and neuropathic component of postoperative transitional pain and incomplete recovery will be evaluated.
5 secondary outcomes
Description of trajectory and neuropathic component of postoperative transitional pain.
Time frame: Between postoperative day 2 and 3 months after surgery.
Impact of the type of surgery on quality of recovery.
Time frame: 3 months after surgery.
Impact of pain trajectory, neuropathic component of pain and type of surgery on chronic postsurgical pain prevalence.
Time frame: 3 and 6 months after surgery.
Predictive accuracy of neuropathic pain trajectory on incomplete recovery and chronic postsurgical pain prevalence.
Time frame: 3 and 6 months after surgery.
Correlation between neuropathic componente of chronic postsurgical pain and quality of recovery.
Time frame: 3 and 6 months after surgery.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 30 Dec 2025.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Postoperative Recovery, run by University Hospital, Angers at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 30 Dec 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Impact of pain trajectory and neuropathic component of pain on quality of recovery. (time frame: 3 months after surgery.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 30 Dec 2025.