Attention Deficit Disorder With HyperactivityNCT05875363
Neurodevelopmental Disorders in Youth With Criminal Behaviors
An observational study of Attention Deficit Disorder With Hyperactivity and Autistic Spectrum Disorder, run by National Taiwan University Hospital at 1 site in Taiwan.
Trial summary
1. Describe the prevalence of neurodevelopmental disorders among youth with criminal behaviors 2. Explore the relationship between specific neurodevelopmental disorders and the rates and types of crime 3. Examine the roles of psychiatric comorbidities and sociodemographic factors in juvenile criminality Read more about this study
- Who is it for?
- Ages 10 to 18 years
- Conditions the study is for
- Attention Deficit Disorder With Hyperactivity, Autistic Spectrum Disorder, Conduct Disorders in Adolescence
- What is being tested?
- collect data
- How many people
- 1,000 participants
- Where
- 1 siteTaiwan
- Study dates
- 1 Apr 2021to 31 Dec 2027
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 10 to 18 years
- All sexes
- No healthy volunteers
- Child, Adult
Study population: This retrospective study is based on the counseling registry of the Juvenile Affairs Division of Taipei City Police Department. The dataset encompasses around 1000 juvenile offenders who were actively followed up by the counselors of the division. The records include the offenders' sociodemographic data, medical history, and criminal history without person-identifiable data (i.e., name, ID).
Who may be able to join
- Juvenile offender from The Juvenile Affairs Division of Taipei City Police Department
Who cannot join
- Not Juvenile offender
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Taiwan1 site, 1 recruiting
- Recruiting
National Taiwan University Hospital
Taipei
Yi-Ling Chien, MD, PhD, +886223123456#66013, ntuh.peers@gmail.com
About this study
- Describe the prevalence of neurodevelopmental disorders among youth with criminal behaviors
- Explore the relationship between specific neurodevelopmental disorders and the rates and types of crime
- Examine the roles of psychiatric comorbidities and sociodemographic factors in juvenile criminality
- Conditions
- Attention Deficit Disorder With Hyperactivity, Autistic Spectrum Disorder, Conduct Disorders in Adolescence
- Being tested
- collect data
- Keywords
- neurodevelopmental disorder, criminality, adolescence
- Medical subject headings
- Attention Deficit Disorder with Hyperactivity, Autism Spectrum Disorder, Neurodevelopmental Disorders, Criminal Behavior
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
collect dataOther
The Juvenile Affairs Division provided the records without person-identifiable data (i.e., name, ID) to the researchers. The researchers coded the above data (i.e., the offenders' sociodemographic data, medical history, and criminal history).
Demographic characteristics were collected, which are the offenders' age, gender, occupation, education level, and residence (district). We recorded the offenders' household members (without the name or age), main caregivers (e.g., father, or mother), and the parents' socioeconomic and marital status. We also tracked whether the offenders live with family members with mental illness, whether they are from at-risk families, and whether had been victims of domestic violence. The medical history and deviant (or criminal) behaviors will be collected in the attached measure.
| Study group | Role | What they receive |
|---|---|---|
| ADHD | ADHD is among the most commonly diagnosed neurodevelopmental disorders, and the worldwide prevalence. Receives: Other: collect data | |
| ASD | Autistic spectrum disorder (ASD), characterized by overriding obsessions and difficulties in social cognition, might render the affected individuals vulnerable for becoming an offender or a victim of crime. Receives: Other: collect data | |
| Other disorders in youth: CD or substance use disorder | Conduct disorder (CD), characterized by antisocial and aggressive behavior, affects 2-2.5% of children and adolescents. CD is a risk factor for antisocial personality disorder, and despite the fact that a CD diagnosis completely relies on behavioral symptoms, research has identified neurocognitive impairments. Receives: Other: collect data |
What is being measured
The primary outcome is the main question the study is designed to answer.
Prevalence of ADHD, ASD, and other neurodevelopmental disorder in juvenile offender
Statistical analysis done by SAS (v.9.4) examine the prevalence of each neurodelopmental disorder, such as ADHD and ASD.
Measured: 3 years
Age of first criminal behavior
Based on different neurodevelopmental disorder diagnosis, determine whether the data is able to predict onset and type of criminal behaviors for each juvenile offender.
Measured: 3 years
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted25 May 2023
- Study start1 Apr 2021
- Primary completion31 Dec 2027 (estimated)
- Study completion31 Dec 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (14)Papers the sponsor has linked to this study.
- Other trials for Attention Deficit Disorder With HyperactivityStudies of the same condition, open and under way.
- More trials run by National Taiwan University HospitalThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Retrospective
- Enrolment
- 1,000 participants (estimated)
Sponsor and investigators
- Lead sponsor
- National Taiwan University Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05875363
- Sponsor's protocol ID
- 202103130RIND
- Status last verified
- Jul 2026
- First submitted
- 13 Apr 2023
- Last updated
- 31 Jul 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: The collected data only stay in Dr.Chien's lab
Publications
Moore KE, Oberleitner LMS, Zonana HV, Buchanan AW, Pittman BP, Verplaetse TL, Angarita GA, Roberts W, McKee SA. Psychiatric Disorders and Crime in the US Population: Results From the National Epidemiologic Survey on Alcohol and Related Conditions Wave III. J Clin Psychiatry. 2019 Feb 12;80(2):18m12317. doi: 10.4088/JCP.18m12317.
PubMed 30758921Lamberti JS, Katsetos V, Jacobowitz DB, Weisman RL. Psychosis, Mania and Criminal Recidivism: Associations and Implications for Prevention. Harv Rev Psychiatry. 2020 May/Jun;28(3):179-202. doi: 10.1097/HRP.0000000000000251.
PubMed 32251070Elbogen EB, Johnson SC. The intricate link between violence and mental disorder: results from the National Epidemiologic Survey on Alcohol and Related Conditions. Arch Gen Psychiatry. 2009 Feb;66(2):152-61. doi: 10.1001/archgenpsychiatry.2008.537.
PubMed 19188537Fazel S, Hayes AJ, Bartellas K, Clerici M, Trestman R. Mental health of prisoners: prevalence, adverse outcomes, and interventions. Lancet Psychiatry. 2016 Sep;3(9):871-81. doi: 10.1016/S2215-0366(16)30142-0. Epub 2016 Jul 14.
PubMed 27426440Ahonen L, Loeber R, Brent DA. The Association Between Serious Mental Health Problems and Violence: Some Common Assumptions and Misconceptions. Trauma Violence Abuse. 2019 Dec;20(5):613-625. doi: 10.1177/1524838017726423. Epub 2017 Aug 23.
PubMed 29333994Skjaervo I, Skurtveit S, Clausen T, Bukten A. Substance use pattern, self-control and social network are associated with crime in a substance-using population. Drug Alcohol Rev. 2017 Mar;36(2):245-252. doi: 10.1111/dar.12406. Epub 2016 May 4.
PubMed 27147068Mundt AP, Baranyi G. The Unhappy Mental Health Triad: Comorbid Severe Mental Illnesses, Personality Disorders, and Substance Use Disorders in Prison Populations. Front Psychiatry. 2020 Aug 14;11:804. doi: 10.3389/fpsyt.2020.00804. eCollection 2020.
PubMed 32922316Davison S, Janca A. Personality disorder and criminal behaviour: what is the nature of the relationship? Curr Opin Psychiatry. 2012 Jan;25(1):39-45. doi: 10.1097/YCO.0b013e32834d18f0.
PubMed 22156936Swanson JW, Holzer CE 3rd, Ganju VK, Jono RT. Violence and psychiatric disorder in the community: evidence from the Epidemiologic Catchment Area surveys. Hosp Community Psychiatry. 1990 Jul;41(7):761-70. doi: 10.1176/ps.41.7.761.
PubMed 2142118Fischer SN, Shinn M, Shrout P, Tsemberis S. Homelessness, mental illness, and criminal activity: examining patterns over time. Am J Community Psychol. 2008 Dec;42(3-4):251-65. doi: 10.1007/s10464-008-9210-z.
PubMed 18956238Coker KL, Smith PH, Westphal A, Zonana HV, McKee SA. Crime and psychiatric disorders among youth in the US population: an analysis of the National Comorbidity Survey-Adolescent Supplement. J Am Acad Child Adolesc Psychiatry. 2014 Aug;53(8):888-98, 898.e1-2. doi: 10.1016/j.jaac.2014.05.007. Epub 2014 Jun 12.
PubMed 25062596Moffitt TE. Adolescence-limited and life-course-persistent antisocial behavior: a developmental taxonomy. Psychol Rev. 1993 Oct;100(4):674-701.
PubMed 8255953Kalvin CB, Bierman KL. Child and adolescent risk factors that differentially predict violent versus nonviolent crime. Aggress Behav. 2017 Nov;43(6):568-577. doi: 10.1002/ab.21715. Epub 2017 Jun 8.
PubMed 28597509Costello EJ, Maughan B. Annual research review: Optimal outcomes of child and adolescent mental illness. J Child Psychol Psychiatry. 2015 Mar;56(3):324-41. doi: 10.1111/jcpp.12371. Epub 2014 Dec 12.
PubMed 25496295
Study at a glance
From the registry record, last updated by the sponsor on 31 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Neurodevelopmental Disorders in Youth With Criminal Behaviors
- ClinicalTrials.gov ID
- NCT05875363
- Acronym / sponsor ID
- 202103130RIND
- Conditions
- Attention Deficit Disorder With Hyperactivity, Autistic Spectrum Disorder, Conduct Disorders in Adolescence
- Keywords
- neurodevelopmental disorder, criminality, adolescence
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 1,000 participants (estimated)
- Lead sponsor
- National Taiwan University HospitalUniversity, hospital or other
- Study start
- 1 Apr 2021 (actual)
- Primary completion
- 31 Dec 2027 (estimated)
- Study completion
- 31 Dec 2027 (estimated)
- First posted
- 25 May 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
- Describe the prevalence of neurodevelopmental disorders among youth with criminal behaviors
- Explore the relationship between specific neurodevelopmental disorders and the rates and types of crime
- Examine the roles of psychiatric comorbidities and sociodemographic factors in juvenile criminality
Study design
- Observational model
- Case only
- Time perspective
- Retrospective
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| ADHD | – | Other: collect dataADHD is among the most commonly diagnosed neurodevelopmental disorders, and the worldwide prevalence. |
| ASD | – | Other: collect dataAutistic spectrum disorder (ASD), characterized by overriding obsessions and difficulties in social cognition, might render the affected individuals vulnerable for becoming an offender or a victim of crime. |
| Other disorders in youth: CD or substance use disorder | – | Other: collect dataConduct disorder (CD), characterized by antisocial and aggressive behavior, affects 2-2.5% of children and adolescents. CD is a risk factor for antisocial personality disorder, and despite the fact that a CD diagnosis completely relies on behavioral symptoms, research has identified neurocognitive impairments. |
Who may qualify
- Ages
- 10 to 18 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult
- Study population
- This retrospective study is based on the counseling registry of the Juvenile Affairs Division of Taipei City Police Department. The dataset encompasses around 1000 juvenile offenders who were actively followed up by the counselors of the division. The records include the offenders' sociodemographic data, medical history, and criminal history without person-identifiable data (i.e., name, ID).
Key inclusion criteria (1 listed)
- Juvenile offender from The Juvenile Affairs Division of Taipei City Police Department
Key exclusion criteria (1 listed)
- Not Juvenile offender
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| collect dataThe Juvenile Affairs Division provided the records without person-identifiable data (i.e., name, ID) to the researchers. The researchers coded the above data (i.e., the offenders' sociodemographic data, medical history, and criminal history). Demographic characteristics were collected, which are the offenders' age, gender, occupation, education level, and residence (district). We recorded the offenders' household members (without the name or age), main caregivers (e.g., father, or mother), and the parents' socioeconomic and marital status. We also tracked whether the offenders live with family members with mental illness, whether they are from at-risk families, and whether had been victims of domestic violence. The medical history and deviant (or criminal) behaviors will be collected in the attached measure. | Other | ADHD, ASD, Other disorders in youth: CD or substance use disorder |
Primary outcome
Prevalence of ADHD, ASD, and other neurodevelopmental disorder in juvenile offender
Time frame: 3 years
Statistical analysis done by SAS (v.9.4) examine the prevalence of each neurodelopmental disorder, such as ADHD and ASD.
Age of first criminal behavior
Time frame: 3 years
Based on different neurodevelopmental disorder diagnosis, determine whether the data is able to predict onset and type of criminal behaviors for each juvenile offender.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 31 Jul 2026.
- Background: PubMed 30758921Moore KE, Oberleitner LMS, Zonana HV, Buchanan AW, Pittman BP, Verplaetse TL, Angarita GA, Roberts W, McKee SA. Psychiatric Disorders and Crime in the US Population: Results From the National Epidemiologic Survey on Alcohol and Related Conditions Wave III. J Clin Psychiatry. 2019 Feb 12;80(2):18m12317. doi: 10.4088/JCP.18m12317.
- Background: PubMed 32251070Lamberti JS, Katsetos V, Jacobowitz DB, Weisman RL. Psychosis, Mania and Criminal Recidivism: Associations and Implications for Prevention. Harv Rev Psychiatry. 2020 May/Jun;28(3):179-202. doi: 10.1097/HRP.0000000000000251.
- Background: PubMed 19188537Elbogen EB, Johnson SC. The intricate link between violence and mental disorder: results from the National Epidemiologic Survey on Alcohol and Related Conditions. Arch Gen Psychiatry. 2009 Feb;66(2):152-61. doi: 10.1001/archgenpsychiatry.2008.537.
- Background: PubMed 27426440Fazel S, Hayes AJ, Bartellas K, Clerici M, Trestman R. Mental health of prisoners: prevalence, adverse outcomes, and interventions. Lancet Psychiatry. 2016 Sep;3(9):871-81. doi: 10.1016/S2215-0366(16)30142-0. Epub 2016 Jul 14.
- Background: PubMed 29333994Ahonen L, Loeber R, Brent DA. The Association Between Serious Mental Health Problems and Violence: Some Common Assumptions and Misconceptions. Trauma Violence Abuse. 2019 Dec;20(5):613-625. doi: 10.1177/1524838017726423. Epub 2017 Aug 23.
- Background: PubMed 27147068Skjaervo I, Skurtveit S, Clausen T, Bukten A. Substance use pattern, self-control and social network are associated with crime in a substance-using population. Drug Alcohol Rev. 2017 Mar;36(2):245-252. doi: 10.1111/dar.12406. Epub 2016 May 4.
- Background: PubMed 32922316Mundt AP, Baranyi G. The Unhappy Mental Health Triad: Comorbid Severe Mental Illnesses, Personality Disorders, and Substance Use Disorders in Prison Populations. Front Psychiatry. 2020 Aug 14;11:804. doi: 10.3389/fpsyt.2020.00804. eCollection 2020.
- Background: PubMed 22156936Davison S, Janca A. Personality disorder and criminal behaviour: what is the nature of the relationship? Curr Opin Psychiatry. 2012 Jan;25(1):39-45. doi: 10.1097/YCO.0b013e32834d18f0.
- Background: PubMed 2142118Swanson JW, Holzer CE 3rd, Ganju VK, Jono RT. Violence and psychiatric disorder in the community: evidence from the Epidemiologic Catchment Area surveys. Hosp Community Psychiatry. 1990 Jul;41(7):761-70. doi: 10.1176/ps.41.7.761.
- Background: PubMed 18956238Fischer SN, Shinn M, Shrout P, Tsemberis S. Homelessness, mental illness, and criminal activity: examining patterns over time. Am J Community Psychol. 2008 Dec;42(3-4):251-65. doi: 10.1007/s10464-008-9210-z.
- Background: PubMed 25062596Coker KL, Smith PH, Westphal A, Zonana HV, McKee SA. Crime and psychiatric disorders among youth in the US population: an analysis of the National Comorbidity Survey-Adolescent Supplement. J Am Acad Child Adolesc Psychiatry. 2014 Aug;53(8):888-98, 898.e1-2. doi: 10.1016/j.jaac.2014.05.007. Epub 2014 Jun 12.
- Background: PubMed 8255953Moffitt TE. Adolescence-limited and life-course-persistent antisocial behavior: a developmental taxonomy. Psychol Rev. 1993 Oct;100(4):674-701.
- Individual participant dataSharing planned: No. The collected data only stay in Dr.Chien's lab
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Attention Deficit Disorder With Hyperactivity and Autistic Spectrum Disorder, run by National Taiwan University Hospital at 1 site in Taiwan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 31 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Taiwan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Yi-Ling Chien (+886223123456#66013, chienyiling@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Prevalence of ADHD, ASD, and other neurodevelopmental disorder in juvenile offender (time frame: 3 years). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT05875363, which also lists 14 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 31 Jul 2026.