AsthmaNCT05685381
Indoor Air Quality for Black Adults With Uncontrolled Asthma
An observational study of Asthma, run by Columbia University at 2 sites in United States.
Trial summary
The aims of this project are twofold: 1. to characterize indoor air quality components obtained from apartments with gas stoves and open kitchens in a cohort of Black adults with uncontrolled asthma recruited from federally qualified health centers and enrolled in the parent study. 2. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Asthma
- How many people
- 30 participants
- Where
- 2 sitesUnited States
- Study dates
- 19 Jan 2023to 14 Feb 2024
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: Black adults with persistent asthma that receive care at partner federally qualified health centers
Who may be able to join
- Patient participants will
- be adults (> or = 18 years of age)
- self-report race as 'Black' race (African American, African, Caribbean, West Indian, multi-racial [Black AND one or more additional races]); identify their ethnicity as Hispanic OR non-Hispanic
- have clinician-diagnosed persistent asthma (defined as being prescribed inhaled corticosteroids in the last 48 months) or have had an asthma exacerbation (e.g., ER visit, course of Prednisone) regardless of controller medicine use
- receive asthma care at a partner federally qualified health center and
- screen positive for uncontrolled asthma as measured by the Asthma Control Questionnaire- 6 items (ACQ-6) and erroneous beliefs as measured by the Conventional and Alternative Management for Asthma (CAM-A) survey.
Who cannot join
- non-English speaking or
- serious mental health conditions that preclude completion of study procedures or confound analyses
Trial locations and contacts
2 sites in 1 country.
United States2 sites
Sun River Health
Beacon, New York, 12508
Bedford Stuyvesant Family Health Center
Brooklyn, New York, 11216
About this study
Official title: Contextualizing Asthma Self-Management With Measures of Indoor Air Quality for Black Adults With Uncontrolled Asthma
The aims of this project are twofold:
- to characterize indoor air quality components obtained from apartments with gas stoves and open kitchens in a cohort of Black adults with uncontrolled asthma recruited from federally qualified health centers and enrolled in the parent study.
- to conduct a comprehensive assessment of feasibility, implementation, and acceptability of the study.
Read the detailed description
People spend as much as 90% of their time indoors, making indoor air quality (IAQ) particularly important to health. Many homes in New York City, particularly low-income housing, contain gas kitchen appliances, which generate fuel through the combustion of natural gas, generating indoor pollutants. Increasing evidence finds that even low levels of these pollutants are hazardous for human health. Those most vulnerable to ambient air pollution live in homes with gas appliances and inadequate ventilation. Moreover, individuals with pre-existing diseases like asthma are particularly susceptible to adverse health effects from poor IAQ, which gas stoves may exacerbate. This study addresses the important problem of uncontrolled asthma among a group at high risk for asthma and its adverse effects - Black adults who reside in homes with gas stoves and open kitchens. The investigator aims to characterize indoor air quality components in a cohort enrolled in the parent R01 (NCT05341726) and conduct a comprehensive assessment of feasibility including process, implementation and acceptability metrics. Identifying new targets for asthma self-management that could produce better health outcomes, thus addressing an important health inequity issue.
- Conditions
- Asthma
- Keywords
- Asthma, Bronchial Diseases, Respiratory Tract Diseases, Lung Diseases, Obstructive, Lung Diseases, Respiratory Hypersensitivity, Hypersensitivity, Immediate, Hypersensitivity, Immune System Diseases, Greenhouse Effect, Air Pollution, Indoor
- Medical subject headings
- Asthma, Bronchial Diseases, Respiratory Tract Diseases, Lung Diseases, Obstructive, Lung Diseases, Respiratory Hypersensitivity, Hypersensitivity, Immediate, Hypersensitivity
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Black adults with persistent asthma in homes with gas kitchen appliances | Black adults with persistent asthma that reside in homes with kitchen appliances (i.e., cooktops, ovens, and ranges) fueled by combustible gas. | |
| Black adults with persistent asthma in homes without gas kitchen appliances | Black adults with persistent asthma that reside in homes with kitchen appliances (i.e., cooktops, ovens, and ranges) not fueled by combustible gas. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Completion of acceptability questionnaire
The number of participants who complete the acceptability questionnaire. The acceptability questionnaire is a semi-structured interview at the time of indoor air quality sample retrieval and will be guided by the constructs of the Theoretical Framework of Acceptability (e.g., burden, user experience, attitudes, participation intentions).
Measured: Post-trial visit (up to 3 months after intervention completion)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 Jan 2023
- Study start19 Jan 2023
- Primary completion31 Dec 2023
- Study completion14 Feb 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for AsthmaStudies of the same condition, open and under way.
- More trials run by Columbia UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Prospective
- Enrolment
- 30 participants (actual)
Sponsor and investigators
- Lead sponsor
- Columbia University
- Sponsor type
- University, hospital or other
- Collaborators
- National Institute of Nursing Research (NINR)
- Responsible party
- Principal investigator, Maureen George, Columbia University
- Investigators
- Maureen George, PhD, Principal investigator, Columbia University School of Nursing
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05685381
- Sponsor's protocol ID
- AAAT0939 - sub-study
- Other IDs
- 3R01NR019275-02S1
- Status last verified
- Jan 2025
- First submitted
- 5 Jan 2023
- Last updated
- 28 Jan 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
George M, Khurana RK, Bruzzese JM, Zeremski M, DiMango E, Naseem A, Cassells A, Mak E, Benda N, Tobin JN, Chillrud S. Assessing the feasibility of indoor air quality monitoring in low-income housing among Black adults with uncontrolled asthma in New York City. BMC Public Health. 2026 Jul 8. doi: 10.1186/s12889-026-28295-z. Online ahead of print.
PubMed 42420937
Study at a glance
From the registry record, last updated by the sponsor on 28 Jan 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Contextualizing Asthma Self-Management With Measures of Indoor Air Quality for Black Adults With Uncontrolled Asthma
- ClinicalTrials.gov ID
- NCT05685381
- Acronym / sponsor ID
- AAAT0939 - sub-study
- Conditions
- Asthma
- Keywords
- Asthma, Bronchial Diseases, Respiratory Tract Diseases, Lung Diseases, Obstructive, Lung Diseases, Respiratory Hypersensitivity, Hypersensitivity, Immediate, Hypersensitivity
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 30 participants (actual)
- Lead sponsor
- Columbia UniversityUniversity, hospital or other
- Collaborators
- National Institute of Nursing Research (NINR)
- Study start
- 19 Jan 2023 (actual)
- Primary completion
- 31 Dec 2023 (actual)
- Study completion
- 14 Feb 2024 (actual)
- First posted
- 17 Jan 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aims of this project are twofold:
- to characterize indoor air quality components obtained from apartments with gas stoves and open kitchens in a cohort of Black adults with uncontrolled asthma recruited from federally qualified health centers and enrolled in the parent study.
- to conduct a comprehensive assessment of feasibility, implementation, and acceptability of the study.
Detailed description
People spend as much as 90% of their time indoors, making indoor air quality (IAQ) particularly important to health. Many homes in New York City, particularly low-income housing, contain gas kitchen appliances, which generate fuel through the combustion of natural gas, generating indoor pollutants. Increasing evidence finds that even low levels of these pollutants are hazardous for human health. Those most vulnerable to ambient air pollution live in homes with gas appliances and inadequate ventilation. Moreover, individuals with pre-existing diseases like asthma are particularly susceptible to adverse health effects from poor IAQ, which gas stoves may exacerbate. This study addresses the important problem of uncontrolled asthma among a group at high risk for asthma and its adverse effects - Black adults who reside in homes with gas stoves and open kitchens. The investigator aims to characterize indoor air quality components in a cohort enrolled in the parent R01 (NCT05341726) and conduct a comprehensive assessment of feasibility including process, implementation and acceptability metrics. Identifying new targets for asthma self-management that could produce better health outcomes, thus addressing an important health inequity issue.
Study design
- Observational model
- Case-control
- Time perspective
- Prospective
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Black adults with persistent asthma in homes with gas kitchen appliances | – | –Black adults with persistent asthma that reside in homes with kitchen appliances (i.e., cooktops, ovens, and ranges) fueled by combustible gas. |
| Black adults with persistent asthma in homes without gas kitchen appliances | – | –Black adults with persistent asthma that reside in homes with kitchen appliances (i.e., cooktops, ovens, and ranges) not fueled by combustible gas. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- Black adults with persistent asthma that receive care at partner federally qualified health centers
Key inclusion criteria (6 listed)
- Patient participants will
- be adults (> or = 18 years of age)
- self-report race as 'Black' race (African American, African, Caribbean, West Indian, multi-racial [Black AND one or more additional races]); identify their ethnicity as Hispanic OR non-Hispanic
- have clinician-diagnosed persistent asthma (defined as being prescribed inhaled corticosteroids in the last 48 months) or have had an asthma exacerbation (e.g., ER visit, course of Prednisone) regardless of controller medicine use
- receive asthma care at a partner federally qualified health center and
Key exclusion criteria (2 listed)
- non-English speaking or
- serious mental health conditions that preclude completion of study procedures or confound analyses
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Completion of acceptability questionnaire
Time frame: Post-trial visit (up to 3 months after intervention completion)
The number of participants who complete the acceptability questionnaire. The acceptability questionnaire is a semi-structured interview at the time of indoor air quality sample retrieval and will be guided by the constructs of the Theoretical Framework of Acceptability (e.g., burden, user experience, attitudes, participation intentions).
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 28 Jan 2025.
- Derived from this study: PubMed 42420937George M, Khurana RK, Bruzzese JM, Zeremski M, DiMango E, Naseem A, Cassells A, Mak E, Benda N, Tobin JN, Chillrud S. Assessing the feasibility of indoor air quality monitoring in low-income housing among Black adults with uncontrolled asthma in New York City. BMC Public Health. 2026 Jul 8. doi: 10.1186/s12889-026-28295-z. Online ahead of print.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Maureen George, PhD principal investigator
Columbia University School of Nursing
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Asthma, run by Columbia University at 2 sites in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 28 Jan 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Completion of acceptability questionnaire (time frame: Post-trial visit (up to 3 months after intervention completion)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT05685381, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 28 Jan 2025.