Sedentary BehaviorREHITNCT05875051
REHIT Versus SMIT in Sedentary Young Women
A study testing Reduced-exertion high intensity training and Short moderate intensity training in people with Sedentary Behavior, run by University of Valencia at 1 site in Spain.
Trial summary
Reduced-exertion high-intensity training (REHIT) is a novel form of exercise known for being non-classical, time-efficient, and effective on different populations. However, REHIT was scarcely tested on sedentary women with mortality risks. Read more about this study
- Who is it for?
- Ages 18 to 25 years, women only
- Conditions the study is for
- Sedentary Behavior
- What is being tested?
- Reduced-exertion high intensity training and Short moderate intensity training
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 30 participants
- Where
- 1 siteSpain
- Study dates
- 1 Dec 2021to 30 Apr 2022
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 25 years
- Women only
- No healthy volunteers
- Adult
Who may be able to join
- Women.
- Age between 18 and 25 years old.
- Those who score a low physical activity level (< 600 METS min/week) in the International Physical Activity Questionnaire-short form.
Who cannot join
- Women who suffer from musculoskeletal.
- Women who suffer from neurological diseases.
- Those who are taking medications.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effects of Reduced-exertion High-intensity Training Versus Short Moderate Intensity Training on Functional Capacity and Physical Activity Enjoyment in Sedentary Young Women A Randomized Trial
Reduced-exertion high-intensity training (REHIT) is a novel form of exercise known for being non-classical, time-efficient, and effective on different populations. However, REHIT was scarcely tested on sedentary women with mortality risks. The aim of the study is to compare the effects of REHIT versus short moderate-intensity training (SMIT) on functional capacity, resting heart rate (RHR), and activity enjoyment in sedentary young women.
Read the detailed description
The aim of the study is to compare the effects of reduced-exertion high-intensity training (REHIT) versus short moderate-intensity training (SMIT) on functional capacity, resting heart rate (RHR), and activity enjoyment in sedentary young women. Therefore, sedentary young women will be randomly allocated to either a: i) REHIT group or ii) SMIT group. Both groups will perform an intervention over 6 weeks duration for 10 minutes each session for 2 sessions/week, but with different intensities (REHIT or SMIT). Both forms of exercise will be conducted on a cycle ergometer with the subjects monitored throughout the intervention. Before and after the 3-week intervention, functional capacity (6-minute walking test) and RHR will be measured. Additionally, physical activity enjoyment (Physical Activity Enjoyment Scale) will be assessed after the intervention.
- Conditions
- Sedentary Behavior
- Being tested
- Reduced-exertion high intensity training, Short moderate intensity training
- Keywords
- High-intensity training, Moderate intensity training, Sedentary young women
- Medical subject headings
- Sedentary Behavior
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Reduced-exertion high intensity trainingOther
The intervention of the REHIT group will consist of three parts: i) 3 minutes of warm-up part at 50% of HRmax obtained in the effort test; ii) 3 min 20 sec to 3 min 40 sec of REHIT; and iii) 3 minutes of cool-down at 50% of HRmax obtained in the effort test. The REHIT part will consist of maximum cycling sprints of all-out exercise at 100% of the HRmax, increasing for up to 10 seconds, 15 seconds on week two and 20 seconds on week three. Then, 3 minutes of active rest at 50% of HRmax. Finally, 10 seconds of all-out exercise at 100% of the HRmax, rising to 15 seconds on week two and 20 seconds on week three.
Short moderate intensity trainingOther
The SMIT group will receive a short moderate-intensity training with the same warm-up and cool-down exercises as the REHIT group. In addition, the main part of the session consisted of 6 minutes of moderate intensity exercise at 60-70% HRmax obtained in the effort test. In addition, the main part of the session increases 3 min every week as 6 min for the first 2 weeks, 9 min for the 3rd and 4th weeks, and 12 min for the last two weeks.
| Study group | Role | What they receive |
|---|---|---|
| Reduced-exertion high intensity training group | Experimental | The REHIT part will consist of maximum cycling sprints of all-out exercise at 100% of the HRmax, increasing for up to 10 seconds, 15 seconds on week two and 20 seconds on week three. Receives: Other: Reduced-exertion high intensity training |
| Short moderate intensity training group | Active comparator | The SMIT part of the session will consist of 6 minutes of moderate intensity exercise at 60-70% HRmax. Receives: Other: Short moderate intensity training |
What is being measured
The primary outcome is the main question the study is designed to answer.
Functional capacity
It will be measured using the 6-minutes walking test (6MWT). Participants will be instructed to walk as quickly as possible along a 30-meter hallway for a duration of six minutes without running. Then, the distance in meters they cover will be registered. The greater the number of meters run, the better the functional capacity.
Measured: Baseline
Functional capacity
It will be measured using the 6-minutes walking test (6MWT). Participants will be instructed to walk as quickly as possible along a 30-meter hallway for a duration of six minutes without running. Then, the distance in meters they cover will be registered. The greater the number of meters run, the better the functional capacity.
Measured: After the intervention (3 weeks)
Secondary outcomes (4)
Resting heart rate
It will be measured with a patient monitor (ProAct PC-3000 Patient Monitor, Medisave, UK).
Measured: Baseline
Resting heart rate
It will be measured with a patient monitor (ProAct PC-3000 Patient Monitor, Medisave, UK).
Measured: After the intervention (3 weeks)
Physical activity enjoyment
To assess enjoyment, a modified version of the Physical Activity Enjoyment Scale (PACES) will be used. In this questionnaire, 17 items are scored on a 7-point bipolar scale, with an overall enjoyment score ranging from 17 (not enjoyable) to 68 (neutral) and 119 (enjoyable).
Measured: Baseline
Physical activity enjoyment
To assess enjoyment, a modified version of the Physical Activity Enjoyment Scale (PACES) will be used. In this questionnaire, 17 items are scored on a 7-point bipolar scale, with an overall enjoyment score ranging from 17 (not enjoyable) to 68 (neutral) and 119 (enjoyable).
Measured: After the intervention (3 weeks)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted25 May 2023
- Study start1 Dec 2021
- Primary completion30 Apr 2022
- Study completion30 Apr 2022
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (4)Papers the sponsor has linked to this study.
- Other trials for Sedentary BehaviorStudies of the same condition, open and under way.
- More trials run by University of ValenciaThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 30 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Valencia
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Elena Marques-Sule, University of Valencia
- Investigators
- Elena Marqués Sulé, PhD, Principal investigator, Univeristy of Valencia
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05875051
- Sponsor's protocol ID
- 035/3/20
- Acronym
- REHIT
- Status last verified
- May 2023
- First submitted
- 16 May 2023
- Last updated
- 25 May 2023
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Metcalfe RS, Atef H, Mackintosh K, McNarry M, Ryde G, Hill DM, Vollaard NBJ. Time-efficient and computer-guided sprint interval exercise training for improving health in the workplace: a randomised mixed-methods feasibility study in office-based employees. BMC Public Health. 2020 Mar 12;20(1):313. doi: 10.1186/s12889-020-8444-z.
PubMed 32164631Ramirez-Velez R, Hernandez-Quinones PA, Tordecilla-Sanders A, Alvarez C, Ramirez-Campillo R, Izquierdo M, Correa-Bautista JE, Garcia-Hermoso A, Garcia RG. Effectiveness of HIIT compared to moderate continuous training in improving vascular parameters in inactive adults. Lipids Health Dis. 2019 Feb 4;18(1):42. doi: 10.1186/s12944-019-0981-z.
PubMed 30717757Metcalfe RS, Tardif N, Thompson D, Vollaard NB. Changes in aerobic capacity and glycaemic control in response to reduced-exertion high-intensity interval training (REHIT) are not different between sedentary men and women. Appl Physiol Nutr Metab. 2016 Nov;41(11):1117-1123. doi: 10.1139/apnm-2016-0253. Epub 2016 Jul 7.
PubMed 27753506Bahey El-Deen HA, Atef H, Munoz-Gomez E, Moreno-Segura N, ElZalabany S, Alanazi R, Alruwili W, Alruwili S, Sultan S, Marques-Sule E. Effects of reduced-exertion high-intensity training versus short moderate-intensity continuous training on biomarkers of mortality risk in sedentary women: A randomized clinical trial. J Bodyw Mov Ther. 2025 Jun;42:710-714. doi: 10.1016/j.jbmt.2025.01.056. Epub 2025 Feb 2.
PubMed 40325745
Study at a glance
From the registry record, last updated by the sponsor on 25 May 2023. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Reduced-exertion High-intensity Training Versus Short Moderate Intensity Training on Functional Capacity and Physical Activity Enjoyment in Sedentary Young Women A Randomized Trial
- ClinicalTrials.gov ID
- NCT05875051
- Acronym / sponsor ID
- REHIT / 035/3/20
- Conditions
- Sedentary Behavior
- Keywords
- High-intensity training, Moderate intensity training, Sedentary young women
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 30 participants (actual)
- Lead sponsor
- University of ValenciaUniversity, hospital or other
- Study start
- 1 Dec 2021 (actual)
- Primary completion
- 30 Apr 2022 (actual)
- Study completion
- 30 Apr 2022 (actual)
- First posted
- 25 May 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Reduced-exertion high-intensity training (REHIT) is a novel form of exercise known for being non-classical, time-efficient, and effective on different populations. However, REHIT was scarcely tested on sedentary women with mortality risks. The aim of the study is to compare the effects of REHIT versus short moderate-intensity training (SMIT) on functional capacity, resting heart rate (RHR), and activity enjoyment in sedentary young women.
Detailed description
The aim of the study is to compare the effects of reduced-exertion high-intensity training (REHIT) versus short moderate-intensity training (SMIT) on functional capacity, resting heart rate (RHR), and activity enjoyment in sedentary young women. Therefore, sedentary young women will be randomly allocated to either a: i) REHIT group or ii) SMIT group. Both groups will perform an intervention over 6 weeks duration for 10 minutes each session for 2 sessions/week, but with different intensities (REHIT or SMIT). Both forms of exercise will be conducted on a cycle ergometer with the subjects monitored throughout the intervention. Before and after the 3-week intervention, functional capacity (6-minute walking test) and RHR will be measured. Additionally, physical activity enjoyment (Physical Activity Enjoyment Scale) will be assessed after the intervention.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Reduced-exertion high intensity training group | Experimental | Other: Reduced-exertion high intensity trainingThe REHIT part will consist of maximum cycling sprints of all-out exercise at 100% of the HRmax, increasing for up to 10 seconds, 15 seconds on week two and 20 seconds on week three. |
| Short moderate intensity training group | Active comparator | Other: Short moderate intensity trainingThe SMIT part of the session will consist of 6 minutes of moderate intensity exercise at 60-70% HRmax. |
Who may qualify
- Ages
- 18 to 25 years
- Sex
- Female only
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (3 listed)
- Women.
- Age between 18 and 25 years old.
- Those who score a low physical activity level (< 600 METS min/week) in the International Physical Activity Questionnaire-short form.
Key exclusion criteria (3 listed)
- Women who suffer from musculoskeletal.
- Women who suffer from neurological diseases.
- Those who are taking medications.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Reduced-exertion high intensity trainingThe intervention of the REHIT group will consist of three parts: i) 3 minutes of warm-up part at 50% of HRmax obtained in the effort test; ii) 3 min 20 sec to 3 min 40 sec of REHIT; and iii) 3 minutes of cool-down at 50% of HRmax obtained in the effort test. The REHIT part will consist of maximum cycling sprints of all-out exercise at 100% of the HRmax, increasing for up to 10 seconds, 15 seconds on week two and 20 seconds on week three. Then, 3 minutes of active rest at 50% of HRmax. Finally, 10 seconds of all-out exercise at 100% of the HRmax, rising to 15 seconds on week two and 20 seconds on week three. | Other | Reduced-exertion high intensity training group |
| Short moderate intensity trainingThe SMIT group will receive a short moderate-intensity training with the same warm-up and cool-down exercises as the REHIT group. In addition, the main part of the session consisted of 6 minutes of moderate intensity exercise at 60-70% HRmax obtained in the effort test. In addition, the main part of the session increases 3 min every week as 6 min for the first 2 weeks, 9 min for the 3rd and 4th weeks, and 12 min for the last two weeks. | Other | Short moderate intensity training group |
Primary outcome
Functional capacity
Time frame: Baseline
It will be measured using the 6-minutes walking test (6MWT). Participants will be instructed to walk as quickly as possible along a 30-meter hallway for a duration of six minutes without running. Then, the distance in meters they cover will be registered. The greater the number of meters run, the better the functional capacity.
Functional capacity
Time frame: After the intervention (3 weeks)
It will be measured using the 6-minutes walking test (6MWT). Participants will be instructed to walk as quickly as possible along a 30-meter hallway for a duration of six minutes without running. Then, the distance in meters they cover will be registered. The greater the number of meters run, the better the functional capacity.
4 secondary outcomes
Resting heart rate
Time frame: Baseline
Resting heart rate
Time frame: After the intervention (3 weeks)
Physical activity enjoyment
Time frame: Baseline
Physical activity enjoyment
Time frame: After the intervention (3 weeks)
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 25 May 2023.
- Background: PubMed 32164631Metcalfe RS, Atef H, Mackintosh K, McNarry M, Ryde G, Hill DM, Vollaard NBJ. Time-efficient and computer-guided sprint interval exercise training for improving health in the workplace: a randomised mixed-methods feasibility study in office-based employees. BMC Public Health. 2020 Mar 12;20(1):313. doi: 10.1186/s12889-020-8444-z.
- Background: PubMed 30717757Ramirez-Velez R, Hernandez-Quinones PA, Tordecilla-Sanders A, Alvarez C, Ramirez-Campillo R, Izquierdo M, Correa-Bautista JE, Garcia-Hermoso A, Garcia RG. Effectiveness of HIIT compared to moderate continuous training in improving vascular parameters in inactive adults. Lipids Health Dis. 2019 Feb 4;18(1):42. doi: 10.1186/s12944-019-0981-z.
- Background: PubMed 27753506Metcalfe RS, Tardif N, Thompson D, Vollaard NB. Changes in aerobic capacity and glycaemic control in response to reduced-exertion high-intensity interval training (REHIT) are not different between sedentary men and women. Appl Physiol Nutr Metab. 2016 Nov;41(11):1117-1123. doi: 10.1139/apnm-2016-0253. Epub 2016 Jul 7.
- Derived from this study: PubMed 40325745Bahey El-Deen HA, Atef H, Munoz-Gomez E, Moreno-Segura N, ElZalabany S, Alanazi R, Alruwili W, Alruwili S, Sultan S, Marques-Sule E. Effects of reduced-exertion high-intensity training versus short moderate-intensity continuous training on biomarkers of mortality risk in sedentary women: A randomized clinical trial. J Bodyw Mov Ther. 2025 Jun;42:710-714. doi: 10.1016/j.jbmt.2025.01.056. Epub 2025 Feb 2.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Elena Marqués Sulé, PhD principal investigator
Univeristy of Valencia
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Reduced-exertion high intensity training and Short moderate intensity training in people with Sedentary Behavior, run by University of Valencia at 1 site in Spain.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 25 May 2023. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Spain. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Functional capacity (time frame: Baseline). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT05875051, which also lists 4 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 25 May 2023.