Healthy AdultsNCT05567926
Acute Effects of Beetroot Juice on Isometric Knee Extension Strength, Explosive Strength and Local Muscular Endurance
A study testing Beetroot juice concentrate (140 ml) in people with Healthy Adults, run by University of Primorska at 1 site in Slovenia.
Trial summary
This is a double-blind placebo-controlled cross-over trial that aims to determine the acute effect of beetroot juice ingestion on isometric knee extension strength, explosive strength and local muscular endurance. Read more about this study
- Who is it for?
- Ages 18 to 30 yearsHealthy volunteers can take part
- Conditions the study is for
- Healthy Adults
- What is being tested?
- Beetroot juice concentrate (140 ml)
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 20 participants
- Where
- 1 siteSlovenia
- Study dates
- 1 Oct 2022to 17 Oct 2022
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 30 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Age between 18 and 30 years
- Physically active and healthy athletes (recreational or professional)
Who cannot join
- Cardiovascular, pulmonary, metabolic, neurological diseases and musculoskeletal injuries
- Smokers
- Consumption of drugs such as antacids and proton pump inhibitors in the previous 3 months
- Pregnant or breastfeeding women
- Beetroot allergic participants
Trial locations and contacts
1 site in 1 country.
Slovenia1 site
University of Primorska Faculty of Health Sciences
Izola, SI-6310
About this study
Official title: Acute Effects of Beetroot Juice Ingestion on Isometric Knee Extension Strength, Explosive Strength and Local Muscular Endurance
This is a double-blind placebo-controlled cross-over trial that aims to determine the acute effect of beetroot juice ingestion on isometric knee extension strength, explosive strength and local muscular endurance.
Read the detailed description
The study aims to determine whether concentrated beetroot juice has an acute effect on isometric strength of the knee muscles and the rate of force development in knee extension, as well as endurance of the same muscle. This will be a cross-over study. 20 subjects will be randomly selected to the experimental group or control group; after 1 week, participants will repeat the measurements in the other condition. Subjects will consume 140 ml of beetroot juice extract 2.5 hours before the measurement or placebo (140 ml of blackcurrant juice with added appropriate amount of sugar to equalize the carbohydrate value and lemon juice fort the taste). An isometric dynamometer will be used to measure the isometric strength of the knee extensors. Investigators will quantify peak force, rate of force development, endurance of knee extensors at 50 % of the maximal force, and the force recovery after a fatiguing protocol.
- Conditions
- Healthy Adults
- Being tested
- Beetroot juice concentrate (140 ml), Blackcurrant juice (placebo)
- Keywords
- isometric strength, beetroot, nitrates, local muscle endurance, supplementation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Beetroot juice concentrate (140 ml)Dietary supplement
A beetroot juice concentrate (140 ml) will be administered to participants in experimental conditions.
Blackcurrant juice (placebo)Dietary supplement
140 ml of blackcurrant juice with added appropriate amount of sugar to equalize the carbohydrate value and lemon juice fort the taste.
| Study group | Role | What they receive |
|---|---|---|
| Experimental condition, receiving beetroot juice supplement | Experimental | Participants will receive beetroot juice intervention in the experimental condition. Receives: Dietary Supplement: Beetroot juice concentrate (140 ml) |
| Placebo condition | Placebo comparator | Participants will receive placebo (blackcurrant juice) in the placebo condition Receives: Dietary Supplement: Blackcurrant juice (placebo) |
What is being measured
The primary outcome is the main question the study is designed to answer.
Knee extension strength
The peak force during maximal voluntary contraction of knee extensors
Measured: 2 hours after the ingestion of beetroot juice or placebo
Secondary outcomes (2)
Knee extension explosive strength
The rate of force development during maximal voluntary contraction of knee extensors
Measured: 2 hours after the ingestion of beetroot juice or placebo
Knee extension local muscle endurance
Time to failure of knee muscles at 50 % of maximal force
Measured: 2 hours after the ingestion of beetroot juice or placebo
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 Oct 2022
- Study start1 Oct 2022
- Primary completion15 Oct 2022
- Study completion17 Oct 2022
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Healthy AdultsStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Triple blind
- Who is masked
- Participant, Investigator, Outcomes assessor
- Enrolment
- 20 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Primorska
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Zala Jenko Praznikar, University of Primorska
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05567926
- Sponsor's protocol ID
- BEETROOT
- Status last verified
- Oct 2022
- First submitted
- 2 Oct 2022
- Last updated
- 19 Oct 2022
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 19 Oct 2022. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Acute Effects of Beetroot Juice Ingestion on Isometric Knee Extension Strength, Explosive Strength and Local Muscular Endurance
- ClinicalTrials.gov ID
- NCT05567926
- Acronym / sponsor ID
- BEETROOT
- Conditions
- Healthy Adults
- Keywords
- isometric strength, beetroot, nitrates, local muscle endurance, supplementation
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 20 participants (actual)
- Lead sponsor
- University of PrimorskaUniversity, hospital or other
- Study start
- 1 Oct 2022 (actual)
- Primary completion
- 15 Oct 2022 (actual)
- Study completion
- 17 Oct 2022 (actual)
- First posted
- 5 Oct 2022 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This is a double-blind placebo-controlled cross-over trial that aims to determine the acute effect of beetroot juice ingestion on isometric knee extension strength, explosive strength and local muscular endurance.
Detailed description
The study aims to determine whether concentrated beetroot juice has an acute effect on isometric strength of the knee muscles and the rate of force development in knee extension, as well as endurance of the same muscle. This will be a cross-over study. 20 subjects will be randomly selected to the experimental group or control group; after 1 week, participants will repeat the measurements in the other condition. Subjects will consume 140 ml of beetroot juice extract 2.5 hours before the measurement or placebo (140 ml of blackcurrant juice with added appropriate amount of sugar to equalize the carbohydrate value and lemon juice fort the taste). An isometric dynamometer will be used to measure the isometric strength of the knee extensors. Investigators will quantify peak force, rate of force development, endurance of knee extensors at 50 % of the maximal force, and the force recovery after a fatiguing protocol.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Triple blind (participant, investigator, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Experimental condition, receiving beetroot juice supplement | Experimental | Dietary Supplement: Beetroot juice concentrate (140 ml)Participants will receive beetroot juice intervention in the experimental condition. |
| Placebo condition | Placebo comparator | Dietary Supplement: Blackcurrant juice (placebo)Participants will receive placebo (blackcurrant juice) in the placebo condition |
Who may qualify
- Ages
- 18 to 30 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (2 listed)
- Age between 18 and 30 years
- Physically active and healthy athletes (recreational or professional)
Key exclusion criteria (5 listed)
- Cardiovascular, pulmonary, metabolic, neurological diseases and musculoskeletal injuries
- Smokers
- Consumption of drugs such as antacids and proton pump inhibitors in the previous 3 months
- Pregnant or breastfeeding women
- Beetroot allergic participants
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Beetroot juice concentrate (140 ml)A beetroot juice concentrate (140 ml) will be administered to participants in experimental conditions. | Dietary supplement | Experimental condition, receiving beetroot juice supplement |
| Blackcurrant juice (placebo)140 ml of blackcurrant juice with added appropriate amount of sugar to equalize the carbohydrate value and lemon juice fort the taste. | Dietary supplement | Placebo condition |
Primary outcome
Knee extension strength
Time frame: 2 hours after the ingestion of beetroot juice or placebo
The peak force during maximal voluntary contraction of knee extensors
2 secondary outcomes
Knee extension explosive strength
Time frame: 2 hours after the ingestion of beetroot juice or placebo
Knee extension local muscle endurance
Time frame: 2 hours after the ingestion of beetroot juice or placebo
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 Oct 2022.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Beetroot juice concentrate (140 ml) in people with Healthy Adults, run by University of Primorska at 1 site in Slovenia.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 19 Oct 2022. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Slovenia. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Knee extension strength (time frame: 2 hours after the ingestion of beetroot juice or placebo). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 Oct 2022.