Mental Health IssueNCT05523843
Pilot Study on the Clinical Utility of the Tulsa Life Chart
An observational study of Mental Health Issue and Mental Health Disorder, run by Laureate Institute for Brain Research, Inc. at 1 site in United States.
Trial summary
The proposed study aims to examine the usability, utility, and feasibility of the Tulsa Life Chart (TLC) in a sample of patients seeking mental health treatment and their healthcare providers. The TLC is an interactive, web-based application used to create a graphical interface for visualizing a patient's life history. Read more about this study
- Who is it for?
- Ages 15 to 65 yearsHealthy volunteers can take part
- Conditions the study is for
- Mental Health Issue, Mental Health Disorder, Assessment, Self
- What is being tested?
- Tulsa Life Chart (TLC)
- How many people
- 63 participants
- Where
- 1 siteUnited States
- Study dates
- 12 Sep 2022to 31 Jan 2024
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 15 to 65 years
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Study population: Indviduals seeking mental health treatment and their healthcare providers who have been invited to participate in the study.
Who may be able to join
- Treatment Seekers Inclusion Criteria:
- Actively seeking mental health treatment at Laureate Psychiatric Clinic and Hospital
- Provision of informed consent or if <18 assent and parental consent
- Age 15 to 65 years
- Necessary resources to engage in a technology-based intervention
- English proficiency
Show all 12Show fewer
- Willingness to grant access to medical records
- HCPs Inclusion Criteria:
- Employed at Laureate Psychiatric Clinic and Hospital in a patient care role
- Informed consent
- English proficiency
- Access to resources to engage in technology-based intervention
Who cannot join
- Treatment Seekers Exclusion Criteria:
- Active suicidal ideation with plan or intent
- No access to resources to participate in a technology-based intervention
- Completed more than 2 sessions of therapy with their current provider prior to enrollment in the study
- Not proficient in English
- HCPs Exclusion Criteria:
- No access to resources to participate in a technology-based intervention
- Not proficient in English
Trial locations and contacts
1 site in 1 country.
United States1 site
Laureate Institute for Brain Research
Tulsa, Oklahoma, 74008
About this study
Official title: Pilot Study on the Clinical Utility of the Tulsa Life Chart: A Graphical Representation of Patient Life History
The proposed study aims to examine the usability, utility, and feasibility of the Tulsa Life Chart (TLC) in a sample of patients seeking mental health treatment and their healthcare providers. The TLC is an interactive, web-based application used to create a graphical interface for visualizing a patient's life history.
Read the detailed description
Understanding the longitudinal course of mental health is critical for case conceptualization. One approach for capturing the complexity of an individual's illness course is to depict it graphically. The first attempt for this method was the National Institute of Mental Health Life Chart for Bipolar Disorder. Subsequent research indicated Life Charts are useful clinically and time- and cost-effective. Despite clinical utility and time and cost efficiency, this approach has not been widely adopted in the mental health field. Possible explanations are the prior focus on bipolar disorder, time required to collect information, and prior versions have not had automatic translation of the patient information into an image.
The Tulsa Life Chart (TLC) was developed by researchers at the Laureate Institute for Brain Research (LIBR). The TLC was developed to address weaknesses of previous life chart methods and help patients and healthcare professionals (HCPs) quickly identify patterns of mental health symptoms across diagnostic categories. To date only one formal exploration of the TLC has been conducted in a sample of individuals with mood, anxiety, eating disorders, and substance use disorders, which suggested that participants felt the TLC was helpful in understanding their mental health symptoms and was pleasant to complete. Unpublished focus groups with HCPs suggest HCPs believe the TLC could help to improve patient encounters by increasing understanding of patients and facilitating conversations. Based on these findings the goal of the proposed study is to examine clinical usability, utility, and feasibility in a pragmatic pilot trial.
The current trial will recruit individuals seeking treatment within the Laureate Psychiatric Clinic and Hospital and healthcare professionals involved with their care. Treatment-seeking patients who are invited to participate will be asked to complete the TLC soon after establishing care in a health system setting. Subsequently, the patient's HCP will review the chart during the intake process and complete several measures related to the chart and their experience (baseline assessment point). Patients and HCPs will engage in treatment as usual in between the TLC and assessment time points. Prior to or shortly following discharge/termination of treatment (approximately 4 to 12 weeks depending on the clinic), patients and HCPs will be asked to again complete questions to determine the TLC's usefulness during treatment. The overarching aim of the current study is to examine the usefulness of the Tulsa Life Chart for treatment-seeking individuals and healthcare professionals.
- Being tested
- Tulsa Life Chart (TLC)
- Keywords
- Assessment, Life Chart, Web-based application, Clinical intake assessment, Pragmatic Clinical Pilot
- Medical subject headings
- Mental Disorders
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Tulsa Life Chart (TLC)Other
The TLC is a self-administered, interactive assessment of patient history. Participants are asked to provide information from birth to their current age in developmental epochs (i.e., ages 0 to 5; 6 to 10; 11 to 14; 15 to 18; 19 to 25; 26 to 35; and so on in 10-year increments). Participants are first asked to rate their average mood during the epoch. They are then asked about locations lived, schools attended, people they were close to, hobbies, medical conditions, medications, hospitalizations, direct and indirect substance use exposure, mental health symptoms, mental health treatment, and important life events. The information is then displayed in an interactive, graphic of the individual's life that is reviewable by the patient and the healthcare providers enrolled in the study that the patient consents to having access.
| Study group | Role | What they receive |
|---|---|---|
| Treatment seeking individuals | Individuals seeking treatment in the Laureate Psychiatric Clinic and Hospital (LPCH). Receives: Other: Tulsa Life Chart (TLC) | |
| Healthcare professionals | Healthcare professionals (HCPS) include nurses, psychologists, therapists, medical doctors, dieticians, etc who work at LPCH and are engaged in direct patient care. |
What is being measured
The primary outcome is the main question the study is designed to answer.
mHealth App Usability Questionnaire (MAUQ) Total Usability Score (Patient)
Validated self-report survey in which participants indicate how usable the assessment tool was, with scores ranging from 18 to 126. Higher scores indicate greater usability.
Measured: Baseline assessment
mHealth App Usability Questionnaire (MAUQ) Total Usability Score (Healthcare Professional)
Validated self-report survey in which healthcare professional participants indicate how usable the assessment tool was, with scores ranging from 18 to 126. Higher scores indicate greater usability.
Measured: Baseline assessment
Secondary outcomes (8)
mHealth App Usability Questionnaire (MAUQ) - Ease of Use Subscale (Patient)
Subscale of a validated self-report survey in which patient participants report how easy the assessment tool was to use. Ease of use scores range from 5 to 35 with higher scores indicating greater ease of use.
Measured: Baseline assessment
mHealth App Usability Questionnaire (MAUQ) - Ease of Use Subscale (Healthcare Professional)
Subscale of a validated self-report survey in which healthcare professional participants report how easy the assessment tool was to use. Ease of use scores range from 5 to 35 with higher scores indicating greater ease of use.
Measured: Baseline assessment
mHealth App Usability Questionnaire (MAUQ) - Interface and Satisfaction Subscale (Patient)
Subscale of a validated self-report survey in which patients rate their satisfaction with the assessment tool and the interface of the tool. Interface and satisfaction scores range from 7 to 49 with higher scores indicating greater satisfaction.
Measured: Baseline assessment
mHealth App Usability Questionnaire (MAUQ) - Interface and Satisfaction Subscale (Healthcare Professional)
Subscale of a validated self-report survey in which healthcare professionals rate their satisfaction with the assessment tool and the interface of the tool. Interface and satisfaction scores range from 7 to 49 with higher scores indicating greater satisfaction.
Measured: Baseline assessment
mHealth App Usability Questionnaire (MAUQ) - Usefulness Subscale (Patient)
Subscale of a validated self-report survey in which patients rate the usefulness of the assessment tool. Usefulness scores range from 6 to 42 with higher scores indicating greater usefulness.
Measured: Baseline assessment
mHealth App Usability Questionnaire (MAUQ) - Usefulness Subscale (Healthcare Professional)
Subscale of a validated self-report survey in which healthcare professionals rate the usefulness of the assessment tool. Usefulness scores range from 6 to 42 with higher scores indicating greater usefulness.
Measured: Baseline assessment
Time spent to complete the Tulsa Life Chart (Patient)
Treatment seekers self-report of time to complete the TLC and embedded time count from the TLC application.
Measured: Baseline assessment
Time spent to reviewing the Tulsa Life Chart (Healthcare Professional)
Healthcare professionals' self-report of time spent reviewing the TLC and embedded time count from the TLC application.
Measured: Baseline assessment
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted31 Aug 2022
- Study start12 Sep 2022
- Primary completion31 Jan 2024
- Study completion31 Jan 2024
Why it stopped: Funding was no longer available to support the project.
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (5)Papers the sponsor has linked to this study.
- Other trials for Mental Health IssueStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 63 participants (actual)
Sponsor and investigators
- Lead sponsor
- Laureate Institute for Brain Research, Inc.
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Robin Aupperle, Laureate Institute for Brain Research, Inc.
- Investigators
- Robin Aupperle, PhD, Principal investigator, Laureate Institute for Brain Research
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05523843
- Sponsor's protocol ID
- 2022-004
- Status last verified
- Aug 2026
- First submitted
- 22 Aug 2022
- Last updated
- 27 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: The current study is enrolling participants from a specific treatment center and the data being collected and visualized as part fo the Tulsa Life Chart would be able to be used to potentially identify the individual participants. Thus, no data from this study will be shared through open access databases. If the visualization data from the TLC is shared for publication, data will be modified to for participant confidentiality and privacy. Data obtained from questionnaire measures may be shared upon request.
Publications
Aupperle RL, Paulus MP, Kuplicki R, Touthang J, Victor T, Yeh HW; Tulsa 1000 Investigators; Khalsa SS. Web-Based Graphic Representation of the Life Course of Mental Health: Cross-Sectional Study Across the Spectrum of Mood, Anxiety, Eating, and Substance Use Disorders. JMIR Ment Health. 2020 Jan 28;7(1):e16919. doi: 10.2196/16919.
PubMed 32012081Manderscheid RW, Ryff CD, Freeman EJ, McKnight-Eily LR, Dhingra S, Strine TW. Evolving definitions of mental illness and wellness. Prev Chronic Dis. 2010 Jan;7(1):A19. Epub 2009 Dec 15.
PubMed 20040234Post RM, Roy-Byrne PP, Uhde TW. Graphic representation of the life course of illness in patients with affective disorder. Am J Psychiatry. 1988 Jul;145(7):844-8. doi: 10.1176/ajp.145.7.844.
PubMed 3381929Born C, Amann BL, Grunze H, Post RM, Scharer L. Saving time and money: a validation of the self ratings on the prospective NIMH Life-Chart Method (NIMH-LCM). BMC Psychiatry. 2014 May 7;14:130. doi: 10.1186/1471-244X-14-130.
PubMed 24886463Denicoff KD, Ali SO, Sollinger AB, Smith-Jackson EE, Leverich GS, Post RM. Utility of the daily prospective National Institute of Mental Health Life-Chart Method (NIMH-LCM-p) ratings in clinical trials of bipolar disorder. Depress Anxiety. 2002;15(1):1-9. doi: 10.1002/da.1078.
PubMed 11816046
Study at a glance
From the registry record, last updated by the sponsor on 27 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Pilot Study on the Clinical Utility of the Tulsa Life Chart: A Graphical Representation of Patient Life History
- ClinicalTrials.gov ID
- NCT05523843
- Acronym / sponsor ID
- 2022-004
- Keywords
- Assessment, Life Chart, Web-based application, Clinical intake assessment, Pragmatic Clinical Pilot
- Study type
- Observational
- Recruitment status
- TerminatedReason stopped: Funding was no longer available to support the project.
- Enrolment
- 63 participants (actual)
- Lead sponsor
- Laureate Institute for Brain Research, Inc.University, hospital or other
- Study start
- 12 Sep 2022 (actual)
- Primary completion
- 31 Jan 2024 (actual)
- Study completion
- 31 Jan 2024 (actual)
- First posted
- 31 Aug 2022 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The proposed study aims to examine the usability, utility, and feasibility of the Tulsa Life Chart (TLC) in a sample of patients seeking mental health treatment and their healthcare providers. The TLC is an interactive, web-based application used to create a graphical interface for visualizing a patient's life history.
Detailed description
Understanding the longitudinal course of mental health is critical for case conceptualization. One approach for capturing the complexity of an individual's illness course is to depict it graphically. The first attempt for this method was the National Institute of Mental Health Life Chart for Bipolar Disorder. Subsequent research indicated Life Charts are useful clinically and time- and cost-effective. Despite clinical utility and time and cost efficiency, this approach has not been widely adopted in the mental health field. Possible explanations are the prior focus on bipolar disorder, time required to collect information, and prior versions have not had automatic translation of the patient information into an image.
The Tulsa Life Chart (TLC) was developed by researchers at the Laureate Institute for Brain Research (LIBR). The TLC was developed to address weaknesses of previous life chart methods and help patients and healthcare professionals (HCPs) quickly identify patterns of mental health symptoms across diagnostic categories. To date only one formal exploration of the TLC has been conducted in a sample of individuals with mood, anxiety, eating disorders, and substance use disorders, which suggested that participants felt the TLC was helpful in understanding their mental health symptoms and was pleasant to complete. Unpublished focus groups with HCPs suggest HCPs believe the TLC could help to improve patient encounters by increasing understanding of patients and facilitating conversations. Based on these findings the goal of the proposed study is to examine clinical usability, utility, and feasibility in a pragmatic pilot trial.
The current trial will recruit individuals seeking treatment within the Laureate Psychiatric Clinic and Hospital and healthcare professionals involved with their care. Treatment-seeking patients who are invited to participate will be asked to complete the TLC soon after establishing care in a health system setting. Subsequently, the patient's HCP will review the chart during the intake process and complete several measures related to the chart and their experience (baseline assessment point). Patients and HCPs will engage in treatment as usual in between the TLC and assessment time points. Prior to or shortly following discharge/termination of treatment (approximately 4 to 12 weeks depending on the clinic), patients and HCPs will be asked to again complete questions to determine the TLC's usefulness during treatment. The overarching aim of the current study is to examine the usefulness of the Tulsa Life Chart for treatment-seeking individuals and healthcare professionals.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Treatment seeking individuals | – | Other: Tulsa Life Chart (TLC)Individuals seeking treatment in the Laureate Psychiatric Clinic and Hospital (LPCH). |
| Healthcare professionals | – | –Healthcare professionals (HCPS) include nurses, psychologists, therapists, medical doctors, dieticians, etc who work at LPCH and are engaged in direct patient care. |
Who may qualify
- Ages
- 15 to 65 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
- Study population
- Indviduals seeking mental health treatment and their healthcare providers who have been invited to participate in the study.
Key inclusion criteria (12 listed)
- Actively seeking mental health treatment at Laureate Psychiatric Clinic and Hospital
- Provision of informed consent or if <18 assent and parental consent
- Age 15 to 65 years
- Necessary resources to engage in a technology-based intervention
- English proficiency
Key exclusion criteria (8 listed)
- Active suicidal ideation with plan or intent
- No access to resources to participate in a technology-based intervention
- Completed more than 2 sessions of therapy with their current provider prior to enrollment in the study
- Not proficient in English
- No access to resources to participate in a technology-based intervention
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Tulsa Life Chart (TLC)The TLC is a self-administered, interactive assessment of patient history. Participants are asked to provide information from birth to their current age in developmental epochs (i.e., ages 0 to 5; 6 to 10; 11 to 14; 15 to 18; 19 to 25; 26 to 35; and so on in 10-year increments). Participants are first asked to rate their average mood during the epoch. They are then asked about locations lived, schools attended, people they were close to, hobbies, medical conditions, medications, hospitalizations, direct and indirect substance use exposure, mental health symptoms, mental health treatment, and important life events. The information is then displayed in an interactive, graphic of the individual's life that is reviewable by the patient and the healthcare providers enrolled in the study that the patient consents to having access. | Other | Treatment seeking individuals |
Primary outcome
mHealth App Usability Questionnaire (MAUQ) Total Usability Score (Patient)
Time frame: Baseline assessment
Validated self-report survey in which participants indicate how usable the assessment tool was, with scores ranging from 18 to 126. Higher scores indicate greater usability.
mHealth App Usability Questionnaire (MAUQ) Total Usability Score (Healthcare Professional)
Time frame: Baseline assessment
Validated self-report survey in which healthcare professional participants indicate how usable the assessment tool was, with scores ranging from 18 to 126. Higher scores indicate greater usability.
8 secondary outcomes
mHealth App Usability Questionnaire (MAUQ) - Ease of Use Subscale (Patient)
Time frame: Baseline assessment
mHealth App Usability Questionnaire (MAUQ) - Ease of Use Subscale (Healthcare Professional)
Time frame: Baseline assessment
mHealth App Usability Questionnaire (MAUQ) - Interface and Satisfaction Subscale (Patient)
Time frame: Baseline assessment
mHealth App Usability Questionnaire (MAUQ) - Interface and Satisfaction Subscale (Healthcare Professional)
Time frame: Baseline assessment
mHealth App Usability Questionnaire (MAUQ) - Usefulness Subscale (Patient)
Time frame: Baseline assessment
mHealth App Usability Questionnaire (MAUQ) - Usefulness Subscale (Healthcare Professional)
Time frame: Baseline assessment
Time spent to complete the Tulsa Life Chart (Patient)
Time frame: Baseline assessment
Time spent to reviewing the Tulsa Life Chart (Healthcare Professional)
Time frame: Baseline assessment
Results and safety
The study was stopped early (reason given: Funding was no longer available to support the project.). Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 27 Aug 2026.
- Background: PubMed 32012081Aupperle RL, Paulus MP, Kuplicki R, Touthang J, Victor T, Yeh HW; Tulsa 1000 Investigators; Khalsa SS. Web-Based Graphic Representation of the Life Course of Mental Health: Cross-Sectional Study Across the Spectrum of Mood, Anxiety, Eating, and Substance Use Disorders. JMIR Ment Health. 2020 Jan 28;7(1):e16919. doi: 10.2196/16919.
- Background: PubMed 20040234Manderscheid RW, Ryff CD, Freeman EJ, McKnight-Eily LR, Dhingra S, Strine TW. Evolving definitions of mental illness and wellness. Prev Chronic Dis. 2010 Jan;7(1):A19. Epub 2009 Dec 15.
- Background: PubMed 3381929Post RM, Roy-Byrne PP, Uhde TW. Graphic representation of the life course of illness in patients with affective disorder. Am J Psychiatry. 1988 Jul;145(7):844-8. doi: 10.1176/ajp.145.7.844.
- Background: PubMed 24886463Born C, Amann BL, Grunze H, Post RM, Scharer L. Saving time and money: a validation of the self ratings on the prospective NIMH Life-Chart Method (NIMH-LCM). BMC Psychiatry. 2014 May 7;14:130. doi: 10.1186/1471-244X-14-130.
- Background: PubMed 11816046Denicoff KD, Ali SO, Sollinger AB, Smith-Jackson EE, Leverich GS, Post RM. Utility of the daily prospective National Institute of Mental Health Life-Chart Method (NIMH-LCM-p) ratings in clinical trials of bipolar disorder. Depress Anxiety. 2002;15(1):1-9. doi: 10.1002/da.1078.
- Individual participant dataSharing planned: No. The current study is enrolling participants from a specific treatment center and the data being collected and visualized as part fo the Tulsa Life Chart would be able to be used to potentially identify the individual participants. Thus, no data from this study will be shared through open access databases. If the visualization data from the TLC is shared for publication, data will be modified to for participant confidentiality and privacy. Data obtained from questionnaire measures may be shared upon request.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Robin Aupperle, PhD principal investigator
Laureate Institute for Brain Research
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Mental Health Issue and Mental Health Disorder, run by Laureate Institute for Brain Research, Inc. at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 12 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: stopped early, as of the sponsor's last update on 27 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study was stopped early (reason given: Funding was no longer available to support the project.). Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
mHealth App Usability Questionnaire (MAUQ) Total Usability Score (Patient) (time frame: Baseline assessment). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT05523843, which also lists 5 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 27 Aug 2026.