Diet QualityNCT05537337
Understanding Food Choices (Aim 2)
A study testing Multicomponent Intervention in people with Diet Quality, run by Duke-NUS Graduate Medical School at 1 site in Singapore.
Trial summary
This study aims to use the Multiphase Optimization Strategy (MOST) to build and optimize a multicomponent intervention that improves diet quality. The investigators have evaluated the effects of evidence-based public health interventions on consumers' diet quality via a web-based grocery store "NUSMart" as part of Aim… Read more about this study
- Who is it for?
- Ages 21 years and olderHealthy volunteers can take part
- Conditions the study is for
- Diet Quality
- What is being tested?
- Multicomponent Intervention
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 487 participants
- Where
- 1 siteSingapore
- Study dates
- 3 Jan 2023to 16 Oct 2023
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 21 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Singapore resident
- Age 21 and above
- Must be the primary weekly grocery shopper in their household
Who cannot join
- Non-Singapore resident
- Less than 21 years old
- Non-primary grocery shopper in their household
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Multiphase Optimal Strategy To Improve Diet Quality-MOSTDQ (Aim 2)
This study aims to use the Multiphase Optimization Strategy (MOST) to build and optimize a multicomponent intervention that improves diet quality. The investigators have evaluated the effects of evidence-based public health interventions on consumers' diet quality via a web-based grocery store "NUSMart" as part of Aim 1 of this study. Considering that the goal is to identify promising interventions that may optimize online grocery platforms, the investigators used Aim 1's results to assemble a multicomponent intervention that would significantly affect diet quality: a combination of three behavioral nudges that include food labels \& real-time feedback, ordering, and healthier substitute offers (a subset of the interventions examined in Aim 1). Aim 2 study aims to rigorously evaluate this multicomponent intervention.
Read the detailed description
The important role that diet plays in health and disease is well established. Excessive intake of energy, saturated fat and sodium increase the risk of heart disease, diabetes and certain cancers. As a result, interventions aimed at encouraging healthier food consumption have been pursued by many countries. These can be broadly grouped into the following categories: price manipulations, food labelling, and behavioral nudges.
No study has previously assessed the potentially interactive effects of a multicomponent intervention that incorporates the strongest features of each intervention component while discarding those that do not meaningfully contribute to healthier consumption. That is the goal of this effort.
At part of the first stage of the MOST framework (Aim 1), the investigators evaluated the effects of evidence-based public health interventions on consumers' diet quality on a web-based grocery store "NUSMart". The investigators focused on the following four interventions: 1. Explicit Tax, 2. Food labels (with the summary of healthiness of shopping baskets \& targets), 3. Ordering and 4. Within Group Healthier Substitution. Based on the study results, the investigators assembled a multicomponent intervention that consists of a subset of the above four interventions that may optimize online grocery platforms in terms of diet improvement.
The multicomponent intervention consists of the following components:
- Food labels (with the summary of healthiness of shopping baskets \& targets)- Food labels, called Nutri-Traffic-Lights (NTL), indicating whether food and beverage products were healthy, unhealthy or somewhere in between were designed for all products on NUSMart based on the Nutri-Score Nutrition Scoring System. These were supplemented with a video explaining the labels and a dynamic pie chart indicating the overall nutritional quality of the shopper's basket (updated in real time) known as MyCart summary.
- Ordering- Healthier products, in terms of Nutri-Score Points, were displayed first within each category and subcategory.
- Within Group Healthier Substitution- At checkout, up to 4 healthier substitutes were suggested for products in the shopper's cart based on the Nutri-Score Points of these products. Substitutes were from the same category as the product that was added to cart and were close to the original product in terms of price as well.
In this study (Aim 2), using a 2-arm randomized controlled trial, the investigators will test whether the assembled multicomponent intervention has a sustained positive effect on diet quality over 3 purchases over a 3-5-week period, wherein the purchased foods are delivered to the participants' homes.
Over the course of the study, participants will log into the NUSMart website once a week and will be asked to purchase their weekly groceries with a minimum spend of $59. Each participant will therefore shop a total of 3 times using the same version of NUSMart randomly assigned to them, during the study.
The investigators' hypotheses about the effects of the multicomponent intervention on diet quality, measured by the weighted (by the number of servings) average Nutri-Score Points (primary) of finalized shopping baskets, are as follows:
- The multicomponent intervention will significantly improve diet quality as measured by the weighted Nutri-Score Points (primary), calories, sodium, sugar, and saturated fat per serving, which will be calculated based on all purchased products' total nutritional value.
- The improvements in diet quality will be sustained through repeated shops where food is actually delivered, thus making it more likely that results are externally valid.
- Conditions
- Diet Quality
- Being tested
- Multicomponent Intervention
- Keywords
- Multicomponent Intervention, Multiphase Optimization Strategy, Food Labels, Food Repositioning, Within-group Substitutes, Randomized Control Trial (RCT)
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Multicomponent InterventionBehavioural
The multicomponent intervention consists of the following components (already described in the detailed description section):
- Food labels (with the summary of healthiness of shopping baskets \& targets)
- Ordering
- Within Group Healthier Substitution
| Study group | Role | What they receive |
|---|---|---|
| Arm 1 (Control Arm) | No intervention | Participants will experience an unmodified version of NUSMart that is designed to replicate the traditional shopping experience of any online grocery shopping platform with details such as item description, brand, price, image, nutritional information etc. |
| Arm 2 (Multicomponent Intervention Arm) | Experimental | Participants will experience a modified version of NUSMart with the multicomponent intervention enabled. This intervention consists of a subset of the combined interventions tested in Aim 1 namely, 1. Food labels (with the summary of healthiness of shopping baskets \& targets), 2. Ordering and 3. Within Group Healthier Substitution. Receives: Behavioral: Multicomponent Intervention |
What is being measured
The primary outcome is the main question the study is designed to answer.
Diet Quality
Diet quality measured by the weighted (by the number of servings) average of all purchased products' Nutri-Score Points for the shopping trip. Nutri-Score Points is an individual dietary index based on the British Food Standard Agency Nutrient Profiling System. Nutri-Score points are calculated by scoring food and beverage products on a scale from -15 (healthiest) to 40 (least healthy) by subtracting the sum of Nutri-Score sub-points for healthier components (e.g., fiber, protein, percentage of fruits \& vegetables) from the sum of Nutri-Score sub-points for less healthy components (e.g., energy, sugar, sodium, saturated fat). The final non-numeric grade, A to E, is determined based on carefully designed thresholds for these resulting Nutri-Score Points.
Measured: After completion of data collection, an average of about 14 months
Secondary outcomes (2)
Nutrients per serving
Average calories, sodium, sugar, and saturated fat per serving, which will be calculated based on all purchased products' total nutritional value.
Measured: After completion of data collection, an average of about 14 months
Proportion of products for each Nutri-Traffic-Light (NTL) classification
The proportion of products eligible for each of the 3 classifications of the NTL (i.e., the green circle, the amber circle and the red stop-sign) respectively, of the purchased products.
Measured: After completion of data collection, an average of about 14 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 Sep 2022
- Study start3 Jan 2023
- Primary completion16 Oct 2023
- Study completion16 Oct 2023
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Diet QualityStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 487 participants (actual)
Sponsor and investigators
- Lead sponsor
- Duke-NUS Graduate Medical School
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Eric A. Finkelstein, Duke-NUS Graduate Medical School
- Investigators
- Eric A Finkelstein, PhD MHA, Principal investigator, Duke-NUS Graduate Medical School
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05537337
- Sponsor's protocol ID
- MOH-000263 (Aim 2)
- Status last verified
- Jul 2024
- First submitted
- 8 Sep 2022
- Last updated
- 31 Jul 2024
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Publications
Shin S, Xiaoxi Y, Chakraborty B, Finkelstein EA. A Randomized Trial Using an Online Grocery Store to Evaluate a Multicomponent Digital Intervention to Improve Diet Quality. Am J Prev Med. 2025 Jul;69(1):107622. doi: 10.1016/j.amepre.2025.03.002. Epub 2025 Mar 20.
PubMed 40120994
Study at a glance
From the registry record, last updated by the sponsor on 31 Jul 2024. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Multiphase Optimal Strategy To Improve Diet Quality-MOSTDQ (Aim 2)
- ClinicalTrials.gov ID
- NCT05537337
- Acronym / sponsor ID
- MOH-000263 (Aim 2)
- Conditions
- Diet Quality
- Keywords
- Multicomponent Intervention, Multiphase Optimization Strategy, Food Labels, Food Repositioning, Within-group Substitutes, Randomized Control Trial (RCT)
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 487 participants (actual)
- Lead sponsor
- Duke-NUS Graduate Medical SchoolUniversity, hospital or other
- Study start
- 3 Jan 2023 (actual)
- Primary completion
- 16 Oct 2023 (actual)
- Study completion
- 16 Oct 2023 (actual)
- First posted
- 13 Sep 2022 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to use the Multiphase Optimization Strategy (MOST) to build and optimize a multicomponent intervention that improves diet quality. The investigators have evaluated the effects of evidence-based public health interventions on consumers' diet quality via a web-based grocery store "NUSMart" as part of Aim 1 of this study. Considering that the goal is to identify promising interventions that may optimize online grocery platforms, the investigators used Aim 1's results to assemble a multicomponent intervention that would significantly affect diet quality: a combination of three behavioral nudges that include food labels \& real-time feedback, ordering, and healthier substitute offers (a subset of the interventions examined in Aim 1). Aim 2 study aims to rigorously evaluate this multicomponent intervention.
Detailed description
The important role that diet plays in health and disease is well established. Excessive intake of energy, saturated fat and sodium increase the risk of heart disease, diabetes and certain cancers. As a result, interventions aimed at encouraging healthier food consumption have been pursued by many countries. These can be broadly grouped into the following categories: price manipulations, food labelling, and behavioral nudges.
No study has previously assessed the potentially interactive effects of a multicomponent intervention that incorporates the strongest features of each intervention component while discarding those that do not meaningfully contribute to healthier consumption. That is the goal of this effort.
At part of the first stage of the MOST framework (Aim 1), the investigators evaluated the effects of evidence-based public health interventions on consumers' diet quality on a web-based grocery store "NUSMart". The investigators focused on the following four interventions: 1. Explicit Tax, 2. Food labels (with the summary of healthiness of shopping baskets \& targets), 3. Ordering and 4. Within Group Healthier Substitution. Based on the study results, the investigators assembled a multicomponent intervention that consists of a subset of the above four interventions that may optimize online grocery platforms in terms of diet improvement.
The multicomponent intervention consists of the following components:
- Food labels (with the summary of healthiness of shopping baskets \& targets)- Food labels, called Nutri-Traffic-Lights (NTL), indicating whether food and beverage products were healthy, unhealthy or somewhere in between were designed for all products on NUSMart based on the Nutri-Score Nutrition Scoring System. These were supplemented with a video explaining the labels and a dynamic pie chart indicating the overall nutritional quality of the shopper's basket (updated in real time) known as MyCart summary.
- Ordering- Healthier products, in terms of Nutri-Score Points, were displayed first within each category and subcategory.
- Within Group Healthier Substitution- At checkout, up to 4 healthier substitutes were suggested for products in the shopper's cart based on the Nutri-Score Points of these products. Substitutes were from the same category as the product that was added to cart and were close to the original product in terms of price as well.
In this study (Aim 2), using a 2-arm randomized controlled trial, the investigators will test whether the assembled multicomponent intervention has a sustained positive effect on diet quality over 3 purchases over a 3-5-week period, wherein the purchased foods are delivered to the participants' homes.
Over the course of the study, participants will log into the NUSMart website once a week and will be asked to purchase their weekly groceries with a minimum spend of $59. Each participant will therefore shop a total of 3 times using the same version of NUSMart randomly assigned to them, during the study.
The investigators' hypotheses about the effects of the multicomponent intervention on diet quality, measured by the weighted (by the number of servings) average Nutri-Score Points (primary) of finalized shopping baskets, are as follows:
- The multicomponent intervention will significantly improve diet quality as measured by the weighted Nutri-Score Points (primary), calories, sodium, sugar, and saturated fat per serving, which will be calculated based on all purchased products' total nutritional value.
- The improvements in diet quality will be sustained through repeated shops where food is actually delivered, thus making it more likely that results are externally valid.
Study design
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Arm 1 (Control Arm) | No intervention | –Participants will experience an unmodified version of NUSMart that is designed to replicate the traditional shopping experience of any online grocery shopping platform with details such as item description, brand, price, image, nutritional information etc. |
| Arm 2 (Multicomponent Intervention Arm) | Experimental | Behavioral: Multicomponent InterventionParticipants will experience a modified version of NUSMart with the multicomponent intervention enabled. This intervention consists of a subset of the combined interventions tested in Aim 1 namely, 1. Food labels (with the summary of healthiness of shopping baskets \& targets), 2. Ordering and 3. Within Group Healthier Substitution. |
Who may qualify
- Ages
- 21 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Singapore resident
- Age 21 and above
- Must be the primary weekly grocery shopper in their household
Key exclusion criteria (3 listed)
- Non-Singapore resident
- Less than 21 years old
- Non-primary grocery shopper in their household
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Multicomponent InterventionThe multicomponent intervention consists of the following components (already described in the detailed description section): 1. Food labels (with the summary of healthiness of shopping baskets \& targets) 2. Ordering 3. Within Group Healthier Substitution | Behavioural | Arm 2 (Multicomponent Intervention Arm) |
Primary outcome
Diet Quality
Time frame: After completion of data collection, an average of about 14 months
Diet quality measured by the weighted (by the number of servings) average of all purchased products' Nutri-Score Points for the shopping trip. Nutri-Score Points is an individual dietary index based on the British Food Standard Agency Nutrient Profiling System. Nutri-Score points are calculated by scoring food and beverage products on a scale from -15 (healthiest) to 40 (least healthy) by subtracting the sum of Nutri-Score sub-points for healthier components (e.g., fiber, protein, percentage of fruits \& vegetables) from the sum of Nutri-Score sub-points for less healthy components (e.g., energy, sugar, sodium, saturated fat). The final non-numeric grade, A to E, is determined based on carefully designed thresholds for these resulting Nutri-Score Points.
2 secondary outcomes
Nutrients per serving
Time frame: After completion of data collection, an average of about 14 months
Proportion of products for each Nutri-Traffic-Light (NTL) classification
Time frame: After completion of data collection, an average of about 14 months
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 31 Jul 2024.
- Derived from this study: PubMed 40120994Shin S, Xiaoxi Y, Chakraborty B, Finkelstein EA. A Randomized Trial Using an Online Grocery Store to Evaluate a Multicomponent Digital Intervention to Improve Diet Quality. Am J Prev Med. 2025 Jul;69(1):107622. doi: 10.1016/j.amepre.2025.03.002. Epub 2025 Mar 20.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Eric A Finkelstein, PhD MHA principal investigator
Duke-NUS Graduate Medical School
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Multicomponent Intervention in people with Diet Quality, run by Duke-NUS Graduate Medical School at 1 site in Singapore.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 31 Jul 2024. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Singapore. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Diet Quality (time frame: After completion of data collection, an average of about 14 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT05537337, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 31 Jul 2024; AzTrials last refreshed its copy on 28 Oct 2026.