Total Knee ArthroplastyNCT05961085
Incidence of Adductor Canal Catheter Dislodgment
An observational study of Total Knee Arthroplasty, run by Sunnybrook Health Sciences Centre at 1 site in Canada.
Trial summary
The goal of this observational study is to determine the incidence of dislodgement for adductor canal catheters after total knee arthroplasty on post-operative day 1. We will also attempt to identify factors associated with secondary catheter failure. Read more about this study
- Who is it for?
- Ages 50 years and older
- Conditions the study is for
- Total Knee Arthroplasty
- What is being tested?
- Adductor Canal Catheter
- Type of treatment
- Surgery or procedure
- How many people
- 100 participants
- Where
- 1 siteCanada
- Study dates
- 10 Jul 2023to Dec 2025
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 50 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: All patients referred to Sunnybrook Health Sciences Centre scheduled for primary total knee arthroplasty
Who may be able to join
- Patients scheduled for Total Knee Arthroplasty
- Older than 50 years
Who cannot join
- Body Mass Index greater than 40
- Chronic opioid consumption (greater than 30mg oral morphine equivalent daily)
- Contraindication to Adductor Canal Catheter
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Positioning of Continuous Adductor Canal Catheters After Total Knee Arthroplasty
The goal of this observational study is to determine the incidence of dislodgement for adductor canal catheters after total knee arthroplasty on post-operative day 1. We will also attempt to identify factors associated with secondary catheter failure.
Read the detailed description
Total knee arthroplasty (TKA) is a common procedure for indications including osteoarthritis and malignancy involving the knee, with over 55,285 knee replacements performed between 2020-2021 in Canada. Ultrasound guided continuous adductor canal block (cACB) is the standard of care for postoperative analgesia for this procedure. The catheter is not always as effective at providing analgesia as would be expected - which could be due to displacement of the catheter. This displacement is most likely to occur peri-operatively or during physiotherapy post-operatively and as such, post-operative assessments can provide useful insight into causes of secondary failure. This prospective observational study aims to estimate the cACB dislodgment on POD 1 rate at a high volume, tertiary care referral centre, and identify factors associated with dislodgement and clinical sequelae. As this is an observational/QI study of the current standard of care at Sunnybrook Health Sciences Centre, anesthesiologists are free to use the cross sectional versus parallel insertion of the cACB per their discretion.
- Conditions
- Total Knee Arthroplasty
- Being tested
- Adductor Canal Catheter
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Adductor Canal CatheterProcedure or surgery
Ultrasound guided Adductor Canal Catheter for total knee arthroplasty analgesia
| Study group | Role | What they receive |
|---|---|---|
| Adductor Canal Catheter | Pre-operative adductor canal catheter placement Receives: Procedure: Adductor Canal Catheter |
What is being measured
The primary outcome is the main question the study is designed to answer.
Adductor Canal Catheter tip in correct position on postoperative day 1
Ultrasound confirmation of injectate spread adjacent to the femoral artery on postoperative day 1 (08h00)
Measured: Postoperative day 1 (08:00AM)
Secondary outcomes (4)
Adductor Canal Catheter tip in correct position after insertion
Ultrasound confirmation of injectate spread adjacent to the femoral artery before surgery
Measured: Preoperative
Sensory block
Loss of sensation in the saphenous nerve distribution on postoperative day 1 (08h00)
Measured: Postoperative day 1 (08:00AM)
Postoperative opioid consumption (08h00)
Cumulative opioid consumption after total knee arthroplasty to postoperative day 1 (08h00)
Measured: Postoperative day 1 (08:00AM)
Numeric Rating Scale for Pain (NRS) at rest on postoperative day 1 (08h00)
Maximum pain score on 0-10 Likert Scale
Measured: Postoperative day 1 (08:00AM)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted27 Jul 2023
- Study start10 Jul 2023
- Primary completionDec 2025 (estimated)
- Study completionDec 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Total Knee ArthroplastyStudies of the same condition, open and under way.
- More trials run by Sunnybrook Health Sciences CentreThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 100 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Sunnybrook Health Sciences Centre
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05961085
- Sponsor's protocol ID
- 5845
- Status last verified
- Sep 2025
- First submitted
- 11 Jul 2023
- Last updated
- 12 Sep 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: De-identified data will be available upon request
Study at a glance
From the registry record, last updated by the sponsor on 12 Sep 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Positioning of Continuous Adductor Canal Catheters After Total Knee Arthroplasty
- ClinicalTrials.gov ID
- NCT05961085
- Acronym / sponsor ID
- 5845
- Conditions
- Total Knee Arthroplasty
- Study type
- Observational
- Recruitment status
- Active, not recruiting
- Enrolment
- 100 participants (estimated)
- Lead sponsor
- Sunnybrook Health Sciences CentreUniversity, hospital or other
- Study start
- 10 Jul 2023 (actual)
- Primary completion
- Dec 2025 (estimated)
- Study completion
- Dec 2025 (estimated)
- First posted
- 27 Jul 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this observational study is to determine the incidence of dislodgement for adductor canal catheters after total knee arthroplasty on post-operative day 1. We will also attempt to identify factors associated with secondary catheter failure.
Detailed description
Total knee arthroplasty (TKA) is a common procedure for indications including osteoarthritis and malignancy involving the knee, with over 55,285 knee replacements performed between 2020-2021 in Canada. Ultrasound guided continuous adductor canal block (cACB) is the standard of care for postoperative analgesia for this procedure. The catheter is not always as effective at providing analgesia as would be expected - which could be due to displacement of the catheter. This displacement is most likely to occur peri-operatively or during physiotherapy post-operatively and as such, post-operative assessments can provide useful insight into causes of secondary failure. This prospective observational study aims to estimate the cACB dislodgment on POD 1 rate at a high volume, tertiary care referral centre, and identify factors associated with dislodgement and clinical sequelae. As this is an observational/QI study of the current standard of care at Sunnybrook Health Sciences Centre, anesthesiologists are free to use the cross sectional versus parallel insertion of the cACB per their discretion.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Adductor Canal Catheter | – | Procedure: Adductor Canal CatheterPre-operative adductor canal catheter placement |
Who may qualify
- Ages
- 50 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- All patients referred to Sunnybrook Health Sciences Centre scheduled for primary total knee arthroplasty
Key inclusion criteria (2 listed)
- Patients scheduled for Total Knee Arthroplasty
- Older than 50 years
Key exclusion criteria (3 listed)
- Body Mass Index greater than 40
- Chronic opioid consumption (greater than 30mg oral morphine equivalent daily)
- Contraindication to Adductor Canal Catheter
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Adductor Canal CatheterUltrasound guided Adductor Canal Catheter for total knee arthroplasty analgesia | Procedure or surgery | Adductor Canal Catheter |
Primary outcome
Adductor Canal Catheter tip in correct position on postoperative day 1
Time frame: Postoperative day 1 (08:00AM)
Ultrasound confirmation of injectate spread adjacent to the femoral artery on postoperative day 1 (08h00)
4 secondary outcomes
Adductor Canal Catheter tip in correct position after insertion
Time frame: Preoperative
Sensory block
Time frame: Postoperative day 1 (08:00AM)
Postoperative opioid consumption (08h00)
Time frame: Postoperative day 1 (08:00AM)
Numeric Rating Scale for Pain (NRS) at rest on postoperative day 1 (08h00)
Time frame: Postoperative day 1 (08:00AM)
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 12 Sep 2025.
- Individual participant dataSharing planned: Yes. De-identified data will be available upon request
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Total Knee Arthroplasty, run by Sunnybrook Health Sciences Centre at 1 site in Canada.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 12 Sep 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Canada. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Adductor Canal Catheter tip in correct position on postoperative day 1 (time frame: Postoperative day 1 (08:00AM)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 12 Sep 2025.