Chronic StrokeNCT05679700

The Effect of Rigid Taping in Chronic Stroke Patients With Knee Hyperextension

A study testing Rigid Taping in people with Chronic Stroke, run by Hacettepe University at 1 site in Turkey (Türkiye).

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Trial summary

In this study, it is aimed to examine the effect of rigid taping on hyperextension control in stroke patients with knee hyperextension in the stance phase of gait. Hypothesis Ho: Rigid taping has no effect on the control of knee hyperextension in stroke patients. Read more about this study

Who is it for?: Ages 18 to 65 years
Conditions the study is for: Chronic Stroke
What is being tested?: Rigid Taping
Could I receive a placebo?: No, everyone receives an active treatment
How many people: 30 participants
Where: 1 siteTurkey (Türkiye)
Study dates: 30 Dec 2022to 15 Nov 2023
Phase: Interventional
Are there results?: None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

Ages 18 to 65 years
All sexes
No healthy volunteers
Adult, Older adult

Who may be able to join

Having had a stroke at least 6 months ago
Ambulation with or without a walking aid (walker, cane or tripod)
To be between 0-3 points according to the Modified Rankin Scoring
Presence of spasticity in any of the lower extremity muscles with a value of at least 1 according to the Modified Ashworth Scale
Getting a score of 24 or higher on the Mini Mental Test
Presence of hyperextension in the stance phase of gait

Who cannot join

Having more than one stroke history
Being diagnosed with dementia
Having a previous diagnosis of orthopedic, psychiatric or other neurological disease
Having a situation that prevents communication
History of surgery or joint contracture involving the lower extremities and gait

Trial locations and contacts

1 site in 1 country.

Turkey (Türkiye)1 site

Hacettepe University
Altındağ, Ankara, 06230

Other trials in Turkey (Türkiye)

About this study

In this study, it is aimed to examine the effect of rigid taping on hyperextension control in stroke patients with knee hyperextension in the stance phase of gait.

Hypothesis Ho: Rigid taping has no effect on the control of knee hyperextension in stroke patients.

H1: Rigid taping has an effect on the control of knee hyperextension in stroke patients.

Conditions: Chronic Stroke
Being tested: Rigid Taping
Keywords: Gait Analysis, Stroke, Knee Hyperextension, Rigid Taping
Medical subject headings: Stroke

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

Rigid TapingOther
Rigid taping was applied to stroke patients with knee hyperextension.

Study groups in NCT05679700
Study group	Role	What they receive
Chronic stroke patients with knee hyperextension	Experimental	Not described Receives: Other: Rigid Taping

What is being measured

The primary outcome is the main question the study is designed to answer.

Vicon Motion Capture System
A total of 16 reflective signs will be placed on certain anatomical points of the participants. Gait analysis will be performed at a distance of 5 meters from the participants. The three-dimensional positions of the reflective marks will be recorded with the 8-camera Vicon motion capture system.
Measured: Baseline
Blade Software System
Data obtained from Vicon motion capture system will be processed with Blade software. With the blade software, kinematic data will be obtained in the computer environment.
Measured: Baseline

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

30 Dec 202215 Nov 2023

First posted11 Jan 2023
Study start30 Dec 2022
Primary completion11 Oct 2023
Study completion15 Nov 2023

Resources

Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
Publications (3)Papers the sponsor has linked to this study.
Other trials for Chronic StrokeStudies of the same condition, open and under way.
More trials run by Hacettepe UniversityThe sponsor's other registered studies.
What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design

Study type: Interventional
Phase: Phase N/A
Primary purpose: Treatment
Allocation: Not applicable
Intervention model: Single group
Masking: None (open label)
Enrolment: 30 participants (actual)

IDs, dates and publications

ClinicalTrials.gov ID: NCT05679700
Sponsor's protocol ID: KA-22045
Status last verified: Jul 2024
First submitted: 21 Dec 2022
Last updated: 8 Jul 2024
Results posted: No
Data monitoring committee: No
FDA-regulated drug: No
FDA-regulated device: No
Individual data sharing: No

Publications

Cooper A, Alghamdi GA, Alghamdi MA, Altowaijri A, Richardson S. The relationship of lower limb muscle strength and knee joint hyperextension during the stance phase of gait in hemiparetic stroke patients. Physiother Res Int. 2012 Sep;17(3):150-6. doi: 10.1002/pri.528. Epub 2011 Dec 7.
PubMed 22147298
Geerars M, Minnaar-van der Feen N, Huisstede BMA. Treatment of knee hyperextension in post-stroke gait. A systematic review. Gait Posture. 2022 Jan;91:137-148. doi: 10.1016/j.gaitpost.2021.08.016. Epub 2021 Aug 24.
PubMed 34695721
Korkusuz S, Korkusuz BS, Ozgoren N, Aritan S, Ceren AN, Topcuoglu MA, Balkan AF. Knee hyperextension in chronic stroke: Associated biomechanical and neuromuscular factors. Clin Biomech (Bristol). 2025 Aug;128:106617. doi: 10.1016/j.clinbiomech.2025.106617. Epub 2025 Jul 17.
PubMed 40706550

Want to know more?

The sponsor has not listed a contact. The official record may have more details.

Talk to your doctor first and take this page with you. Only the study team can confirm whether you can join.

Questions to ask the study team

What is the study trying to find out?
What would I need to do, and how often would I visit?
Could I receive a placebo instead of the treatment?
What are the possible risks and benefits for me?
Will it cost me anything? Are travel or time paid for?
Can I keep seeing my own doctor during the study?
What happens when the study ends?

See locations

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Effect of Anomia Rehabilitation Combined With Metacognitive Training in Patients With Chronic Vascular Aphasia
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A Study of Orforglipron (LY3502970) on Cardiovascular Outcomes in Adults With Atherosclerotic Cardiovascular Disease and/or Chronic Kidney Disease (ATTAIN-Outcomes)
Atherosclerosis Cardiovascular Disease, Chronic Kidney Disease
Not yet recruiting
Proof-of-concept for Use of Transcutaneous Spinal Stimulation (TSS) With the ExaStim® Stimulation System in Adults With Chronic Ischemic Stroke
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Recruiting
Task-Oriented Training Versus High-Intensity Gait Training in People With Chronic Stroke
Stroke, Hemiplegia

All Chronic Stroke trials

Study at a glance

From the registry record, last updated by the sponsor on 8 Jul 2024. Recruitment status is as the sponsor reported it: confirm with the study team.

Official title: The Effect of Rigid Taping in Chronic Stroke Patients With Knee Hyperextension
ClinicalTrials.gov ID: NCT05679700
Acronym / sponsor ID: KA-22045
Conditions: Chronic Stroke
Keywords: Gait Analysis, Stroke, Knee Hyperextension, Rigid Taping
Study type: Interventional
Recruitment status: Completed
Enrolment: 30 participants (actual)
Lead sponsor: Hacettepe UniversityUniversity, hospital or other
Study start: 30 Dec 2022 (actual)
Primary completion: 11 Oct 2023 (actual)
Study completion: 15 Nov 2023 (actual)
First posted: 11 Jan 2023 (actual)
Results: Not posted in the source record

Clinical summary

The research question as the sponsor registered it. This describes what the study plans to test, not what it found.

In this study, it is aimed to examine the effect of rigid taping on hyperextension control in stroke patients with knee hyperextension in the stance phase of gait.

Hypothesis Ho: Rigid taping has no effect on the control of knee hyperextension in stroke patients.

H1: Rigid taping has an effect on the control of knee hyperextension in stroke patients.

Study design

Primary purpose: Treatment
Allocation: Not applicable
Intervention model: Single group
Masking: None (open label)
Number of arms: 1

Arm	Type	Receives
Chronic stroke patients with knee hyperextension	Experimental	Other: Rigid Taping

Who may qualify

Ages: 18 to 65 years
Sex: All
Healthy volunteers: Not accepted
Age groups: Adult, Older adult

Key inclusion criteria (6 listed)

Having had a stroke at least 6 months ago
Ambulation with or without a walking aid (walker, cane or tripod)
To be between 0-3 points according to the Modified Rankin Scoring
Presence of spasticity in any of the lower extremity muscles with a value of at least 1 according to the Modified Ashworth Scale
Getting a score of 24 or higher on the Mini Mental Test

Key exclusion criteria (5 listed)

Having more than one stroke history
Being diagnosed with dementia
Having a previous diagnosis of orthopedic, psychiatric or other neurological disease
Having a situation that prevents communication
History of surgery or joint contracture involving the lower extremities and gait

Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.

Interventions

Intervention	Type	Arms
Rigid TapingRigid taping was applied to stroke patients with knee hyperextension.	Other	Chronic stroke patients with knee hyperextension

Primary outcome

Vicon Motion Capture System
Time frame: Baseline
A total of 16 reflective signs will be placed on certain anatomical points of the participants. Gait analysis will be performed at a distance of 5 meters from the participants. The three-dimensional positions of the reflective marks will be recorded with the 8-camera Vicon motion capture system.
Blade Software System
Time frame: Baseline
Data obtained from Vicon motion capture system will be processed with Blade software. With the blade software, kinematic data will be obtained in the computer environment.

Results and safety

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

Research links

Official record on ClinicalTrials.govLast updated by the sponsor 8 Jul 2024.
Background: PubMed 22147298Cooper A, Alghamdi GA, Alghamdi MA, Altowaijri A, Richardson S. The relationship of lower limb muscle strength and knee joint hyperextension during the stance phase of gait in hemiparetic stroke patients. Physiother Res Int. 2012 Sep;17(3):150-6. doi: 10.1002/pri.528. Epub 2011 Dec 7.
Background: PubMed 34695721Geerars M, Minnaar-van der Feen N, Huisstede BMA. Treatment of knee hyperextension in post-stroke gait. A systematic review. Gait Posture. 2022 Jan;91:137-148. doi: 10.1016/j.gaitpost.2021.08.016. Epub 2021 Aug 24.
Derived from this study: PubMed 40706550Korkusuz S, Korkusuz BS, Ozgoren N, Aritan S, Ceren AN, Topcuoglu MA, Balkan AF. Knee hyperextension in chronic stroke: Associated biomechanical and neuromuscular factors. Clin Biomech (Bristol). 2025 Aug;128:106617. doi: 10.1016/j.clinbiomech.2025.106617. Epub 2025 Jul 17.
Individual participant dataSharing planned: No

Related trials for Chronic Stroke

Recruiting
Effect of Anomia Rehabilitation Combined With Metacognitive Training in Patients With Chronic Vascular Aphasia
Aphasia, Stroke
Recruiting
Hand and Arm Motor Recovery Via Non-invasive Electrical Spinal Cord Stimulation After Stroke
Stroke, Ischemic, Chronic Stroke
RecruitingPhase 3
A Study of Orforglipron (LY3502970) on Cardiovascular Outcomes in Adults With Atherosclerotic Cardiovascular Disease and/or Chronic Kidney Disease (ATTAIN-Outcomes)
Atherosclerosis Cardiovascular Disease, Chronic Kidney Disease
Not yet recruiting
Proof-of-concept for Use of Transcutaneous Spinal Stimulation (TSS) With the ExaStim® Stimulation System in Adults With Chronic Ischemic Stroke
Chronic Stroke, Ischemic Stroke
Recruiting
Task-Oriented Training Versus High-Intensity Gait Training in People With Chronic Stroke
Stroke, Hemiplegia

Referral and contact

AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.

Kadriye Armutlu, Prof. Dr. study chair

Hacettepe University

Süleyman Korkusuz, MSc principal investigator

Hacettepe University

Mehmet Akif Topçuoğlu, Prof. Dr. study chair

Hacettepe University

1 site in 1 country: see every site and its status.

Questions about this trial

What is this clinical trial studying?

A study testing Rigid Taping in people with Chronic Stroke, run by Hacettepe University at 1 site in Turkey (Türkiye).

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 6 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 8 Jul 2024. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Vicon Motion Capture System (time frame: Baseline). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT05679700, which also lists 3 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Jul 2024.