Temporomandibular Joint DisordersEMDJWNCT05710952
Impact of Orthodontic Treatment on the Temporomandibular Joints (TMJ) Assessed by Modjaw
A study testing Review by Modjaw in people with Temporomandibular Joint Disorders, run by University Hospital, Montpellier at 1 site in France.
Trial summary
The aim of the study is to assess the correlation between orthodontic treatment and temporomandibular joint (TMJ). For that, an evaluation with a virtual articulator (Modjaw) is carried out before and after the treatment. The condylar course are compared. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Temporomandibular Joint Disorders
- What is being tested?
- Review by Modjaw
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 32 participants
- Where
- 1 siteFrance
- Study dates
- 7 Feb 2023to 28 Sep 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Major patient (≥18 years)
- First dentofacial orthopedic consultation at the dental clinic of Montpellier
- Patient requiring multi-attachment orthodontic treatment (vestibular or lingual) for a duration ≤2 years
- Signed informed consent
Who cannot join
- Syndromic patient
- Orthodontic treatment with aligners
- General joint or bone pathology
- Patients with oral hygiene incompatible with orthodontic treatment
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Impact of Orthodontic Treatment on the Temporomandibular Joints (TMJ) Assessed by Modjaw in Adults
The aim of the study is to assess the correlation between orthodontic treatment and temporomandibular joint (TMJ). For that, an evaluation with a virtual articulator (Modjaw) is carried out before and after the treatment. The condylar course are compared. Furthermore, the eventual TMJ symptoms are also compared before and after.
- Conditions
- Temporomandibular Joint Disorders
- Being tested
- Review by Modjaw
- Keywords
- Temporomandibular joint, Orthodontic, Modjaw, Orthodontic braces
- Medical subject headings
- Temporomandibular Joint Disorders
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Review by ModjawDevice
A review by Modjaw's will be done before the braces treatment and after.
| Study group | Role | What they receive |
|---|---|---|
| Braces | Other | Patients will receive an orthodontic treatment with fixed braces for 12 to 24 months Receives: Device: Review by Modjaw |
What is being measured
The primary outcome is the main question the study is designed to answer.
Gap reduction between the interincisive point in mouth opening and the ordinate axis
Define if there is an improvement in the straightness of the condylar path by measuring the gap between the interincisive point in mouth opening and the ordinate axis in mm assessed by Modjaw
Measured: Up to 24 months
Secondary outcomes (7)
Condylar courses homogeneity
Qualitative comparison of the homogeneity of the condylar courses before and after treatment
Measured: Up to 24 months
Condylar courses symmetry
Qualitative comparison of the symmetry of the condylar symmetry before and after treatment
Measured: Up to 24 months
Condylar courses straightness
Qualitative comparison of the straightness of the condylar symmetry before and after treatment
Measured: Up to 24 months
Amplitude of the condylar path
Virtual path length in mm assessed by Modjaw
Measured: Up to 24 months
Straightness of the condylar path
Y-axis deviation in mm assessed by Modjaw
Measured: Up to 24 months
Adverses events
Adverse events will be assessed before and after treatment
Measured: Up to 24 months
Pain assessment
Pain is assessed by an analogic visual scale from 0 (no pain) to 10 (maximum pain)
Measured: Up to 24 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted2 Feb 2023
- Study start7 Feb 2023
- Primary completion28 Sep 2026
- Study completion28 Sep 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Temporomandibular Joint DisordersStudies of the same condition, open and under way.
- More trials run by University Hospital, MontpellierThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Diagnosis
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 32 participants (actual)
Sponsor and investigators
- Lead sponsor
- University Hospital, Montpellier
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05710952
- Sponsor's protocol ID
- RECHMPL22_0509
- Acronym
- EMDJW
- Status last verified
- Oct 2026
- First submitted
- 12 Jan 2023
- Last updated
- 2 Nov 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 2 Nov 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Impact of Orthodontic Treatment on the Temporomandibular Joints (TMJ) Assessed by Modjaw in Adults
- ClinicalTrials.gov ID
- NCT05710952
- Acronym / sponsor ID
- EMDJW / RECHMPL22_0509
- Conditions
- Temporomandibular Joint Disorders
- Keywords
- Temporomandibular joint, Orthodontic, Modjaw, Orthodontic braces
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 32 participants (actual)
- Lead sponsor
- University Hospital, MontpellierUniversity, hospital or other
- Study start
- 7 Feb 2023 (actual)
- Primary completion
- 28 Sep 2026 (actual)
- Study completion
- 28 Sep 2026 (actual)
- First posted
- 2 Feb 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of the study is to assess the correlation between orthodontic treatment and temporomandibular joint (TMJ). For that, an evaluation with a virtual articulator (Modjaw) is carried out before and after the treatment. The condylar course are compared. Furthermore, the eventual TMJ symptoms are also compared before and after.
Study design
- Primary purpose
- Diagnosis
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Braces | Other | Device: Review by ModjawPatients will receive an orthodontic treatment with fixed braces for 12 to 24 months |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Major patient (≥18 years)
- First dentofacial orthopedic consultation at the dental clinic of Montpellier
- Patient requiring multi-attachment orthodontic treatment (vestibular or lingual) for a duration ≤2 years
- Signed informed consent
Key exclusion criteria (4 listed)
- Syndromic patient
- Orthodontic treatment with aligners
- General joint or bone pathology
- Patients with oral hygiene incompatible with orthodontic treatment
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Review by ModjawA review by Modjaw's will be done before the braces treatment and after. | Device | Braces |
Primary outcome
Gap reduction between the interincisive point in mouth opening and the ordinate axis
Time frame: Up to 24 months
Define if there is an improvement in the straightness of the condylar path by measuring the gap between the interincisive point in mouth opening and the ordinate axis in mm assessed by Modjaw
7 secondary outcomes
Condylar courses homogeneity
Time frame: Up to 24 months
Condylar courses symmetry
Time frame: Up to 24 months
Condylar courses straightness
Time frame: Up to 24 months
Amplitude of the condylar path
Time frame: Up to 24 months
Straightness of the condylar path
Time frame: Up to 24 months
Adverses events
Time frame: Up to 24 months
Pain assessment
Time frame: Up to 24 months
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Nov 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Review by Modjaw in people with Temporomandibular Joint Disorders, run by University Hospital, Montpellier at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 2 Nov 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Gap reduction between the interincisive point in mouth opening and the ordinate axis (time frame: Up to 24 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Nov 2026.