Patellofemoral Pain SyndromeNCT05971966
Effects of Virtual Reality Rehabilitation and Muscle Energy Technique in Patients With Patellofemoral Pain Syndrome.
A study testing Virtual Reality technique and Muscle energy technique in people with Patellofemoral Pain Syndrome and Knee Pain Chronic, run by Riphah International University at 1 site in Pakistan.
Trial summary
The aim of this randomized controlled trial is to determine the effects of Virtual reality rehabilitation and muscle energy techniques in patients with patellofemoral pain syndrome for reducing pain, enhancing knee range of motion and improve functional activities. Read more about this study
- Who is it for?
- Ages 18 to 40 years
- Conditions the study is for
- Patellofemoral Pain Syndrome, Knee Pain Chronic
- What is being tested?
- Virtual Reality technique and Muscle energy technique
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 32 participants
- Where
- 1 sitePakistan
- Study dates
- 30 Aug 2023to 28 Apr 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 40 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Age group 18-40
- Both males and females
- Retropatellar or anterior knee pain for atleast past 3 months
- Having knee pain in atleast 2 activities among stair ascent and descent,squatting over 90 degrees, running,jumping,kneeling and prolong sitting with knees flexed.
- Experience pain in one of the following knee tests; a) pain on patellar grinding test, b) pain on apprehension test, c) pain during resisted extension of the knee during 90 degree flexion
Who cannot join
- Cervical radiculopathy
- Neurological disorder
- Pregnancy
- Rheumatoid arthritis
- Hip or ankle injuries
- Patellar instabilities
Show all 13Show fewer
- Meniscal or ligament tear
- Who have visual or auditory problems
- With cognitive issues
- Previous surgery related to lower limbs/ radiculopathy
- having received knee injections of corticosteroids or hyaluronic acid
- knee osteoarthritis
- drug use that affects the balance during the past 72 h.
Trial locations and contacts
1 site in 1 country.
Pakistan1 site, 1 recruiting
- Recruiting
Dr.z pain & brain physiotherapy center
Islamabad, Punjab Province
KINZA ANWAR, MS-OMPT, +92-3239735427, kinza.anwar@riphah.edu.pk
Nayab Mehmood, MS-OMPT*
About this study
Official title: Effect of Virtual Reality Rehabilitation and Muscle Energy Technique in Patients With Patellofemoral Pain Syndrome.
The aim of this randomized controlled trial is to determine the effects of Virtual reality rehabilitation and muscle energy techniques in patients with patellofemoral pain syndrome for reducing pain, enhancing knee range of motion and improve functional activities.
Read the detailed description
Muscle energy technique is defined as a manual treatment in which patient produces a contraction in a precisely controlled position and direction against the counterforce applied by a manual therapist. Applications of MET to stretch and increase myofascial tissue extensibility seem to affect viscoelastic and plastic tissue property.
Virtual reality generates a virtual world in three dimensional space through a computer simulation that stimulates user senses, such as sight and hearing, making users feel as if they are immersed in it. VRBR is effective in improving knee pain, ROM, strength and functions. immersive VR is more appropriate for pain reduction, improving range of motion and functional activities. It distracts the patient and allows to perform active and rehabilitation exercises to reduce cognitive attention in pain and avoidance behavior.
- Conditions
- Patellofemoral Pain Syndrome, Knee Pain Chronic
- Being tested
- Virtual Reality technique, Muscle energy technique
- Keywords
- muscle energy technique, virtual reality technique, knee pain
- Medical subject headings
- Patellofemoral Pain Syndrome
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Virtual Reality techniqueOther
They would be receiving treatment as follow:
Specific exercises by using virtual reality with conventional treatment. The VR game included holopoint,hot squat and portal stories that will target the hamstring, quadriceps and gluteas muscles.Frequency: 3 times/week for 4 weeks Intensity: moderate intensity (pain free) Time: 20 mins Type: virtual reality gaming exercises Conventional PT including patellar mobilization+ ultrasound on anterior knee in supine lying + stretching of ITB . Frequency: 10 reps with 5 sec hold for 3 times/week for 4 weeks Intensity: moderate-high intensity (depending on pain tolerance) Time: 10 mins
Muscle energy techniqueOther
They would be receiving treatment as follow:
Muscle energy technique of quadriceps and hamstring muscles. Frequency: 3 times/week for 4 weeks Intensity: moderate intensity (pain free) Time: 20 mins Type: Muscle energy technique to improve range of motion.
Conventional PT including patellar mobilization + ultrasound on anterior knee in supine lying + stretching of ITB. Frequency: 10 reps with 5 sec hold for 3 times/week for 2 weeks Intensity: moderate-high intensity (depending on pain tolerance) Time: 10 mins
| Study group | Role | What they receive |
|---|---|---|
| Virtual Reality technique | Active comparator | Virtual reality technique+ Conventional PT Receives: Other: Virtual Reality technique |
| Muscle energy technique | Experimental | Muscle energy technique + Conventional PT Receives: Other: Muscle energy technique |
What is being measured
The primary outcome is the main question the study is designed to answer.
Kujala questionnaire
It is a self administered questionnaire for patients with PFPS that consists of 13 questions that relate to specified activities, pain severity, and clinical symptoms. The scores range from a maximum of 100 to a minimum of 0, with lower scores indicating greater pain and disability.
Measured: 4 weeks
Secondary outcomes (2)
Visual analogue scale (VAS)
VAS is a qualitative pain measurement tool that assigns integer numbers between zero and 10 to different pain levels, where zero means no pain and 10 means excruciating pain. VAS is a reliable scale to measure knee pain
Measured: 4 weeks
Goniometer
It is an instrument that measures the available range of motion at a joint.
Measured: 4 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted2 Aug 2023
- Study start30 Aug 2023
- Primary completion28 Mar 2024 (estimated)
- Study completion28 Apr 2024 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Patellofemoral Pain SyndromeStudies of the same condition, open and under way.
- More trials run by Riphah International UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 32 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Kinza Anwar, MS-OMPT, Principal investigator, Riphah International University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05971966
- Sponsor's protocol ID
- REC/01652 Nayab Mehmood
- Status last verified
- Aug 2023
- First submitted
- 25 Jul 2023
- Last updated
- 5 Sep 2023
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 5 Sep 2023. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Virtual Reality Rehabilitation and Muscle Energy Technique in Patients With Patellofemoral Pain Syndrome.
- ClinicalTrials.gov ID
- NCT05971966
- Acronym / sponsor ID
- REC/01652 Nayab Mehmood
- Conditions
- Patellofemoral Pain Syndrome, Knee Pain Chronic
- Keywords
- muscle energy technique, virtual reality technique, knee pain
- Study type
- Interventional
- Recruitment status
- Unknown status
- Enrolment
- 32 participants (estimated)
- Lead sponsor
- Riphah International UniversityUniversity, hospital or other
- Study start
- 30 Aug 2023 (actual)
- Primary completion
- 28 Mar 2024 (estimated)
- Study completion
- 28 Apr 2024 (estimated)
- First posted
- 2 Aug 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this randomized controlled trial is to determine the effects of Virtual reality rehabilitation and muscle energy techniques in patients with patellofemoral pain syndrome for reducing pain, enhancing knee range of motion and improve functional activities.
Detailed description
Muscle energy technique is defined as a manual treatment in which patient produces a contraction in a precisely controlled position and direction against the counterforce applied by a manual therapist. Applications of MET to stretch and increase myofascial tissue extensibility seem to affect viscoelastic and plastic tissue property.
Virtual reality generates a virtual world in three dimensional space through a computer simulation that stimulates user senses, such as sight and hearing, making users feel as if they are immersed in it. VRBR is effective in improving knee pain, ROM, strength and functions. immersive VR is more appropriate for pain reduction, improving range of motion and functional activities. It distracts the patient and allows to perform active and rehabilitation exercises to reduce cognitive attention in pain and avoidance behavior.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Virtual Reality technique | Active comparator | Other: Virtual Reality techniqueVirtual reality technique+ Conventional PT |
| Muscle energy technique | Experimental | Other: Muscle energy techniqueMuscle energy technique + Conventional PT |
Who may qualify
- Ages
- 18 to 40 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- Age group 18-40
- Both males and females
- Retropatellar or anterior knee pain for atleast past 3 months
- Having knee pain in atleast 2 activities among stair ascent and descent,squatting over 90 degrees, running,jumping,kneeling and prolong sitting with knees flexed.
- Experience pain in one of the following knee tests; a) pain on patellar grinding test, b) pain on apprehension test, c) pain during resisted extension of the knee during 90 degree flexion
Key exclusion criteria (13 listed)
- Cervical radiculopathy
- Neurological disorder
- Pregnancy
- Rheumatoid arthritis
- Hip or ankle injuries
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Virtual Reality techniqueThey would be receiving treatment as follow: Specific exercises by using virtual reality with conventional treatment. The VR game included holopoint,hot squat and portal stories that will target the hamstring, quadriceps and gluteas muscles.Frequency: 3 times/week for 4 weeks Intensity: moderate intensity (pain free) Time: 20 mins Type: virtual reality gaming exercises Conventional PT including patellar mobilization+ ultrasound on anterior knee in supine lying + stretching of ITB . Frequency: 10 reps with 5 sec hold for 3 times/week for 4 weeks Intensity: moderate-high intensity (depending on pain tolerance) Time: 10 mins | Other | Virtual Reality technique |
| Muscle energy techniqueThey would be receiving treatment as follow: Muscle energy technique of quadriceps and hamstring muscles. Frequency: 3 times/week for 4 weeks Intensity: moderate intensity (pain free) Time: 20 mins Type: Muscle energy technique to improve range of motion. Conventional PT including patellar mobilization + ultrasound on anterior knee in supine lying + stretching of ITB. Frequency: 10 reps with 5 sec hold for 3 times/week for 2 weeks Intensity: moderate-high intensity (depending on pain tolerance) Time: 10 mins | Other | Muscle energy technique |
Primary outcome
Kujala questionnaire
Time frame: 4 weeks
It is a self administered questionnaire for patients with PFPS that consists of 13 questions that relate to specified activities, pain severity, and clinical symptoms. The scores range from a maximum of 100 to a minimum of 0, with lower scores indicating greater pain and disability.
2 secondary outcomes
Visual analogue scale (VAS)
Time frame: 4 weeks
Goniometer
Time frame: 4 weeks
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 Sep 2023.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Kinza Anwar, MS-OMPT principal investigator
Riphah International University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Virtual Reality technique and Muscle energy technique in people with Patellofemoral Pain Syndrome and Knee Pain Chronic, run by Riphah International University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 13 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 5 Sep 2023. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
Contact Kinza Anwar, MS-OMPT (+92-3239735427, kinza.anwar@riphah.edu.pk), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Kujala questionnaire (time frame: 4 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Sep 2023.