Smell FunctionsNCT05499845
Effects of Different Anesthesia on Odor Memory
An observational study of Smell Functions and Odor Memory, run by Zonguldak Bulent Ecevit University at 1 site in Turkey (Türkiye).
Trial summary
This study aimed to research the effect of different general anesthesia administration on postoperative smell functions and memory. Read more about this study
- Who is it for?
- Ages 18 to 60 yearsHealthy volunteers can take part
- Conditions the study is for
- Smell Functions, Odor Memory
- What is being tested?
- butanol threshold test and smell identification tests
- How many people
- 97 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Jan 2013to 1 Jul 2013
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 60 years
- All sexes
- Healthy volunteers accepted
- Adult
Study population: 97
Who may be able to join
- American Society of Anesthesiologists (ASA) I-II risk groups
- operated under elective conditions with general anesthesia requiring intubation
- operation durations of 40-180 minutes.
Who cannot join
- intracranial,
- endocrine or nasal surgery,
- pregnant cases,
- those with history of respiratory tract diseases and psychiatric disease, with disorder of odor reception and perception,
- with smoking and chronic alcohol use,
- requiring a nasogastric probe
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Comparison of the Effects of TIVA and Inhalation Anesthesia Methods on Olfactory Functions and Olfactory Memory
This study aimed to research the effect of different general anesthesia administration on postoperative smell functions and memory.
- Conditions
- Smell Functions, Odor Memory
- Being tested
- butanol threshold test and smell identification tests
- Keywords
- General anesthesia management, propofol, sevoflurane, odor memory, smell functions
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
butanol threshold test and smell identification testsDiagnostic test
no additional intervention
| Study group | Role | What they receive |
|---|---|---|
| Group P (n=40) (Propofol), | Not described Receives: Diagnostic Test: butanol threshold test and smell identification tests | |
| Group PS (n=40) (Propofol-Sevoflurane), | Not described Receives: Diagnostic Test: butanol threshold test and smell identification tests | |
| Group S (n=40) (Sevoflurane). | Not described Receives: Diagnostic Test: butanol threshold test and smell identification tests |
What is being measured
The primary outcome is the main question the study is designed to answer.
Butanol Threshold Test
threshold detection and odor discrimination
Measured: during 24 hour after surgery
Odor Identification Test
odor discrimination
Measured: during 24 hour after surgery
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted12 Aug 2022
- Study start1 Jan 2013
- Primary completion30 Jun 2013
- Study completion1 Jul 2013
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Smell FunctionsStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Prospective
- Enrolment
- 97 participants (actual)
Sponsor and investigators
- Lead sponsor
- Zonguldak Bulent Ecevit University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Gamze Küçükosman, Zonguldak Bulent Ecevit University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05499845
- Sponsor's protocol ID
- 2013/02
- Status last verified
- Aug 2022
- First submitted
- 2 Jun 2022
- Last updated
- 12 Aug 2022
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 12 Aug 2022. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of the Effects of TIVA and Inhalation Anesthesia Methods on Olfactory Functions and Olfactory Memory
- ClinicalTrials.gov ID
- NCT05499845
- Acronym / sponsor ID
- 2013/02
- Conditions
- Smell Functions, Odor Memory
- Keywords
- General anesthesia management, propofol, sevoflurane, odor memory, smell functions
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 97 participants (actual)
- Lead sponsor
- Zonguldak Bulent Ecevit UniversityUniversity, hospital or other
- Study start
- 1 Jan 2013 (actual)
- Primary completion
- 30 Jun 2013 (actual)
- Study completion
- 1 Jul 2013 (actual)
- First posted
- 12 Aug 2022 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aimed to research the effect of different general anesthesia administration on postoperative smell functions and memory.
Study design
- Observational model
- Other
- Time perspective
- Prospective
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Group P (n=40) (Propofol), | – | Diagnostic Test: butanol threshold test and smell identification tests |
| Group PS (n=40) (Propofol-Sevoflurane), | – | Diagnostic Test: butanol threshold test and smell identification tests |
| Group S (n=40) (Sevoflurane). | – | Diagnostic Test: butanol threshold test and smell identification tests |
Who may qualify
- Ages
- 18 to 60 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
- Study population
- 97
Key inclusion criteria (3 listed)
- American Society of Anesthesiologists (ASA) I-II risk groups
- operated under elective conditions with general anesthesia requiring intubation
- operation durations of 40-180 minutes.
Key exclusion criteria (6 listed)
- intracranial,
- endocrine or nasal surgery,
- pregnant cases,
- those with history of respiratory tract diseases and psychiatric disease, with disorder of odor reception and perception,
- with smoking and chronic alcohol use,
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| butanol threshold test and smell identification testsno additional intervention | Diagnostic test | Group P (n=40) (Propofol),, Group PS (n=40) (Propofol-Sevoflurane),, Group S (n=40) (Sevoflurane). |
Primary outcome
Butanol Threshold Test
Time frame: during 24 hour after surgery
threshold detection and odor discrimination
Odor Identification Test
Time frame: during 24 hour after surgery
odor discrimination
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 12 Aug 2022.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Smell Functions and Odor Memory, run by Zonguldak Bulent Ecevit University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 12 Aug 2022. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Butanol Threshold Test (time frame: during 24 hour after surgery). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 12 Aug 2022.