Time Restricted EatingNCT05908201
Effects of Early Time Restricted Eating on Muscle Performance in Resistance Trained Individuals
A study testing early time restricted eating in people with Time Restricted Eating, run by University of Mississippi, Oxford at 1 site in United States.
Trial summary
A randomized controlled trial to determine the effectiveness of early time-restricted eating on muscle performance and body composition in active, resistance trained adults. Two parallel groups will be randomly assigned to either the early time-restricted eating or a control group. Read more about this study
- Who is it for?
- Ages 18 to 50 yearsHealthy volunteers can take part
- Conditions the study is for
- Time Restricted Eating
- What is being tested?
- early time restricted eating
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- 1 siteUnited States
- Study dates
- 20 Feb 2023to 17 Jun 2023
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 50 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Adults between 18 - 50 years
- Performing resistance training at least twice per week (for ≥1 yr)
- BMI ≥ 18.5
Who cannot join
- Currently sedentary or not engaged in resistance training.
- Major surgeries in muscles/joints during the past 3 months
- BMI < 18.5
- Ineligible to engage in physical activity according to 2022 Physical Activity Readiness Questionnaire for everyone (PAR-Q+)
- Take anabolic steroids or on hormone replacement therapy.
- Current smoker.
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- Following restrictive diets (Vegan, vegetarian, intermittent fasting, Paleo, calorie restriction, keto/ low carbohydrate diet or any other restrictive diets)
- Active cancer or cancer requiring treatment in the past 2 years (except non-melanoma skin cancer).
- Musculoskeletal disorders
- Diagnosed with cardiovascular disease including myocardial infarction, heart surgery, heart failure and had a heart transplant.
- Have pacemaker or metal implants
- Diagnosed diabetes (type 1 or 2).
- Diagnosed hypertension or high blood pressure (>130/90).
- Diagnosed eating disorder or score ≥ 20 on Eating Attitudes Test -26 (EAT26) survey
- Missing limbs/ have prosthetics
- Had surgery in joints/muscle in the past year.
- Received medical advise against exercising due to medical reasons.
- On medication for conditions related to the thyroid gland
- Unwilling to commit for a 7-week study
- Likely to move away from participating clinic before trial completed
- Unable or unwilling to give informed consent
- Another household member is a participant or staff member in the trial
- Unwilling to accept treatment assignment by randomization
- Current or anticipated participation in another intervention research project that would interfere with the intervention offered in the trial
- Pregnant or < 6 months since giving birth.
- Any other condition which, in opinion of investigators, that would adversely affect conduct of the trial.
Trial locations and contacts
1 site in 1 country.
United States1 site
Department of Nutrition and Hospitality Management, University of Mississippi
University, Mississippi, 38677
About this study
Official title: Effects of 6-weeks of Early Time Restricted Eating on Muscle Performance in Resistance Trained Individuals
A randomized controlled trial to determine the effectiveness of early time-restricted eating on muscle performance and body composition in active, resistance trained adults. Two parallel groups will be randomly assigned to either the early time-restricted eating or a control group. All participants will be asked to maintain their usual exercise routines during the 6 week intervention period. Muscle strength and endurance are the primary outcomes. Body composition (body weight, fat mass, fat-free mass and percent body fat), hunger and satiety ratings, sleep quality, energy intake, diet quality, macronutrient composition and adherence are secondary outcome measures.
- Conditions
- Time Restricted Eating
- Being tested
- early time restricted eating
- Keywords
- Intermittent fasting, Time restricted eating
- Medical subject headings
- Intermittent Fasting
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
early time restricted eatingBehavioural
The intervention group will eat in a prescribed daily feeding window (9am-5pm) and follow their normal exercise and resistance training routines. We will allow up till +/-1 hour for the eating window start and end times while aiming for an 8 hour eating window.
| Study group | Role | What they receive |
|---|---|---|
| early time-restricted eating | Experimental | The Early Time Restricted Eating (eTRE) group will be asked to consume calorie containing food or drinks only between 9am to 5pm, daily. At other times they are to avoid consuming any calorie containing food or drinks. Receives: Behavioral: early time restricted eating |
| Control | No intervention | The Control group will follow their usual eating routine. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Muscular strength
Pre and post intervention testing of muscular strength using one-rep max
Measured: 6-weeks
Muscular endurance
Pre and post intervention testing of muscular endurance using barbell bench press and squat.
Measured: 6-weeks
Secondary outcomes (10)
Body weight (kg)
Pre and post intervention measures of body weight.
Measured: 6-weeks
Hunger and satiety
Pre and post intervention subjective measure of hunger and satiety with the use of a Hunger and Satiety Visual Analog Scale (minimum value zero, maximum value 10). Higher the score, the more hungry/ less satiated one is.
Measured: 6-weeks
Sleep quality
Pre and post intervention measure of subjective sleep quality by use of Pittsburgh Sleep Quality Scale. (each question can be scored from 0-3, then an aggregate score of the whole survey can range from 0-21; The higher the score the worst the sleep quality).
Measured: 6-weeks
Total calorie intake
Pre and post intervention measurements of calorie intake based on 24-hour food recall survey using the Automated Self-Administered 24-hour (ASA24) software.
Measured: 6-weeks
Diet Quality
Pre and post intervention measurements of diet quality based on 24-hour food recall survey using the ASA24 software and Healthy Eating Index.
Measured: 6-weeks
Diet macronutrient composition
Pre and post intervention measurements of macronutrients based on 24-hour food recall survey using the ASA24 software.
Measured: 6-weeks
Adherence
Percent of days during the 6-week trial when eTRE was adhered to as recommended. This will be recorded by the participants daily throughout the entire study.
Measured: 6-weeks
Fat mass
Pre and post intervention measurements of body fat mass (kg).
Measured: 6-weeks
Fat-free mass
pre and post intervention measurements of body fat-free mass (kg).
Measured: 6-weeks
Body fat percentage
Pre and post intervention measurements of body fat percentage.
Measured: 6-weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted18 Jun 2023
- Study start20 Feb 2023
- Primary completion17 Jun 2023
- Study completion17 Jun 2023
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Time Restricted EatingStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 40 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Mississippi, Oxford
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05908201
- Sponsor's protocol ID
- 23-030
- Status last verified
- Dec 2024
- First submitted
- 21 Mar 2023
- Last updated
- 23 Jun 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: We will share the de-identified participant data used in the published manuscript/s by depositing these data in the Open Science Framework (OSF) repository. The data shared will include the sociodemographic data and the outcomes published in the manuscripts. The protocol and statistical analysis plan will be shared as supplementary material through the journal where the study if published, if allowed.
Study at a glance
From the registry record, last updated by the sponsor on 23 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of 6-weeks of Early Time Restricted Eating on Muscle Performance in Resistance Trained Individuals
- ClinicalTrials.gov ID
- NCT05908201
- Acronym / sponsor ID
- 23-030
- Conditions
- Time Restricted Eating
- Keywords
- Intermittent fasting, Time restricted eating
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 40 participants (actual)
- Lead sponsor
- University of Mississippi, OxfordUniversity, hospital or other
- Study start
- 20 Feb 2023 (actual)
- Primary completion
- 17 Jun 2023 (actual)
- Study completion
- 17 Jun 2023 (actual)
- First posted
- 18 Jun 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
A randomized controlled trial to determine the effectiveness of early time-restricted eating on muscle performance and body composition in active, resistance trained adults. Two parallel groups will be randomly assigned to either the early time-restricted eating or a control group. All participants will be asked to maintain their usual exercise routines during the 6 week intervention period. Muscle strength and endurance are the primary outcomes. Body composition (body weight, fat mass, fat-free mass and percent body fat), hunger and satiety ratings, sleep quality, energy intake, diet quality, macronutrient composition and adherence are secondary outcome measures.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| early time-restricted eating | Experimental | Behavioral: early time restricted eatingThe Early Time Restricted Eating (eTRE) group will be asked to consume calorie containing food or drinks only between 9am to 5pm, daily. At other times they are to avoid consuming any calorie containing food or drinks. |
| Control | No intervention | –The Control group will follow their usual eating routine. |
Who may qualify
- Ages
- 18 to 50 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (3 listed)
- Adults between 18 - 50 years
- Performing resistance training at least twice per week (for ≥1 yr)
- BMI ≥ 18.5
Key exclusion criteria (26 listed)
- Currently sedentary or not engaged in resistance training.
- Major surgeries in muscles/joints during the past 3 months
- BMI < 18.5
- Ineligible to engage in physical activity according to 2022 Physical Activity Readiness Questionnaire for everyone (PAR-Q+)
- Take anabolic steroids or on hormone replacement therapy.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| early time restricted eatingThe intervention group will eat in a prescribed daily feeding window (9am-5pm) and follow their normal exercise and resistance training routines. We will allow up till +/-1 hour for the eating window start and end times while aiming for an 8 hour eating window. | Behavioural | early time-restricted eating |
Primary outcome
Muscular strength
Time frame: 6-weeks
Pre and post intervention testing of muscular strength using one-rep max
Muscular endurance
Time frame: 6-weeks
Pre and post intervention testing of muscular endurance using barbell bench press and squat.
10 secondary outcomes
Body weight (kg)
Time frame: 6-weeks
Hunger and satiety
Time frame: 6-weeks
Sleep quality
Time frame: 6-weeks
Total calorie intake
Time frame: 6-weeks
Diet Quality
Time frame: 6-weeks
Diet macronutrient composition
Time frame: 6-weeks
Adherence
Time frame: 6-weeks
Fat mass
Time frame: 6-weeks
Fat-free mass
Time frame: 6-weeks
Body fat percentage
Time frame: 6-weeks
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 23 Jun 2026.
- Individual participant dataSharing planned: Yes. We will share the de-identified participant data used in the published manuscript/s by depositing these data in the Open Science Framework (OSF) repository. The data shared will include the sociodemographic data and the outcomes published in the manuscripts. The protocol and statistical analysis plan will be shared as supplementary material through the journal where the study if published, if allowed.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing early time restricted eating in people with Time Restricted Eating, run by University of Mississippi, Oxford at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 26 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 23 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Muscular strength (time frame: 6-weeks). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 Jun 2026.