SuicideNCT05900700

Digital Youth-Nominated Support Team (YST) Program

A study testing eYST website in people with Suicide, run by University of Michigan at 1 site in United States.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Trial summary

The Electronic Youth-Nominated Support Team (eYST), is experimental. The purpose of this study is to get feedback from users about eYST. Another purpose of this study is to learn how well eYST helps youth. Read more about this study

Who is it for?: Ages 13 to 17 years
Conditions the study is for: Suicide
What is being tested?: eYST website
Type of treatment: Lifestyle or therapy programme
Could I receive a placebo?: No, everyone receives an active treatment
How many people: 75 participants
Where: 1 siteUnited States
Study dates: 27 Nov 2023to 30 Sep 2024
Phase: Interventional
Are there results?: Yes, posted in the registrySummary in the doctors' view

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

Ages 13 to 17 years
All sexes
No healthy volunteers
Child

Who may be able to join

Inpatient psychiatric patients who have attempted suicide or have documented Suicide ideation (SI) and a plan to harm themselves at admission.
Understand written and spoken English.
Own a smartphone or mobile phone.
Willing and able to complete enrollment procedures.
Parent or guardian and youth able to understand the nature of the study and provide written informed consent and assent for youth
Patients who are able to provide at least one verifiable contact for emergency or tracking purposes.

Who cannot join

Patients with active psychosis.
Patients experiencing substance withdrawal.
Currently enrolled in other treatment studies for the symptoms and behaviors targeted.
Patient unwilling or unable to wear a mask during in person study procedures, if mandated due to current COVID/health safety guidelines.
Patients who in the judgment of the investigator would have an unfavorable risk or benefit profile with respect to eYST.
Any other psychiatric or medical condition or custody arrangement that in the investigators' opinion would preclude informed consent or assent or participation in the trial.

Trial locations and contacts

1 site in 1 country.

United States1 site

Michigan Medicine
Ann Arbor, Michigan, 48109

Other trials in United States

About this study

Official title: An Open-Label Study of the Feasibility and Usability of a Digital Psychoeducational Social Network Intervention for Suicidal Adolescents

Read the detailed description

Assessment data from multiple stakeholders (i.e., youth, parents, and support adults) will be collected at baseline, 4 weeks, 8 weeks, and 12 weeks via self-report and semi-structured interviews.

A request to extend the record's NIH results reporting deadline to November 1, 2025 was submitted in a timely manner prior to October-November 2025 government shutdown. This request was approved retroactively once the shutdown ended on November 12. During the shutdown, the record was locked and could not be edited by the Responsible Party. Results were submitted as soon as possible upon the unlocking of the record.

Conditions: Suicide
Being tested: eYST website
Keywords: Social network, Website
Medical subject headings: Suicide

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

eYST websiteBehavioural
The website is a psychoeducational, social support program for adolescents at risk for suicide

Study groups in NCT05900700
Study group	Role	What they receive
eYST website	Experimental	Not described Receives: Behavioral: eYST website

What is being measured

The primary outcome is the main question the study is designed to answer.

System Usability Scale (SUS) Score - Youth Participants
10-item measure. Scores ranged from 0 to 100. The researchers calculated the mean score. A mean score of 68 was the minimal indicator of usability. Results reflect data from Youth Participants.
Measured: At 4 Weeks
System Usability Scale (SUS) Score - Adult Caregiver Participants
10-item measure. Scores ranged from 0 to 100. The researchers calculated the mean score. A mean score of 68 was the minimal indicator of usability. Results reflect data from Adult Caregiver Participants.
Measured: At 4 Weeks
System Usability Scale (SUS) Score - Adult Support Participants
10-item measure. Scores ranged from 0 to 100. The researchers calculated the mean score. A mean score of 68 was the minimal indicator of usability. Results reflect data from Adult Support Participants.
Measured: At 8 Weeks
Frequency of Use of App - Youth Participants
Website usage metrics were captured by counting the number of website log-ins by Youth (adolescent) Participants.
Measured: Weeks 1, 4, 8, and 12
Frequency of Use of App - Adult Caregiver Participants
Website usage metrics were captured by counting the number of website log-ins by parents/caregivers.
Measured: Weeks 1, 4, 8, and 12
Frequency of Use of App - Adult Support Participants
Website usage metrics were captured by counting the number of website log-ins by supporting adults.
Measured: Week 1, 4, 8, 12
Duration of Use of App - Youth Participants
Website usage metrics were captured by measuring the duration of website use by adolescents.
Measured: Weeks 1, 4, 8, and 12
Duration of Use of App - Adult Caregiver Participants
Website usage metrics were captured by measuring the duration of website use by parents/caregivers.
Measured: Weeks 1, 4, 8, and 12
Duration of Use of App - Adult Support Participants
Website usage metrics were captured by measuring the duration of website use by by support adults.
Measured: Weeks 1, 4, 8, and 12

Secondary outcomes (12)

Feasibility of Intervention Measure (FIM) - Youth Participants
Items were scored on a 5-point scale ranging from 1 to 5 (completely disagree to completely agree). Higher scores indicated higher perceived intervention feasibility. Results reflect data from Youth Participants.
Measured: At 4 Weeks
Feasibility of Intervention Measure (FIM) - Adult Caregiver Participants
Items were scored on a 5-point scale ranging from 1 to 5 (completely disagree to completely agree). Higher scores indicated higher perceived intervention feasibility. Results reflect data from Adult Caregiver Participants.
Measured: At 4 Weeks
Feasibility of Intervention Measure (FIM) - Adult Support Participants
Items were scored on a 5-point scale ranging from 1 to 5 (completely disagree to completely agree). Higher scores indicated higher perceived intervention feasibility. Results reflect data from Adult Support Participants.
Measured: At 8 Weeks
Acceptability of Intervention Measure (AIM) - Youth Participants
Items were scored on a 5-point scale ranging from 1 to 5 (completely disagree to completely agree). Higher scores indicated higher acceptability. Results reflect data from Youth Participants.
Measured: At 4 Weeks
Acceptability of Intervention Measure (AIM) - Adult Caregiver Participants
Items were scored on a 5-point scale ranging from 1 to 5 (completely disagree to completely agree). Higher scores indicated higher acceptability. Results reflect data from Adult Caregiver Participants.
Measured: At 4 Weeks
Acceptability of Intervention Measure (AIM) - Adult Support Participants
Items were scored on a 5-point scale ranging from 1 to 5 (completely disagree to completely agree). Higher scores indicated higher acceptability. Results reflect data from Adult Support Participants.
Measured: At 8 Weeks
Intervention Appropriateness Measure (IAM) - Youth Participants
Items were scored on a 5-point scale ranging from 1 to 5 (completely disagree to completely agree). Higher scores indicated higher perceived intervention appropriateness. Results reflect data from Youth Participants.
Measured: At 4 Weeks
Intervention Appropriateness Measure (IAM) - Adult Caregiver Participants
Items were scored on a 5-point scale ranging from 1 to 5 (completely disagree to completely agree). Higher scores indicated higher perceived intervention appropriateness. Results reflect data from Adult Caregiver Participants.
Measured: At 4 Weeks
Intervention Appropriateness Measure (IAM) - Adult Support Participants
Items were scored on a 5-point scale ranging from 1 to 5 (completely disagree to completely agree). Higher scores indicated higher perceived intervention appropriateness. Results reflect data from Adult Support Participants.
Measured: At 8 Weeks
Client Satisfaction Questionnaire (CSQ-I) - Youth Participants
The CSQ-I was a valid and reliable scale for measuring overall satisfaction with health and human services, including digital or internet-based intervention. This was adapted for use with youth, parents, and support adults. The adapted scales each had 8 items in a Likert scale ranging from 8-32 where higher numbers indicated higher satisfaction. Results reflect data from Youth Participants.
Measured: At 4 Weeks
Client Satisfaction Questionnaire (CSQ-I) - Adult Caregiver Participants
The CSQ-I was a valid and reliable scale for measuring overall satisfaction with health and human services, including digital or internet-based intervention. This was adapted for use with youth, parents, and support adults. The adapted scales each had 8 items in a Likert scale ranging from 8-32 where higher numbers indicated higher satisfaction. Results reflect data from Adult Caregiver Participants.
Measured: At 4 Weeks
Client Satisfaction Questionnaire (CSQ-I) - Adult Support Participants
The CSQ-I was a valid and reliable scale for measuring overall satisfaction with health and human services, including digital or internet-based intervention. This was adapted for use with youth, parents, and support adults. The adapted scales each had 8 items in a Likert scale ranging from 8-32 where higher numbers indicated higher satisfaction. Results reflect data from Adult Support Participants.
Measured: At 8 Weeks

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

27 Nov 202330 Sep 2024

First posted12 Jun 2023
Study start27 Nov 2023
Primary completion30 Sep 2024
Study completion30 Sep 2024

Resources

Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
Posted resultsParticipant flow, outcome measures and adverse events reported by the sponsor.
Other trials for SuicideStudies of the same condition, open and under way.
More trials run by University of MichiganThe sponsor's other registered studies.
What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design

Study type: Interventional
Phase: Phase N/A
Primary purpose: Prevention
Allocation: Not applicable
Intervention model: Single group
Masking: None (open label)
Enrolment: 75 participants (actual)

IDs, dates and publications

ClinicalTrials.gov ID: NCT05900700
Sponsor's protocol ID: HUM00221931
Other IDs: 5R43MH128431-02
Status last verified: Mar 2026
First submitted: 2 Jun 2023
Last updated: 18 Mar 2026
Results posted: Yes, on ClinicalTrials.gov
Data monitoring committee: No
FDA-regulated drug: No
FDA-regulated device: No
Individual data sharing: No

Want to know more?

The sponsor has not listed a contact. The official record may have more details.

Talk to your doctor first and take this page with you. Only the study team can confirm whether you can join.

Questions to ask the study team

What is the study trying to find out?
What would I need to do, and how often would I visit?
Could I receive a placebo instead of the treatment?
What are the possible risks and benefits for me?
Will it cost me anything? Are travel or time paid for?
Can I keep seeing my own doctor during the study?
What happens when the study ends?

See locations

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All Suicide trials

Study at a glance

From the registry record, last updated by the sponsor on 18 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.

Official title: An Open-Label Study of the Feasibility and Usability of a Digital Psychoeducational Social Network Intervention for Suicidal Adolescents
ClinicalTrials.gov ID: NCT05900700
Acronym / sponsor ID: HUM00221931
Conditions: Suicide
Keywords: Social network, Website
Study type: Interventional
Recruitment status: Completed
Enrolment: 75 participants (actual)
Lead sponsor: University of MichiganUniversity, hospital or other
Collaborators: National Institute of Mental Health (NIMH)
Study start: 27 Nov 2023 (actual)
Primary completion: 30 Sep 2024 (actual)
Study completion: 30 Sep 2024 (actual)
First posted: 12 Jun 2023 (actual)
Results: Posted 18 Mar 2026

Clinical summary

The research question as the sponsor registered it. This describes what the study plans to test, not what it found.

Detailed description

Assessment data from multiple stakeholders (i.e., youth, parents, and support adults) will be collected at baseline, 4 weeks, 8 weeks, and 12 weeks via self-report and semi-structured interviews.

Study design

Primary purpose: Prevention
Allocation: Not applicable
Intervention model: Single group
Masking: None (open label)
Number of arms: 1

Arm	Type	Receives
eYST website	Experimental	Behavioral: eYST website

Who may qualify

Ages: 13 to 17 years
Sex: All
Healthy volunteers: Not accepted
Age groups: Child

Key inclusion criteria (6 listed)

Inpatient psychiatric patients who have attempted suicide or have documented Suicide ideation (SI) and a plan to harm themselves at admission.
Understand written and spoken English.
Own a smartphone or mobile phone.
Willing and able to complete enrollment procedures.
Parent or guardian and youth able to understand the nature of the study and provide written informed consent and assent for youth

Key exclusion criteria (6 listed)

Patients with active psychosis.
Patients experiencing substance withdrawal.
Currently enrolled in other treatment studies for the symptoms and behaviors targeted.
Patient unwilling or unable to wear a mask during in person study procedures, if mandated due to current COVID/health safety guidelines.
Patients who in the judgment of the investigator would have an unfavorable risk or benefit profile with respect to eYST.

Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.

Interventions

Intervention	Type	Arms
eYST websiteThe website is a psychoeducational, social support program for adolescents at risk for suicide	Behavioural	eYST website

Primary outcome

System Usability Scale (SUS) Score - Youth Participants
Time frame: At 4 Weeks
10-item measure. Scores ranged from 0 to 100. The researchers calculated the mean score. A mean score of 68 was the minimal indicator of usability. Results reflect data from Youth Participants.
System Usability Scale (SUS) Score - Adult Caregiver Participants
Time frame: At 4 Weeks
10-item measure. Scores ranged from 0 to 100. The researchers calculated the mean score. A mean score of 68 was the minimal indicator of usability. Results reflect data from Adult Caregiver Participants.
System Usability Scale (SUS) Score - Adult Support Participants
Time frame: At 8 Weeks
10-item measure. Scores ranged from 0 to 100. The researchers calculated the mean score. A mean score of 68 was the minimal indicator of usability. Results reflect data from Adult Support Participants.
Frequency of Use of App - Youth Participants
Time frame: Weeks 1, 4, 8, and 12
Website usage metrics were captured by counting the number of website log-ins by Youth (adolescent) Participants.
Frequency of Use of App - Adult Caregiver Participants
Time frame: Weeks 1, 4, 8, and 12
Website usage metrics were captured by counting the number of website log-ins by parents/caregivers.
Frequency of Use of App - Adult Support Participants
Time frame: Week 1, 4, 8, 12
Website usage metrics were captured by counting the number of website log-ins by supporting adults.
Duration of Use of App - Youth Participants
Time frame: Weeks 1, 4, 8, and 12
Website usage metrics were captured by measuring the duration of website use by adolescents.
Duration of Use of App - Adult Caregiver Participants
Time frame: Weeks 1, 4, 8, and 12
Website usage metrics were captured by measuring the duration of website use by parents/caregivers.
Duration of Use of App - Adult Support Participants
Time frame: Weeks 1, 4, 8, and 12
Website usage metrics were captured by measuring the duration of website use by by support adults.

12 secondary outcomes

Feasibility of Intervention Measure (FIM) - Youth Participants
Time frame: At 4 Weeks
Feasibility of Intervention Measure (FIM) - Adult Caregiver Participants
Time frame: At 4 Weeks
Feasibility of Intervention Measure (FIM) - Adult Support Participants
Time frame: At 8 Weeks
Acceptability of Intervention Measure (AIM) - Youth Participants
Time frame: At 4 Weeks
Acceptability of Intervention Measure (AIM) - Adult Caregiver Participants
Time frame: At 4 Weeks
Acceptability of Intervention Measure (AIM) - Adult Support Participants
Time frame: At 8 Weeks
Intervention Appropriateness Measure (IAM) - Youth Participants
Time frame: At 4 Weeks
Intervention Appropriateness Measure (IAM) - Adult Caregiver Participants
Time frame: At 4 Weeks
Intervention Appropriateness Measure (IAM) - Adult Support Participants
Time frame: At 8 Weeks
Client Satisfaction Questionnaire (CSQ-I) - Youth Participants
Time frame: At 4 Weeks
Client Satisfaction Questionnaire (CSQ-I) - Adult Caregiver Participants
Time frame: At 4 Weeks
Client Satisfaction Questionnaire (CSQ-I) - Adult Support Participants
Time frame: At 8 Weeks

Results and safety

Results posted to the registry on 18 Mar 2026, as reported by the sponsor. Figures are copied from the record, not re-analysed. Full results on ClinicalTrials.gov.

Participant flow

Group	Started	Completed
eYST Website - Youth Participants	19	19
eYST Website - Adult Caregiver Participants	19	19
eYST Website - Adult Support Participant	0	0
eYST Website - Adult Caregiver and Adult Support Participants	0	0

Primary outcome: System Usability Scale (SUS) Score - Youth Participants

Time frame: At 4 Weeks. Mean (Standard Deviation). Unit: score on a scale

Measure	eYST Website - Youth Participants n = 18
Value	68.3 (17.6)

Population analysed: 1 youth participant was lost to follow up.

Primary outcome: System Usability Scale (SUS) Score - Adult Caregiver Participants

Time frame: At 4 Weeks. Mean (Standard Deviation). Unit: score on a scale

Measure	eYST Website - Adult Caregiver Participants n = 18
Value	75.6 (17.8)

Population analysed: This outcome includes data from all Caregivers regardless of whether they were also named by a Youth Participant as an Adult Support Participant. 1 caregiver participant withdrew from the trial prior to data collection.

Primary outcome: System Usability Scale (SUS) Score - Adult Support Participants

Time frame: At 8 Weeks. Mean (Standard Deviation). Unit: score on a scale

Measure	eYST Website - Adult Support Participant n = 39
Value	79.5 (16.4)

Population analysed: This outcome includes data from all Adult Support Participants regardless of whether they were also a Youth's Adult Caregiver. Data was not collected from 6 Adult Support Participants, as they did not complete the follow-up.

Primary outcome: Frequency of Use of App - Youth Participants

Time frame: Weeks 1, 4, 8, and 12. Mean (Full Range). Unit: Logins per week

Measure	eYST Website - Youth Participants n = 9
Week 1	1.0 (0 to 2)
Week 4	0.1 (0 to 1)
Week 8	0 (0 to 0)
Week 12	0 (0 to 0)

Population analysed: Usage information was gathered for 9 adolescent participants due to technological features that prevented analytics from tracking certain website data.

12 secondary outcomes are reported in the full results.

Adverse events

Time frame: 12 weeks. Other adverse events reported at 0% frequency or more

Group	Serious adverse events	Other adverse events	Deaths
eYST Website - Youth Participants	2 of 19 (10.5%)	0 of 19 (0%)	0 of 19

Loading the posted results from ClinicalTrials.gov…

Research links

Official record on ClinicalTrials.govLast updated by the sponsor 18 Mar 2026.
Posted resultsParticipant flow, baseline, all outcome measures and adverse events.
Individual participant dataSharing planned: No

Related trials for Suicide

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BEAR for Women Who Have Experienced Sexual Assault and Have Suicidal Thoughts
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Referral and contact

AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.

Alejandra Arango principal investigator

University of Michigan

Patricia Simon study director

Oui Therapeutics, Inc.

1 site in 1 country: see every site and its status.

Questions about this trial

What is this clinical trial studying?

A study testing eYST website in people with Suicide, run by University of Michigan at 1 site in United States.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 6 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 18 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

Yes. Results are posted in the registry (first posted 18 Mar 2026). A summary is in the For doctors view, and the full results are on ClinicalTrials.gov.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

System Usability Scale (SUS) Score - Youth Participants (time frame: At 4 Weeks). The study lists 9 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT05900700.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 18 Mar 2026.