Parkinson's DiseaseNCT05929781
Turning Pattern of Different Body Segments During Turns and Turning Performance
An observational study of Parkinson's Disease, run by National Yang Ming Chiao Tung University at 1 site in Taiwan.
Trial summary
This is a cross-sectional exploratory study. A total of 25 people with PD, 25 young healthy adults, and 25 middle to older adults will be recruited. Axial segment turning pattern and turning performance will be evaluated in two visits using the Vicon 3D motion analysis system, Gaitup, and 3D motion camera. Read more about this study
- Who is it for?
- Ages 20 to 80 yearsHealthy volunteers can take part
- Conditions the study is for
- Parkinson's Disease
- How many people
- 30 participants
- Where
- 1 siteTaiwan
- Study dates
- 5 Dec 2023to 31 Aug 2024
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 80 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: 1. Young healthy adults 2. Middle to older adults 3. People with Parkinson's disease
Who may be able to join
- Able to walk 5 meters without assistance device
- Able to turn independently
Who cannot join
- With neurological disorders
- MMSE< 24
- Any systemic and musculoskeletal disturbances or other causes of walking inability
Trial locations and contacts
1 site in 1 country.
Taiwan1 site
Department of Physical Therapy and Assistive Technology, National Yang Ming Chiao Tung University
Taipei, 112
About this study
Official title: Turning Pattern of Different Body Segments During Turns and Turning Performance in Healthy Adults and People With Parkinson's Disease
This is a cross-sectional exploratory study. A total of 25 people with PD, 25 young healthy adults, and 25 middle to older adults will be recruited. Axial segment turning pattern and turning performance will be evaluated in two visits using the Vicon 3D motion analysis system, Gaitup, and 3D motion camera. The independent variables are the initiation timing of the head, upper trunk, pelvis, ankle, and foot when turning and the initiation sequence of turning (% turn). The dependent variables are turning performance, including turning velocity, turning steps, turning step length, turning step width), and stance phase (%).
Read the detailed description
The first aim of the present study is to explore the correlation between axial segment turning pattern and turning performance in people with PD and healthy adults.
The second aim is to verify the validity and reliability of 3D motion camera in turning evaluation.
A total of 25 people with PD, 25 young healthy adults, and 25 middle to older adults will be recruited.
Axial segment turning pattern and turning performance will be evaluated in two visits using the Vicon 3D motion analysis system, Gaitup, and 3D motion camera.
The independent variables are the initiation timing of the head, upper trunk, pelvis, ankle, and foot when turning and the initiation sequence of turning (% turn). The dependent variables are turning performance, including turning velocity, turning steps, turning step length, turning step width), and stance phase (%).
For the data analysis, the Shapiro-Wilk test will be used to check for normal distribution. Pearson's correlation coefficient or Spearman's rank correlation coefficient will be used to examine the correlations between axial segment initiation timing and turning performance. To verify the validity and reliability, Pearson's correlation coefficient will be used for concurrent criterion validity. Intraclass correlation one-way random model will be used for test-retest reliability, showed with intraclass correlation coefficient and 95% confidence interval. A p-value of less than 0.05 is considered statistically significant.
- Conditions
- Parkinson's Disease
- Keywords
- Parkinson's disease, Turning, Inter-segmental coordination, En bloc turning, Turning performance
- Medical subject headings
- Parkinson Disease
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Young healthy adults | 1. 20-39 years old | |
| Middle to older healthy adults | 1. 40-80 years old 2. age-matched with People with Parkinson's disease group | |
| People with Parkinson's disease | 1. 40-80 years old 2. Diagnosis of idiopathic Parkinson's disease 3. Hoehn and Yahr stage 1-2 |
What is being measured
The primary outcome is the main question the study is designed to answer.
Initiation timing (sec)
Initiation timing of the head, upper trunk, pelvis, ankle, and foot when turning
Measured: Change from baseline at one week
Turning velocity (cm/sec)
Measured: Change from baseline at one week
Turning steps
Measured: Change from baseline at one week
Turning step length (cm)
Measured: Change from baseline at one week
Turning step width (cm)
Measured: Change from baseline at one week
Stance phase (%)
Measured: Change from baseline at one week
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted3 Jul 2023
- Study start5 Dec 2023
- Primary completion21 Jul 2024
- Study completion31 Aug 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Parkinson's DiseaseStudies of the same condition, open and under way.
- More trials run by National Yang Ming Chiao Tung UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Cross-sectional
- Enrolment
- 30 participants (actual)
Sponsor and investigators
- Lead sponsor
- National Yang Ming Chiao Tung University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Yea-Ru Yang, National Yang Ming Chiao Tung University
- Investigators
- Yea-Ru Yang, Ph.D., Study chair, Department of Physical Therapy and Assistive Technology, National Yang Ming Chiao Tung University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05929781
- Sponsor's protocol ID
- NYCU112100AE
- Status last verified
- Jun 2025
- First submitted
- 21 Jun 2023
- Last updated
- 13 Jun 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: This is a preliminary study and also with small sample size, so currently no plan to share data with other researchers
Study at a glance
From the registry record, last updated by the sponsor on 13 Jun 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Turning Pattern of Different Body Segments During Turns and Turning Performance in Healthy Adults and People With Parkinson's Disease
- ClinicalTrials.gov ID
- NCT05929781
- Acronym / sponsor ID
- NYCU112100AE
- Conditions
- Parkinson's Disease
- Keywords
- Parkinson's disease, Turning, Inter-segmental coordination, En bloc turning, Turning performance
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 30 participants (actual)
- Lead sponsor
- National Yang Ming Chiao Tung UniversityUniversity, hospital or other
- Study start
- 5 Dec 2023 (actual)
- Primary completion
- 21 Jul 2024 (actual)
- Study completion
- 31 Aug 2024 (actual)
- First posted
- 3 Jul 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This is a cross-sectional exploratory study. A total of 25 people with PD, 25 young healthy adults, and 25 middle to older adults will be recruited. Axial segment turning pattern and turning performance will be evaluated in two visits using the Vicon 3D motion analysis system, Gaitup, and 3D motion camera. The independent variables are the initiation timing of the head, upper trunk, pelvis, ankle, and foot when turning and the initiation sequence of turning (% turn). The dependent variables are turning performance, including turning velocity, turning steps, turning step length, turning step width), and stance phase (%).
Detailed description
The first aim of the present study is to explore the correlation between axial segment turning pattern and turning performance in people with PD and healthy adults.
The second aim is to verify the validity and reliability of 3D motion camera in turning evaluation.
A total of 25 people with PD, 25 young healthy adults, and 25 middle to older adults will be recruited.
Axial segment turning pattern and turning performance will be evaluated in two visits using the Vicon 3D motion analysis system, Gaitup, and 3D motion camera.
The independent variables are the initiation timing of the head, upper trunk, pelvis, ankle, and foot when turning and the initiation sequence of turning (% turn). The dependent variables are turning performance, including turning velocity, turning steps, turning step length, turning step width), and stance phase (%).
For the data analysis, the Shapiro-Wilk test will be used to check for normal distribution. Pearson's correlation coefficient or Spearman's rank correlation coefficient will be used to examine the correlations between axial segment initiation timing and turning performance. To verify the validity and reliability, Pearson's correlation coefficient will be used for concurrent criterion validity. Intraclass correlation one-way random model will be used for test-retest reliability, showed with intraclass correlation coefficient and 95% confidence interval. A p-value of less than 0.05 is considered statistically significant.
Study design
- Observational model
- Other
- Time perspective
- Cross-sectional
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Young healthy adults | – | –1. 20-39 years old |
| Middle to older healthy adults | – | –1. 40-80 years old 2. age-matched with People with Parkinson's disease group |
| People with Parkinson's disease | – | –1. 40-80 years old 2. Diagnosis of idiopathic Parkinson's disease 3. Hoehn and Yahr stage 1-2 |
Who may qualify
- Ages
- 20 to 80 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- 1. Young healthy adults 2. Middle to older adults 3. People with Parkinson's disease
Key inclusion criteria (2 listed)
- Able to walk 5 meters without assistance device
- Able to turn independently
Key exclusion criteria (3 listed)
- With neurological disorders
- MMSE< 24
- Any systemic and musculoskeletal disturbances or other causes of walking inability
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Initiation timing (sec)
Time frame: Change from baseline at one week
Initiation timing of the head, upper trunk, pelvis, ankle, and foot when turning
Turning velocity (cm/sec)
Time frame: Change from baseline at one week
Turning steps
Time frame: Change from baseline at one week
Turning step length (cm)
Time frame: Change from baseline at one week
Turning step width (cm)
Time frame: Change from baseline at one week
Stance phase (%)
Time frame: Change from baseline at one week
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 13 Jun 2025.
- Individual participant dataSharing planned: No. This is a preliminary study and also with small sample size, so currently no plan to share data with other researchers
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Yea-Ru Yang, Ph.D. study chair
Department of Physical Therapy and Assistive Technology, National Yang Ming Chiao Tung University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Parkinson's Disease, run by National Yang Ming Chiao Tung University at 1 site in Taiwan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 13 Jun 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Taiwan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Initiation timing (sec) (time frame: Change from baseline at one week). The study lists 6 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 13 Jun 2025.