AthletesNCT05958056
Low Load Resistance Exercises With Blood Flow Restriction Versus High Load Resistance Exercises
A study testing Resistance exercise in people with Athletes, run by University of Jordan at 1 site in Jordan.
Trial summary
Practical blood flow restriction (PBFR) is a new technique of reducing the venous return using a band with a pressure that is applied using a perceived pressure scale. The studies that investigate the acute effect of using PBFR and regular high intensity exercises on the level of growth hormone (GH) and blood lactate… Read more about this study
- Who is it for?
- Ages 18 to 60 years, men onlyHealthy volunteers can take part
- Conditions the study is for
- Athletes
- What is being tested?
- Resistance exercise
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 22 participants
- Where
- 1 siteJordan
- Study dates
- 1 Mar 2021to 1 Jul 2022
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 60 years
- Men only
- Healthy volunteers accepted
- Adult
Who may be able to join
- Student collegiate athletes.
- Age of 18 years and older.
- Free from any cardiovascular or respiratory disorders and did not have any injuries during the previous 12 months.
Who cannot join
- Students who were taking any medications for chronic conditions.
- Student who were taking any supplements.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: The Acute Effect of Low Load Resistance Exercises With Blood Flow Restriction Versus High Load Resistance Exercises on Growth Hormone and Blood Lactate
Practical blood flow restriction (PBFR) is a new technique of reducing the venous return using a band with a pressure that is applied using a perceived pressure scale. The studies that investigate the acute effect of using PBFR and regular high intensity exercises on the level of growth hormone (GH) and blood lactate (BL) after lower extremity training in collegiate athletes are scarce.
Read the detailed description
Practical blood flow restriction (PBFR) is a new technique of reducing the venous return using a band with a pressure that is applied using a perceived pressure scale. The studies that investigate the acute effect of using PBFR and regular high intensity exercises on the level of growth hormone (GH) and blood lactate (BL) after lower extremity training in collegiate athletes are scarce. Therefore, this study aimed to investigate the acute effect of a single session low load resistance exercises with PBFR compared to a high load resistance exercises without PBFR on the levels of GH and BL. A convenience sample of collegiate athletes were allocated to either an experimental group that performed low resistance exercises with PBFR or a control group that performed high resistance exercises without PBFR. The levels of GH and BL were examined in 3 time points: pre-training, immediate post-training, and 15 minutes post-training for both groups. Analysis of Variance (ANOVA) was used to assess the main and interaction effects of the groups.
- Conditions
- Athletes
- Being tested
- Resistance exercise
- Keywords
- blood flow restriction, Growth hormone, Blood lactate
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Resistance exerciseOther
The training session included leg curl and leg extension exercises with 4 sets each. Participants started with leg extension exercise for 4 sets with a 30-second rest periods between the sets. Then, participants took a rest for 60 seconds. Afterward, participants performed leg curl exercise for 4 sets with a 30-second rest periods between the sets. Exercises in each set were performed continuously (uninterrupted) with a speed of 2 seconds for each repetition and a medium exercise performance speed.
| Study group | Role | What they receive |
|---|---|---|
| Low load resistance exercises with Practical blood flow restriction (PBFR) | Experimental | Participants in the experimental group performed one session of 30% 1RM with Practical blood flow restriction training. The number of repetitions in every set was 15 times with PBFR.19 Participants in the experimental group used the elite band (occlusion training bands) for both thighs during the training session. The width of the thigh band was 5cm, which would produce a pressure between 160-240 mmHg. This pressure range is appropriate for most of the individuals who used PBFR.27 The perceived pressure scale (PPS) was used to estimate the appropriate pressure (7 out of 10) in training before performing the exercises.28,29 The blood flow restriction bands booklet was used30 along with previous studies to design the training session. Participants removed the BFR band immediately after the end of the training session. Receives: Other: Resistance exercise |
| High resistance exercises | Active comparator | Participants in the control group performed one session of 80% 1RM without PBFR. The number of repetitions in every set was 10 times. Receives: Other: Resistance exercise |
What is being measured
The primary outcome is the main question the study is designed to answer.
Growth Hormone
Blood test of the level of growth hormone
Measured: Before intervention.
Growth Hormone
Blood test of the level of growth hormone
Measured: Immediately post intervention.
Growth Hormone
Blood test of the level of growth hormone
Measured: 15 minutes after the end of intervention.
Blood lactate
Blood test of the level of Blood lactate
Measured: Before intervention.
Blood lactate
Blood test of the level of Blood lactate
Measured: Immediately post intervention.
Blood lactate
Blood test of the level of Blood lactate
Measured: 15 minutes after the end of intervention.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted24 Jul 2023
- Study start1 Mar 2021
- Primary completion1 Dec 2021
- Study completion1 Jul 2022
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for AthletesStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Screening
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 22 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Jordan
- Sponsor type
- University, hospital or other
- Collaborators
- The Hashemite University
- Responsible party
- Principal investigator, Alia A. Alghwiri, University of Jordan
- Investigators
- Alia Alghwiri, PhD, Study director, University of Jordan
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05958056
- Sponsor's protocol ID
- 4/2019
- Status last verified
- Aug 2023
- First submitted
- 14 Jul 2023
- Last updated
- 16 Aug 2023
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 16 Aug 2023. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Acute Effect of Low Load Resistance Exercises With Blood Flow Restriction Versus High Load Resistance Exercises on Growth Hormone and Blood Lactate
- ClinicalTrials.gov ID
- NCT05958056
- Acronym / sponsor ID
- 4/2019
- Conditions
- Athletes
- Keywords
- blood flow restriction, Growth hormone, Blood lactate
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 22 participants (actual)
- Lead sponsor
- University of JordanUniversity, hospital or other
- Collaborators
- The Hashemite University
- Study start
- 1 Mar 2021 (actual)
- Primary completion
- 1 Dec 2021 (actual)
- Study completion
- 1 Jul 2022 (actual)
- First posted
- 24 Jul 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Practical blood flow restriction (PBFR) is a new technique of reducing the venous return using a band with a pressure that is applied using a perceived pressure scale. The studies that investigate the acute effect of using PBFR and regular high intensity exercises on the level of growth hormone (GH) and blood lactate (BL) after lower extremity training in collegiate athletes are scarce.
Detailed description
Practical blood flow restriction (PBFR) is a new technique of reducing the venous return using a band with a pressure that is applied using a perceived pressure scale. The studies that investigate the acute effect of using PBFR and regular high intensity exercises on the level of growth hormone (GH) and blood lactate (BL) after lower extremity training in collegiate athletes are scarce. Therefore, this study aimed to investigate the acute effect of a single session low load resistance exercises with PBFR compared to a high load resistance exercises without PBFR on the levels of GH and BL. A convenience sample of collegiate athletes were allocated to either an experimental group that performed low resistance exercises with PBFR or a control group that performed high resistance exercises without PBFR. The levels of GH and BL were examined in 3 time points: pre-training, immediate post-training, and 15 minutes post-training for both groups. Analysis of Variance (ANOVA) was used to assess the main and interaction effects of the groups.
Study design
- Primary purpose
- Screening
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Low load resistance exercises with Practical blood flow restriction (PBFR) | Experimental | Other: Resistance exerciseParticipants in the experimental group performed one session of 30% 1RM with Practical blood flow restriction training. The number of repetitions in every set was 15 times with PBFR.19 Participants in the experimental group used the elite band (occlusion training bands) for both thighs during the training session. The width of the thigh band was 5cm, which would produce a pressure between 160-240 mmHg. This pressure range is appropriate for most of the individuals who used PBFR.27 The perceived pressure scale (PPS) was used to estimate the appropriate pressure (7 out of 10) in training before performing the exercises.28,29 The blood flow restriction bands booklet was used30 along with previous studies to design the training session. Participants removed the BFR band immediately after the end of the training session. |
| High resistance exercises | Active comparator | Other: Resistance exerciseParticipants in the control group performed one session of 80% 1RM without PBFR. The number of repetitions in every set was 10 times. |
Who may qualify
- Ages
- 18 to 60 years
- Sex
- Male only
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (3 listed)
- Student collegiate athletes.
- Age of 18 years and older.
- Free from any cardiovascular or respiratory disorders and did not have any injuries during the previous 12 months.
Key exclusion criteria (2 listed)
- Students who were taking any medications for chronic conditions.
- Student who were taking any supplements.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Resistance exerciseThe training session included leg curl and leg extension exercises with 4 sets each. Participants started with leg extension exercise for 4 sets with a 30-second rest periods between the sets. Then, participants took a rest for 60 seconds. Afterward, participants performed leg curl exercise for 4 sets with a 30-second rest periods between the sets. Exercises in each set were performed continuously (uninterrupted) with a speed of 2 seconds for each repetition and a medium exercise performance speed. | Other | High resistance exercises, Low load resistance exercises with Practical blood flow restriction (PBFR) |
Primary outcome
Growth Hormone
Time frame: Before intervention.
Blood test of the level of growth hormone
Growth Hormone
Time frame: Immediately post intervention.
Blood test of the level of growth hormone
Growth Hormone
Time frame: 15 minutes after the end of intervention.
Blood test of the level of growth hormone
Blood lactate
Time frame: Before intervention.
Blood test of the level of Blood lactate
Blood lactate
Time frame: Immediately post intervention.
Blood test of the level of Blood lactate
Blood lactate
Time frame: 15 minutes after the end of intervention.
Blood test of the level of Blood lactate
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 16 Aug 2023.
- Individual participant dataSharing planned: No
Related trials for Athletes
Enrolling by invitation
Beetroot Juice and Neuromuscular Performance in Female Basketball Players
Nitrate, Placebo - Control
Not yet recruiting
Development, Implementation, and Evaluation of the HADAS Program for the Prevention of Eating Disorders in Adolescent Female Athletes, Coaches, and Families.
Eating Disorders, Body Image Dissatisfaction
Not yet recruiting
Core Strength Training, Anthropometry, and Postural Control in Youth Optimist Sailors
Postural Control, Athletic Performance
Recruiting
Neurocognitive Enrichment During Functional Performance Testing in Chronic Ankle Instability
Chronic Ankle Instability, CAI
Recruiting
Enovis High Ankle Sprain Brace Testing
Athletes in Cutting Sports
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Alia Alghwiri, PhD study director
University of Jordan
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Resistance exercise in people with Athletes, run by University of Jordan at 1 site in Jordan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 16 Aug 2023. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Jordan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Growth Hormone (time frame: Before intervention.). The study lists 6 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 16 Aug 2023.