COPD ExacerbationTELE-TOCNCT05897125
Telehealth Education Leveraging Electronic Transitions Of Care for COPD Patients
A study testing Virtual at Home Medication Reconciliation Visit(s), Virtual At Home Medication Education Visit(s) and COPD advanced practice nurse Inpatient Consult in people with COPD Exacerbation and Care Transitions, run by University of Chicago at 1 site in United States.
Trial summary
Transitions of Care (TOC) between hospital, ambulatory, and home settings for high-risk, frequently hospitalized adults with chronic diseases, such as chronic obstructive pulmonary disease (COPD) are complex, costly, and vulnerable to safety threats and poor health outcomes. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- COPD Exacerbation, Care Transitions
- What is being tested?
- Virtual at Home Medication Reconciliation Visit(s), Virtual At Home Medication Education Visit(s) and COPD advanced practice nurse Inpatient Consult
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 218 participants
- Where
- 1 siteUnited States
- Study dates
- 19 Feb 2025to 31 Dec 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Adults 18 years or older
- Admitted to the hospital on a general inpatient ward with a COPD Exacerbation
- Enrolled/seen by our COPD Hospital Readmission Reduction Program
Who cannot join
- Patients younger than 18 years of age
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
About this study
Official title: TELE-TOC: Telehealth Education Leveraging Electronic Transitions Of Care for COPD Patients
Transitions of Care (TOC) between hospital, ambulatory, and home settings for high-risk, frequently hospitalized adults with chronic diseases, such as chronic obstructive pulmonary disease (COPD) are complex, costly, and vulnerable to safety threats and poor health outcomes. One potential solution to address this gap in care is the Transitional Care Model (TCM), which utilizes a patient-centered approach with in-home interventions; since in-person in-home visits are costly, using innovative telehealth, such as virtual visits via teleconferencing may be just as effective with greater feasibility, scalability, and sustainability, particularly in the post-COVID-19 era as has been seen the rapid expansion of these technologies. With a transdisciplinary team of experts from cognitive science, care transitions/handoffs, human factors engineering, design, implementation science, and health services research, the study team proposes to implement and evaluate via a randomized clinical trial the "TELE-TOC: Telehealth Education: Leveraging Electronic Transitions Of Care for COPD patients," intervention which includes a virtual visit, pharmacy-based, in-home intervention for COPD patients to improve medication use and patient outcomes among a population at high risk for readmission and medication safety events.
Read the detailed description
Transitions of Care (TOC) for high-risk, frequently hospitalized adults with chronic diseases are complex, costly, and vulnerable to safety threats and poor health outcomes. Communication breakdowns, information lapses, and IT-induced unintended consequences can result in poor follow-up and medication non-adherence, both of which contribute to preventable readmissions or emergency room (ER) visits. The Transitional Care Model (TCM) aims to reduce such risks through a holistic, collaborative, patient-centered approach with in-home interventions. Prior to the coronavirus disease 2019 (COVID-19) pandemic, most in- home interventions relied on in-person visits, which can be cost-prohibitive and unsustainable. One potential sustainable and scalable solution is to use telehealth for in-home virtual visits; however, use of telehealth for post-discharge TOC interventions has not been routinely implemented. In the post-COVID-19 era, given the rapid expansion of telehealth, hospitals are well-positioned to initiate this virtual care. In-home virtual visits may be particularly promising for patients with chronic obstructive pulmonary disease (COPD), who are often hospitalized, have multiple comorbidities, and require intensive medication teaching due to rampant inhaler misuse. COPD affects more than 16 million US adults, many of whom are older, contribute ~$50 billion to healthcare costs annually, experience high rates of acute care revisits, often due to care coordination failures. For this reason, Medicare's Hospital Readmission Reduction Program (HRRP) aims to incentivize hospitals to implement TOC programs for increased quality and value of care for COPD patients. However, currently, such programs fall short of aligning with the full TCM. In-home interventions may be particularly salient for improving medication skills and outcomes for patients with COPD given rampant inhaler misuses, the effectiveness of in- hospital inhaler education, and evidence showing the need for inhaler education reinforcement post discharge. Thus, our trans-disciplinary team proposes to implement and evaluate "TELE-TOC: Telehealth Education: Leveraging Electronic Transitions Of Care for COPD patients," which seeks to integrate virtual, pharmacy-based, in-home visits for COPD patients within our hospital's existing COPD HRRP. The central hypotheses are that virtual visits with pharmacists will be feasible to implement and will result in improved medication use and outcomes among COPD patients at high risk for readmission. The investigator aims to iteratively design TELE-TOC using participatory study design and stakeholder input. The study team will then test the effectiveness of adding TELE-TOC virtual visits in a randomized controlled trial among COPD patients enrolled in the HRRP program. Lastly, the study team will develop a plan for a dissemination strategy and roadmap with national stakeholders to facilitate wide scale adoption of TELE-TOC nation wide.
- Conditions
- COPD Exacerbation, Care Transitions
- Being tested
- Virtual at Home Medication Reconciliation Visit(s), Virtual At Home Medication Education Visit(s), COPD advanced practice nurse Inpatient Consult, Inpatient Medication Reconciliation, Post-discharge nurse 48 hour phone follow-up call
- Keywords
- Medication education, Medication reconciliation, Medication Adherence
- Medical subject headings
- Medication Adherence
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Virtual at Home Medication Reconciliation Visit(s)Other
Also called Virtual At Home Medication Reconciliation
Patients will have their medications reviewed by the TELE-TOC interventionalist, a member of the pharmacy team (anticipated)
Virtual At Home Medication Education Visit(s)Behavioural
Also called Virtual At Home Inhaler Education
Patients will be provided with inhaler education by the TELE-TOC interventionalist, a member of the pharmacy team (anticipated)
COPD advanced practice nurse Inpatient ConsultOther
Also called Inpatient consult
Patients will receive a COPD consult by an advanced practice nurse as part of standard of care
Inpatient Medication ReconciliationOther
Patients will have their medications reviewed by member(s) of the clinical care team as part of standard of care
Post-discharge nurse 48 hour phone follow-up callOther
Patients will receive a post-discharge nurse 48 hour phone follow-up call as part of standard of care
Post-discharge follow-up advanced practice nurse outpatient visitOther
Patients will be scheduled for a 1-2 week post-discharge visit with the COPD advanced practice nurse as part of standard of care
| Study group | Role | What they receive |
|---|---|---|
| TELE-TOC plus Usual Care | Experimental | Patients randomized to this arm will receive the TELE-TOC intervention as well as the standard COPD care via the institution's COPD readmission reduction program. Receives: Other: Virtual at Home Medication Reconciliation Visit(s); Behavioral: Virtual At Home Medication Education Visit(s); Other: COPD advanced practice nurse Inpatient Consult; Other: Inpatient Medication Reconciliation; Other: Post-discharge nurse 48 hour phone follow-up call; Other: Post-discharge follow-up advanced practice nurse outpatient visit |
| Usual Care | Active comparator | Patients randomized to this arm will receive standard COPD care via the institution's COPD readmission reduction program. Receives: Other: COPD advanced practice nurse Inpatient Consult; Other: Inpatient Medication Reconciliation; Other: Post-discharge nurse 48 hour phone follow-up call; Other: Post-discharge follow-up advanced practice nurse outpatient visit |
What is being measured
The primary outcome is the main question the study is designed to answer.
Correct inhaler technique 30 days post discharge
Correct inhaler technique within 30 days post-discharge compared to baseline technique in hospital based on standardized checklists (<75% correct steps = misuse)
Measured: 30 days post discharge
Reach of the TELE-TOC intervention
Proportion of patients receiving at home inhaler education within 1-2 weeks post discharge
Measured: 1-2 weeks post discharge
Secondary outcomes (6)
30 day revisits
proportion of patients with any emergency department visit and/or re-hospitalization within 30 days of index admission
Measured: 30 -days
90 day revisits
proportion of patients with any emergency department visit and/or re-hospitalization within 90 days of index admission
Measured: 90 -days
180 day revisits
proportion of patients with any emergency department visit and/or re-hospitalization within 180 days of index admission
Measured: 180 -days
Medication errors
Proportion of patients with medication errors at TELE-TOC visit medication reconciliation
Measured: Within 30 days
COPD Symptoms option 1
Evaluation of COPD symptoms using COPD Assessment Test (CAT)
Measured: Within 30 days
COPD Symptoms option 2
Evaluation of COPD symptoms using the modified medical Research Council Scale (mmRC) [Scale = 0 to 4; 0 (better) = Breathlessness only on strenuous exercise; 4 (worse)= too breathless to leave the house or breathless when dressing or undressing]
Measured: Within 30 days
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted9 Jun 2023
- Study start19 Feb 2025
- Primary completion31 Aug 2026 (estimated)
- Study completion31 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (6)Papers the sponsor has linked to this study.
- Other trials for COPD ExacerbationStudies of the same condition, open and under way.
- More trials run by University of ChicagoThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- 1:1 randomization
- Masking
- Single blind
- Who is masked
- Investigator
- Enrolment
- 218 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Chicago
- Sponsor type
- University, hospital or other
- Collaborators
- Agency for Healthcare Research and Quality (AHRQ), Washington University School of Medicine, Society of Hospital Medicine, COPD Foundation, Hospital Medicine Reengineering Network (HOMERuN), The American Telemedicine Association
- Responsible party
- Sponsor
- Investigators
- Valerie G Press, MD, MPH, Principal investigator, University of Chicago
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05897125
- Sponsor's protocol ID
- IRB21-1325
- Acronym
- TELE-TOC
- Status last verified
- Jan 2026
- First submitted
- 10 May 2023
- Last updated
- 14 Jan 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: De-identified participant data, associated documentation, and study materials will be made available to other researchers following publication of the primary results. Data will be shared in accordance with institutional policies and data use agreements.
Publications
Naylor MD, Aiken LH, Kurtzman ET, Olds DM, Hirschman KB. The care span: The importance of transitional care in achieving health reform. Health Aff (Millwood). 2011 Apr;30(4):746-54. doi: 10.1377/hlthaff.2011.0041.
PubMed 21471497Locke ER, Thomas RM, Woo DM, Nguyen EHK, Tamanaha BK, Press VG, Reiber GE, Kaboli PJ, Fan VS. Using Video Telehealth to Facilitate Inhaler Training in Rural Patients with Obstructive Lung Disease. Telemed J E Health. 2019 Mar;25(3):230-236. doi: 10.1089/tmj.2017.0330. Epub 2018 Jul 17.
PubMed 30016216Thomas RM, Locke ER, Woo DM, Nguyen EHK, Press VG, Layouni TA, Trittschuh EH, Reiber GE, Fan VS. Inhaler Training Delivered by Internet-Based Home Videoconferencing Improves Technique and Quality of Life. Respir Care. 2017 Nov;62(11):1412-1422. doi: 10.4187/respcare.05445. Epub 2017 Jul 18.
PubMed 28720676Jencks SF, Williams MV, Coleman EA. Rehospitalizations among patients in the Medicare fee-for-service program. N Engl J Med. 2009 Apr 2;360(14):1418-28. doi: 10.1056/NEJMsa0803563.
PubMed 19339721Press VG, Au DH, Bourbeau J, Dransfield MT, Gershon AS, Krishnan JA, Mularski RA, Sciurba FC, Sullivan J, Feemster LC. Reducing Chronic Obstructive Pulmonary Disease Hospital Readmissions. An Official American Thoracic Society Workshop Report. Ann Am Thorac Soc. 2019 Feb;16(2):161-170. doi: 10.1513/AnnalsATS.201811-755WS.
PubMed 30707066Ramadurai D, Lee CT, Traeger L, Pucci G, Jackson-Sagredo A, Shah S, Abraham J, Arora VM, Press VG. Telehealth Education Leveraging Electronic Transitions Of Care for COPD Patients (TELE-TOC): a study protocol for a type II hybrid effectiveness-implementation randomised, pragmatic clinical trial of a pharmacist-led intervention. BMJ Open. 2025 Nov 4;15(11):e105521. doi: 10.1136/bmjopen-2025-105521.
PubMed 41193196
Study at a glance
From the registry record, last updated by the sponsor on 14 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- TELE-TOC: Telehealth Education Leveraging Electronic Transitions Of Care for COPD Patients
- ClinicalTrials.gov ID
- NCT05897125
- Acronym / sponsor ID
- TELE-TOC / IRB21-1325
- Conditions
- COPD Exacerbation, Care Transitions
- Keywords
- Medication education, Medication reconciliation, Medication Adherence
- Study type
- Interventional
- Recruitment status
- Enrolling by invitation
- Enrolment
- 218 participants (estimated)
- Lead sponsor
- University of ChicagoUniversity, hospital or other
- Collaborators
- Agency for Healthcare Research and Quality (AHRQ), Washington University School of Medicine, Society of Hospital Medicine, COPD Foundation, Hospital Medicine Reengineering Network (HOMERuN), The American Telemedicine Association
- Study start
- 19 Feb 2025 (actual)
- Primary completion
- 31 Aug 2026 (estimated)
- Study completion
- 31 Dec 2026 (estimated)
- First posted
- 9 Jun 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Transitions of Care (TOC) between hospital, ambulatory, and home settings for high-risk, frequently hospitalized adults with chronic diseases, such as chronic obstructive pulmonary disease (COPD) are complex, costly, and vulnerable to safety threats and poor health outcomes. One potential solution to address this gap in care is the Transitional Care Model (TCM), which utilizes a patient-centered approach with in-home interventions; since in-person in-home visits are costly, using innovative telehealth, such as virtual visits via teleconferencing may be just as effective with greater feasibility, scalability, and sustainability, particularly in the post-COVID-19 era as has been seen the rapid expansion of these technologies. With a transdisciplinary team of experts from cognitive science, care transitions/handoffs, human factors engineering, design, implementation science, and health services research, the study team proposes to implement and evaluate via a randomized clinical trial the "TELE-TOC: Telehealth Education: Leveraging Electronic Transitions Of Care for COPD patients," intervention which includes a virtual visit, pharmacy-based, in-home intervention for COPD patients to improve medication use and patient outcomes among a population at high risk for readmission and medication safety events.
Detailed description
Transitions of Care (TOC) for high-risk, frequently hospitalized adults with chronic diseases are complex, costly, and vulnerable to safety threats and poor health outcomes. Communication breakdowns, information lapses, and IT-induced unintended consequences can result in poor follow-up and medication non-adherence, both of which contribute to preventable readmissions or emergency room (ER) visits. The Transitional Care Model (TCM) aims to reduce such risks through a holistic, collaborative, patient-centered approach with in-home interventions. Prior to the coronavirus disease 2019 (COVID-19) pandemic, most in- home interventions relied on in-person visits, which can be cost-prohibitive and unsustainable. One potential sustainable and scalable solution is to use telehealth for in-home virtual visits; however, use of telehealth for post-discharge TOC interventions has not been routinely implemented. In the post-COVID-19 era, given the rapid expansion of telehealth, hospitals are well-positioned to initiate this virtual care. In-home virtual visits may be particularly promising for patients with chronic obstructive pulmonary disease (COPD), who are often hospitalized, have multiple comorbidities, and require intensive medication teaching due to rampant inhaler misuse. COPD affects more than 16 million US adults, many of whom are older, contribute ~$50 billion to healthcare costs annually, experience high rates of acute care revisits, often due to care coordination failures. For this reason, Medicare's Hospital Readmission Reduction Program (HRRP) aims to incentivize hospitals to implement TOC programs for increased quality and value of care for COPD patients. However, currently, such programs fall short of aligning with the full TCM. In-home interventions may be particularly salient for improving medication skills and outcomes for patients with COPD given rampant inhaler misuses, the effectiveness of in- hospital inhaler education, and evidence showing the need for inhaler education reinforcement post discharge. Thus, our trans-disciplinary team proposes to implement and evaluate "TELE-TOC: Telehealth Education: Leveraging Electronic Transitions Of Care for COPD patients," which seeks to integrate virtual, pharmacy-based, in-home visits for COPD patients within our hospital's existing COPD HRRP. The central hypotheses are that virtual visits with pharmacists will be feasible to implement and will result in improved medication use and outcomes among COPD patients at high risk for readmission. The investigator aims to iteratively design TELE-TOC using participatory study design and stakeholder input. The study team will then test the effectiveness of adding TELE-TOC virtual visits in a randomized controlled trial among COPD patients enrolled in the HRRP program. Lastly, the study team will develop a plan for a dissemination strategy and roadmap with national stakeholders to facilitate wide scale adoption of TELE-TOC nation wide.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (investigator)
- Number of arms
- 2
- Model description
- 1:1 randomization
| Arm | Type | Receives |
|---|---|---|
| TELE-TOC plus Usual Care | Experimental | Other: Virtual at Home Medication Reconciliation Visit(s), Behavioral: Virtual At Home Medication Education Visit(s), Other: COPD advanced practice nurse Inpatient Consult, Other: Inpatient Medication Reconciliation, Other: Post-discharge nurse 48 hour phone follow-up call, Other: Post-discharge follow-up advanced practice nurse outpatient visitPatients randomized to this arm will receive the TELE-TOC intervention as well as the standard COPD care via the institution's COPD readmission reduction program. |
| Usual Care | Active comparator | Other: COPD advanced practice nurse Inpatient Consult, Other: Inpatient Medication Reconciliation, Other: Post-discharge nurse 48 hour phone follow-up call, Other: Post-discharge follow-up advanced practice nurse outpatient visitPatients randomized to this arm will receive standard COPD care via the institution's COPD readmission reduction program. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Adults 18 years or older
- Admitted to the hospital on a general inpatient ward with a COPD Exacerbation
- Enrolled/seen by our COPD Hospital Readmission Reduction Program
Key exclusion criteria (1 listed)
- Patients younger than 18 years of age
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Virtual at Home Medication Reconciliation Visit(s)Also: Virtual At Home Medication ReconciliationPatients will have their medications reviewed by the TELE-TOC interventionalist, a member of the pharmacy team (anticipated) | Other | TELE-TOC plus Usual Care |
| Virtual At Home Medication Education Visit(s)Also: Virtual At Home Inhaler EducationPatients will be provided with inhaler education by the TELE-TOC interventionalist, a member of the pharmacy team (anticipated) | Behavioural | TELE-TOC plus Usual Care |
| COPD advanced practice nurse Inpatient ConsultAlso: Inpatient consultPatients will receive a COPD consult by an advanced practice nurse as part of standard of care | Other | TELE-TOC plus Usual Care, Usual Care |
| Inpatient Medication ReconciliationPatients will have their medications reviewed by member(s) of the clinical care team as part of standard of care | Other | TELE-TOC plus Usual Care, Usual Care |
| Post-discharge nurse 48 hour phone follow-up callPatients will receive a post-discharge nurse 48 hour phone follow-up call as part of standard of care | Other | TELE-TOC plus Usual Care, Usual Care |
| Post-discharge follow-up advanced practice nurse outpatient visitPatients will be scheduled for a 1-2 week post-discharge visit with the COPD advanced practice nurse as part of standard of care | Other | TELE-TOC plus Usual Care, Usual Care |
Primary outcome
Correct inhaler technique 30 days post discharge
Time frame: 30 days post discharge
Correct inhaler technique within 30 days post-discharge compared to baseline technique in hospital based on standardized checklists (<75% correct steps = misuse)
Reach of the TELE-TOC intervention
Time frame: 1-2 weeks post discharge
Proportion of patients receiving at home inhaler education within 1-2 weeks post discharge
6 secondary outcomes
30 day revisits
Time frame: 30 -days
90 day revisits
Time frame: 90 -days
180 day revisits
Time frame: 180 -days
Medication errors
Time frame: Within 30 days
COPD Symptoms option 1
Time frame: Within 30 days
COPD Symptoms option 2
Time frame: Within 30 days
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 14 Jan 2026.
- Background: PubMed 21471497Naylor MD, Aiken LH, Kurtzman ET, Olds DM, Hirschman KB. The care span: The importance of transitional care in achieving health reform. Health Aff (Millwood). 2011 Apr;30(4):746-54. doi: 10.1377/hlthaff.2011.0041.
- Background: PubMed 30016216Locke ER, Thomas RM, Woo DM, Nguyen EHK, Tamanaha BK, Press VG, Reiber GE, Kaboli PJ, Fan VS. Using Video Telehealth to Facilitate Inhaler Training in Rural Patients with Obstructive Lung Disease. Telemed J E Health. 2019 Mar;25(3):230-236. doi: 10.1089/tmj.2017.0330. Epub 2018 Jul 17.
- Background: PubMed 28720676Thomas RM, Locke ER, Woo DM, Nguyen EHK, Press VG, Layouni TA, Trittschuh EH, Reiber GE, Fan VS. Inhaler Training Delivered by Internet-Based Home Videoconferencing Improves Technique and Quality of Life. Respir Care. 2017 Nov;62(11):1412-1422. doi: 10.4187/respcare.05445. Epub 2017 Jul 18.
- Background: PubMed 19339721Jencks SF, Williams MV, Coleman EA. Rehospitalizations among patients in the Medicare fee-for-service program. N Engl J Med. 2009 Apr 2;360(14):1418-28. doi: 10.1056/NEJMsa0803563.
- Background: PubMed 30707066Press VG, Au DH, Bourbeau J, Dransfield MT, Gershon AS, Krishnan JA, Mularski RA, Sciurba FC, Sullivan J, Feemster LC. Reducing Chronic Obstructive Pulmonary Disease Hospital Readmissions. An Official American Thoracic Society Workshop Report. Ann Am Thorac Soc. 2019 Feb;16(2):161-170. doi: 10.1513/AnnalsATS.201811-755WS.
- Derived from this study: PubMed 41193196Ramadurai D, Lee CT, Traeger L, Pucci G, Jackson-Sagredo A, Shah S, Abraham J, Arora VM, Press VG. Telehealth Education Leveraging Electronic Transitions Of Care for COPD Patients (TELE-TOC): a study protocol for a type II hybrid effectiveness-implementation randomised, pragmatic clinical trial of a pharmacist-led intervention. BMJ Open. 2025 Nov 4;15(11):e105521. doi: 10.1136/bmjopen-2025-105521.
- Contextual Frameworks for Research on the Implementation of Complex System InterventionsLink provided by the sponsor.
- Centers for Medicare and Medicaid Services Hospital Readmission Reduction Program (HRRP)Link provided by the sponsor.
- Individual participant dataSharing planned: Yes. De-identified participant data, associated documentation, and study materials will be made available to other researchers following publication of the primary results. Data will be shared in accordance with institutional policies and data use agreements.
Related trials for COPD Exacerbation
Active, not recruiting
Influence of FreeO2 on Percentage of Time Within Oxygen Saturation Target Using Noninvasive Ventilation (NIV) and Continuous Positive Airway Pressure (CPAP) for Patients Admitted for AECOPD or Bariatric Surgery
COPD Exacerbation, Oxygen Toxicity
Active, not recruiting
FreeDom: Innovative Strategy for the Management of COPD Exacerbations
Oxygen Deficiency, COPD Exacerbation
RecruitingPhase 2
Rademikibart IV for Acute Asthma and COPD Exacerbation
Asthma Acute, COPD Exacerbation Acute
Not yet recruitingPhase 1
Investigating Senolytic Properties in Pulmonary Rehabilitation and Metformin in COPD Exacerbations
Chronic Obstructive Pulmonary Disease (COPD)
RecruitingObservational study
Swiss Chronic Obstructive Pulmonary Disease (COPD) Management Cohort
Chronic Obstructive Pulmonary Disease, COPD Exacerbation
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Valerie G Press, MD, MPH principal investigator
University of Chicago
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Virtual at Home Medication Reconciliation Visit(s), Virtual At Home Medication Education Visit(s) and COPD advanced practice nurse Inpatient Consult in people with COPD Exacerbation and Care Transitions, run by University of Chicago at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: enrolling by invitation, as of the sponsor's last update on 14 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Correct inhaler technique 30 days post discharge (time frame: 30 days post discharge). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT05897125, which also lists 6 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 Jan 2026.