Patellofemoral Pain SyndromeNCT05707039
Comparison of Open and Closed Chain Exercises in Athletes With Patellofemoral Pain Syndrome
A study testing Open kinetic chain exercises and Closed kinetic chain exercises in people with Patellofemoral Pain Syndrome, run by Riphah International University at 1 site in Pakistan.
Trial summary
Patellofemoral pain syndrome (PFPS) is a common source of knee pain in the physically active population, predominantly in women. The incidence rate of PFPS among athletes is 25 percent, which is higher than that of general population. Read more about this study
- Who is it for?
- Ages 18 to 30 years
- Conditions the study is for
- Patellofemoral Pain Syndrome
- What is being tested?
- Open kinetic chain exercises and Closed kinetic chain exercises
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 24 participants
- Where
- 1 sitePakistan
- Study dates
- 1 Feb 2022to Feb 2023
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 30 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Adult athletes with age 18 to 30 years
- Anterior Knee pain
- An insidious onset of symptoms not related to trauma.
- Pain with compression of patella.
- Pain on palpation of patellar facets.
- Experienced players (who are in practice from last 8 months or a year).
Who cannot join
- Symptoms present less than 1 month.
- Intra-articular knee pathologies like O.A, R.A etc
- History of knee surgery within last year.
- History of traumatic injuries like patellar dislocations or subluxation
- Any other lower extremity injuries.
Trial locations and contacts
1 site in 1 country.
Pakistan1 site, 1 recruiting
- Recruiting
Pakistan Sports Board
Lahore, Punjab Province, 5433
Muhammad Asrar Yousaf, mphil, 030040995505, asrar.yousaf@riphah.edu.pk
Rutab Nasir, MS-SPT
About this study
Official title: Comparison of Open and Closed Chain Exercises on Pain Function and Balance in Athletes With Patellofemoral Pain Syndrome
Patellofemoral pain syndrome (PFPS) is a common source of knee pain in the physically active population, predominantly in women. The incidence rate of PFPS among athletes is 25 percent, which is higher than that of general population. PFPS is caused by repetitive stress and aggravated in athletes by cycling and running. These symptoms are caused by structural or biomechanical changes of the joint, which becomes exacerbated by activities such as going up and down stairs, sit for a prolonged period, squatting or kneeling, resulting in increased compressive forces in the joint patellofemoral. It is characterized by defused pain in front of knee. Other signs also present are the patellar crepitus, swelling, and joint blockage despite being deemed a multifactorial condition with no single cure, PFPS is commonly attributed to muscular dysfunction, for which conservative rehabilitation is the treatment of choice. Historically, PFPS has been linked to impairments of the quadriceps muscle.
Read the detailed description
This study will be a randomized clinical trial will be conducted in Pakistan sports board Lahore, Model town Sports Club Lahore and Sheikh Zaid Hospital, Lahore. Sample size will be taken to evaluate the effects of open chain exercise and closed chain exercise among athletes with an age group of 18 - 40 years. Non probability convenient sampling technique would be used. Players having an experience of at least 8 months would be a part of study experiencing recurrent knee pain. Participants will be randomly assigned to 2 groups. Group A will include participants who will receive open kinetic chain exercises 3sets of 10 repetitions for each exercise along with the general training. Group B will include the participants who will receive closed kinetic chain exercises 3sets of 10 repetitions for each exercise along with general training.3sessions per week will be given for 6weeks.The subjects will be assessed for pain, function and balance at baseline and after 6weeks of treatment. After collecting data from defined settingit will be entered and analyzed using statistical package for social sciences (SPSS) for Windows software, version 25.
- Conditions
- Patellofemoral Pain Syndrome
- Being tested
- Open kinetic chain exercises, Closed kinetic chain exercises
- Keywords
- PFPS, OCKE, CCKE
- Medical subject headings
- Patellofemoral Pain Syndrome
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Open kinetic chain exercisesOther
In open chain exercises extremities are free to move and there is no weight bearing.
Closed kinetic chain exercisesOther
In closed kinetic chain exercises extremities are fixed and weight bearing is done.
| Study group | Role | What they receive |
|---|---|---|
| Open chain kinetic exercises | Experimental | In open chain exercises extremities are free to move and there is no weight bearing. Subjects performed group of exercises, 3sets of 10 repetitions for each exercise after warm-up and stretching exercises The open kinetic chain exercise program consisted of 1) maximal static quadriceps muscle contractions Receives: Other: Open kinetic chain exercises |
| Closed Chain Kinetic Exercises | Experimental | In closed kinetic chain exercises extremities are fixed and weight bearing is done. Subjects performed group of exercises, 3sets with 10 repetitions for each exercise after warm up and stretching exercises. The closed kinetic chain exercise program consisted of 1) seated leg presses, 2) one-third knee bends on one leg and on both legs, 3) stationary bicycling, 4) rowing-machine exercises, 5) step-up and step-down exercises. Each exercise in the closed kinetic chain protocol was performed dynamically with a 3-second rest between repetitions. Receives: Other: Closed kinetic chain exercises |
What is being measured
The primary outcome is the main question the study is designed to answer.
NPRS
Numerical Pain Rating Scale (NPRS) is a subjective measure in which individuals rate their pain on an eleven-point numerical scale.
Measured: 6 weeks
LEFS
Lower Extremity Functional Scale (LEFS) is to measure "patients' initial function, ongoing progress, and outcome" for a wide range of lower-extremity conditions.
Measured: 6 week
Y balance test
Y Balance test is a dynamic test required for proprioception along with strength and flexibility.
Measured: 6 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted31 Jan 2023
- Study start1 Feb 2022
- Primary completionFeb 2023 (estimated)
- Study completionFeb 2023 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Patellofemoral Pain SyndromeStudies of the same condition, open and under way.
- More trials run by Riphah International UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 24 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Muhammad Asrar Yousaf, mphil, Principal investigator, Riphah International University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05707039
- Sponsor's protocol ID
- REC/RCR&AHS/22/0406
- Status last verified
- Jan 2023
- First submitted
- 22 Jan 2023
- Last updated
- 31 Jan 2023
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 31 Jan 2023. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of Open and Closed Chain Exercises on Pain Function and Balance in Athletes With Patellofemoral Pain Syndrome
- ClinicalTrials.gov ID
- NCT05707039
- Acronym / sponsor ID
- REC/RCR&AHS/22/0406
- Conditions
- Patellofemoral Pain Syndrome
- Keywords
- PFPS, OCKE, CCKE
- Study type
- Interventional
- Recruitment status
- Unknown status
- Enrolment
- 24 participants (estimated)
- Lead sponsor
- Riphah International UniversityUniversity, hospital or other
- Study start
- 1 Feb 2022 (actual)
- Primary completion
- Feb 2023 (estimated)
- Study completion
- Feb 2023 (estimated)
- First posted
- 31 Jan 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Patellofemoral pain syndrome (PFPS) is a common source of knee pain in the physically active population, predominantly in women. The incidence rate of PFPS among athletes is 25 percent, which is higher than that of general population. PFPS is caused by repetitive stress and aggravated in athletes by cycling and running. These symptoms are caused by structural or biomechanical changes of the joint, which becomes exacerbated by activities such as going up and down stairs, sit for a prolonged period, squatting or kneeling, resulting in increased compressive forces in the joint patellofemoral. It is characterized by defused pain in front of knee. Other signs also present are the patellar crepitus, swelling, and joint blockage despite being deemed a multifactorial condition with no single cure, PFPS is commonly attributed to muscular dysfunction, for which conservative rehabilitation is the treatment of choice. Historically, PFPS has been linked to impairments of the quadriceps muscle.
Detailed description
This study will be a randomized clinical trial will be conducted in Pakistan sports board Lahore, Model town Sports Club Lahore and Sheikh Zaid Hospital, Lahore. Sample size will be taken to evaluate the effects of open chain exercise and closed chain exercise among athletes with an age group of 18 - 40 years. Non probability convenient sampling technique would be used. Players having an experience of at least 8 months would be a part of study experiencing recurrent knee pain. Participants will be randomly assigned to 2 groups. Group A will include participants who will receive open kinetic chain exercises 3sets of 10 repetitions for each exercise along with the general training. Group B will include the participants who will receive closed kinetic chain exercises 3sets of 10 repetitions for each exercise along with general training.3sessions per week will be given for 6weeks.The subjects will be assessed for pain, function and balance at baseline and after 6weeks of treatment. After collecting data from defined settingit will be entered and analyzed using statistical package for social sciences (SPSS) for Windows software, version 25.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Open chain kinetic exercises | Experimental | Other: Open kinetic chain exercisesIn open chain exercises extremities are free to move and there is no weight bearing. Subjects performed group of exercises, 3sets of 10 repetitions for each exercise after warm-up and stretching exercises The open kinetic chain exercise program consisted of 1) maximal static quadriceps muscle contractions |
| Closed Chain Kinetic Exercises | Experimental | Other: Closed kinetic chain exercisesIn closed kinetic chain exercises extremities are fixed and weight bearing is done. Subjects performed group of exercises, 3sets with 10 repetitions for each exercise after warm up and stretching exercises. The closed kinetic chain exercise program consisted of 1) seated leg presses, 2) one-third knee bends on one leg and on both legs, 3) stationary bicycling, 4) rowing-machine exercises, 5) step-up and step-down exercises. Each exercise in the closed kinetic chain protocol was performed dynamically with a 3-second rest between repetitions. |
Who may qualify
- Ages
- 18 to 30 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (6 listed)
- Adult athletes with age 18 to 30 years
- Anterior Knee pain
- An insidious onset of symptoms not related to trauma.
- Pain with compression of patella.
- Pain on palpation of patellar facets.
Key exclusion criteria (5 listed)
- Symptoms present less than 1 month.
- Intra-articular knee pathologies like O.A, R.A etc
- History of knee surgery within last year.
- History of traumatic injuries like patellar dislocations or subluxation
- Any other lower extremity injuries.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Open kinetic chain exercisesIn open chain exercises extremities are free to move and there is no weight bearing. | Other | Open chain kinetic exercises |
| Closed kinetic chain exercisesIn closed kinetic chain exercises extremities are fixed and weight bearing is done. | Other | Closed Chain Kinetic Exercises |
Primary outcome
NPRS
Time frame: 6 weeks
Numerical Pain Rating Scale (NPRS) is a subjective measure in which individuals rate their pain on an eleven-point numerical scale.
LEFS
Time frame: 6 week
Lower Extremity Functional Scale (LEFS) is to measure "patients' initial function, ongoing progress, and outcome" for a wide range of lower-extremity conditions.
Y balance test
Time frame: 6 weeks
Y Balance test is a dynamic test required for proprioception along with strength and flexibility.
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 31 Jan 2023.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Muhammad Asrar Yousaf, mphil principal investigator
Riphah International University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Open kinetic chain exercises and Closed kinetic chain exercises in people with Patellofemoral Pain Syndrome, run by Riphah International University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 31 Jan 2023. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
Contact Imran Amjad, Phd (03324390125, imran.amjad@riphah.edu.pk), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
NPRS (time frame: 6 weeks). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 31 Jan 2023.