Myofascial Pain SyndromeNCT05565053
Bilateral Erector Spinae Plane Block for Myofascial Pain Syndrome
A study testing Bilateral thoracal erector spinae plane block and Trapezius muscle trigger point injection in people with Myofascial Pain Syndrome, run by Istanbul University at 1 site in Turkey (Türkiye).
Trial summary
The investigators aimed to evaluate the effectiveness of bilateral erector spina plane block application in myofascial pain syndrome. Read more about this study
- Who is it for?
- Ages 18 to 65 years
- Conditions the study is for
- Myofascial Pain Syndrome
- What is being tested?
- Bilateral thoracal erector spinae plane block and Trapezius muscle trigger point injection
- Type of treatment
- Injection or infusion, Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 25 Jul 2021to 1 Mar 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Get a myofascial pain syndrome diagnosis
- No invasive procedure for myofascial pain syndrome in the last 1 month
- Signing the informed consent form
Who cannot join
- Cervical disc herniation
- Neck/shoulder, thoracal trauma or operation history
- Malignancy
- Kyphoscoliosis
- Inflammatory diseases (Rheumatoid arthritis, ankylosing spondylitis...)
- Congenital vertebral anomalies
Show all 12Show fewer
- Pregnancy
- Mental, psychogenic disorder
- Hematological diseases that cause bleeding and coagulation disorders
- Use of antiplatelet, anticoagulant and drugs that cause bleeding tendency
- Severe systemic infection such as sepsis and local infection at the intervention site
- Having an allergy to any of the drugs to be used
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Istanbul University Istanbul Faculty of Medicine
Istanbul, 34104
About this study
The investigators aimed to evaluate the effectiveness of bilateral erector spina plane block application in myofascial pain syndrome.
Read the detailed description
The investigators aimed to evaluate the effectiveness of bilateral erector spina plane block application in myofascial pain syndrome by comparing trigger point injection. Group 1 received erector spinae plane block, and group 2 received trigger point injection both administered in two weekly sessions. Before the application, one week after application and one month after application the investigators aimed to compare pressure pain threshold with algometer, visual analog scale score, neck disability index score, for the two groups. Each group has 30 participants, total 60 participants included this study. The investigators planned to show that bilateral erector spinae plane block can be used as an effective and safe method in the treatment of myofascial pain syndrome, since it is easier to apply than other invasive procedures used in the treatment and has a very low complication profile.
- Conditions
- Myofascial Pain Syndrome
- Being tested
- Bilateral thoracal erector spinae plane block, Trapezius muscle trigger point injection
- Keywords
- Erector spinae plane block, Myofascial pain syndrome, Trigger point, Algometer, Visual Analog Scale, Pain
- Medical subject headings
- Myofascial Pain Syndromes, Pain
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Bilateral thoracal erector spinae plane blockProcedure or surgery
Bilateral upper thoracal erector spinae plane block with ultrasound
Trapezius muscle trigger point injectionProcedure or surgery
Trapezius muscle trigger point injection
| Study group | Role | What they receive |
|---|---|---|
| Bilateral Erector Spinae Plane Block | Active comparator | Bilateral Erector Spinae Plane Block Receives: Procedure: Bilateral thoracal erector spinae plane block |
| Trigger Point Injection | Active comparator | Trapezius muscle Trigger Point Injection Receives: Procedure: Trapezius muscle trigger point injection |
What is being measured
The primary outcome is the main question the study is designed to answer.
Comparison of the effectiveness of the two interventions (trigger point injection versus Erector spinae plane block) assessed by Visual analog scale (VAS):
The classic interventional treatment of myofascial back pain is trigger point injection. In addition, erector spina plan block has been applied in recent years as an interventional procedure that provides analgesia in the same region and is thought to have a long duration of action. Visual analog scale (VAS): Using a ruler, the score is determined by measuring the distance (mm) on the 10-cm line between the "no pain" anchor and the patient's mark, providing a range of scores from 0-100. A higher score indicates greater pain intensity.
Measured: Baseline
Comparison of the effectiveness of the two interventions (trigger point injection versus Erector spinae plane block) assessed by Visual analog scale (VAS):
The classic interventional treatment of myofascial back pain is trigger point injection. In addition, erector spina plan block has been applied in recent years as an interventional procedure that provides analgesia in the same region and is thought to have a long duration of action. Visual analog scale (VAS): Using a ruler, the score is determined by measuring the distance (mm) on the 10-cm line between the "no pain" anchor and the patient's mark, providing a range of scores from 0-100. A higher score indicates greater pain intensity.
Measured: 1. month
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted4 Oct 2022
- Study start25 Jul 2021
- Primary completion1 Jan 2025
- Study completion1 Mar 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Myofascial Pain SyndromeStudies of the same condition, open and under way.
- More trials run by Istanbul UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Screening
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Comparing the efficacy of erector spina plan block and trigger point injection in patients with myofascial pain syndrome
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 60 participants (actual)
Sponsor and investigators
- Lead sponsor
- Istanbul University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Halil Cetingok, Istanbul University
- Investigators
- Halil Çetingök, Study director, Istanbul University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05565053
- Sponsor's protocol ID
- 2019/725
- Status last verified
- May 2026
- First submitted
- 5 Aug 2022
- Last updated
- 15 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 15 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Bilateral Erector Spinae Plane Block for Myofascial Pain Syndrome
- ClinicalTrials.gov ID
- NCT05565053
- Acronym / sponsor ID
- 2019/725
- Conditions
- Myofascial Pain Syndrome
- Keywords
- Erector spinae plane block, Myofascial pain syndrome, Trigger point, Algometer, Visual Analog Scale, Pain
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 60 participants (actual)
- Lead sponsor
- Istanbul UniversityUniversity, hospital or other
- Study start
- 25 Jul 2021 (actual)
- Primary completion
- 1 Jan 2025 (actual)
- Study completion
- 1 Mar 2026 (actual)
- First posted
- 4 Oct 2022 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The investigators aimed to evaluate the effectiveness of bilateral erector spina plane block application in myofascial pain syndrome.
Detailed description
The investigators aimed to evaluate the effectiveness of bilateral erector spina plane block application in myofascial pain syndrome by comparing trigger point injection. Group 1 received erector spinae plane block, and group 2 received trigger point injection both administered in two weekly sessions. Before the application, one week after application and one month after application the investigators aimed to compare pressure pain threshold with algometer, visual analog scale score, neck disability index score, for the two groups. Each group has 30 participants, total 60 participants included this study. The investigators planned to show that bilateral erector spinae plane block can be used as an effective and safe method in the treatment of myofascial pain syndrome, since it is easier to apply than other invasive procedures used in the treatment and has a very low complication profile.
Study design
- Primary purpose
- Screening
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
- Model description
- Comparing the efficacy of erector spina plan block and trigger point injection in patients with myofascial pain syndrome
| Arm | Type | Receives |
|---|---|---|
| Bilateral Erector Spinae Plane Block | Active comparator | Procedure: Bilateral thoracal erector spinae plane blockBilateral Erector Spinae Plane Block |
| Trigger Point Injection | Active comparator | Procedure: Trapezius muscle trigger point injectionTrapezius muscle Trigger Point Injection |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Get a myofascial pain syndrome diagnosis
- No invasive procedure for myofascial pain syndrome in the last 1 month
- Signing the informed consent form
Key exclusion criteria (12 listed)
- Cervical disc herniation
- Neck/shoulder, thoracal trauma or operation history
- Malignancy
- Kyphoscoliosis
- Inflammatory diseases (Rheumatoid arthritis, ankylosing spondylitis...)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Bilateral thoracal erector spinae plane blockBilateral upper thoracal erector spinae plane block with ultrasound | Procedure or surgery | Bilateral Erector Spinae Plane Block |
| Trapezius muscle trigger point injectionTrapezius muscle trigger point injection | Procedure or surgery | Trigger Point Injection |
Primary outcome
Comparison of the effectiveness of the two interventions (trigger point injection versus Erector spinae plane block) assessed by Visual analog scale (VAS):
Time frame: Baseline
The classic interventional treatment of myofascial back pain is trigger point injection. In addition, erector spina plan block has been applied in recent years as an interventional procedure that provides analgesia in the same region and is thought to have a long duration of action. Visual analog scale (VAS): Using a ruler, the score is determined by measuring the distance (mm) on the 10-cm line between the "no pain" anchor and the patient's mark, providing a range of scores from 0-100. A higher score indicates greater pain intensity.
Comparison of the effectiveness of the two interventions (trigger point injection versus Erector spinae plane block) assessed by Visual analog scale (VAS):
Time frame: 1. month
The classic interventional treatment of myofascial back pain is trigger point injection. In addition, erector spina plan block has been applied in recent years as an interventional procedure that provides analgesia in the same region and is thought to have a long duration of action. Visual analog scale (VAS): Using a ruler, the score is determined by measuring the distance (mm) on the 10-cm line between the "no pain" anchor and the patient's mark, providing a range of scores from 0-100. A higher score indicates greater pain intensity.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 15 May 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Halil Çetingök study director
Istanbul University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Bilateral thoracal erector spinae plane block and Trapezius muscle trigger point injection in people with Myofascial Pain Syndrome, run by Istanbul University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 12 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 15 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Comparison of the effectiveness of the two interventions (trigger point injection versus Erector spinae plane block) assessed by Visual analog scale (VAS): (time frame: Baseline). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 15 May 2026.