OverweightNCT05530629
Effect of Resistance Training on Energy Intake and Appetite Regulation, 12-weeks Resistance Training
A study testing resistance training and Normal P.E. course in people with Overweight and Obese, run by Universiti Putra Malaysia at 1 site in China.
Trial summary
Resistance training is a common way of daily exercise which has a remarkable function in healthcare. It has been used in many diseases as a complementary method. Overweight and obesity are the sixth highest risk of death worldwide. Read more about this study
- Who is it for?
- Ages 18 to 22 years, women onlyHealthy volunteers can take part
- Conditions the study is for
- Overweight, Obese
- What is being tested?
- resistance training and Normal P.E. course
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 72 participants
- Where
- 1 siteChina
- Study dates
- 20 Aug 2022to 1 Dec 2023
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 22 years
- Women only
- Healthy volunteers accepted
- Adult
Who may be able to join
- Overweight or obese (BMI> 25)
- Female
- College students
- Healthy
Who cannot join
- The subjects lack regular and active exercise program in last three months
- The subjects are not on a diet in last three months. c, Do not have regular menstrual cycle or approaching the normal menstrual cycle
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effect of Different Intensity Resistance Training on Energy Intake and Appetite Regulation Among Overweight and Obese College Girl
Resistance training is a common way of daily exercise which has a remarkable function in healthcare. It has been used in many diseases as a complementary method. Overweight and obesity are the sixth highest risk of death worldwide. In recent years, the data show that the rate of overweight obese among college students shows a significant increasing trend. The common characteristics of overweight and obese people are strong appetite which is difficult to be controled and sedentary. resistance training is a solid supplement to physical education and how to reduce appetite of overweight and obese college female students through resistance training is the key to increase their health by university sport course. The training plan divides the training intensity into three levels including 45-50% one repetition maximum(1RM), 60-65% 1RM, 45-50% 1RM, respectively plus control group. Therefore, this experimental research examines the effectiveness and the differences of three Intensities resistance training on energy intake and appetite regulation among overweight and obese college girl. Finally, to evaluate whether the resistance training can reduce the overweight and obese female college students' energy intake and appetite regulation
Read the detailed description
On the basis of consulting relevant literature, this paper designs a 12 week teaching plan of resistance training through experimental design and quantitative research methods, combined with the characteristics of resistance training and the physiological characteristics of obese or overweight people. The purpose of this experiment is to provide a theoretical basis for improving the teaching methods of College Students' physical education, so as to improve the energy intake and appetite regulation of obese and overweight female college students, and then reduce their weight. And compared with ordinary daily physical education courses. Among them, the experimental group was divided into three groups, and the resistance training with intensity of 45-50% 1RM, 60-65% 1RM and 80-85% 1RM was carried out respectively. The control group carried out daily physical education teaching content. The number of participating samples in each group is 18 overweight or obese female college students, and the samples in each group are located in different campuses.
The first section of the training program of the experimental groups are warm up (10 mins) which including two parts. The first part is jogging and running indoor or stationary cycling outdoor with low intensity (5 minutes), the second part is muscle stretching: the Chinese eight set of radio kinetics (each movement 8 times) including stretch exercise, check augmentation exercise, kicking exercise, body side exercise, body rotation exercise, whole body exercise, jump exercise, cooling down exercise Then, the main resistance training section of the experimental group includes test press, late pull down, shoulder press, square, leg extension, leg curl, bicep curl, triceps extension, dominant crunches, lower back exercises In the last cool down phase, repeat the same content of muscle stretching as in the first part again.
Three times a week, with an interval of more than 48 hours. Each exercise of main resistance training takes 2 sets, and the repetition times of low intensity, medium intensity and high intensity are 16-18 times, 10-12 times and 6-8 times respectively. The rest time between low-intensity, medium-intensity and high-intensity groups is 1 minute, 1-2 minutes and 2-3 minutes respectively. The total duration of each training is about 1 hour, including warm up for about 10 minutes, main training time for about 45 minutes, and final cool down for about 5 minutes. In addition, the maximum strength was retested once at week 1, 5 and 9 respectively The control group only changed the resistance training part to normal P.E. course which carried out general teaching content according to the college syllabus, other settings are the same.
- Conditions
- Overweight, Obese
- Being tested
- resistance training, Normal P.E. course
- Keywords
- Resistance training, Energy intake, Appetite, College Girl
- Medical subject headings
- Overweight, Obesity
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
resistance trainingDevice
resistance training lasts for 12 weeks, three times a week, one hour each time, and the program of resistance training in the experimental group was divided into 10 exercises: Chest press, Lat pull down, Shoulder press, Squat, Leg extension, Leg curl, Bicep curl, Triceps extension, abdominal crunches, lower back exercises.
Normal P.E. courseDevice
Carry out general teaching content according to the college syllabus lasts for 12 weeks , three times a week, one hour each time, and the program of Normal P.E. course in the control group will be Physical recovery exercises, learn and practice queue formation, calisthenics, five step fists, long fist and Basic movements of Gymnastics gradually changed by week.
| Study group | Role | What they receive |
|---|---|---|
| High intensity of resistance training | Experimental | The intensity of 75-80% 1RM is used for high intensity resistance training group. The number of repetitions of each set is relatively few, only 6-8 times. The rest time between sets is relatively long, 2-3 minutes, so that the participants can better adapt to this intensity.
chest press, lat pull down, shoulder press and square, which are all trained through the multi-functional Smith machine.
Bicep curl and triceps extension are operated by purchasing dumbbells with different weights.
Leg extension and Leg curl use leg extension and curl machine Abdominal crunches and lower back exercises just do it by body weight training in yoga mat with abdominal curl and Lower back bridge Receives: Device: resistance training |
| Moderate intensity of resistance training | Experimental | The intensity of 60-65% 1RM is used for moderate intensity resistance training group. The repetition times of each set are relatively moderate, 10-12 times. The rest time between sets is relatively moderate, 1-2 minutes. The relative exercise volume of this group was consistent with that of other experimental groups chest press, lat pull down, shoulder press and square, which are all trained through the multi-functional Smith machine.
Bicep curl and triceps extension are operated by purchasing dumbbells with different weights.
Leg extension and Leg curl use leg extension and curl machine Abdominal crunches and lower back exercises just do it by body weight training in yoga mat with abdominal curl and Lower back bridge Receives: Device: resistance training |
| Low intensity of resistance training | Experimental | The intensity of 40-45% 1RM is used for low intensity resistance training group. The repetition times of each set are relatively more, 16-18 times. The rest time between groups is short, only about 1 minute, so that the participants can still maintain sufficient total exercise load under low intensity.
chest press, lat pull down, shoulder press and square, which are all trained through the multi-functional Smith machine.
Bicep curl and triceps extension are operated by purchasing dumbbells with different weights.
Leg extension and Leg curl use leg extension and curl machine Abdominal crunches and lower back exercises just do it by body weight training in yoga mat with abdominal curl and Lower back bridge Receives: Device: resistance training |
| Normal P.E. course | Other | Carry out general teaching content according to the college syllabus. Receives: Device: Normal P.E. course |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change from baseline BMI at 6 weeks and 12 weeks.
This parameter belongs to Obesity Degree.
Measured: Pretest: Before experiment; Mid-test: 6 weeks end; Post-test: 12 weeks end.
Change from baseline body fat percentage at 6 weeks and 12 weeks.
This parameter belongs to Obesity Degree.
Measured: Pretest: Before experiment; Mid-test: 6 weeks end; Post-test: 12 weeks end.
Change from baseline waist circumference at 6 weeks and 12 weeks.
This parameter belongs to Obesity Degree.
Measured: Pretest: Before experiment; Mid-test: 6 weeks end; Post-test: 12 weeks end.
Change from baseline energy intake at 6 weeks and 12 weeks.
This parameter will be recorded by Quantitative Daily Dietary Intake (QDI): three multiple-pass 24-hr recalls collected at each assessment time point by a research dietitian/technician. Analysis by Food Processor Nutrition Analysis Software (Version 9.6, 2005, ESHA Research, Salem, OR): recalls are analysed for calorie and macronutrient content
Measured: Pretest: Before experiment; Mid-test: 6 weeks end; Post-test: 12 weeks end.
Change from baseline hunger at 6 weeks and 12 weeks.
This parameter will be test by 100-mm visual analogue scale (VAS): test at 6:00-8:00 am following a 10h overnight fast, rate perceive appetite firstly. Then provide with a standardised caloric stimulus, at 30, 60, 90 and 120min post consumption rate perceived appetite again (r = 0.42 - 0.85).
At every time point, both lengths of VAS 100 mm were used to record desire to eat, hunger, fullness, and prospective food consumption. The four standardized questions were:
(i) how strong is your desire to eat? ("very weak" to "very strong"), (ii) how hungry do you feel? ("not hungry at all" to "as hungry as I've ever felt"), (iii) how full do you feel? ("not full at all" to "very full"), and (iv) how much food do you think you can eat? (Prospective food consumption; "nothing at all" to "a large amount") .
Measured: Pretest: Before experiment; Mid-test: 6 weeks end; Post-test: 12 weeks end.
Change from baseline fullness at 6 weeks and 12 weeks.
This parameter will be test by 100-mm visual analogue scale (VAS): test at 6:00-8:00 am following a 10h overnight fast, rate perceive appetite firstly. Then provide with a standardised caloric stimulus, at 30, 60, 90 and 120min post consumption rate perceived appetite again (r = 0.42 - 0.85).
At every time point, both lengths of VAS 100 mm were used to record desire to eat, hunger, fullness, and prospective food consumption. The four standardized questions were:
(i) how strong is your desire to eat? ("very weak" to "very strong"), (ii) how hungry do you feel? ("not hungry at all" to "as hungry as I've ever felt"), (iii) how full do you feel? ("not full at all" to "very full"), and (iv) how much food do you think you can eat? (Prospective food consumption; "nothing at all" to "a large amount") .
Measured: Pretest: Before experiment; Mid-test: 6 weeks end; Post-test: 12 weeks end.
Change from baseline desire to eat at 6 weeks and 12 weeks.
This parameter will be test by 100-mm visual analogue scale (VAS): test at 6:00-8:00 am following a 10h overnight fast, rate perceive appetite firstly. Then provide with a standardised caloric stimulus, at 30, 60, 90 and 120min post consumption rate perceived appetite again (r = 0.42 - 0.85).
At every time point, both lengths of VAS 100 mm were used to record desire to eat, hunger, fullness, and prospective food consumption. The four standardized questions were:
(i) how strong is your desire to eat? ("very weak" to "very strong"), (ii) how hungry do you feel? ("not hungry at all" to "as hungry as I've ever felt"), (iii) how full do you feel? ("not full at all" to "very full"), and (iv) how much food do you think you can eat? (Prospective food consumption; "nothing at all" to "a large amount") .
Measured: Pretest: Before experiment; Mid-test: 6 weeks end; Post-test: 12 weeks end.
Change from baseline prospective food consumption at 6 weeks and 12 weeks.
This parameter will be test by 100-mm visual analogue scale (VAS): test at 6:00-8:00 am following a 10h overnight fast, rate perceive appetite firstly. Then provide with a standardised caloric stimulus, at 30, 60, 90 and 120min post consumption rate perceived appetite again (r = 0.42 - 0.85).
At every time point, both lengths of VAS 100 mm were used to record desire to eat, hunger, fullness, and prospective food consumption. The four standardized questions were:
(i) how strong is your desire to eat? ("very weak" to "very strong"), (ii) how hungry do you feel? ("not hungry at all" to "as hungry as I've ever felt"), (iii) how full do you feel? ("not full at all" to "very full"), and (iv) how much food do you think you can eat? (Prospective food consumption; "nothing at all" to "a large amount") .
Measured: Pretest: Before experiment; Mid-test: 6 weeks end; Post-test: 12 weeks end.
Change from baseline glucose at 6 weeks and 12 weeks.
Blood is collected into Vacutainers (BectonDickinson, Franklin Lakes, NJ) containing SST Gel (Becton Dickinson), Ethylenediaminetetraacetic acid(EDTA), or heparin and is immediately placed on ice and centrifuged (4 C, 1500g, 15 min). The serum or plasma obtained is stored in multiple aliquots at 75 C until assayed (in duplicate).
Glucose is determined by the glucose oxidase method (Sigma-Aldrich Corp; 3.8% and 4.9% inter- and intraassay coefficients of variation) (70～140mg/dl or 3.9～7.8mmol/l)
Measured: Pretest: Before experiment; Mid-test: 6 weeks end; Post-test: 12 weeks end.
Change from baseline leptin at 6 weeks and 12 weeks.
Blood is collected into Vacutainers (BectonDickinson, Franklin Lakes, NJ) containing Serum-separating tube(SST) Gel (Becton Dickinson), EDTA, or heparin and is immediately placed on ice and centrifuged (4 C, 1500g, 15 min). The serum or plasma obtained is stored in multiple aliquots at 75 C until assayed (in duplicate).
Serum leptin is determined by an ELISA with a commercially available kit (EIA-2395, DRG, Marburg, Germany; 5.9% intraassay precision; 6.8% interassay accuracy; sensitivity of 0.5ng/ml).
Measured: Pretest: Before experiment; Mid-test: 6 weeks end; Post-test: 12 weeks end.
Change from baseline adiponectin at 6 weeks and 12 weeks.
Blood is collected into Vacutainers (BectonDickinson, Franklin Lakes, NJ) containing SST Gel (Becton Dickinson), EDTA, or heparin and is immediately placed on ice and centrifuged (4 C, 1500g, 15 min). The serum or plasma obtained is stored in multiple aliquots at 75 C until assayed (in duplicate).
Plasma adiponectin is analysed with a commercially available radioimmunoassay (RIA) (Linco Research, Inc., St. Charles, mo; 6.9% intraassay precision; 7.8% interassay accuracy; sensitivity of 0.5ng/ml.) (3~30μg/mL).
Measured: Pretest: Before experiment; Mid-test: 6 weeks end; Post-test: 12 weeks end.
Change from baseline NPY at 6 weeks and 12 weeks.
Blood is collected into Vacutainers (BectonDickinson, Franklin Lakes, NJ) containing SST Gel (Becton Dickinson), EDTA, or heparin and is immediately placed on ice and centrifuged (4 C, 1500g, 15 min). The serum or plasma obtained is stored in multiple aliquots at 75 C until assayed (in duplicate).
Neuropeptide Y is measured by Liquid Chromatography with tandem mass spectrometry (LC-MS/MS) (NPY; Phoenix Europe Gesellschaft mit beschränkter Haftung (GmbH), Karlsruhe, Germany; Sensitivity of 0.13 ng/ml; Intra-assay variability <5%) (51.23～209.65 pg/ml).
Measured: Pretest: Before experiment; Mid-test: 6 weeks end; Post-test: 12 weeks end.
Change from baseline Insulin at 6 weeks and 12 weeks.
Blood is collected into Vacutainers (BectonDickinson, Franklin Lakes, NJ) containing SST Gel (Becton Dickinson), EDTA, or heparin and is immediately placed on ice and centrifuged (4 C, 1500g, 15 min). The serum or plasma obtained is stored in multiple aliquots at 75 C until assayed (in duplicate).
Insulin is measured with an immunoassay (Access Immunoassay System, Beckman Coulter, Fullerton, California (CA); 4.9% intraassay precision; 3.8% interassay accuracy; sensitivity of 0.5 μu/ml) (60-100mg/dl).
Measured: Pretest: Before experiment; Mid-test: 6 weeks end; Post-test: 12 weeks end.
Change from baseline meal-time at 6 weeks and 12 weeks.
This parameter record by Quantitative Daily Dietary Intake (QDI): three multiple-pass 24-hr recalls collected at each assessment time point by a research dietitian/technician. Analysis by Food Processor Nutrition Analysis Software (Version 9.6, 2005, ESHA Research, Salem, OR): recalls are analysed for the percentage of day and night total kcals intake separately.
Measured: Pretest: Before experiment; Mid-test: 6 weeks end; Post-test: 12 weeks end.
Change from baseline stress of eating at 6 weeks and 12 weeks.
This parameter measured by The Salzburg Stress Eating Scale (SSES) which is the first to specifically address the relationship of stress experiences and coping failure on the one hand and increases or decreases in food intake on the other hand. Higher SSES scores indicate eating more when stressed, while lower scores indicate eating less when stressed.
Measured: Pretest: Before experiment; Mid-test: 6 weeks end; Post-test: 12 weeks end.
Change from baseline physical activity level at 6 weeks and 12 weeks.
This parameter measured by Global Physical Activity Questionnaire (GPAQ). The GPAQ covers several components of physical activity, such as intensity, duration, and frequency, and it assesses three domains in which physical activity is performed (occupational physical activity, transport-related physical activity, and physical activity during discretionary or leisure time) comprising 16 questions (P1-P16). Since it was developed by World Health Organization (WHO) in 2002, the GPAQ has undergone a research program which shows that it is valid and reliable. It has become the most common tool in diagnostic and evaluation studies of physical activity globally.
Measured: Pretest: Before experiment; Mid-test: 6 weeks end; Post-test: 12 weeks end.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted7 Sep 2022
- Study start20 Aug 2022
- Primary completion15 Oct 2022 (estimated)
- Study completion1 Dec 2023 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for OverweightStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- In this experiment, the three experimental groups will conduct different intensities resistance training, and the control group take the normal P.E. course.
- Masking
- Triple blind
- Who is masked
- Participant, Investigator, Outcomes assessor
- Enrolment
- 72 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Universiti Putra Malaysia
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Wang Qiang, Universiti Putra Malaysia
- Investigators
- Qiang Wang, Doctor, Principal investigator, Universiti Putra Malaysia
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05530629
- Sponsor's protocol ID
- Wang Qiang
- Status last verified
- Sep 2022
- First submitted
- 28 Aug 2022
- Last updated
- 7 Sep 2022
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Because this is my doctoral thesis and it has certain confidentiality, I won't share it until I finish my doctoral thesis
Publications
Bales CW, Hawk VH, Granville EO, Rose SB, Shields T, Bateman L, Willis L, Piner LW, Slentz CA, Houmard JA, Gallup D, Samsa GP, Kraus WE. Aerobic and resistance training effects on energy intake: the STRRIDE-AT/RT study. Med Sci Sports Exerc. 2012 Oct;44(10):2033-9. doi: 10.1249/MSS.0b013e318259479a.
PubMed 22525775Wang Q, Xiao WS, Danaee M, Geok SK, Gan WY, Zhu WL, Mai YQ. Impact of resistance training intensity on body composition and nutritional intake among college women with overweight and obesity: a cluster randomized controlled trial. Front Public Health. 2025 May 30;13:1589036. doi: 10.3389/fpubh.2025.1589036. eCollection 2025.
PubMed 40520279
Study at a glance
From the registry record, last updated by the sponsor on 7 Sep 2022. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Different Intensity Resistance Training on Energy Intake and Appetite Regulation Among Overweight and Obese College Girl
- ClinicalTrials.gov ID
- NCT05530629
- Acronym / sponsor ID
- Wang Qiang
- Conditions
- Overweight, Obese
- Keywords
- Resistance training, Energy intake, Appetite, College Girl
- Study type
- Interventional
- Recruitment status
- Unknown status
- Enrolment
- 72 participants (estimated)
- Lead sponsor
- Universiti Putra MalaysiaUniversity, hospital or other
- Study start
- 20 Aug 2022 (actual)
- Primary completion
- 15 Oct 2022 (estimated)
- Study completion
- 1 Dec 2023 (estimated)
- First posted
- 7 Sep 2022 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Resistance training is a common way of daily exercise which has a remarkable function in healthcare. It has been used in many diseases as a complementary method. Overweight and obesity are the sixth highest risk of death worldwide. In recent years, the data show that the rate of overweight obese among college students shows a significant increasing trend. The common characteristics of overweight and obese people are strong appetite which is difficult to be controled and sedentary. resistance training is a solid supplement to physical education and how to reduce appetite of overweight and obese college female students through resistance training is the key to increase their health by university sport course. The training plan divides the training intensity into three levels including 45-50% one repetition maximum(1RM), 60-65% 1RM, 45-50% 1RM, respectively plus control group. Therefore, this experimental research examines the effectiveness and the differences of three Intensities resistance training on energy intake and appetite regulation among overweight and obese college girl. Finally, to evaluate whether the resistance training can reduce the overweight and obese female college students' energy intake and appetite regulation
Detailed description
On the basis of consulting relevant literature, this paper designs a 12 week teaching plan of resistance training through experimental design and quantitative research methods, combined with the characteristics of resistance training and the physiological characteristics of obese or overweight people. The purpose of this experiment is to provide a theoretical basis for improving the teaching methods of College Students' physical education, so as to improve the energy intake and appetite regulation of obese and overweight female college students, and then reduce their weight. And compared with ordinary daily physical education courses. Among them, the experimental group was divided into three groups, and the resistance training with intensity of 45-50% 1RM, 60-65% 1RM and 80-85% 1RM was carried out respectively. The control group carried out daily physical education teaching content. The number of participating samples in each group is 18 overweight or obese female college students, and the samples in each group are located in different campuses.
The first section of the training program of the experimental groups are warm up (10 mins) which including two parts. The first part is jogging and running indoor or stationary cycling outdoor with low intensity (5 minutes), the second part is muscle stretching: the Chinese eight set of radio kinetics (each movement 8 times) including stretch exercise, check augmentation exercise, kicking exercise, body side exercise, body rotation exercise, whole body exercise, jump exercise, cooling down exercise Then, the main resistance training section of the experimental group includes test press, late pull down, shoulder press, square, leg extension, leg curl, bicep curl, triceps extension, dominant crunches, lower back exercises In the last cool down phase, repeat the same content of muscle stretching as in the first part again.
Three times a week, with an interval of more than 48 hours. Each exercise of main resistance training takes 2 sets, and the repetition times of low intensity, medium intensity and high intensity are 16-18 times, 10-12 times and 6-8 times respectively. The rest time between low-intensity, medium-intensity and high-intensity groups is 1 minute, 1-2 minutes and 2-3 minutes respectively. The total duration of each training is about 1 hour, including warm up for about 10 minutes, main training time for about 45 minutes, and final cool down for about 5 minutes. In addition, the maximum strength was retested once at week 1, 5 and 9 respectively The control group only changed the resistance training part to normal P.E. course which carried out general teaching content according to the college syllabus, other settings are the same.
Study design
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind (participant, investigator, outcomes assessor)
- Number of arms
- 4
- Model description
- In this experiment, the three experimental groups will conduct different intensities resistance training, and the control group take the normal P.E. course.
| Arm | Type | Receives |
|---|---|---|
| High intensity of resistance training | Experimental | Device: resistance trainingThe intensity of 75-80% 1RM is used for high intensity resistance training group. The number of repetitions of each set is relatively few, only 6-8 times. The rest time between sets is relatively long, 2-3 minutes, so that the participants can better adapt to this intensity. chest press, lat pull down, shoulder press and square, which are all trained through the multi-functional Smith machine. Bicep curl and triceps extension are operated by purchasing dumbbells with different weights. Leg extension and Leg curl use leg extension and curl machine Abdominal crunches and lower back exercises just do it by body weight training in yoga mat with abdominal curl and Lower back bridge |
| Moderate intensity of resistance training | Experimental | Device: resistance trainingThe intensity of 60-65% 1RM is used for moderate intensity resistance training group. The repetition times of each set are relatively moderate, 10-12 times. The rest time between sets is relatively moderate, 1-2 minutes. The relative exercise volume of this group was consistent with that of other experimental groups chest press, lat pull down, shoulder press and square, which are all trained through the multi-functional Smith machine. Bicep curl and triceps extension are operated by purchasing dumbbells with different weights. Leg extension and Leg curl use leg extension and curl machine Abdominal crunches and lower back exercises just do it by body weight training in yoga mat with abdominal curl and Lower back bridge |
| Low intensity of resistance training | Experimental | Device: resistance trainingThe intensity of 40-45% 1RM is used for low intensity resistance training group. The repetition times of each set are relatively more, 16-18 times. The rest time between groups is short, only about 1 minute, so that the participants can still maintain sufficient total exercise load under low intensity. chest press, lat pull down, shoulder press and square, which are all trained through the multi-functional Smith machine. Bicep curl and triceps extension are operated by purchasing dumbbells with different weights. Leg extension and Leg curl use leg extension and curl machine Abdominal crunches and lower back exercises just do it by body weight training in yoga mat with abdominal curl and Lower back bridge |
| Normal P.E. course | Other | Device: Normal P.E. courseCarry out general teaching content according to the college syllabus. |
Who may qualify
- Ages
- 18 to 22 years
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- Overweight or obese (BMI> 25)
- Female
- College students
- Healthy
Key exclusion criteria (2 listed)
- The subjects lack regular and active exercise program in last three months
- The subjects are not on a diet in last three months. c, Do not have regular menstrual cycle or approaching the normal menstrual cycle
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| resistance trainingresistance training lasts for 12 weeks, three times a week, one hour each time, and the program of resistance training in the experimental group was divided into 10 exercises: Chest press, Lat pull down, Shoulder press, Squat, Leg extension, Leg curl, Bicep curl, Triceps extension, abdominal crunches, lower back exercises. | Device | High intensity of resistance training, Low intensity of resistance training, Moderate intensity of resistance training |
| Normal P.E. courseCarry out general teaching content according to the college syllabus lasts for 12 weeks , three times a week, one hour each time, and the program of Normal P.E. course in the control group will be Physical recovery exercises, learn and practice queue formation, calisthenics, five step fists, long fist and Basic movements of Gymnastics gradually changed by week. | Device | Normal P.E. course |
Primary outcome
Change from baseline BMI at 6 weeks and 12 weeks.
Time frame: Pretest: Before experiment; Mid-test: 6 weeks end; Post-test: 12 weeks end.
This parameter belongs to Obesity Degree.
Change from baseline body fat percentage at 6 weeks and 12 weeks.
Time frame: Pretest: Before experiment; Mid-test: 6 weeks end; Post-test: 12 weeks end.
This parameter belongs to Obesity Degree.
Change from baseline waist circumference at 6 weeks and 12 weeks.
Time frame: Pretest: Before experiment; Mid-test: 6 weeks end; Post-test: 12 weeks end.
This parameter belongs to Obesity Degree.
Change from baseline energy intake at 6 weeks and 12 weeks.
Time frame: Pretest: Before experiment; Mid-test: 6 weeks end; Post-test: 12 weeks end.
This parameter will be recorded by Quantitative Daily Dietary Intake (QDI): three multiple-pass 24-hr recalls collected at each assessment time point by a research dietitian/technician. Analysis by Food Processor Nutrition Analysis Software (Version 9.6, 2005, ESHA Research, Salem, OR): recalls are analysed for calorie and macronutrient content
Change from baseline hunger at 6 weeks and 12 weeks.
Time frame: Pretest: Before experiment; Mid-test: 6 weeks end; Post-test: 12 weeks end.
This parameter will be test by 100-mm visual analogue scale (VAS): test at 6:00-8:00 am following a 10h overnight fast, rate perceive appetite firstly. Then provide with a standardised caloric stimulus, at 30, 60, 90 and 120min post consumption rate perceived appetite again (r = 0.42 - 0.85). At every time point, both lengths of VAS 100 mm were used to record desire to eat, hunger, fullness, and prospective food consumption. The four standardized questions were: (i) how strong is your desire to eat? ("very weak" to "very strong"), (ii) how hungry do you feel? ("not hungry at all" to "as hungry as I've ever felt"), (iii) how full do you feel? ("not full at all" to "very full"), and (iv) how much food do you think you can eat? (Prospective food consumption; "nothing at all" to "a large amount") .
Change from baseline fullness at 6 weeks and 12 weeks.
Time frame: Pretest: Before experiment; Mid-test: 6 weeks end; Post-test: 12 weeks end.
This parameter will be test by 100-mm visual analogue scale (VAS): test at 6:00-8:00 am following a 10h overnight fast, rate perceive appetite firstly. Then provide with a standardised caloric stimulus, at 30, 60, 90 and 120min post consumption rate perceived appetite again (r = 0.42 - 0.85). At every time point, both lengths of VAS 100 mm were used to record desire to eat, hunger, fullness, and prospective food consumption. The four standardized questions were: (i) how strong is your desire to eat? ("very weak" to "very strong"), (ii) how hungry do you feel? ("not hungry at all" to "as hungry as I've ever felt"), (iii) how full do you feel? ("not full at all" to "very full"), and (iv) how much food do you think you can eat? (Prospective food consumption; "nothing at all" to "a large amount") .
Change from baseline desire to eat at 6 weeks and 12 weeks.
Time frame: Pretest: Before experiment; Mid-test: 6 weeks end; Post-test: 12 weeks end.
This parameter will be test by 100-mm visual analogue scale (VAS): test at 6:00-8:00 am following a 10h overnight fast, rate perceive appetite firstly. Then provide with a standardised caloric stimulus, at 30, 60, 90 and 120min post consumption rate perceived appetite again (r = 0.42 - 0.85). At every time point, both lengths of VAS 100 mm were used to record desire to eat, hunger, fullness, and prospective food consumption. The four standardized questions were: (i) how strong is your desire to eat? ("very weak" to "very strong"), (ii) how hungry do you feel? ("not hungry at all" to "as hungry as I've ever felt"), (iii) how full do you feel? ("not full at all" to "very full"), and (iv) how much food do you think you can eat? (Prospective food consumption; "nothing at all" to "a large amount") .
Change from baseline prospective food consumption at 6 weeks and 12 weeks.
Time frame: Pretest: Before experiment; Mid-test: 6 weeks end; Post-test: 12 weeks end.
This parameter will be test by 100-mm visual analogue scale (VAS): test at 6:00-8:00 am following a 10h overnight fast, rate perceive appetite firstly. Then provide with a standardised caloric stimulus, at 30, 60, 90 and 120min post consumption rate perceived appetite again (r = 0.42 - 0.85). At every time point, both lengths of VAS 100 mm were used to record desire to eat, hunger, fullness, and prospective food consumption. The four standardized questions were: (i) how strong is your desire to eat? ("very weak" to "very strong"), (ii) how hungry do you feel? ("not hungry at all" to "as hungry as I've ever felt"), (iii) how full do you feel? ("not full at all" to "very full"), and (iv) how much food do you think you can eat? (Prospective food consumption; "nothing at all" to "a large amount") .
Change from baseline glucose at 6 weeks and 12 weeks.
Time frame: Pretest: Before experiment; Mid-test: 6 weeks end; Post-test: 12 weeks end.
Blood is collected into Vacutainers (BectonDickinson, Franklin Lakes, NJ) containing SST Gel (Becton Dickinson), Ethylenediaminetetraacetic acid(EDTA), or heparin and is immediately placed on ice and centrifuged (4 C, 1500g, 15 min). The serum or plasma obtained is stored in multiple aliquots at 75 C until assayed (in duplicate). Glucose is determined by the glucose oxidase method (Sigma-Aldrich Corp; 3.8% and 4.9% inter- and intraassay coefficients of variation) (70～140mg/dl or 3.9～7.8mmol/l)
Change from baseline leptin at 6 weeks and 12 weeks.
Time frame: Pretest: Before experiment; Mid-test: 6 weeks end; Post-test: 12 weeks end.
Blood is collected into Vacutainers (BectonDickinson, Franklin Lakes, NJ) containing Serum-separating tube(SST) Gel (Becton Dickinson), EDTA, or heparin and is immediately placed on ice and centrifuged (4 C, 1500g, 15 min). The serum or plasma obtained is stored in multiple aliquots at 75 C until assayed (in duplicate). Serum leptin is determined by an ELISA with a commercially available kit (EIA-2395, DRG, Marburg, Germany; 5.9% intraassay precision; 6.8% interassay accuracy; sensitivity of 0.5ng/ml).
Change from baseline adiponectin at 6 weeks and 12 weeks.
Time frame: Pretest: Before experiment; Mid-test: 6 weeks end; Post-test: 12 weeks end.
Blood is collected into Vacutainers (BectonDickinson, Franklin Lakes, NJ) containing SST Gel (Becton Dickinson), EDTA, or heparin and is immediately placed on ice and centrifuged (4 C, 1500g, 15 min). The serum or plasma obtained is stored in multiple aliquots at 75 C until assayed (in duplicate). Plasma adiponectin is analysed with a commercially available radioimmunoassay (RIA) (Linco Research, Inc., St. Charles, mo; 6.9% intraassay precision; 7.8% interassay accuracy; sensitivity of 0.5ng/ml.) (3~30μg/mL).
Change from baseline NPY at 6 weeks and 12 weeks.
Time frame: Pretest: Before experiment; Mid-test: 6 weeks end; Post-test: 12 weeks end.
Blood is collected into Vacutainers (BectonDickinson, Franklin Lakes, NJ) containing SST Gel (Becton Dickinson), EDTA, or heparin and is immediately placed on ice and centrifuged (4 C, 1500g, 15 min). The serum or plasma obtained is stored in multiple aliquots at 75 C until assayed (in duplicate). Neuropeptide Y is measured by Liquid Chromatography with tandem mass spectrometry (LC-MS/MS) (NPY; Phoenix Europe Gesellschaft mit beschränkter Haftung (GmbH), Karlsruhe, Germany; Sensitivity of 0.13 ng/ml; Intra-assay variability <5%) (51.23～209.65 pg/ml).
Change from baseline Insulin at 6 weeks and 12 weeks.
Time frame: Pretest: Before experiment; Mid-test: 6 weeks end; Post-test: 12 weeks end.
Blood is collected into Vacutainers (BectonDickinson, Franklin Lakes, NJ) containing SST Gel (Becton Dickinson), EDTA, or heparin and is immediately placed on ice and centrifuged (4 C, 1500g, 15 min). The serum or plasma obtained is stored in multiple aliquots at 75 C until assayed (in duplicate). Insulin is measured with an immunoassay (Access Immunoassay System, Beckman Coulter, Fullerton, California (CA); 4.9% intraassay precision; 3.8% interassay accuracy; sensitivity of 0.5 μu/ml) (60-100mg/dl).
Change from baseline meal-time at 6 weeks and 12 weeks.
Time frame: Pretest: Before experiment; Mid-test: 6 weeks end; Post-test: 12 weeks end.
This parameter record by Quantitative Daily Dietary Intake (QDI): three multiple-pass 24-hr recalls collected at each assessment time point by a research dietitian/technician. Analysis by Food Processor Nutrition Analysis Software (Version 9.6, 2005, ESHA Research, Salem, OR): recalls are analysed for the percentage of day and night total kcals intake separately.
Change from baseline stress of eating at 6 weeks and 12 weeks.
Time frame: Pretest: Before experiment; Mid-test: 6 weeks end; Post-test: 12 weeks end.
This parameter measured by The Salzburg Stress Eating Scale (SSES) which is the first to specifically address the relationship of stress experiences and coping failure on the one hand and increases or decreases in food intake on the other hand. Higher SSES scores indicate eating more when stressed, while lower scores indicate eating less when stressed.
Change from baseline physical activity level at 6 weeks and 12 weeks.
Time frame: Pretest: Before experiment; Mid-test: 6 weeks end; Post-test: 12 weeks end.
This parameter measured by Global Physical Activity Questionnaire (GPAQ). The GPAQ covers several components of physical activity, such as intensity, duration, and frequency, and it assesses three domains in which physical activity is performed (occupational physical activity, transport-related physical activity, and physical activity during discretionary or leisure time) comprising 16 questions (P1-P16). Since it was developed by World Health Organization (WHO) in 2002, the GPAQ has undergone a research program which shows that it is valid and reliable. It has become the most common tool in diagnostic and evaluation studies of physical activity globally.
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 7 Sep 2022.
- Results publication: PubMed 22525775Bales CW, Hawk VH, Granville EO, Rose SB, Shields T, Bateman L, Willis L, Piner LW, Slentz CA, Houmard JA, Gallup D, Samsa GP, Kraus WE. Aerobic and resistance training effects on energy intake: the STRRIDE-AT/RT study. Med Sci Sports Exerc. 2012 Oct;44(10):2033-9. doi: 10.1249/MSS.0b013e318259479a.
- Derived from this study: PubMed 40520279Wang Q, Xiao WS, Danaee M, Geok SK, Gan WY, Zhu WL, Mai YQ. Impact of resistance training intensity on body composition and nutritional intake among college women with overweight and obesity: a cluster randomized controlled trial. Front Public Health. 2025 May 30;13:1589036. doi: 10.3389/fpubh.2025.1589036. eCollection 2025.
- Description This article is from National Library of MediniceLink provided by the sponsor.
- Individual participant dataSharing planned: No. Because this is my doctoral thesis and it has certain confidentiality, I won't share it until I finish my doctoral thesis
Related trials for Overweight
RecruitingObservational study
Endoscopic Sleeve Gastroplasty (ESG) Prospective Trial for Obesity (EGO-Trial)
Obesity
Active, not recruitingPhase 4
Effects of Sequential Therapy With Mexidol® (Intravenous) and Mexidol® FORTE 250 (Oral) on Functional Brain Activity Assessed by Functional Magnetic Resonance Imaging and Biochemical Parameters in Patients With Chronic Cerebral Ischemia: A Comparison of Patients With and Without Metabolic Disorders
Metabolic Abnormalities, Obesity & Overweight
Recruiting
Exercise Training and Vitamin D Metabolism
Obesity & Overweight, Vitamin D
Recruiting
Metabolic Health, Bones and Nuts During Weight Loss in Adults
Weight Loss, Bone Density
Active, not recruiting
Effect of Probiotics on Insulin Sensitivity in Overweight and Obese Pregnancy
Obesity & Overweight, Gestational Diabetes Mellitus (GDM)
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Qiang Wang, Doctor principal investigator
Universiti Putra Malaysia
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing resistance training and Normal P.E. course in people with Overweight and Obese, run by Universiti Putra Malaysia at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 7 Sep 2022. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change from baseline BMI at 6 weeks and 12 weeks. (time frame: Pretest: Before experiment; Mid-test: 6 weeks end; Post-test: 12 weeks end.). The study lists 16 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT05530629, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 7 Sep 2022.