Parkinson DiseaseNCT05855161
Effectiveness of Rebound Therapy in Parkinson's Patients
A study testing Rebound therapy and Exercises on a stable surface in people with Parkinson Disease, run by Gazi University at 1 site in Turkey (Türkiye).
Trial summary
Today, physiotherapy approaches in Parkinson's Disease (PD) form the basis of optimal treatment together with medical and surgical treatment. It is stated that various rehabilitation interventions may be effective in the field of physiotherapy. Read more about this study
- Who is it for?
- Ages 40 to 80 years
- Conditions the study is for
- Parkinson Disease
- What is being tested?
- Rebound therapy and Exercises on a stable surface
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 17 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 10 Apr 2023to 10 Dec 2023
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 to 80 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- 40-80 years of age
- Having diagnosed with "Parkinson's Disease" by a specialist physician
- Having between 1-3 stages according to the Hoehn and Yahr Scale
- Mini-Mental Test score more than or equal 24
Who cannot join
- Any orthopedic, vision, hearing, cardiovascular, or perception problems that may affect the research results
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Sivas Cumhuriyet University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation
Sivas
About this study
Official title: Effectiveness of Rebound Therapy on Balance and Gait in Parkinson's Patients
Today, physiotherapy approaches in Parkinson's Disease (PD) form the basis of optimal treatment together with medical and surgical treatment. It is stated that various rehabilitation interventions may be effective in the field of physiotherapy. The frequently preferred among these rehabilitation interventions is the conventional treatment approach. In the conventional treatment, various exercises are preferred to improve balance and walking, as well as stretching and strengthening. On the other hand, rebound therapy require strong integration of the neuromuscular system and provide more active use of lower extremity muscle strength. Rebound therapy have been shown to be effective in improving balance in many neurological disease groups, but there is very little study on rebound therapy in PD. It was shown that rebound therapy improve proprioceptive sense, joint range of motion and quality of life. On the other hand, no study has been found showing its effect on balance and walking. Therefore, there is a need to investigate the effectiveness of rebound therapy on balance and walking.
Read the detailed description
This study is a randomized controlled study. The patients will be randomly divided into two groups as rebound and control. The rebound group will perform exercises on a trampoline, consisting of 15 minutes of trunk and extremity stretching, 10 minutes of walking, and approximately 30 minutes of task-oriented exercises, twice a week for six weeks. While the control group will follow the same program as the rebound group, they will only perform task-oriented exercises on a stable surface, unlike the rebound group. As the outcome measures, disease severity and disability, balance, and gait performance will be evaluated.
- Conditions
- Parkinson Disease
- Being tested
- Rebound therapy, Exercises on a stable surface
- Keywords
- Parkinson's disease, rebound therapy, task oriented training, balance and walking performance
- Medical subject headings
- Parkinson Disease
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Rebound therapyOther
Participants will receive exercise-based training on a trampoline
Exercises on a stable surfaceOther
Participants will receive exercise-based training on a stable surface
| Study group | Role | What they receive |
|---|---|---|
| Rebound therapy | Experimental | The group that will perform exercises on a trampoline. Receives: Other: Rebound therapy |
| Control group | Experimental | The group that will perform exercises on a stable surface. Receives: Other: Exercises on a stable surface |
What is being measured
The primary outcome is the main question the study is designed to answer.
Static Balance- Baseline
Assessment will be made with the Biodex Balance System
Measured: Assessment will be conducted before the intervention
Static Balance- Post intervention
Assessment will be made with the Biodex Balance System
Measured: Assessment will be conducted immediately after the intervention
Gait speed- Baseline
Assessment will be made with the BTS G-Walk, (BTS SpA, Via della Croce Rossa, 11 Padova, Italy; SN: 0213-0378) during gait
Measured: Assessment will be conducted before the intervention
Gait speed- Post intervention
Assessment will be made with the BTS G-Walk, (BTS SpA, Via della Croce Rossa, 11 Padova, Italy; SN: 0213-0378) during gait
Measured: Assessment will be conducted immediately after the intervention
Knee strength- Baseline
Assessment will be made with an isokinetic dynamometer (Cybex Humac Norm Testing and Rehabilitation System, CSMI, USA)
Measured: Assessment will be conducted before the intervention
Knee strength-Post intervention
Assessment will be made with an isokinetic dynamometer (Cybex Humac Norm Testing and Rehabilitation System, CSMI, USA)
Measured: Assessment will be conducted immediately after the intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted11 May 2023
- Study start10 Apr 2023
- Primary completion10 Nov 2023
- Study completion10 Dec 2023
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for Parkinson DiseaseStudies of the same condition, open and under way.
- More trials run by Gazi UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Two groups as rebound group and control group
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 17 participants (actual)
Sponsor and investigators
- Lead sponsor
- Gazi University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Sefa Eldemir, Cumhuriyet University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05855161
- Sponsor's protocol ID
- 5-PD-Rebound therapy-RCT
- Status last verified
- Dec 2023
- First submitted
- 3 May 2023
- Last updated
- 28 Dec 2023
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: There is no plan to make PD data but when the statistical analysis of all data is made, all results will be shared.
Publications
Daneshvar P, Ghasemi G, Zolaktaf V, Karimi MT. Comparison of the Effect of 8-Week Rebound Therapy-Based Exercise Program and Weight-Supported Exercises on the Range of Motion, Proprioception, and the Quality of Life in Patients with Parkinson's Disease. Int J Prev Med. 2019 Aug 12;10:131. doi: 10.4103/ijpvm.IJPVM_527_18. eCollection 2019.
PubMed 31516672Eldemir S, Polat EA, Gokdogan CM, Eldemir K, Guclu-Gunduz A, Yilmaz R, Akbostanci MC, Yazici G. The effect of rebound therapy in Parkinson's disease: A single-blinded randomized controlled trial. Gait Posture. 2026 Mar;125:110105. doi: 10.1016/j.gaitpost.2026.110105. Epub 2026 Jan 25.
PubMed 41592453
Study at a glance
From the registry record, last updated by the sponsor on 28 Dec 2023. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effectiveness of Rebound Therapy on Balance and Gait in Parkinson's Patients
- ClinicalTrials.gov ID
- NCT05855161
- Acronym / sponsor ID
- 5-PD-Rebound therapy-RCT
- Conditions
- Parkinson Disease
- Keywords
- Parkinson's disease, rebound therapy, task oriented training, balance and walking performance
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 17 participants (actual)
- Lead sponsor
- Gazi UniversityUniversity, hospital or other
- Study start
- 10 Apr 2023 (actual)
- Primary completion
- 10 Nov 2023 (actual)
- Study completion
- 10 Dec 2023 (actual)
- First posted
- 11 May 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Today, physiotherapy approaches in Parkinson's Disease (PD) form the basis of optimal treatment together with medical and surgical treatment. It is stated that various rehabilitation interventions may be effective in the field of physiotherapy. The frequently preferred among these rehabilitation interventions is the conventional treatment approach. In the conventional treatment, various exercises are preferred to improve balance and walking, as well as stretching and strengthening. On the other hand, rebound therapy require strong integration of the neuromuscular system and provide more active use of lower extremity muscle strength. Rebound therapy have been shown to be effective in improving balance in many neurological disease groups, but there is very little study on rebound therapy in PD. It was shown that rebound therapy improve proprioceptive sense, joint range of motion and quality of life. On the other hand, no study has been found showing its effect on balance and walking. Therefore, there is a need to investigate the effectiveness of rebound therapy on balance and walking.
Detailed description
This study is a randomized controlled study. The patients will be randomly divided into two groups as rebound and control. The rebound group will perform exercises on a trampoline, consisting of 15 minutes of trunk and extremity stretching, 10 minutes of walking, and approximately 30 minutes of task-oriented exercises, twice a week for six weeks. While the control group will follow the same program as the rebound group, they will only perform task-oriented exercises on a stable surface, unlike the rebound group. As the outcome measures, disease severity and disability, balance, and gait performance will be evaluated.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 2
- Model description
- Two groups as rebound group and control group
| Arm | Type | Receives |
|---|---|---|
| Rebound therapy | Experimental | Other: Rebound therapyThe group that will perform exercises on a trampoline. |
| Control group | Experimental | Other: Exercises on a stable surfaceThe group that will perform exercises on a stable surface. |
Who may qualify
- Ages
- 40 to 80 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- 40-80 years of age
- Having diagnosed with "Parkinson's Disease" by a specialist physician
- Having between 1-3 stages according to the Hoehn and Yahr Scale
- Mini-Mental Test score more than or equal 24
Key exclusion criteria (1 listed)
- Any orthopedic, vision, hearing, cardiovascular, or perception problems that may affect the research results
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Rebound therapyParticipants will receive exercise-based training on a trampoline | Other | Rebound therapy |
| Exercises on a stable surfaceParticipants will receive exercise-based training on a stable surface | Other | Control group |
Primary outcome
Static Balance- Baseline
Time frame: Assessment will be conducted before the intervention
Assessment will be made with the Biodex Balance System
Static Balance- Post intervention
Time frame: Assessment will be conducted immediately after the intervention
Assessment will be made with the Biodex Balance System
Gait speed- Baseline
Time frame: Assessment will be conducted before the intervention
Assessment will be made with the BTS G-Walk, (BTS SpA, Via della Croce Rossa, 11 Padova, Italy; SN: 0213-0378) during gait
Gait speed- Post intervention
Time frame: Assessment will be conducted immediately after the intervention
Assessment will be made with the BTS G-Walk, (BTS SpA, Via della Croce Rossa, 11 Padova, Italy; SN: 0213-0378) during gait
Knee strength- Baseline
Time frame: Assessment will be conducted before the intervention
Assessment will be made with an isokinetic dynamometer (Cybex Humac Norm Testing and Rehabilitation System, CSMI, USA)
Knee strength-Post intervention
Time frame: Assessment will be conducted immediately after the intervention
Assessment will be made with an isokinetic dynamometer (Cybex Humac Norm Testing and Rehabilitation System, CSMI, USA)
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 28 Dec 2023.
- Background: PubMed 31516672Daneshvar P, Ghasemi G, Zolaktaf V, Karimi MT. Comparison of the Effect of 8-Week Rebound Therapy-Based Exercise Program and Weight-Supported Exercises on the Range of Motion, Proprioception, and the Quality of Life in Patients with Parkinson's Disease. Int J Prev Med. 2019 Aug 12;10:131. doi: 10.4103/ijpvm.IJPVM_527_18. eCollection 2019.
- Derived from this study: PubMed 41592453Eldemir S, Polat EA, Gokdogan CM, Eldemir K, Guclu-Gunduz A, Yilmaz R, Akbostanci MC, Yazici G. The effect of rebound therapy in Parkinson's disease: A single-blinded randomized controlled trial. Gait Posture. 2026 Mar;125:110105. doi: 10.1016/j.gaitpost.2026.110105. Epub 2026 Jan 25.
- Individual participant dataSharing planned: No. There is no plan to make PD data but when the statistical analysis of all data is made, all results will be shared.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Rebound therapy and Exercises on a stable surface in people with Parkinson Disease, run by Gazi University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 28 Dec 2023. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Static Balance- Baseline (time frame: Assessment will be conducted before the intervention). The study lists 6 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT05855161, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 28 Dec 2023.