CancerNCT05941858
Online Tai Chi Intervention to Promote Smoking Cessation Among Cancer Survivors
A study testing Smoking Cessation Intervention, Carbon Monoxide Measurement and Internet-Based Intervention in people with Cancer, run by Ohio State University Comprehensive Cancer Center at 1 site in United States.
Trial summary
This clinical trial evaluates an online Tai Chi intervention to promote smoking cessation among cancer survivors. Tai chi is a practice that involves a series of slow gentle movements and physical postures, a meditative state of mind, and controlled breathing. Read more about this study
- Who is it for?
- Ages 21 years and older
- Conditions the study is for
- Cancer
- What is being tested?
- Smoking Cessation Intervention, Carbon Monoxide Measurement and Internet-Based Intervention
- Type of treatment
- Surgery or procedure, Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 68 participants
- Where
- 1 siteUnited States
- Study dates
- 11 Nov 2024to 10 Dec 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 21 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Cancer survivor (i.e., have had a cancer diagnosis)
- Age 21 years and older
- English speaking/reading
- Report smoking tobacco in the past 30 days
- Report at least moderate interest in quitting smoking (>= 3 on a Likert type scale with 5 being very extremely interested)
- Can participate in Zoom calls for orientation and intervention
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- Have access to a smartphone or tablet
- Willing to download a free application (app)
- Can commit to the 8-weeks intervention (WaQi program)
- Are not currently or have not regularly practiced Tai Chi in the last 6 months
- Willing to blow into a device (for carbon monoxide measurements)
Who cannot join
- Non-cancer survivors
- Patients under 21 years old
- Non-English speaking/reading
- Non-smokers in the past 30 days
- Report lower than moderate interest in quitting smoking (< 3 on a Likert type scale with 5 being very extremely interested)
- Cannot to participate Zoom calls for orientation and intervention
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- No access to a smartphone or tablet
- Not willing to download a free app
- Cannot commit to the intervention
- Has practiced Tai Chi regularly in the last 6 months
- Not willing to blow into a device
- Eligible, but sampling quotas full
Trial locations and contacts
1 site in 1 country.
United States1 site
Ohio State University Comprehensive Cancer Center
Columbus, Ohio, 43210
About this study
Official title: A Tai Chi Intervention to Promote Smoking Cessation Among Cancer Survivors
This clinical trial evaluates an online Tai Chi intervention to promote smoking cessation among cancer survivors. Tai chi is a practice that involves a series of slow gentle movements and physical postures, a meditative state of mind, and controlled breathing. It is a gentle form of exercise that can be done while sitting or standing and does not involve any medications or medical procedures. Tai chi originated as an ancient martial art in China. Over the years, it has become more focused on health promotion and rehabilitation. The use of Tai Chi may be beneficial for cancer patients who want to quit smoking.
Read the detailed description
Aim 1: The primary objective of this study is to pilot an online Tai Chi intervention promoting smoking cessation among cancer survivors1.
Aim 2: Examine whether an online Tai Chi intervention reduces cigarette dependence among cancer survivors who are aged 21 and are interested in quitting smoking.
Aim 3: Test whether an online Tai Chi intervention increases quit attempts and cessation abstinence among cancer survivors who are aged 21 or older and are interested in quitting smoking.
OUTLINE: Participants are randomized to 1 of 2 arms.
ARM I: Participants participate in an 8-week supervised online WaQi/Tai Chi program. Participants receive standard cessation treatment which includes receiving a document highlighting smoking cessation resources.
ARM II: Participants receive standard cessation treatment which includes receiving a document highlighting smoking cessation resources. Participants also receive an 8-week online Tai Chi self-administered teaching module subscription at the end of the study.
- Conditions
- Cancer
- Being tested
- Smoking Cessation Intervention, Carbon Monoxide Measurement, Internet-Based Intervention, Survey Administration, Tai Chi
- Keywords
- Smoking Cessation, Tai Chi
- Medical subject headings
- Neoplasms, Smoking Cessation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Smoking Cessation InterventionBehavioural
Also called Smoking and Tobacco Use Cessation Interventions
Receive smoking cessation resource document
Carbon Monoxide MeasurementProcedure or surgery
Also called Carbon Monoxide, iCOquit
Undergo CO test
Internet-Based InterventionOther
Receive access to WaQi/Tai Chi program
Survey AdministrationOther
Ancillary studies
Tai ChiOther
Practice Tai Chi
| Study group | Role | What they receive |
|---|---|---|
| Arm I (Tai Chi) | Experimental | Participants receive access to the online WaQi program to practice Tai Chi supervised over 60 minutes BIW and home-based over 10 minutes five days a week for 8 weeks. Participants also receive a document highlighting NCI resources for quitting smoking including NCI's tollfree Quitline number, state Quitline numbers and other resources, and undergo CO testing on study. Receives: Behavioral: Smoking Cessation Intervention; Procedure: Carbon Monoxide Measurement; Other: Internet-Based Intervention; Other: Survey Administration; Other: Tai Chi |
| Arm II (Standard cessation) | Active comparator | Participants receive a document highlighting NCI resources for quitting smoking including NCI's tollfree Quitline number, state Quitline numbers and other resources, and undergo CO testing on study. Participants also receive an 8-week online Tai Chi self-administered teaching module subscription at the end of the study. Receives: Behavioral: Smoking Cessation Intervention; Procedure: Carbon Monoxide Measurement; Other: Internet-Based Intervention; Other: Survey Administration; Other: Tai Chi |
What is being measured
The primary outcome is the main question the study is designed to answer.
Smoking cessation
Will be assessed by the participants in both groups by carbon monoxide (CO) verification and self-administered online surveys.
Measured: At baseline, 4 weeks after start of intervention, and 1 week, 3 months and 6 months post-intervention
Quit attempts
Will be assessed by the participants in both groups by CO verification and self-administered online surveys.
Measured: Will be assessed by the participants in both groups by CO verification and self-administered online surveys.
Smoking abstinence
Will be assessed by the amount of CO in a participant's breath using a portable carbon monoxide monitor, which is synced to the participants' smartphones and will ask participants to complete a brief smoking habit survey.
Measured: At baseline, 4 weeks after start of intervention, and 1 week, 3 months and 6 months post-intervention
Secondary outcomes (2)
Cigarette Dependence Scale (12 item)
This outcome will be assessed by the participants completing self-administered online survey that includes 12 questions.
Measured: Up to 6 months post-intervention
Secondary measures that may contribute to smoking
Will include measures such as, anxiety and depression, physical activity, and pain. Will be assessed by the participants in both groups by self-administered online surveys.
Measured: At baseline, 1 week, 3 months and 6 months post-intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted12 Jul 2023
- Study start11 Nov 2024
- Primary completion10 Dec 2025
- Study completion10 Dec 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for CancerStudies of the same condition, open and under way.
- More trials run by Ohio State University Comprehensive Cancer CenterThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 68 participants (actual)
Sponsor and investigators
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ce Shang, Ohio State University Comprehensive Cancer Center
- Investigators
- Ce Shang, PhD, Principal investigator, Ohio State University Comprehensive Cancer Center
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05941858
- Sponsor's protocol ID
- OSU-22271
- Other IDs
- NCI-2023-04163
- Status last verified
- Mar 2026
- First submitted
- 2 Jun 2023
- Last updated
- 2 Apr 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 2 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Tai Chi Intervention to Promote Smoking Cessation Among Cancer Survivors
- ClinicalTrials.gov ID
- NCT05941858
- Acronym / sponsor ID
- OSU-22271
- Conditions
- Cancer
- Keywords
- Smoking Cessation, Tai Chi
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 68 participants (actual)
- Lead sponsor
- Ohio State University Comprehensive Cancer CenterUniversity, hospital or other
- Study start
- 11 Nov 2024 (actual)
- Primary completion
- 10 Dec 2025 (actual)
- Study completion
- 10 Dec 2025 (actual)
- First posted
- 12 Jul 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This clinical trial evaluates an online Tai Chi intervention to promote smoking cessation among cancer survivors. Tai chi is a practice that involves a series of slow gentle movements and physical postures, a meditative state of mind, and controlled breathing. It is a gentle form of exercise that can be done while sitting or standing and does not involve any medications or medical procedures. Tai chi originated as an ancient martial art in China. Over the years, it has become more focused on health promotion and rehabilitation. The use of Tai Chi may be beneficial for cancer patients who want to quit smoking.
Detailed description
Aim 1: The primary objective of this study is to pilot an online Tai Chi intervention promoting smoking cessation among cancer survivors1.
Aim 2: Examine whether an online Tai Chi intervention reduces cigarette dependence among cancer survivors who are aged 21 and are interested in quitting smoking.
Aim 3: Test whether an online Tai Chi intervention increases quit attempts and cessation abstinence among cancer survivors who are aged 21 or older and are interested in quitting smoking.
OUTLINE: Participants are randomized to 1 of 2 arms.
ARM I: Participants participate in an 8-week supervised online WaQi/Tai Chi program. Participants receive standard cessation treatment which includes receiving a document highlighting smoking cessation resources.
ARM II: Participants receive standard cessation treatment which includes receiving a document highlighting smoking cessation resources. Participants also receive an 8-week online Tai Chi self-administered teaching module subscription at the end of the study.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Arm I (Tai Chi) | Experimental | Behavioral: Smoking Cessation Intervention, Procedure: Carbon Monoxide Measurement, Other: Internet-Based Intervention, Other: Survey Administration, Other: Tai ChiParticipants receive access to the online WaQi program to practice Tai Chi supervised over 60 minutes BIW and home-based over 10 minutes five days a week for 8 weeks. Participants also receive a document highlighting NCI resources for quitting smoking including NCI's tollfree Quitline number, state Quitline numbers and other resources, and undergo CO testing on study. |
| Arm II (Standard cessation) | Active comparator | Behavioral: Smoking Cessation Intervention, Procedure: Carbon Monoxide Measurement, Other: Internet-Based Intervention, Other: Survey Administration, Other: Tai ChiParticipants receive a document highlighting NCI resources for quitting smoking including NCI's tollfree Quitline number, state Quitline numbers and other resources, and undergo CO testing on study. Participants also receive an 8-week online Tai Chi self-administered teaching module subscription at the end of the study. |
Who may qualify
- Ages
- 21 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (11 listed)
- Cancer survivor (i.e., have had a cancer diagnosis)
- Age 21 years and older
- English speaking/reading
- Report smoking tobacco in the past 30 days
- Report at least moderate interest in quitting smoking (>= 3 on a Likert type scale with 5 being very extremely interested)
Key exclusion criteria (12 listed)
- Non-cancer survivors
- Patients under 21 years old
- Non-English speaking/reading
- Non-smokers in the past 30 days
- Report lower than moderate interest in quitting smoking (< 3 on a Likert type scale with 5 being very extremely interested)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Smoking Cessation InterventionAlso: Smoking and Tobacco Use Cessation InterventionsReceive smoking cessation resource document | Behavioural | Arm I (Tai Chi), Arm II (Standard cessation) |
| Carbon Monoxide MeasurementAlso: Carbon Monoxide, iCOquitUndergo CO test | Procedure or surgery | Arm I (Tai Chi), Arm II (Standard cessation) |
| Internet-Based InterventionReceive access to WaQi/Tai Chi program | Other | Arm I (Tai Chi), Arm II (Standard cessation) |
| Survey AdministrationAncillary studies | Other | Arm I (Tai Chi), Arm II (Standard cessation) |
| Tai ChiPractice Tai Chi | Other | Arm I (Tai Chi), Arm II (Standard cessation) |
Primary outcome
Smoking cessation
Time frame: At baseline, 4 weeks after start of intervention, and 1 week, 3 months and 6 months post-intervention
Will be assessed by the participants in both groups by carbon monoxide (CO) verification and self-administered online surveys.
Quit attempts
Time frame: Will be assessed by the participants in both groups by CO verification and self-administered online surveys.
Will be assessed by the participants in both groups by CO verification and self-administered online surveys.
Smoking abstinence
Time frame: At baseline, 4 weeks after start of intervention, and 1 week, 3 months and 6 months post-intervention
Will be assessed by the amount of CO in a participant's breath using a portable carbon monoxide monitor, which is synced to the participants' smartphones and will ask participants to complete a brief smoking habit survey.
2 secondary outcomes
Cigarette Dependence Scale (12 item)
Time frame: Up to 6 months post-intervention
Secondary measures that may contribute to smoking
Time frame: At baseline, 1 week, 3 months and 6 months post-intervention
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Apr 2026.
- The JameslineLink provided by the sponsor.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Ce Shang, PhD principal investigator
Ohio State University Comprehensive Cancer Center
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Smoking Cessation Intervention, Carbon Monoxide Measurement and Internet-Based Intervention in people with Cancer, run by Ohio State University Comprehensive Cancer Center at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 11 inclusion and 12 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 2 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Smoking cessation (time frame: At baseline, 4 weeks after start of intervention, and 1 week, 3 months and 6 months post-intervention). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Apr 2026.