Nutrition DisordersNCT05747911
Dietary Advanced Glycation End Products and Migraine
An observational study of Nutrition Disorders and Migraine Disorders, run by Karabuk University at 1 site in Turkey (Türkiye).
Trial summary
Is dietary intake of advanced glycation different between individuals with and without migraine? Is there a difference between the groups in terms of energy and nutrients? The answers to these questions are sought. Read more about this study
- Who is it for?
- Ages 18 to 64 yearsHealthy volunteers can take part
- Conditions the study is for
- Nutrition Disorders, Migraine Disorders
- How many people
- 120 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Feb 2022to 1 Mar 2023
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 64 years
- All sexes
- Healthy volunteers accepted
- Adult
Study population: Adult individuals aged 19-64 who applied to Karabuk University Training and Research Hospital Neurology Clinic Headache Outpatient Clinic
Who may be able to join
- To be diagnosed with episodic migraine by an experienced neurologist,
- For the control group, patients who were not diagnosed with migraine but applied to the headache outpatient clinic
- Volunteer
Who cannot join
- Being younger than 19 years and older than 64 years of age, having a history of cardiovascular disease, hypertension, diabetes, cancer, liver and kidney disease or other neurological disorder (epilepsy, multiple sclerosis, stroke, traumatic brain injury, etc.), secondary headache, antilipidemic and glucose taking intolerance medications or vitamin-mineral supplements, following a special diet, and consuming less than 800 kcal or more than 4000 kcal per day
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Are Dietary Intake of Advanced Glycation End Products and Migraine Associated? A Case-control Study
Is dietary intake of advanced glycation different between individuals with and without migraine? Is there a difference between the groups in terms of energy and nutrients? The answers to these questions are sought.
- Conditions
- Nutrition Disorders, Migraine Disorders
- Medical subject headings
- Nutrition Disorders, Migraine Disorders
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Other
Groups will not be intervened. Only observational data will be used.
| Study group | Role | What they receive |
|---|---|---|
| Migraine | Not described | |
| Without Migraine | Not described |
What is being measured
The primary outcome is the main question the study is designed to answer.
Difference in dietary advanced glycation end products intake between groups
Is there a difference between the dietary intake of advanced glycation end products in individuals with migraine and healthy individuals? These values will be obtained from the food consumption records of the individuals. Intake of advanced glycation end product will be evaluated as ....kU/day.
Is there a difference between the energy and nutrient intake of individuals with migraine and healthy individuals?
Measured: 2 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted28 Feb 2023
- Study start1 Feb 2022
- Primary completion1 Sep 2022
- Study completion1 Mar 2023
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Nutrition DisordersStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Cross-sectional
- Enrolment
- 120 participants (actual)
Sponsor and investigators
- Lead sponsor
- Karabuk University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Büşra Demirer, Karabuk University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05747911
- Sponsor's protocol ID
- Busra Demirer
- Status last verified
- Feb 2023
- First submitted
- 16 Feb 2023
- Last updated
- 25 May 2023
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Demirer B, Ceylan D, Samur G. Evaluation of the Relationship Between Migraine and Dietary Advanced Glycation End Products. Nutr Bull. 2026 Jun;51(2):213-221. doi: 10.1111/nbu.70049. Epub 2026 Mar 2.
PubMed 41772735
Study at a glance
From the registry record, last updated by the sponsor on 25 May 2023. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Are Dietary Intake of Advanced Glycation End Products and Migraine Associated? A Case-control Study
- ClinicalTrials.gov ID
- NCT05747911
- Acronym / sponsor ID
- Busra Demirer
- Conditions
- Nutrition Disorders, Migraine Disorders
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 120 participants (actual)
- Lead sponsor
- Karabuk UniversityUniversity, hospital or other
- Study start
- 1 Feb 2022 (actual)
- Primary completion
- 1 Sep 2022 (actual)
- Study completion
- 1 Mar 2023 (actual)
- First posted
- 28 Feb 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Is dietary intake of advanced glycation different between individuals with and without migraine? Is there a difference between the groups in terms of energy and nutrients? The answers to these questions are sought.
Study design
- Observational model
- Case-control
- Time perspective
- Cross-sectional
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Migraine | – | – |
| Without Migraine | – | – |
Who may qualify
- Ages
- 18 to 64 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
- Study population
- Adult individuals aged 19-64 who applied to Karabuk University Training and Research Hospital Neurology Clinic Headache Outpatient Clinic
Key inclusion criteria (3 listed)
- To be diagnosed with episodic migraine by an experienced neurologist,
- For the control group, patients who were not diagnosed with migraine but applied to the headache outpatient clinic
- Volunteer
Key exclusion criteria (1 listed)
- Being younger than 19 years and older than 64 years of age, having a history of cardiovascular disease, hypertension, diabetes, cancer, liver and kidney disease or other neurological disorder (epilepsy, multiple sclerosis, stroke, traumatic brain injury, etc.), secondary headache, antilipidemic and glucose taking intolerance medications or vitamin-mineral supplements, following a special diet, and consuming less than 800 kcal or more than 4000 kcal per day
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Groups will not be intervened. Only observational data will be used. | Other | Migraine, Without Migraine |
Primary outcome
Difference in dietary advanced glycation end products intake between groups
Time frame: 2 months
Is there a difference between the dietary intake of advanced glycation end products in individuals with migraine and healthy individuals? These values will be obtained from the food consumption records of the individuals. Intake of advanced glycation end product will be evaluated as ....kU/day. Is there a difference between the energy and nutrient intake of individuals with migraine and healthy individuals?
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 25 May 2023.
- Derived from this study: PubMed 41772735Demirer B, Ceylan D, Samur G. Evaluation of the Relationship Between Migraine and Dietary Advanced Glycation End Products. Nutr Bull. 2026 Jun;51(2):213-221. doi: 10.1111/nbu.70049. Epub 2026 Mar 2.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Nutrition Disorders and Migraine Disorders, run by Karabuk University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 25 May 2023. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Difference in dietary advanced glycation end products intake between groups (time frame: 2 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT05747911, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 25 May 2023.