Patellofemoral Pain SyndromeNCT05708495
Ilium Mobilization in Patellofemoral Pain Syndrome Treatment
A study testing posterior ilium mobilization and strengthening and stretching exercises in people with Patellofemoral Pain Syndrome, run by Cairo University at 1 site in Egypt.
Trial summary
Aim of the study is to investigate the effect of adding posterior ilium mobilization on knee pain, knee function, anterior pelvic tilt, dynamic knee valgus, muscle strength of extensors, abductors and external rotators of hip and knee extensors in patients with patellofemoral pain syndrome. Read more about this study
- Who is it for?
- Ages 18 to 35 years
- Conditions the study is for
- Patellofemoral Pain Syndrome
- What is being tested?
- posterior ilium mobilization and strengthening and stretching exercises
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 36 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Jun 2023to 1 May 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 35 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Age of the subjects between 18-35 years.
- BMI will be ≤ 29.5
- Anterior or retro patellar knee pain for at least 6 weeks duration.
- Foot posture index score from +6 to +12.
- Anterior pelvic tilt angle more than 8 degree.
- Pain elicited at least by two of the following four tests; (i) Isometric muscle contraction with slight bent knee,(ii) palpation of the patellofemoral joint line, (iii) patellar compression against the femoral bone (iv) active resisted knee extension.
- Pain intensity more than 3 at ANPS and provoked by at least two of the following activities: running, walking, hopping, squatting, stair negotiation, kneeling, or prolonged sitting.
Who cannot join
- Meniscal or other intraarticular pathologic conditions; cruciate or collateral ligament involvement.
- A history of traumatic patellar subluxation or dislocation.
- Previous surgery in the knee, ankle and hip joints.
- Knee, ankle and hip joints osteoarthritis.
- Taking non-steroidal anti-inflammatory drugs or corticosteroids within 24 h before the test.
- History of brain injury or vestibular disorder within the last 6 months.
- Pregnant female.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Efficacy of Adding Posterior Ilium Mobilization With Movement to Treatment of Patellofemoral Pain Syndrome
Aim of the study is to investigate the effect of adding posterior ilium mobilization on knee pain, knee function, anterior pelvic tilt, dynamic knee valgus, muscle strength of extensors, abductors and external rotators of hip and knee extensors in patients with patellofemoral pain syndrome.
- Conditions
- Patellofemoral Pain Syndrome
- Being tested
- posterior ilium mobilization, strengthening and stretching exercises
- Keywords
- patellofemoral pain syndrome, strength, stretch, mobilization, ilium, innominate
- Medical subject headings
- Patellofemoral Pain Syndrome
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
posterior ilium mobilizationOther
the therapist will mobilize the innominate on the affected side posteriorly
strengthening and stretching exercisesOther
the participants will receive strengthening exercises on the hip and knee joint beside that they will receive stretching exercises
| Study group | Role | What they receive |
|---|---|---|
| Control group | Active comparator | Not described Receives: Other: strengthening and stretching exercises |
| Study group | Experimental | Not described Receives: Other: posterior ilium mobilization; Other: strengthening and stretching exercises |
What is being measured
The primary outcome is the main question the study is designed to answer.
Changes in pain
Arabic Numeric pain rating scale will be used to assess pain changes during walking, hopping, squatting, stair negotiation, kneeling, or prolonged sitting.
This scale measures pain severity on a scale of 0 to 10 points, with 0 representing no pain and 10 signifying the most severe pain possible.
Measured: It will be assessed at baseline and after 4 weeks
Changes in knee functional disability
The Arabic version of Anterior knee pain scale will be used to assess the knee functional disability.
It is a self-administered, weighted questionnaire that analyzes 13 items, including pain and function, with a maximum score of 100 points and minimum score of 0 points. Higher scores indicate greater lower extremity function. It documents responses to six activities linked with anterior knee pain (walking, running, jumping, climbing stairs, squatting, and sitting for prolonged periods with knee bent).
Measured: It will be assessed at baseline and after 4 weeks
Secondary outcomes (6)
Changes in hip abductors strength
Handheld dynamometer will be used to assess changes in muscle strength
Measured: It will be assessed at baseline and after 4 weeks
Changes in hip extensors strength
Handheld dynamometer will be used to assess changes in muscle strength
Measured: It will be assessed at baseline and after 4 weeks
Changes in hip external rotators strength
Handheld dynamometer will be used to assess changes in muscle strength
Measured: It will be assessed at baseline and after 4 weeks
Changes in knee extensors strength
Handheld dynamometer will be used to assess changes in muscle strength
Measured: It will be assessed at baseline and after 4 weeks
Changes in dynamic knee valgus
Cell phone Camera, tripod device and Kinovea Computer Program (KCP) will be used to assess knee frontal plane projection angle to detect changes in knee valgus during step down test
Measured: It will be assessed at baseline and after 4 weeks
Changes in pelvic tilt angle
Palpation Meter (PALM) will be used to assess changes in pelvic tilt angle
Measured: It will be assessed at baseline and after 4 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted1 Feb 2023
- Study start1 Jun 2023
- Primary completion1 May 2024
- Study completion1 May 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Patellofemoral Pain SyndromeStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind
- Who is masked
- Participant, Investigator, Outcomes assessor
- Enrolment
- 36 participants (actual)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Labib Mousa Labib Ghali, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05708495
- Sponsor's protocol ID
- Ilium mobilization
- Status last verified
- Sep 2024
- First submitted
- 23 Jan 2023
- Last updated
- 30 May 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 30 May 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Efficacy of Adding Posterior Ilium Mobilization With Movement to Treatment of Patellofemoral Pain Syndrome
- ClinicalTrials.gov ID
- NCT05708495
- Acronym / sponsor ID
- Ilium mobilization
- Conditions
- Patellofemoral Pain Syndrome
- Keywords
- patellofemoral pain syndrome, strength, stretch, mobilization, ilium, innominate
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 36 participants (actual)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 1 Jun 2023 (actual)
- Primary completion
- 1 May 2024 (actual)
- Study completion
- 1 May 2024 (actual)
- First posted
- 1 Feb 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Aim of the study is to investigate the effect of adding posterior ilium mobilization on knee pain, knee function, anterior pelvic tilt, dynamic knee valgus, muscle strength of extensors, abductors and external rotators of hip and knee extensors in patients with patellofemoral pain syndrome.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind (participant, investigator, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Control group | Active comparator | Other: strengthening and stretching exercises |
| Study group | Experimental | Other: posterior ilium mobilization, Other: strengthening and stretching exercises |
Who may qualify
- Ages
- 18 to 35 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (7 listed)
- Age of the subjects between 18-35 years.
- BMI will be ≤ 29.5
- Anterior or retro patellar knee pain for at least 6 weeks duration.
- Foot posture index score from +6 to +12.
- Anterior pelvic tilt angle more than 8 degree.
Key exclusion criteria (7 listed)
- Meniscal or other intraarticular pathologic conditions; cruciate or collateral ligament involvement.
- A history of traumatic patellar subluxation or dislocation.
- Previous surgery in the knee, ankle and hip joints.
- Knee, ankle and hip joints osteoarthritis.
- Taking non-steroidal anti-inflammatory drugs or corticosteroids within 24 h before the test.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| posterior ilium mobilizationthe therapist will mobilize the innominate on the affected side posteriorly | Other | Study group |
| strengthening and stretching exercisesthe participants will receive strengthening exercises on the hip and knee joint beside that they will receive stretching exercises | Other | Control group, Study group |
Primary outcome
Changes in pain
Time frame: It will be assessed at baseline and after 4 weeks
Arabic Numeric pain rating scale will be used to assess pain changes during walking, hopping, squatting, stair negotiation, kneeling, or prolonged sitting. This scale measures pain severity on a scale of 0 to 10 points, with 0 representing no pain and 10 signifying the most severe pain possible.
Changes in knee functional disability
Time frame: It will be assessed at baseline and after 4 weeks
The Arabic version of Anterior knee pain scale will be used to assess the knee functional disability. It is a self-administered, weighted questionnaire that analyzes 13 items, including pain and function, with a maximum score of 100 points and minimum score of 0 points. Higher scores indicate greater lower extremity function. It documents responses to six activities linked with anterior knee pain (walking, running, jumping, climbing stairs, squatting, and sitting for prolonged periods with knee bent).
6 secondary outcomes
Changes in hip abductors strength
Time frame: It will be assessed at baseline and after 4 weeks
Changes in hip extensors strength
Time frame: It will be assessed at baseline and after 4 weeks
Changes in hip external rotators strength
Time frame: It will be assessed at baseline and after 4 weeks
Changes in knee extensors strength
Time frame: It will be assessed at baseline and after 4 weeks
Changes in dynamic knee valgus
Time frame: It will be assessed at baseline and after 4 weeks
Changes in pelvic tilt angle
Time frame: It will be assessed at baseline and after 4 weeks
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 30 May 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing posterior ilium mobilization and strengthening and stretching exercises in people with Patellofemoral Pain Syndrome, run by Cairo University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 30 May 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Changes in pain (time frame: It will be assessed at baseline and after 4 weeks). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 30 May 2025.