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AgedNCT05808426

Benefits of Online Mahjong by Older Adults

A study testing Bonus Winner Mahjong in people with Aged, run by National Yang Ming Chiao Tung University at 1 site in Taiwan.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

This study aims to examine the clinical efficacy of online Mahjong in improving physical health, cognitive performance, happiness, laboratory biomarkers, and structural brain imaging (magnetic resonance imaging, MRI) by a randomized controlled trial design, and hopefully to expand the scope of healthy aging… Read more about this study

Who is it for?
Ages 55 to 74 yearsHealthy volunteers can take part
Conditions the study is for
Aged
What is being tested?
Bonus Winner Mahjong
Type of treatment
Medical device
Could I receive a placebo?
No, everyone receives an active treatment
How many people
60 participants
Where
1 siteTaiwan
Study dates
28 Jul 2020to 20 Mar 2022
Phase
Interventional
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 55 to 74 years
  • All sexes
  • Healthy volunteers accepted
  • Adult, Older adult

Who may be able to join

  • Age ≥ 55 years old.
  • More than 6 years of formal education.
  • Can communicate in Mandarin and Taiwanese.
  • Can accept MRI examination without claustrophobia.
  • Can understand the research process, meet the requirements of the research, and can sign the consent form and participate in the subject.

Who cannot join

  • Have engaged in any Mahjong games in the past three months.
  • Engaged in Mahjong games more than three times per year in the past three years.

Trial locations and contacts

1 site in 1 country.

Taiwan1 site

  • Center for Geriatrics and Gerontology, Taipei Veterans General Hospital

    Taipei, 112

Other trials in Taiwan

About this study

Official title: Randomized Trial of Online Mahjong Intervention to Promote Cognitive Function and Health Status in Community-dwelling Middle Aged and Older Adults.

This study aims to examine the clinical efficacy of online Mahjong in improving physical health, cognitive performance, happiness, laboratory biomarkers, and structural brain imaging (magnetic resonance imaging, MRI) by a randomized controlled trial design, and hopefully to expand the scope of healthy aging intervention activities with strong scientific evidence.

Read the detailed description

Psychomotor function among older adult's decline was associated with reducing people interaction during pandemic has been reported. The research focused on examining the benefit and efficacy of digital based Mahjong games with 6-month intervention is very limited or none. A random control design was conducted with comparing intervention group and with control group, followed the CONSORT guidelines. Six months program was intervened to ensure the impact of the intervention. Primary outcome is brain imagery changes between groups, which showed changes in temporal fusiform cortex but not in resting-state fMRI. The total score of MoCA, delayed recall was increase from baseline to after intervention in experimental group. Overall cognitive function and visuospatial/executive, in experimental group improved more than control group. Improving self-rating daily health status as associated with achievement rate of Mahjong game. Increasing level of resilience was associated with demoralization level, subtraction of cognitive function, and 5th month walking steps. In addition, affecting incased self -rate overall heath was related to demoralization. In short, online mahjong intervention has positive impact on older adults in cognitive function , resilience, demoralization and overall quality of life.

Conditions
Aged
Being tested
Bonus Winner Mahjong
Keywords
online Mahjong, physical activity, cognitive function, quality of life in older adults
Medical subject headings
Motor Activity

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Bonus Winner MahjongDevice

    Bonus Winner Mahjong developed by Bonus Winner Online Entertainment Co., Ltd. The participants in experimental group played three times a week, each time requiring at least lasting 30 minutes, for half of a year.

Study groups in NCT05808426
Study groupRoleWhat they receive
observation with no intervention groupNo interventionThe control group only performed routine data collection; the research assistant asked the subjects about their usual activities by telephone every month to understand their physical activity in this half of the year.
Mahjong groupExperimentalThe experimental group intervened a Bonus Winner Mahjong developed by Bonus Winner Online Entertainment Co., Ltd. The participants in experimental group played three times a week, each time requiring at least lasting 30 minutes, for half of a year.
Receives: Device: Bonus Winner Mahjong

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Change in MRI study from baseline to 6 months in the intervention group.

    Change in MRI study from baseline to 6 months in the intervention group.

    Measured: baseline and 6 months

Secondary outcomes (5)

  1. Montreal Cognitive Assessment (MoCA)

    Cognitive function measure by MoCA , which comprise a 30-question test.Score range: 0-30, and a score of 26 and higher is considered normal.

    Measured: baseline and 6 months

  2. EuroQol instrument (EQ-5D)

    Quality of life measure by EQ-5D, which include five questions on mobility, self care, pain, usual activities, and psychological status. Score range: There are three level of the answers for each question, the maximum score of 1 refers to the best condition without problem, and higher scores refers more severe of the issue. Moreover, the visual analogue scale (VAS) which from 0-100, higher score indicating better health status.

    Measured: baseline and 6 months

  3. International Physical Activity Questionnaire (IPAQ)

    Physical activity measured by IPAQ, indicates that spent being physically active within the prior 7 days. Score range: There are no established thresholds for presenting MET-minutes, the IPAQ Research Committee proposes that reported as comparisons of median values and interquartile ranges for different populations.

    Measured: baseline and 6 months

  4. Brief Resilience Scale (BRS)

    Resilience measured by BRS to assess ability to bounce back or recover from stress and adversity. Score range: 6-30, and higher scores refers to higher level of resilience.

    Measured: baseline and 6 months

  5. Demoralization Scale-Mandarin Version (DS-MV)

    Demoralization measure by DS-MV, comprised 24 items and each rated on a five-point Likert scale.Score range: 0-96, and cut-off point score ≥30 was considered to identified demoralization.

    Measured: baseline and 6 months

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted11 Apr 2023
  2. Study start28 Jul 2020
  3. Primary completion1 Nov 2021
  4. Study completion20 Mar 2022

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Supportive care
Allocation
Randomised
Intervention model
Parallel groups
Model description
This study is a single-blind, parallel-group randomized controlled trial. Eligible participants were allocated randomly 1:1, without stratification, to either the intervention or the control group, according to a computer-generated random number sequence.
Masking
Single blind
Who is masked
Investigator
Enrolment
60 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT05808426
Sponsor's protocol ID
YM108123F_M
Status last verified
Jun 2020
First submitted
29 Mar 2023
Last updated
19 Apr 2023
Results posted
No
FDA-regulated drug
No
FDA-regulated device
No

Publications

  • Tung HH, Kuo CY, Lee PL, Chang CW, Chou KH, Chen KE, Lin CP, Liang CK, Chen LK. Digital Mahjong-Based Cognitive Engagement Intervention for Older Adults: Randomized Controlled Trial. JMIR Aging. 2026 Jul 23;9:e85339. doi: 10.2196/85339.

    PubMed 42492920

Questions about this trial

What is this clinical trial studying?

A study testing Bonus Winner Mahjong in people with Aged, run by National Yang Ming Chiao Tung University at 1 site in Taiwan.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 5 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 19 Apr 2023. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Taiwan. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Change in MRI study from baseline to 6 months in the intervention group. (time frame: baseline and 6 months). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT05808426, which also lists 1 linked publication.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 Apr 2023.

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