Efficacy of Smartphone Application Based Rehabilitations in Patients With Chronic Respiratory or Cardiovascular Disease

Dyspnea symptom is measured according to the Modified Medical Research Council (mMRC) Dyspnea Scale.

The mMRC scale is from 0 to 4:

0: no breathlessness except on strenuous exercise

1. shortness of breath when hurrying on the level or walking up a slight hill
2. walks slower than people of same age on the level because of breathlessness or has to stop to catch breath when walking at their own pace on the level
3. stops for breath after walking ∼100 m or after few minutes on the level
4. too breathless to leave the house, or breathless when dressing or undressing

Dyspnea symptom is measured according to the New York Heart Association Functional Classification (NYHA class).

The NYHA class is from I to IV:

Class I: No limitation of physical activity. Ordinary physical activity does not cause undue fatigue, palpitation (feeling heart beats), or dyspnea (shortness of breath).

Class II(Mild): Slight limitation of physical activity. Comfortable at rest, but ordinary physical activity results in fatigue, palpitation, or dyspnea.

Class III(Moderate): Marked limitation of physical activity. Comfortable at rest, but less than ordinary activity causes fatigue, palpitation, or dyspnea.

Class IV(Severe): Unable to carry out any physical activity without discomfort. Symptoms of cardiac insufficiency at rest. If any physical activity is undertaken, discomfort is increased.

A questionnaire assessing health related quality of life on 5 health dimensions (mobility, self-care, usual activities, pain/discomfort, anxiety/depression). Each item is scored 1-5, yielding a total between 5 and 25.

The scores range from 5 (best performance) to 25 (worst performance).

A questionnaire assessing health related quality of life on 4 health dimensions (physical, mental, social, positive health dimension). Each item is scored 1-4, yielding a total between 8 and 40.

The scores range from 8 (best performance) to 40 (worst performance).

The muscle strength measures hand grip strength. The cut-off value for sarcopenia is < 30 kg

The muscle mass is measured using the Bioelectrical Impedance Analysis. The cut off value for sarcopenia is < 7.26 kg/m^2.

The forced expiratory volume in one second (FEV1) is measured using spirometry. The value will be presented in % predicted value.

The forced vital capacity (FVC) is measured using spirometry. The value will be presented in % predicted value.

The diffusing capacity of the lung for carbon monoxide (DLCO) is measured using single breath holding method.

The value will be presented in % predicted value.

Chest pain symptom is measured according to the Canadian Cardiovascular Society grading of angina pectoris (CCS angina grade).

The CCS angina grade is from I to IV:

Grade I: Angina with strenuous/rapid/prolonged exertion at work or recreation only; no angina with ordinary physical activity, e.g. walking, climbing stairs Grade II: Ordinary activity slightly limited: angina with walking/climbing stairs rapidly, walking uphill, walking or stair climbing after meals, in cold/wind, under emotional stress, during few hours after awakening, walking >2 blocks on level ground, or climbing >1 flight of stairs at normal pace and normal conditions Grade III: Marked limitation of ordinary physical activity: angina with walking 1-2 blocks on level ground or climbing 1 flight of stairs at normal pace and normal conditions Grade IV: Inability to carry on any physical activity without discomfort; anginal syndrome may be present at rest

This test measures total exercise duration.

This test measures metabolic equivalents (METs).