Chronic Ankle InstabilityNCT05757375
Mulligan Ankle Taping on Volleyball Players
A study testing Mulligan Manuel Therapy Consept in people with Chronic Ankle Instability and Mulligan, run by Istinye University at 1 site in Turkey (Türkiye).
Trial summary
34 volunteer professional volleyball players with (n=12) and without (n=22) CAI will include in the study. Mulligan ankle taping will apply. Measurements will take before and after the intervention. Muscle tone, stiffness, and elasticity will measure with MyotonPRO hand-held device. Read more about this study
- Who is it for?
- Ages 15 to 24 years, women onlyHealthy volunteers can take part
- Conditions the study is for
- Chronic Ankle Instability, Mulligan
- What is being tested?
- Mulligan Manuel Therapy Consept
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 34 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 22 Jan 2023to 20 May 2023
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 15 to 24 years
- Women only
- Healthy volunteers accepted
- Child, Adult
Who may be able to join
- Being between the ages of 15-24,
- Being a professional volleyball player,
- Training for 90 minutes at least 3 days a week,
- Turkish native speakers,
- For participants with chronic ankle instability, those with a Foot and Ankle Disability Index score below 90% and a Foot and Ankle Disability Index-Sport survey score below 75% were included.
Who cannot join
- An ankle sprain history in the last 6 weeks,
- Having a previous history of fracture in the lower extremity,
- Having bilateral chronic ankle instability,
- Pregnant athletes were excluded from the study.
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Istinye University
Istanbul, Zeytinburnu, 34010
About this study
Official title: Effects of Mulligan Ankle Taping in Volleyball Players With or Without Chronic Ankle Instability
34 volunteer professional volleyball players with (n=12) and without (n=22) CAI will include in the study. Mulligan ankle taping will apply. Measurements will take before and after the intervention. Muscle tone, stiffness, and elasticity will measure with MyotonPRO hand-held device. The static balance will measure with single leg stance test(SLST) while the eyes-closed, dynamic balance will measure with the Y balance test(YBT). Single leg hopping test(SLHT) will evaluate performance and an active position sense test will use for JPS. During the static and dynamic balance and performance tests, the ankle's confidence will be evaluated with the Visual Analog Scale (VAS). The study aimed to determine the effect of Mulligan fibular taping over the Tibialis Anterior(TA), Peroneus Longus(PL), Gastrocnemius Lateralis(GCL), and Medialis(GCM) muscles on muscle tone, stiffness, elasticity, as well as the performance, joint position sense(JPS), static and dynamic balance in female volleyball players with and without chronic ankle instability(CAI).
- Conditions
- Chronic Ankle Instability, Mulligan
- Being tested
- Mulligan Manuel Therapy Consept
- Keywords
- Chronic ankle instability, Mulligan fibular taping, muscle elasticity, muscle stiffness, muscle tone
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Mulligan Manuel Therapy ConseptOther
Mulligan ankle taping is a noninvasive, painless, low-cost, and easily applicable technique of the Mulligan manual therapy concept. It is frequently used in cases of ankle instability. In healthy people, it is a method to prevent ankle sprains.
| Study group | Role | What they receive |
|---|---|---|
| Volleyball players with Chronic Ankle Instability | Experimental | Before the taping application, the application area of all athletes will be shaved. It will be cleaned with an alcohol wipe before the application so that situations such as sweat or moisture do not reduce the effect of the banding. For taping, while the athlete lies in a supine position on a portable stretcher, the leg weight will be taken by placing the athlete's foot on the abdomen with slight knee and hip flexion. The rigid tape will be measured and cut obliquely starting approximately 2 cm anterior to the fibula and approximately 1 cm anterior to the lateral malleolus and ending in the middle of the anterior tibia region. To increase the strength of the banding, another band will be added to it. In the application, only banding will be preferred and mobilization will not be done. Receives: Other: Mulligan Manuel Therapy Consept |
| Volleybal players without Chronic Ankle Instability | Experimental | Before the taping application, the application area of all athletes will be shaved. It will be cleaned with an alcohol wipe before the application so that situations such as sweat or moisture do not reduce the effect of the banding. For taping, while the athlete lies in a supine position on a portable stretcher, the leg weight will be taken by placing the athlete's foot on the abdomen with slight knee and hip flexion. The rigid tape will be measured and cut obliquely starting approximately 2 cm anterior to the fibula and approximately 1 cm anterior to the lateral malleolus and ending in the middle of the anterior tibia region. To increase the strength of the banding, another band will be added to it. In the application, only banding will be preferred and mobilization will not be done. Receives: Other: Mulligan Manuel Therapy Consept |
What is being measured
The primary outcome is the main question the study is designed to answer.
Myotonometric Measurement
MyotonPRO is a wireless handheld device that objectively evaluates the viscoelastic properties of muscles such as tone, stiffness, and elasticity with numerical values. It creates a mechanical effect on the subcutaneous tissue and senses the response of the tissue. The 3-millimeter probe of the device is placed 90 degrees perpendicular to the subcutaneous tissue to be measured. With the measurement, muscle tone, stiffness, and elasticity are listed numerically. Muscle tone will be calculated in hz and muscle stiffness in N/m.
Measured: 4 weeks
Secondary outcomes (5)
Single Leg Stand Test with Eyes Closed
This test, which is used to evaluate the static balance ability, is applied with bare feet on a hard and flat surface. During the test, participants are asked to close their eyes, place both hands on the opposite shoulder, and pull the untested leg to the abdomen with a 90-degree flexion angle from the hip and knee. During the test, both legs should maintain this position without touching each other. The test is started as soon as the participant's untested foot is not in contact with the ground, and is terminated when it touches the ground. The test is repeated three times for both the right and left legs and the best result is referenced.
Measured: 4 weeks
Y Balance Test
It is a reported dynamic test with good reliability requiring strength, flexibility, and proprioception. It is a dynamic balance criterion applied to athletes and physically active people. This measurement requires a setup first. Three equal-length tapes adhere to the floor with 90°, 135°, and 135° angles between them, and a Y shape is obtained. The directions to be tested are anterior, posterolateral, and posteromedial. It is a highly reliable test to determine the risk of CABI and lower extremity injury.
Measured: 4 weeks
Single Leg Hop Test
It is a functional performance test. This measurement requires a setup first. The 3-meter tape is placed on the floor. The athlete is asked to jump as far as possible and stay on one leg in the band. The test is invalidated when the participant touches the floor with their untested foot or takes a few more small jumps to maintain their balance after the jump. The distance from the starting level of the band to the heel contact at the end of the jump is measured. This test is repeated 3 times until a successful jump is achieved and the best result is included in the evaluation.
Measured: 4 weeks
Joint Position Test
Joint position sense is the ability of the athlete to perceive the joint angle and repeat the same joint angle even if the extremity position changes. The active position sense test is frequently used, especially in the clinic, due to its easy application. While the test athlete's eyes are closed, he/she sits in such a way that the hip flexion angle of 90° and the knee flexion angle of 120° is achieved and the sole is in full contact with the ground. The difference between the right and left dorsiflexion angles is measured with a smartphone from the goniometer application. Dorsiflexion measurement is made by following the midline of the 5th metatarsal bone with a goniometer placed in the lateral malleolus. The athlete's ankle to be tested is passively brought to 10° dorsiflexion and returned to the starting point. Afterward, the athlete is asked to actively bring his ankle to the same angle. The test is repeated three times for both ankles. By subtracting the angle made by the athlete
Measured: 4 weeks
Confidence in the Ankle
In order to evaluate the confidence of the athletes in the balance and performance tests, they are asked to score the confidence ratios before and after the intervention with the Visual Analogue Scale. The VAS assessment is performed for the blindfolded one-leg stance test, the Y-star balance test (anterior, posteromedial, and posterolateral aspects), and the one-leg hop tests. In order not to mislead the individual, each participant was asked, "How much was your confidence in your ankle during the test?" for each parameter. the question is asked. He is asked to show his confidence in the ankle on a 10 cm line and the distance is measured.
Measured: 4 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted7 Mar 2023
- Study start22 Jan 2023
- Primary completion12 May 2023
- Study completion20 May 2023
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Chronic Ankle InstabilityStudies of the same condition, open and under way.
- More trials run by Istinye UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Investigator
- Enrolment
- 34 participants (actual)
Sponsor and investigators
- Lead sponsor
- Istinye University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Özge Ecem Şenel, Istinye University
- Investigators
- ÖZGE ECEM E ŞENEL, PT, Principal investigator, İSTİNYE UNIVERSITY
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05757375
- Sponsor's protocol ID
- 10840098
- Status last verified
- Aug 2025
- First submitted
- 12 Jan 2023
- Last updated
- 21 Aug 2025
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 21 Aug 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Mulligan Ankle Taping in Volleyball Players With or Without Chronic Ankle Instability
- ClinicalTrials.gov ID
- NCT05757375
- Acronym / sponsor ID
- 10840098
- Conditions
- Chronic Ankle Instability, Mulligan
- Keywords
- Chronic ankle instability, Mulligan fibular taping, muscle elasticity, muscle stiffness, muscle tone
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 34 participants (actual)
- Lead sponsor
- Istinye UniversityUniversity, hospital or other
- Study start
- 22 Jan 2023 (actual)
- Primary completion
- 12 May 2023 (actual)
- Study completion
- 20 May 2023 (actual)
- First posted
- 7 Mar 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
34 volunteer professional volleyball players with (n=12) and without (n=22) CAI will include in the study. Mulligan ankle taping will apply. Measurements will take before and after the intervention. Muscle tone, stiffness, and elasticity will measure with MyotonPRO hand-held device. The static balance will measure with single leg stance test(SLST) while the eyes-closed, dynamic balance will measure with the Y balance test(YBT). Single leg hopping test(SLHT) will evaluate performance and an active position sense test will use for JPS. During the static and dynamic balance and performance tests, the ankle's confidence will be evaluated with the Visual Analog Scale (VAS). The study aimed to determine the effect of Mulligan fibular taping over the Tibialis Anterior(TA), Peroneus Longus(PL), Gastrocnemius Lateralis(GCL), and Medialis(GCM) muscles on muscle tone, stiffness, elasticity, as well as the performance, joint position sense(JPS), static and dynamic balance in female volleyball players with and without chronic ankle instability(CAI).
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (investigator)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Volleyball players with Chronic Ankle Instability | Experimental | Other: Mulligan Manuel Therapy ConseptBefore the taping application, the application area of all athletes will be shaved. It will be cleaned with an alcohol wipe before the application so that situations such as sweat or moisture do not reduce the effect of the banding. For taping, while the athlete lies in a supine position on a portable stretcher, the leg weight will be taken by placing the athlete's foot on the abdomen with slight knee and hip flexion. The rigid tape will be measured and cut obliquely starting approximately 2 cm anterior to the fibula and approximately 1 cm anterior to the lateral malleolus and ending in the middle of the anterior tibia region. To increase the strength of the banding, another band will be added to it. In the application, only banding will be preferred and mobilization will not be done. |
| Volleybal players without Chronic Ankle Instability | Experimental | Other: Mulligan Manuel Therapy ConseptBefore the taping application, the application area of all athletes will be shaved. It will be cleaned with an alcohol wipe before the application so that situations such as sweat or moisture do not reduce the effect of the banding. For taping, while the athlete lies in a supine position on a portable stretcher, the leg weight will be taken by placing the athlete's foot on the abdomen with slight knee and hip flexion. The rigid tape will be measured and cut obliquely starting approximately 2 cm anterior to the fibula and approximately 1 cm anterior to the lateral malleolus and ending in the middle of the anterior tibia region. To increase the strength of the banding, another band will be added to it. In the application, only banding will be preferred and mobilization will not be done. |
Who may qualify
- Ages
- 15 to 24 years
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult
Key inclusion criteria (5 listed)
- Being between the ages of 15-24,
- Being a professional volleyball player,
- Training for 90 minutes at least 3 days a week,
- Turkish native speakers,
- For participants with chronic ankle instability, those with a Foot and Ankle Disability Index score below 90% and a Foot and Ankle Disability Index-Sport survey score below 75% were included.
Key exclusion criteria (4 listed)
- An ankle sprain history in the last 6 weeks,
- Having a previous history of fracture in the lower extremity,
- Having bilateral chronic ankle instability,
- Pregnant athletes were excluded from the study.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Mulligan Manuel Therapy ConseptMulligan ankle taping is a noninvasive, painless, low-cost, and easily applicable technique of the Mulligan manual therapy concept. It is frequently used in cases of ankle instability. In healthy people, it is a method to prevent ankle sprains. | Other | Volleybal players without Chronic Ankle Instability, Volleyball players with Chronic Ankle Instability |
Primary outcome
Myotonometric Measurement
Time frame: 4 weeks
MyotonPRO is a wireless handheld device that objectively evaluates the viscoelastic properties of muscles such as tone, stiffness, and elasticity with numerical values. It creates a mechanical effect on the subcutaneous tissue and senses the response of the tissue. The 3-millimeter probe of the device is placed 90 degrees perpendicular to the subcutaneous tissue to be measured. With the measurement, muscle tone, stiffness, and elasticity are listed numerically. Muscle tone will be calculated in hz and muscle stiffness in N/m.
5 secondary outcomes
Single Leg Stand Test with Eyes Closed
Time frame: 4 weeks
Y Balance Test
Time frame: 4 weeks
Single Leg Hop Test
Time frame: 4 weeks
Joint Position Test
Time frame: 4 weeks
Confidence in the Ankle
Time frame: 4 weeks
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 21 Aug 2025.
- Individual participant dataSharing planned: Undecided
Related trials for Chronic Ankle Instability
Recruiting
The Effects of Vestibulo-Ocular Reflex Exercises Added to Postural Stabilization Training in Amateur Athletes With Chronic Ankle Instability
Ankle Sprain, Ankle Sprain Strain
Recruiting
The Effects of Vestibulo-Ocular Reflex Exercises Added to Postural Stabilization Training in Chronic Ankle Instability
Ankle Sprains, Ankle Sprain Strain
Recruiting
Functional Biomechanical Analysis in Patients Who Underwent Lateral Ankle Ligament Repair With Augmentation
Chronic Lateral Ankle Instability
Not yet recruiting
Collagen Scaffold Bioaugmentation for ATFL Repair in Chronic Ankle Instability
Chronic Ankle Instability, Ankle Sprain
Recruiting
Comparison of the Effects of Hip and Ankle Focused Progressive Exercise Training on Lower Extremity Function in Athletes With Chronic Ankle Instability
Ankle Sprains
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
ÖZGE ECEM E ŞENEL, PT principal investigator
İSTİNYE UNIVERSITY
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Mulligan Manuel Therapy Consept in people with Chronic Ankle Instability and Mulligan, run by Istinye University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 21 Aug 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Myotonometric Measurement (time frame: 4 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 21 Aug 2025.