GripNCT05594888
GRIP: Maximum Isometric Grip Strength Assessed With Three Different Hand-held Dynamometers
An observational study of Grip, run by Johannes Scherr at 1 site in Switzerland.
Trial summary
Maximum isometric grip strength (MIGS) is a cost-effective, easily accessible, valid and reliable outcome measure for assessing upper body strength in both, adults and children. The the JAMAR Hydraulic Hand Dynamometer is the current gold standard for measuring MIGS. Read more about this study
- Who is it for?
- Ages 10 years and olderHealthy volunteers can take part
- Conditions the study is for
- Grip
- How many people
- 520 participants
- Where
- 1 siteSwitzerland
- Study dates
- 17 Nov 2022to 31 Jan 2025
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 10 years and older
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Study population: Part 1: * Male and female volunteers (age 18-64 years) working at University Hospital Balgrist. * 40 participants: to exclude possible sex aspects, ratio ♀: ♂ = 1:1 Part 2: * Male and female volunteers (age ≥ 10 years). MIGS is used as a health indicator throughout different age- and sex groups. * 20 participants per age-group and sex with a total of 520 subjects are planned
Who may be able to join
- Male and female volunteers with age 18-64 years
- Body mass index < 30 kg/m2
- Informed consent signed
- Male and female volunteers with age ≥ 10 years
- Informed consent signed (if age < 14 years, signed by parents or legal guardians)
Who cannot join
- Disease or injury (e.g., musculoskeletal or neurological) that could affect upper extremity strength
- Physical impairment of the upper extremity (visible swelling or the presence of a splint or cast)
- Acute pain or infection
- Cognitive impairment (inability to understand and/or follow directions)
- Insufficient language of the German language
Trial locations and contacts
1 site in 1 country.
Switzerland1 site
University Hospital Balgrist
Zurich, Canton of Zurich, 8008
About this study
Official title: GRIP: Evaluation of the Comparability of the Maximum Isometric Grip Strength Measurement Assessed With the JAMAR© Hydraulic Hand Dynamometer, the JAMAR© Smart Hand Dynamometer and the Martin Vigorimeter
Maximum isometric grip strength (MIGS) is a cost-effective, easily accessible, valid and reliable outcome measure for assessing upper body strength in both, adults and children. The the JAMAR Hydraulic Hand Dynamometer is the current gold standard for measuring MIGS. For certain age- and activity-groups, alternative devices may be more appropriate. To date, the quality criteria (test-retest-reliability and validity) of the JAMAR Smart Hand Dynamometer and the Martin Vigorimeter compared to the current gold standard are not yet investigated. Furthermore, no reference values for different age-, sex-, or activity level groups exist with regard to underlying disease entities for these three devices.
Read the detailed description
This quality analysis of test-retest reliability and validity (PART 1) serves as a basis for a further sensitivity analysis, whereby in a second step, a database with valid personalised age-, sex- and activity-related reference values for the respective measurement instrument, considering chronic concomitant diseases, is to be generated. The objectives of this study are therefore to 1) assess the test-retest reliability (intrasubject and intersession) and validity of JAMAR© Hydraulic and JAMAR© Smart dynamometers and Martin Vigorimeter (PART 1) and 2) undertake a sensitivity analysis providing valid personalised reference values for precision medicine (PART 2).
Thus, no study has yet comprehensively investigated all relevant influencing factors in a single and thus homogeneous study setting, so bias can be expected from this alone. The findings of this two-step study should enable physicians and therapists to compare the grip strength measurements of their patients with normative values in relation to their age, sex and activity group, as well as to any underlying chronic diseases that may be present. This allows realistic treatment and training goals to be set and patient performance to be interpreted.
- Conditions
- Grip
- Keywords
- Maximum isometric grip strength, Hand-held dynamometer, Reference values, Physical therapy
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| PART 1- Group A | Male and female volunteers (age 18-64 years) working at University Hospital Balgrist. Assessment of validity and intrasubject reliability of maximum isometric grip strength assessed with: * JAMAR© Smart Dynamometer [kg] * JAMAR© Hydraulic Dynamometer [kg] * Martin Vigorimeter [kPa] | |
| PART 1 - Group B | Male and female volunteers (age 18-64 years) working at University Hospital Balgrist. Assessment of validity and intrasubject reliability and assessment of intersession reliability of maximum isometric grip strength assessed with: * JAMAR© Smart Dynamometer [kg] * JAMAR© Hydraulic Dynamometer [kg] * Martin Vigorimeter [kPa] | |
| PART 2 | Male and female volunteers (age ≥ 10 years). Maximum isometric grip strength is assessed (no intervention): * JAMAR© Smart Dynamometer [kg] * JAMAR© Hydraulic Dynamometer [kg] * Martin Vigorimeter [KPa] |
What is being measured
The primary outcome is the main question the study is designed to answer.
PART 1: Quality criteria: Intrasubject reliability
Test-retest reliability of the JAMAR© Smart Dynamometer, the JAMAR© Hydraulic Dynamometer and Martin Vigorimeter measuring MIGS will be assessed by intrasubject realiability.
--> 5 attempts per device and dominant/adominant hand will be measured.
Measured: 5 minutes
PART 1: Quality criteria: Intersession reliability
Test-retest reliability of the JAMAR© Smart Dynamometer, the JAMAR© Hydraulic Dynamometer and Martin Vigorimeter measuring MIGS will be assessed by intersession realiability.
--> 5 attempts per device and dominant/adominant hand at two different days will be measured.
Measured: 5 minutes
PART 1: Quality criteria: Validity
Validity of the JAMAR© Smart Dynamometer, the JAMAR© Hydraulic Dynamometer and Martin Vigorimeter measuring MIGS will be assessed by plotting the differences in grip force measurements of the 3 measurement devices against their means, with ± 1.96 SD as cut-off values (limits of agreement).
--> 5 attempts per device and dominant/adominant hand will be measured.
Measured: 5 minutes
PART 2: Comparability of MIGS measurement
Evaluation of comparability of MIGS measurement assessed with the JAMAR© Smart Dynamometer, the JAMAR© Hydraulic Dynamometer and the Martin Vigorimeter
-> Best out of 3 attempts per device and dominant/adominant hand
Measured: 10 minutes
Secondary outcomes (13)
PART 2: Age-specific refence values - JAMAR© Hydraulic
Age-specific refence values for MIGS assessed with the JAMAR© Hydraulic. Age is assessed by the number of years. Thirteen age groups are established with an increment of five to ten years: 10-14/15-19/20- 29/30-39/40-44/45-49/50-54/55-59/60-64/65-69/70-74/75-79/80+
Measured: 1 minute
PART 2: Age-specific refence values - JAMAR© Smart
Age-specific refence values for MIGS assessed with the JAMAR© Smart. Age is assessed by the number of years. Thirteen age groups are established with an increment of five to ten years: 10-14/15-19/20- 29/30-39/40-44/45-49/50-54/55-59/60-64/65-69/70-74/75-79/80+
Measured: 1 minute
PART 2: Age-specific refence values - Martin Vigorimeter
Age-specific refence values for MIGS assessed with the Martin Vigorimeter. Age is assessed by the number of years. Thirteen age groups are established with an increment of five to ten years: 10-14/15-19/20- 29/30-39/40-44/45-49/50-54/55-59/60-64/65-69/70-74/75-79/80+
Measured: 1 minute
PART 2: Sex-specific refence values - JAMAR© Hydraulic
Sex-specific refence values for MIGS assessed with the , JAMAR© Hydraulic. Sex is recorded as male or female (biological sex).
Measured: 0.5 minute
PART 2: Sex-specific refence values - JAMAR© Smart
Sex-specific refence values for MIGS assessed with the JAMAR© Smart. Sex is recorded as male or female (biological sex).
Measured: 0.5 minute
PART 2: Sex-specific refence values - Martin Vigorimeter
Sex-specific refence values for MIGS assessed with the Martin Vigorimeter. Sex is recorded as male or female (biological sex).
Measured: 0.5 minute
PART 2: Physical activity-specific reference values - JAMAR© Hydraulic
Physical activity-specific reference values for MIGS measurements assessed with the JAMAR© Hydraulic.
The IPAQ, the PAQ-A and the PAQ-C are used to assess individual levels of physical activity through all age groups. The IPAQ is a reliable and valid instrument that shows very good repeatability, was designed for people aged 18-65 years and is validated for persons aged 18-84 years. Adolescents between 15 and 18 years of age are assessed using the PAQ-A and children aged 10-14 years are assessed by the PAQ-C.
Measured: 2 minutes
PART 2: Physical activity-specific reference values - JAMAR© Smart
Physical activity-specific reference values for MIGS measurements assessed with the JAMAR© Smart.
The IPAQ, the PAQ-A and the PAQ-C are used to assess individual levels of physical activity through all age groups. The IPAQ is a reliable and valid instrument that shows very good repeatability, was designed for people aged 18-65 years and is validated for persons aged 18-84 years. Adolescents between 15 and 18 years of age are assessed using the PAQ-A and children aged 10-14 years are assessed by the PAQ-C.
Measured: 2 minutes
PART 2: Physical activity-specific reference values - Martin Vigorimeter
Physical activity-specific reference values for MIGS measurements assessed with the Martin Vigorimeter.
The IPAQ, the PAQ-A and the PAQ-C are used to assess individual levels of physical activity through all age groups. The IPAQ is a reliable and valid instrument that shows very good repeatability, was designed for people aged 18-65 years and is validated for persons aged 18-84 years. Adolescents between 15 and 18 years of age are assessed using the PAQ-A and children aged 10-14 years are assessed by the PAQ-C.
Measured: 2 minutes
PART 2: Refence values for subjects with different disease entities - JAMAR© Hydraulic
Refence values for subjects with different disease entities that might influence target value of MIGS measurement assessed with the JAMAR© Hydraulic
Any chronic disease entities that may be present, (possible chronic diseases according to organ class) are recorded:
- Pulmonary (e.g., COPD)
- Cardiac (e.g., CHF)
- Neurological (apoplexy, PNP)
- Gastroenterological (e.g., chronic gastritis)
- Gynaecological (e.g., endometriosis)
- Rheumatic (e.g., arthritis)
- Oncological
- Musculoskeletal (e.g., spine, lower extremities)
- Metabolic (e.g., diabetes mellitus).
Measured: 1 minute
PART 2: Refence values for subjects with different disease entities - JAMAR© Smart
Refence values for subjects with different disease entities that might influence target value of MIGS measurement assessed with the JAMAR© Smart
Any chronic disease entities that may be present, (possible chronic diseases according to organ class) are recorded:
- Pulmonary (e.g., COPD)
- Cardiac (e.g., CHF)
- Neurological (apoplexy, PNP)
- Gastroenterological (e.g., chronic gastritis)
- Gynaecological (e.g., endometriosis)
- Rheumatic (e.g., arthritis)
- Oncological
- Musculoskeletal (e.g., spine, lower extremities)
- Metabolic (e.g., diabetes mellitus).
Measured: 1 minute
PART 2: Refence values for subjects with different disease entities - Martin Vigorimeter.
Refence values for subjects with different disease entities that might influence target value of MIGS measurement assessed with the Martin Vigorimeter.
Any chronic disease entities that may be present, (possible chronic diseases according to organ class) are recorded:
- Pulmonary (e.g., COPD)
- Cardiac (e.g., CHF)
- Neurological (apoplexy, PNP)
- Gastroenterological (e.g., chronic gastritis)
- Gynaecological (e.g., endometriosis)
- Rheumatic (e.g., arthritis)
- Oncological
- Musculoskeletal (e.g., spine, lower extremities)
- Metabolic (e.g., diabetes mellitus).
Measured: 1 minute
PART 1 + 2: General health
The OSTRC questionnaire is used to assess general health before the first study appointment.
The OSTRC contains four key questions recording the level of participation and performance impairment and the degree of symptoms caused by injury or illness. A severity score is then calculated based on these four questions.
Measured: 10 minutes
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted26 Oct 2022
- Study start17 Nov 2022
- Primary completion31 Jan 2025
- Study completion31 Jan 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for GripStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Prospective
- Enrolment
- 520 participants (actual)
Sponsor and investigators
- Lead sponsor
- Johannes Scherr
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Johannes Scherr, Balgrist University Hospital
- Investigators
- Johannes Scherr, Prof Dr med, Principal investigator, Balgrist University Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05594888
- Sponsor's protocol ID
- BASEC-Nr.:2022-01400
- Status last verified
- Feb 2025
- First submitted
- 2 Oct 2022
- Last updated
- 11 Feb 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 11 Feb 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- GRIP: Evaluation of the Comparability of the Maximum Isometric Grip Strength Measurement Assessed With the JAMAR© Hydraulic Hand Dynamometer, the JAMAR© Smart Hand Dynamometer and the Martin Vigorimeter
- ClinicalTrials.gov ID
- NCT05594888
- Acronym / sponsor ID
- BASEC-Nr.:2022-01400
- Conditions
- Grip
- Keywords
- Maximum isometric grip strength, Hand-held dynamometer, Reference values, Physical therapy
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 520 participants (actual)
- Lead sponsor
- Johannes ScherrUniversity, hospital or other
- Study start
- 17 Nov 2022 (actual)
- Primary completion
- 31 Jan 2025 (actual)
- Study completion
- 31 Jan 2025 (actual)
- First posted
- 26 Oct 2022 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Maximum isometric grip strength (MIGS) is a cost-effective, easily accessible, valid and reliable outcome measure for assessing upper body strength in both, adults and children. The the JAMAR Hydraulic Hand Dynamometer is the current gold standard for measuring MIGS. For certain age- and activity-groups, alternative devices may be more appropriate. To date, the quality criteria (test-retest-reliability and validity) of the JAMAR Smart Hand Dynamometer and the Martin Vigorimeter compared to the current gold standard are not yet investigated. Furthermore, no reference values for different age-, sex-, or activity level groups exist with regard to underlying disease entities for these three devices.
Detailed description
This quality analysis of test-retest reliability and validity (PART 1) serves as a basis for a further sensitivity analysis, whereby in a second step, a database with valid personalised age-, sex- and activity-related reference values for the respective measurement instrument, considering chronic concomitant diseases, is to be generated. The objectives of this study are therefore to 1) assess the test-retest reliability (intrasubject and intersession) and validity of JAMAR© Hydraulic and JAMAR© Smart dynamometers and Martin Vigorimeter (PART 1) and 2) undertake a sensitivity analysis providing valid personalised reference values for precision medicine (PART 2).
Thus, no study has yet comprehensively investigated all relevant influencing factors in a single and thus homogeneous study setting, so bias can be expected from this alone. The findings of this two-step study should enable physicians and therapists to compare the grip strength measurements of their patients with normative values in relation to their age, sex and activity group, as well as to any underlying chronic diseases that may be present. This allows realistic treatment and training goals to be set and patient performance to be interpreted.
Study design
- Observational model
- Other
- Time perspective
- Prospective
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| PART 1- Group A | – | –Male and female volunteers (age 18-64 years) working at University Hospital Balgrist. Assessment of validity and intrasubject reliability of maximum isometric grip strength assessed with: * JAMAR© Smart Dynamometer [kg] * JAMAR© Hydraulic Dynamometer [kg] * Martin Vigorimeter [kPa] |
| PART 1 - Group B | – | –Male and female volunteers (age 18-64 years) working at University Hospital Balgrist. Assessment of validity and intrasubject reliability and assessment of intersession reliability of maximum isometric grip strength assessed with: * JAMAR© Smart Dynamometer [kg] * JAMAR© Hydraulic Dynamometer [kg] * Martin Vigorimeter [kPa] |
| PART 2 | – | –Male and female volunteers (age ≥ 10 years). Maximum isometric grip strength is assessed (no intervention): * JAMAR© Smart Dynamometer [kg] * JAMAR© Hydraulic Dynamometer [kg] * Martin Vigorimeter [KPa] |
Who may qualify
- Ages
- 10 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
- Study population
- Part 1: * Male and female volunteers (age 18-64 years) working at University Hospital Balgrist. * 40 participants: to exclude possible sex aspects, ratio ♀: ♂ = 1:1 Part 2: * Male and female volunteers (age ≥ 10 years). MIGS is used as a health indicator throughout different age- and sex groups. * 20 participants per age-group and sex with a total of 520 subjects are planned
Key inclusion criteria (5 listed)
- Male and female volunteers with age 18-64 years
- Body mass index < 30 kg/m2
- Informed consent signed
- Male and female volunteers with age ≥ 10 years
- Informed consent signed (if age < 14 years, signed by parents or legal guardians)
Key exclusion criteria (5 listed)
- Disease or injury (e.g., musculoskeletal or neurological) that could affect upper extremity strength
- Physical impairment of the upper extremity (visible swelling or the presence of a splint or cast)
- Acute pain or infection
- Cognitive impairment (inability to understand and/or follow directions)
- Insufficient language of the German language
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
PART 1: Quality criteria: Intrasubject reliability
Time frame: 5 minutes
Test-retest reliability of the JAMAR© Smart Dynamometer, the JAMAR© Hydraulic Dynamometer and Martin Vigorimeter measuring MIGS will be assessed by intrasubject realiability. --> 5 attempts per device and dominant/adominant hand will be measured.
PART 1: Quality criteria: Intersession reliability
Time frame: 5 minutes
Test-retest reliability of the JAMAR© Smart Dynamometer, the JAMAR© Hydraulic Dynamometer and Martin Vigorimeter measuring MIGS will be assessed by intersession realiability. --> 5 attempts per device and dominant/adominant hand at two different days will be measured.
PART 1: Quality criteria: Validity
Time frame: 5 minutes
Validity of the JAMAR© Smart Dynamometer, the JAMAR© Hydraulic Dynamometer and Martin Vigorimeter measuring MIGS will be assessed by plotting the differences in grip force measurements of the 3 measurement devices against their means, with ± 1.96 SD as cut-off values (limits of agreement). --> 5 attempts per device and dominant/adominant hand will be measured.
PART 2: Comparability of MIGS measurement
Time frame: 10 minutes
Evaluation of comparability of MIGS measurement assessed with the JAMAR© Smart Dynamometer, the JAMAR© Hydraulic Dynamometer and the Martin Vigorimeter -> Best out of 3 attempts per device and dominant/adominant hand
13 secondary outcomes
PART 2: Age-specific refence values - JAMAR© Hydraulic
Time frame: 1 minute
PART 2: Age-specific refence values - JAMAR© Smart
Time frame: 1 minute
PART 2: Age-specific refence values - Martin Vigorimeter
Time frame: 1 minute
PART 2: Sex-specific refence values - JAMAR© Hydraulic
Time frame: 0.5 minute
PART 2: Sex-specific refence values - JAMAR© Smart
Time frame: 0.5 minute
PART 2: Sex-specific refence values - Martin Vigorimeter
Time frame: 0.5 minute
PART 2: Physical activity-specific reference values - JAMAR© Hydraulic
Time frame: 2 minutes
PART 2: Physical activity-specific reference values - JAMAR© Smart
Time frame: 2 minutes
PART 2: Physical activity-specific reference values - Martin Vigorimeter
Time frame: 2 minutes
PART 2: Refence values for subjects with different disease entities - JAMAR© Hydraulic
Time frame: 1 minute
PART 2: Refence values for subjects with different disease entities - JAMAR© Smart
Time frame: 1 minute
PART 2: Refence values for subjects with different disease entities - Martin Vigorimeter.
Time frame: 1 minute
PART 1 + 2: General health
Time frame: 10 minutes
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 11 Feb 2025.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Johannes Scherr, Prof Dr med principal investigator
Balgrist University Hospital
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Grip, run by Johannes Scherr at 1 site in Switzerland.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 11 Feb 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Switzerland. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
PART 1: Quality criteria: Intrasubject reliability (time frame: 5 minutes). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 11 Feb 2025.