COVID-19NCT05770505
Use of E-health Based Exercise Intervention After COVID-19
A study testing Exercise training using an e-health tool in people with COVID-19, run by Norwegian University of Science and Technology at 1 site in Norway.
Trial summary
Reduced subjective and objective functional capacity performance are reported after COVID-19 in a large proportion of subjects. The aim of this study is to examine the feasibility and effect of using an e-health tool for guidance and tracking of exercise training in a general population of adults previously infected… Read more about this study
- Who is it for?
- Ages 18 to 59 yearsHealthy volunteers can take part
- Conditions the study is for
- COVID-19
- What is being tested?
- Exercise training using an e-health tool
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 77 participants
- Where
- 1 siteNorway
- Study dates
- 17 Apr 2023to 31 Dec 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 59 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Persons who have undergone COVID-19 disease
- People who struggle to be physically active enough as a result of corona disease
- People who experience reduced physical fitness as a result of corona disease
Who cannot join
- -- more than 100 AQ per week (calculated from self-reported activity level)
- uncontrolled hypertension (high blood pressure) (over 200/110).
- symptomatic valve failure, hypertrophic cardiomyopathy, unstable angina, pulmonary
- hypertension, heart failure and/or severe rhythm disturbances
- cancer that makes participation impossible or exercise contraindicated. Considered individually in consultation with the attending physician.
- chronic contagious infectious diseases.
- Participates in other studies that are not compatible with participation in this project
- Post-exertional symptom exacerbation (PESE)/post-exertional malaise (PEM)/post-exertional neuroimmune exhaustion (PENE).
Trial locations and contacts
1 site in 1 country.
Norway1 site
Norwegian University of Science and Technology, Faculty of medicine, Department of circulation and medical imaging,
Trondheim, 7006
About this study
Official title: Effect E-health Based Exercise Intervention After COVID-19
Reduced subjective and objective functional capacity performance are reported after COVID-19 in a large proportion of subjects. The aim of this study is to examine the feasibility and effect of using an e-health tool for guidance and tracking of exercise training in a general population of adults previously infected by COVID-19.
Read the detailed description
Both hospitalized and non-hospitalized persons who have undergone extensive multi-disciplinary rehabilitation programs report significantly improved physical function after rehabilitation. Exercise training may be the key intervention to improve fitness and subjective complaints such as fatigue, low physical fitness and dyspnea after COVID-19 infection. However, traditional group-based exercise training or self-training programs at fitness centers have been shut down during the pandemic, and home-based interventions are warranted. To overcome the limitations and costs of a fitness center/personal trainer-based intervention study, more knowledge on the effectiveness and efficacy of using an e-Health system to recruit, train and monitor participants after illness are needed.
- Conditions
- COVID-19
- Being tested
- Exercise training using an e-health tool
- Medical subject headings
- COVID-19
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Exercise training using an e-health toolBehavioural
Experimental: Exercise training will be guided by using the e-health tool MIA Health, with the possibility for digital communication between the participants and study personnel The participants will receive wearables that record heart rate. Participants will be encouraged to achieve 100 Activity Quotient (AQ) equivalents per week Control: No follow-up
| Study group | Role | What they receive |
|---|---|---|
| Supervised exercise | Experimental | Not described Receives: Behavioral: Exercise training using an e-health tool |
| Control group | No intervention | Not described |
What is being measured
The primary outcome is the main question the study is designed to answer.
Cardiorespiratory fitness
Peak oxygen uptake
Measured: After 6 months intervention
Feasibilty
Measured as acceptability and adherence
Measured: After 6 months intervention
Secondary outcomes (2)
Lung function
Spirometry
Measured: After 6 months intervention
Quality of life
Questionnaires (RAND-12)
Measured: After 6 months intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted15 Mar 2023
- Study start17 Apr 2023
- Primary completion31 May 2024
- Study completion31 Dec 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for COVID-19Studies of the same condition, open and under way.
- More trials run by Norwegian University of Science and TechnologyThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 77 participants (actual)
Sponsor and investigators
- Lead sponsor
- Norwegian University of Science and Technology
- Sponsor type
- University, hospital or other
- Collaborators
- University of Oslo
- Responsible party
- Sponsor
- Investigators
- Dorthe Stensvold Stensvold, Principal investigator, Dorthe Stensvold, Professor, NTNU
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05770505
- Sponsor's protocol ID
- 479316
- Status last verified
- Dec 2025
- First submitted
- 13 Mar 2023
- Last updated
- 5 Jan 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 5 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect E-health Based Exercise Intervention After COVID-19
- ClinicalTrials.gov ID
- NCT05770505
- Acronym / sponsor ID
- 479316
- Conditions
- COVID-19
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 77 participants (actual)
- Lead sponsor
- Norwegian University of Science and TechnologyUniversity, hospital or other
- Collaborators
- University of Oslo
- Study start
- 17 Apr 2023 (actual)
- Primary completion
- 31 May 2024 (actual)
- Study completion
- 31 Dec 2024 (actual)
- First posted
- 15 Mar 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Reduced subjective and objective functional capacity performance are reported after COVID-19 in a large proportion of subjects. The aim of this study is to examine the feasibility and effect of using an e-health tool for guidance and tracking of exercise training in a general population of adults previously infected by COVID-19.
Detailed description
Both hospitalized and non-hospitalized persons who have undergone extensive multi-disciplinary rehabilitation programs report significantly improved physical function after rehabilitation. Exercise training may be the key intervention to improve fitness and subjective complaints such as fatigue, low physical fitness and dyspnea after COVID-19 infection. However, traditional group-based exercise training or self-training programs at fitness centers have been shut down during the pandemic, and home-based interventions are warranted. To overcome the limitations and costs of a fitness center/personal trainer-based intervention study, more knowledge on the effectiveness and efficacy of using an e-Health system to recruit, train and monitor participants after illness are needed.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Supervised exercise | Experimental | Behavioral: Exercise training using an e-health tool |
| Control group | No intervention | – |
Who may qualify
- Ages
- 18 to 59 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (3 listed)
- Persons who have undergone COVID-19 disease
- People who struggle to be physically active enough as a result of corona disease
- People who experience reduced physical fitness as a result of corona disease
Key exclusion criteria (8 listed)
- -- more than 100 AQ per week (calculated from self-reported activity level)
- uncontrolled hypertension (high blood pressure) (over 200/110).
- symptomatic valve failure, hypertrophic cardiomyopathy, unstable angina, pulmonary
- hypertension, heart failure and/or severe rhythm disturbances
- cancer that makes participation impossible or exercise contraindicated. Considered individually in consultation with the attending physician.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Exercise training using an e-health toolExperimental: Exercise training will be guided by using the e-health tool MIA Health, with the possibility for digital communication between the participants and study personnel The participants will receive wearables that record heart rate. Participants will be encouraged to achieve 100 Activity Quotient (AQ) equivalents per week Control: No follow-up | Behavioural | Supervised exercise |
Primary outcome
Cardiorespiratory fitness
Time frame: After 6 months intervention
Peak oxygen uptake
Feasibilty
Time frame: After 6 months intervention
Measured as acceptability and adherence
2 secondary outcomes
Lung function
Time frame: After 6 months intervention
Quality of life
Time frame: After 6 months intervention
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 Jan 2026.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Dorthe Stensvold Stensvold principal investigator
Dorthe Stensvold, Professor, NTNU
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Exercise training using an e-health tool in people with COVID-19, run by Norwegian University of Science and Technology at 1 site in Norway.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 5 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Norway. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Cardiorespiratory fitness (time frame: After 6 months intervention). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Jan 2026.