Intracranial Arterial StenosisICAS-YoungNCT05844176
Intracranial Arterial Stenosis in Young Patients
An observational study of Intracranial Arterial Stenosis, run by Capital Medical University at 4 sites in China.
Trial summary
The goal of this study is to evaluate the characteristic of intracranial arterial stenosis among young patients. Read more about this study
- Who is it for?
- Ages Up to 45 years
- Conditions the study is for
- Intracranial Arterial Stenosis
- What is being tested?
- Routine clinical treatment
- How many people
- 500 participants
- Where
- 4 sitesChina
- Study dates
- 1 Jun 2022to 1 Oct 2031
- How long will I take part?
- 3 Years
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Up to 45 years
- All sexes
- No healthy volunteers
- Child, Adult
Study population: Patients with intracranial arterial stenosis
Who may be able to join
- age < 45 years.
- stenosis of a major intracranial artery.
Who cannot join
- -
Trial locations and contacts
4 sites in 1 country.
China4 sites
Xuanwu Hospital, Capital Medical University
Beijing, 100053
The Second Hospital of Hebei Medical University
Shijiazhuang, Hebei
Suzhou Municipal Hoapital
Suzhou, Anhui
The First Affiliated Hospital of Zhengzhou University
Zhengzhou
About this study
Official title: Intracranial Arterial Stenosis in Young Patients: a Multicenter Longitudinal Cohort Study
The goal of this study is to evaluate the characteristic of intracranial arterial stenosis among young patients.
- Conditions
- Intracranial Arterial Stenosis
- Being tested
- Routine clinical treatment
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Routine clinical treatmentOther
Routine clinical treatment is based on the latest international and local guidelines
| Study group | Role | What they receive |
|---|---|---|
| Symptomatic intracranial arterial stenosis | Not described Receives: Other: Routine clinical treatment | |
| Asymptomatic intracranial arterial stenosis | Not described Receives: Other: Routine clinical treatment |
What is being measured
The primary outcome is the main question the study is designed to answer.
Ischemic stroke in territory of qualifying artery
Measured: 1 year
Secondary outcomes (4)
Ischemic stroke in other territory
Measured: 1 year
Any stroke
Measured: 1 year
Death
Measured: 1 year
Stenosis of the intracranial artery
Measured: 1 year
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted6 May 2023
- Study start1 Jun 2022
- Primary completion1 Aug 2027 (estimated)
- Study completion1 Oct 2031 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Intracranial Arterial StenosisStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 500 participants (estimated)
- Target duration
- 3 Years
Sponsor and investigators
- Lead sponsor
- Capital Medical University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ji Xunming,MD,PhD, Capital Medical University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05844176
- Sponsor's protocol ID
- ICAS-Young
- Acronym
- ICAS-Young
- Status last verified
- Aug 2026
- First submitted
- 25 Apr 2023
- Last updated
- 17 Aug 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 17 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Intracranial Arterial Stenosis in Young Patients: a Multicenter Longitudinal Cohort Study
- ClinicalTrials.gov ID
- NCT05844176
- Acronym / sponsor ID
- ICAS-Young / ICAS-Young
- Conditions
- Intracranial Arterial Stenosis
- Study type
- Observational
- Recruitment status
- Active, not recruiting
- Enrolment
- 500 participants (estimated)
- Lead sponsor
- Capital Medical UniversityUniversity, hospital or other
- Study start
- 1 Jun 2022 (actual)
- Primary completion
- 1 Aug 2027 (estimated)
- Study completion
- 1 Oct 2031 (estimated)
- First posted
- 6 May 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this study is to evaluate the characteristic of intracranial arterial stenosis among young patients.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Target follow-up
- 3 Years
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Symptomatic intracranial arterial stenosis | – | Other: Routine clinical treatment |
| Asymptomatic intracranial arterial stenosis | – | Other: Routine clinical treatment |
Who may qualify
- Ages
- Up to 45 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult
- Study population
- Patients with intracranial arterial stenosis
Key inclusion criteria (2 listed)
- age < 45 years.
- stenosis of a major intracranial artery.
Key exclusion criteria (1 listed)
- -
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Routine clinical treatmentRoutine clinical treatment is based on the latest international and local guidelines | Other | Asymptomatic intracranial arterial stenosis, Symptomatic intracranial arterial stenosis |
Primary outcome
Ischemic stroke in territory of qualifying artery
Time frame: 1 year
4 secondary outcomes
Ischemic stroke in other territory
Time frame: 1 year
Any stroke
Time frame: 1 year
Death
Time frame: 1 year
Stenosis of the intracranial artery
Time frame: 1 year
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Aug 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
4 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Intracranial Arterial Stenosis, run by Capital Medical University at 4 sites in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 17 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 4 sites in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Ischemic stroke in territory of qualifying artery (time frame: 1 year). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Aug 2026.