Nutritional Status of Chinese Inpatients；Nutritional Service Capacity of Medical Institutions in ChinaCNFD 2020NCT05694104
China Nutrition Fundamental Data 2020
An observational study of Nutritional Status of Chinese Inpatients；Nutritional Service Capacity of Medical Institutions in China, run by Peking Union Medical College Hospital at 1 site in China.
Trial summary
Malnutrition caused by reduced food intake or assimilation and varying degrees of acute or chronic inflammation is a serious and underappreciated risk factor for adverse clinical outcomes. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Nutritional Status of Chinese Inpatients；Nutritional Service Capacity of Medical Institutions in China
- What is being tested?
- Malnutrition
- How many people
- 54,677 participants
- Where
- 1 siteChina
- Study dates
- 24 Aug 2020to 7 Jan 2022
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: A large, nationally representative sample of Chinese adult inpatients
Who may be able to join
- Aged 18 years or older
- Admitted to hospital within 24-48 hours (not emergency) due to tumor or digestive system, respiratory system, cardiovascular system, endocrine system, nervous system, and urinary system disease.
Who cannot join
- With mental illness or memory disorder who were unable to answer questions correctly
- Critically ill patients
- Lack behavioral ability
Trial locations and contacts
1 site in 1 country.
China1 site
Dongcheng district，Peking union medical college hospital
Beijing, Beijing Municipality, 100010
About this study
Malnutrition caused by reduced food intake or assimilation and varying degrees of acute or chronic inflammation is a serious and underappreciated risk factor for adverse clinical outcomes. Despite the substantial health and economic burden, malnutrition remains to affect a considerable proportion of hospitalized patients worldwide. Nationally representative studies from the USA, Australia, and European countries have reported prevalence figures in the range of 8.9% to 80.4%. However, national data in some resource-poor countries, such as China, the largest developing country in the world, are scarce.
We did the China Nutrition Fundamental Data 2020 in a large, nationally representative sample of Chinese adult inpatients to 1) Explore the relationship between nutrition and health; 2) Understand the capacity of nutrition services in Chinese medical institutions.
Read more
This project adopted a multistage, stratified, cluster-sampling procedure based on administrative divisions in China. For each participant, a structured interview was done by trained nutritionists or clinicians. The following data were acquired: weight change within and beyond six months, food intake change within two weeks, nutrition therapy during this hospitalization, and laboratory tests. We also collected information on participants' sociodemographic characteristics and medical history. We took physical measurements, including height, weight, waist circumference, hip circumference, mid-arm circumference, calf circumference, handgrip strength, and blood pressure following standard protocols. Body composition was measured using bioimpedance analysis (BIA). In total, 54677 inpatients from 291 project hospitals completed information collection.
In addition, we collected information on the number of beds, the nutrition support team, the nutrition treatment plan and the construction of a full-time nutrition physician or nutrition nurse, the routine monitoring methods, interventions, and distribution of brochures for patients with malnutrition or nutritional risk in each project hospital and 37 other hospitals based on the principle of voluntary participation. A total of 328 hospitals completed information collection.
This project will establish standards for nutrition risk assessment, diagnosis, and treatment of inpatients in China, promote the construction of clinical nutrition departments, and improve the nutritional status of inpatients.
- Being tested
- Malnutrition
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
MalnutritionOther
For the diagnosis of malnutrition, we adopted the Global Leadership Initiative on Malnutrition (GLIM) scheme based on three phenotypic criteria (non-volitional weight loss, low body mass index, and reduced muscle mass) and two etiologic criteria (reduced food intake or assimilation, and inflammation or disease burden). To diagnose malnutrition at least one phenotypic criterion and one etiologic criterion should be present in patients with nutritional risk.
What is being measured
The primary outcome is the main question the study is designed to answer.
Number of participants diagnosed with malnutrition
For the diagnosis of malnutrition, we adopted the Global Leadership Initiative on Malnutrition (GLIM) scheme based on three phenotypic criteria (non-volitional weight loss, low body mass index, and reduced muscle mass) and two etiologic criteria (reduced food intake or assimilation, and inflammation or disease burden). To diagnose malnutrition at least one phenotypic criterion and one etiologic criterion should be present in patients with nutritional risk.
Measured: The 1 day of the survey
Prevalence of nutritional risk
Nutritional risk was defined as Nutritional Risk Screening 2002 (NRS2002) score≥3.
Measured: The 1 day of the survey
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted23 Jan 2023
- Study start24 Aug 2020
- Primary completion2 Aug 2021
- Study completion7 Jan 2022
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Nutritional Status of Chinese Inpatients；Nutritional Service Capacity of Medical Institutions in ChinaStudies of the same condition, open and under way.
- More trials run by Peking Union Medical College HospitalThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Ecologic or community
- Time perspective
- Cross-sectional
- Enrolment
- 54,677 participants (actual)
Sponsor and investigators
- Lead sponsor
- Peking Union Medical College Hospital
- Sponsor type
- University, hospital or other
- Collaborators
- National Institute of Hospital Administration, National Health Commission
- Responsible party
- Principal investigator, Wei Chen, Peking Union Medical College Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05694104
- Sponsor's protocol ID
- ZS-2614
- Acronym
- CNFD 2020
- Status last verified
- Jan 2023
- First submitted
- 12 Jan 2023
- Last updated
- 23 Jan 2023
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Publications
Deng LM, Liu SP, Long JF, Mo H, Liu M, Liu JY, Zhang YL, Xu DF, Yu HZ, Chen L, Cai H, Yang SB, Xiang M, Liu M, Sun Y, Xie ZJ, Zeng MM, Xie GX. Prevalence of malnutrition and appropriateness of nutritional support in hospitalized patients: a GLIM-based study. Front Nutr. 2025 Oct 10;12:1667821. doi: 10.3389/fnut.2025.1667821. eCollection 2025.
PubMed 41141257
Study at a glance
From the registry record, last updated by the sponsor on 23 Jan 2023. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- China Nutrition Fundamental Data 2020
- ClinicalTrials.gov ID
- NCT05694104
- Acronym / sponsor ID
- CNFD 2020 / ZS-2614
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 54,677 participants (actual)
- Lead sponsor
- Peking Union Medical College HospitalUniversity, hospital or other
- Collaborators
- National Institute of Hospital Administration, National Health Commission
- Study start
- 24 Aug 2020 (actual)
- Primary completion
- 2 Aug 2021 (actual)
- Study completion
- 7 Jan 2022 (actual)
- First posted
- 23 Jan 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Malnutrition caused by reduced food intake or assimilation and varying degrees of acute or chronic inflammation is a serious and underappreciated risk factor for adverse clinical outcomes. Despite the substantial health and economic burden, malnutrition remains to affect a considerable proportion of hospitalized patients worldwide. Nationally representative studies from the USA, Australia, and European countries have reported prevalence figures in the range of 8.9% to 80.4%. However, national data in some resource-poor countries, such as China, the largest developing country in the world, are scarce.
We did the China Nutrition Fundamental Data 2020 in a large, nationally representative sample of Chinese adult inpatients to 1) Explore the relationship between nutrition and health; 2) Understand the capacity of nutrition services in Chinese medical institutions.
This project adopted a multistage, stratified, cluster-sampling procedure based on administrative divisions in China. For each participant, a structured interview was done by trained nutritionists or clinicians. The following data were acquired: weight change within and beyond six months, food intake change within two weeks, nutrition therapy during this hospitalization, and laboratory tests. We also collected information on participants' sociodemographic characteristics and medical history. We took physical measurements, including height, weight, waist circumference, hip circumference, mid-arm circumference, calf circumference, handgrip strength, and blood pressure following standard protocols. Body composition was measured using bioimpedance analysis (BIA). In total, 54677 inpatients from 291 project hospitals completed information collection.
In addition, we collected information on the number of beds, the nutrition support team, the nutrition treatment plan and the construction of a full-time nutrition physician or nutrition nurse, the routine monitoring methods, interventions, and distribution of brochures for patients with malnutrition or nutritional risk in each project hospital and 37 other hospitals based on the principle of voluntary participation. A total of 328 hospitals completed information collection.
This project will establish standards for nutrition risk assessment, diagnosis, and treatment of inpatients in China, promote the construction of clinical nutrition departments, and improve the nutritional status of inpatients.
Study design
- Observational model
- Ecologic or community
- Time perspective
- Cross-sectional
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- A large, nationally representative sample of Chinese adult inpatients
Key inclusion criteria (2 listed)
- Aged 18 years or older
- Admitted to hospital within 24-48 hours (not emergency) due to tumor or digestive system, respiratory system, cardiovascular system, endocrine system, nervous system, and urinary system disease.
Key exclusion criteria (3 listed)
- With mental illness or memory disorder who were unable to answer questions correctly
- Critically ill patients
- Lack behavioral ability
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| MalnutritionFor the diagnosis of malnutrition, we adopted the Global Leadership Initiative on Malnutrition (GLIM) scheme based on three phenotypic criteria (non-volitional weight loss, low body mass index, and reduced muscle mass) and two etiologic criteria (reduced food intake or assimilation, and inflammation or disease burden). To diagnose malnutrition at least one phenotypic criterion and one etiologic criterion should be present in patients with nutritional risk. | Other | – |
Primary outcome
Number of participants diagnosed with malnutrition
Time frame: The 1 day of the survey
For the diagnosis of malnutrition, we adopted the Global Leadership Initiative on Malnutrition (GLIM) scheme based on three phenotypic criteria (non-volitional weight loss, low body mass index, and reduced muscle mass) and two etiologic criteria (reduced food intake or assimilation, and inflammation or disease burden). To diagnose malnutrition at least one phenotypic criterion and one etiologic criterion should be present in patients with nutritional risk.
Prevalence of nutritional risk
Time frame: The 1 day of the survey
Nutritional risk was defined as Nutritional Risk Screening 2002 (NRS2002) score≥3.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 23 Jan 2023.
- Derived from this study: PubMed 41141257Deng LM, Liu SP, Long JF, Mo H, Liu M, Liu JY, Zhang YL, Xu DF, Yu HZ, Chen L, Cai H, Yang SB, Xiang M, Liu M, Sun Y, Xie ZJ, Zeng MM, Xie GX. Prevalence of malnutrition and appropriateness of nutritional support in hospitalized patients: a GLIM-based study. Front Nutr. 2025 Oct 10;12:1667821. doi: 10.3389/fnut.2025.1667821. eCollection 2025.
- Individual participant dataSharing planned: Undecided
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Nutritional Status of Chinese Inpatients；Nutritional Service Capacity of Medical Institutions in China, run by Peking Union Medical College Hospital at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 23 Jan 2023. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Number of participants diagnosed with malnutrition (time frame: The 1 day of the survey). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT05694104, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 Jan 2023.