Postprandial LipemiaNCT05977244
Exploring the Effects of Varying Fat:Carbohydrate Diet Permutations on Gastric Emptying and Metabolic Status Using Human Postprandial Model
A study testing FIJA, F1JB and F2JA in people with Postprandial Lipemia and Postprandial Glycemia, run by Malaysia Palm Oil Board at 3 sites in Malaysia.
Trial summary
The aim of this clinical trial is to investigate the effects of the meals moderated by fat and carbohydrate (CHO) quality along with varying macronutrient distribution (CHO: fat) on gut physiology and metabolic outcomes using the human postprandial model with healthy subjects. Read more about this study
- Who is it for?
- Ages 21 to 40 yearsHealthy volunteers can take part
- Conditions the study is for
- Postprandial Lipemia, Postprandial Glycemia, Gastric Emptying
- What is being tested?
- FIJA, F1JB and F2JA
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 12 participants
- Where
- 3 sitesMalaysia
- Study dates
- 21 May 2022to 24 Dec 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 21 to 40 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Healthy subjects, (n=12-14) without history of chronic disease(s) with body mass index (BMI) between 18.5-25.0 kg/m2 and normal fasting blood glucose status [<5.4 mmol/L] will be enrolled into the study.
Who cannot join
- Using pharmacotherapy that interferes with lipid and glucose metabolism or gastrointestinal transit (constipating drugs) or on oral contraceptives (women).
- Underweight body mass index (BMI): < 18.5 kg/m2
- With medical history of cardiovascular disease (CVD), Diabetes Mellitus, dyslipidemia and other chronic diseases,
- acute or chronic gastrointestinal illness
- If vulnerable to claustrophobia or anxiety
- Regular alcohol usage
- On low-calorie diets
- Smoking
Trial locations and contacts
3 sites in 1 country.
Malaysia3 sites
Malaysian Palm Oil Board
Kajang, Selangor, 43000
Department of Medicine, Faculty of Medicine, Hospital Cancelor Tuanku Mukhriz, Universiti Kebangsaan Malaysia
Kuala Lumpur, Kuala Lumpur, 56000
School of Biosciences, Faculty of Health and Medical Sciences, Taylor's University
Subang Jaya, Selangor, 47500
About this study
The aim of this clinical trial is to investigate the effects of the meals moderated by fat and carbohydrate (CHO) quality along with varying macronutrient distribution (CHO: fat) on gut physiology and metabolic outcomes using the human postprandial model with healthy subjects.
The main question[s] it aims to answer are:
- How does meal composition with different polyunsaturated/saturated (P/S) ratio, glycemic index and macronutrient quantity affect lipemia and glycemia?
- How does meal composition with different P/S ratio, Glycemic index and macronutrient quantity affect gastric emptying?
Read the detailed description
The study's objectives will be tested via a crossover study with 18 diet rotations separated by minimum one week washout period. All recruited subjects will be assigned into, 9 HGI and 9 LGI diet rotations. The study design will be a cross-over trial with the same subjects undergoing all arms of the diet rotations. The subjects will be blinded to the test fats used for each rotation. Body weight measurements will be recorded before each postprandial challenge to minimise weight fluctuations between the test rotations.
Study procedures
- Oral glucose tolerance test (OGTT) Sessions Prior and end of the test meal rotations, subjects will undergo oral glucose tolerance test (OGTT) with a glucose reference drink at 2 random sessions without MRI investigation at Taylor's University or Hospital Cancelor Tuanku Muhriz (HCTM), to get an average value for the plasma glucose and insulin standards for each subject. The glucose reference drink composition will be 50g of anhydrous glucose mixed with 250mL of room temperature water. Blood samples will be collected sequentially at 0, 15, 30, 60, 90,120 and 180 minutes.
- Test meal sessions
During each postprandial test meal rotations, subjects will consume test meals followed by MRI scans at the MRI center at Hospital Cancelor Tuanku Muhriz(HCTM). For scheduled session, Subjects will be advised to refrain from strenuous physical activity, high calorie or fast-food, supplements and coffee intake for 24 hours preceding each postprandial event. Subjects will be at the clinical center at 7:30 and 8:30a.m, following a 12-hour overnight fast. Upon arrival at the centre, subjects will rest for 10min, followed by body weight, blood pressure and self-monitoring of blood glucose (SBMG) measurements. Subsequently, blood samples will be drawn for metabolic investigations as per study objectives. Sequential postprandial MRI scans before and after test meal intake at 0(fasting), 15, 30, 60, 90, 120, 180, 240 and 300 minutes.
- Being tested
- FIJA, F1JB, F2JA, F2JB, F3JA
- Keywords
- meal composition, P/S ratio, macronutrient distribution, glycemic index, glycemia, lipemia, gut hormones, gastric emptying
- Medical subject headings
- Hyperlipidemias
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
FIJAOther
A 5-hour postprandial feeding intervention with 1-weeks washout in between. Blood samples will be collected at 0 hour (baseline) and up to 5 hours after consumption of test meal.
F1JBOther
A 5-hour postprandial feeding intervention with 1-weeks washout in between. Blood samples will be collected at 0 hour (baseline) and up to 5 hours after consumption of test meal.
F2JAOther
A 5-hour postprandial feeding intervention with 1-weeks washout in between. Blood samples will be collected at 0 hour (baseline) and up to 5 hours after consumption of test meal.
F2JBOther
A 5-hour postprandial feeding intervention with 1-weeks washout in between. MRI scan and blood samples will be collected at 0 hour (baseline) and up to 5 hours after consumption of test meal.
F3JAOther
A 5-hour postprandial feeding intervention with 1-weeks washout in between. MRI scan and blood samples will be collected at 0 hour (baseline) and up to 5 hours after consumption of test meal.
F3JBOther
A 5-hour postprandial feeding intervention with 1-weeks washout in between. MRI scan and blood samples will be collected at 0 hour (baseline) and up to 5 hours after the consumption of test meal.
F4JAOther
A 5-hour postprandial feeding intervention with 1-weeks washout in between. MRI scan and blood samples will be collected at 0 hour (baseline) and up to 5 hours after consumption of test meal.
F4JBOther
A 5-hour postprandial feeding intervention with 1-weeks washout in between. MRI scan and blood samples will be collected at 0 hour (baseline) and up to 5 hours after consumption of test meal.
F1PAOther
A 5-hour postprandial feeding intervention with 1-weeks washout in between. MRI scan and blood samples will be collected at 0 hour (baseline) and up to 5 hours after consumption of test meal.
F1PBOther
A 5-hour postprandial feeding intervention with 1-weeks washout in between. MRI scan and blood samples will be collected at 0 hour (baseline) and up to 5 hours after consumption of test meal.
F2PAOther
A 5-hour postprandial feeding intervention with 1-weeks washout in between. MRI scan and blood samples will be collected at 0 hour (baseline) and up to 5 hours after consumption of test meal.
F2PBOther
A 5-hour postprandial feeding intervention with 1-weeks washout in between. MRI scan and blood samples will be collected at 0 hour (baseline) and up to 5 hours after consumption of test meal.
F3PAOther
A 5-hour postprandial feeding intervention with 1-weeks washout in between. MRI scan and blood samples will be collected at 0 hour (baseline) and up to 5 hours after consumption of test meal.
F3PBOther
A 5-hour postprandial feeding intervention with 1-weeks washout in between. MRI scan and blood samples will be collected at 0 hour (baseline) and up to 5 hours after consumption of test meal.
F4PAOther
A 5-hour postprandial feeding intervention with 1-weeks washout in between. MRI scan and blood samples will be collected at 0 hour (baseline) and up to 5 hours after consumption of test meal.
F4PBOther
A 5-hour postprandial feeding intervention with 1-weeks washout in between. MRI scan and blood samples will be collected at 0 hour (baseline) and up to 5 hours after consumption of test meal.
HGI PLAIN RICEOther
A 5-hour postprandial feeding intervention with 1-weeks washout in between. MRI scan and blood samples will be collected at 0 hour (baseline) and up to 5 hours after consumption of test meal.
LGI PLAIN RICEOther
A 5-hour postprandial feeding intervention with 1-weeks washout in between. MRI scan and blood samples will be collected at 0 hour (baseline) and up to 5 hours after consumption of test meal.
| Study group | Role | What they receive |
|---|---|---|
| DIET FIJA | Experimental | 1 portion of HGI (high glycemic index) fried rice, fried with oil A served together with 250 milliliter of plain water. Receives: Other: FIJA |
| DIET F1JB | Experimental | 1 portion of HGI (high glycemic index) fried rice, fried with oil B served with 250 milliliter of plain water. Receives: Other: F1JB |
| DIET F2JA | Experimental | 1 portion of HGI (high glycemic index) fried rice, fried with oil A served with 250 milliliter of plain water. Receives: Other: F2JA |
| DIET F2JB | Experimental | 1 portion of HGI (high glycemic index) fried rice, fried with oil B served with 250 milliliter of plain water. Receives: Other: F2JB |
| DIET F3JA | Experimental | 1 portion of HGI (high glycemic index) fried rice, fried with oil A served with 250 milliliter of plain water. Receives: Other: F3JA |
| DIET F3JB | Experimental | 1 portion of HGI (high glycemic index) fried rice, fried with oil B served with 250 milliliter of plain water. Receives: Other: F3JB |
| DIET F4JA | Experimental | 1 portion of HGI (high glycemic index) fried rice, fried with oil A served with 250 milliliter of plain water. Receives: Other: F4JA |
| DIET F4JB | Experimental | 1 portion of HGI (high glycemic index) fried rice, fried with oil B served with 250 milliliter of plain water. Receives: Other: F4JB |
| DIET F1PA | Experimental | 1 portion of LGI (low glycemic index) fried rice, fried with oil A served with 250 milliliter of plain water. Receives: Other: F1PA |
| DIET F1PB | Experimental | 1 portion of LGI (low glycemic index) fried rice, fried with oil B served with 250 milliliter of plain water. Receives: Other: F1PB |
| DIET F2PA | Experimental | 1 portion of LGI (low glycemic index) fried rice, fried with oil A served with 250 milliliter of plain water. Receives: Other: F2PA |
| DIET F2PB | Experimental | 1 portion of LGI (low glycemic index) fried rice, fried with oil B served with 250 milliliter of plain water. Receives: Other: F2PB |
| DIET F3PA | Experimental | 1 portion of LGI (low glycemic index) fried rice, fried with oil A served with 250 milliliter of plain water. Receives: Other: F3PA |
| DIET F3PB | Experimental | 1 portion of LGI (low glycemic index) fried rice, fried with oil B served with 250 milliliter of plain water. Receives: Other: F3PB |
| DIET F4PA | Experimental | 1 portion of LGI (low glycemic index) fried rice, fried with oil A served with 250 milliliter of plain water. Receives: Other: F4PA |
| DIET F4PB | Experimental | 1 portion of LGI (low glycemic index) fried rice, fried with oil B served together with 250 milliliter of plain water. Receives: Other: F4PB |
| HGI PLAIN RICE | Placebo comparator | 1 portion of HGI (low glycemic index) plain rice served with 250 milliliters of plain water. Receives: Other: HGI PLAIN RICE |
| LGI PLAIN RICE | Placebo comparator | 1 portion of HGI (low glycemic index) plain rice served with 250 milliliters of plain water. Receives: Other: LGI PLAIN RICE |
What is being measured
The primary outcome is the main question the study is designed to answer.
Lipemia
To determine the postprandial changes in triacylglyceride (TAG)
Measured: 0, 15, 30, 60, 90, 120, 180, 240, 300minutes after ingestion of test meals
Glycemia
To determine the postprandial changes of glucose
Measured: 0, 15, 30, 60, 90, 120, 180, 240, 300minutes after ingestion of test meals
Secondary outcomes (2)
Gastric emptying
To determine the postprandial changes in half emptying time
Measured: 0, 15, 30, 60, 90, 120, 180, 240, 300minutes after ingestion of test meals
Gut hormone
To determine the postprandial changes of glucose-dependent insulinotropic polypeptide (GIP)
Measured: 0, 15, 30, 60, 90, 120, 180, 240, 300minutes after ingestion of test meals
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted4 Aug 2023
- Study start21 May 2022
- Primary completion24 Dec 2024
- Study completion24 Dec 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Postprandial LipemiaStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Non-randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Enrolment
- 12 participants (actual)
Sponsor and investigators
- Lead sponsor
- Malaysia Palm Oil Board
- Sponsor type
- Other government
- Collaborators
- Taylor's University, National University of Malaysia
- Responsible party
- Sponsor
- Investigators
- Gowri Nagapan, Principal investigator, Malaysia Palm Oil BoardTilakavati Dr Karupaiah, PhD, Study chair, School of Biosciences, Faculty of Health and Medical Sciences, Taylor's University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05977244
- Sponsor's protocol ID
- PD233/18
- Status last verified
- May 2026
- First submitted
- 17 Jul 2023
- Last updated
- 26 May 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 26 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Exploring the Effects of Varying Fat:Carbohydrate Diet Permutations on Gastric Emptying and Metabolic Status Using Human Postprandial Model
- ClinicalTrials.gov ID
- NCT05977244
- Acronym / sponsor ID
- PD233/18
- Keywords
- meal composition, P/S ratio, macronutrient distribution, glycemic index, glycemia, lipemia, gut hormones, gastric emptying
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 12 participants (actual)
- Lead sponsor
- Malaysia Palm Oil BoardOther government
- Collaborators
- Taylor's University, National University of Malaysia
- Study start
- 21 May 2022 (actual)
- Primary completion
- 24 Dec 2024 (actual)
- Study completion
- 24 Dec 2024 (actual)
- First posted
- 4 Aug 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this clinical trial is to investigate the effects of the meals moderated by fat and carbohydrate (CHO) quality along with varying macronutrient distribution (CHO: fat) on gut physiology and metabolic outcomes using the human postprandial model with healthy subjects.
The main question[s] it aims to answer are:
- How does meal composition with different polyunsaturated/saturated (P/S) ratio, glycemic index and macronutrient quantity affect lipemia and glycemia?
- How does meal composition with different P/S ratio, Glycemic index and macronutrient quantity affect gastric emptying?
Detailed description
The study's objectives will be tested via a crossover study with 18 diet rotations separated by minimum one week washout period. All recruited subjects will be assigned into, 9 HGI and 9 LGI diet rotations. The study design will be a cross-over trial with the same subjects undergoing all arms of the diet rotations. The subjects will be blinded to the test fats used for each rotation. Body weight measurements will be recorded before each postprandial challenge to minimise weight fluctuations between the test rotations.
Study procedures
- Oral glucose tolerance test (OGTT) Sessions Prior and end of the test meal rotations, subjects will undergo oral glucose tolerance test (OGTT) with a glucose reference drink at 2 random sessions without MRI investigation at Taylor's University or Hospital Cancelor Tuanku Muhriz (HCTM), to get an average value for the plasma glucose and insulin standards for each subject. The glucose reference drink composition will be 50g of anhydrous glucose mixed with 250mL of room temperature water. Blood samples will be collected sequentially at 0, 15, 30, 60, 90,120 and 180 minutes.
- Test meal sessions
During each postprandial test meal rotations, subjects will consume test meals followed by MRI scans at the MRI center at Hospital Cancelor Tuanku Muhriz(HCTM). For scheduled session, Subjects will be advised to refrain from strenuous physical activity, high calorie or fast-food, supplements and coffee intake for 24 hours preceding each postprandial event. Subjects will be at the clinical center at 7:30 and 8:30a.m, following a 12-hour overnight fast. Upon arrival at the centre, subjects will rest for 10min, followed by body weight, blood pressure and self-monitoring of blood glucose (SBMG) measurements. Subsequently, blood samples will be drawn for metabolic investigations as per study objectives. Sequential postprandial MRI scans before and after test meal intake at 0(fasting), 15, 30, 60, 90, 120, 180, 240 and 300 minutes.
Study design
- Primary purpose
- Prevention
- Allocation
- Non-randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Number of arms
- 18
| Arm | Type | Receives |
|---|---|---|
| DIET FIJA | Experimental | Other: FIJA1 portion of HGI (high glycemic index) fried rice, fried with oil A served together with 250 milliliter of plain water. |
| DIET F1JB | Experimental | Other: F1JB1 portion of HGI (high glycemic index) fried rice, fried with oil B served with 250 milliliter of plain water. |
| DIET F2JA | Experimental | Other: F2JA1 portion of HGI (high glycemic index) fried rice, fried with oil A served with 250 milliliter of plain water. |
| DIET F2JB | Experimental | Other: F2JB1 portion of HGI (high glycemic index) fried rice, fried with oil B served with 250 milliliter of plain water. |
| DIET F3JA | Experimental | Other: F3JA1 portion of HGI (high glycemic index) fried rice, fried with oil A served with 250 milliliter of plain water. |
| DIET F3JB | Experimental | Other: F3JB1 portion of HGI (high glycemic index) fried rice, fried with oil B served with 250 milliliter of plain water. |
| DIET F4JA | Experimental | Other: F4JA1 portion of HGI (high glycemic index) fried rice, fried with oil A served with 250 milliliter of plain water. |
| DIET F4JB | Experimental | Other: F4JB1 portion of HGI (high glycemic index) fried rice, fried with oil B served with 250 milliliter of plain water. |
| DIET F1PA | Experimental | Other: F1PA1 portion of LGI (low glycemic index) fried rice, fried with oil A served with 250 milliliter of plain water. |
| DIET F1PB | Experimental | Other: F1PB1 portion of LGI (low glycemic index) fried rice, fried with oil B served with 250 milliliter of plain water. |
| DIET F2PA | Experimental | Other: F2PA1 portion of LGI (low glycemic index) fried rice, fried with oil A served with 250 milliliter of plain water. |
| DIET F2PB | Experimental | Other: F2PB1 portion of LGI (low glycemic index) fried rice, fried with oil B served with 250 milliliter of plain water. |
| DIET F3PA | Experimental | Other: F3PA1 portion of LGI (low glycemic index) fried rice, fried with oil A served with 250 milliliter of plain water. |
| DIET F3PB | Experimental | Other: F3PB1 portion of LGI (low glycemic index) fried rice, fried with oil B served with 250 milliliter of plain water. |
| DIET F4PA | Experimental | Other: F4PA1 portion of LGI (low glycemic index) fried rice, fried with oil A served with 250 milliliter of plain water. |
| DIET F4PB | Experimental | Other: F4PB1 portion of LGI (low glycemic index) fried rice, fried with oil B served together with 250 milliliter of plain water. |
| HGI PLAIN RICE | Placebo comparator | Other: HGI PLAIN RICE1 portion of HGI (low glycemic index) plain rice served with 250 milliliters of plain water. |
| LGI PLAIN RICE | Placebo comparator | Other: LGI PLAIN RICE1 portion of HGI (low glycemic index) plain rice served with 250 milliliters of plain water. |
Who may qualify
- Ages
- 21 to 40 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (1 listed)
- Healthy subjects, (n=12-14) without history of chronic disease(s) with body mass index (BMI) between 18.5-25.0 kg/m2 and normal fasting blood glucose status [<5.4 mmol/L] will be enrolled into the study.
Key exclusion criteria (8 listed)
- Using pharmacotherapy that interferes with lipid and glucose metabolism or gastrointestinal transit (constipating drugs) or on oral contraceptives (women).
- Underweight body mass index (BMI): < 18.5 kg/m2
- With medical history of cardiovascular disease (CVD), Diabetes Mellitus, dyslipidemia and other chronic diseases,
- acute or chronic gastrointestinal illness
- If vulnerable to claustrophobia or anxiety
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| FIJAA 5-hour postprandial feeding intervention with 1-weeks washout in between. Blood samples will be collected at 0 hour (baseline) and up to 5 hours after consumption of test meal. | Other | DIET FIJA |
| F1JBA 5-hour postprandial feeding intervention with 1-weeks washout in between. Blood samples will be collected at 0 hour (baseline) and up to 5 hours after consumption of test meal. | Other | DIET F1JB |
| F2JAA 5-hour postprandial feeding intervention with 1-weeks washout in between. Blood samples will be collected at 0 hour (baseline) and up to 5 hours after consumption of test meal. | Other | DIET F2JA |
| F2JBA 5-hour postprandial feeding intervention with 1-weeks washout in between. MRI scan and blood samples will be collected at 0 hour (baseline) and up to 5 hours after consumption of test meal. | Other | DIET F2JB |
| F3JAA 5-hour postprandial feeding intervention with 1-weeks washout in between. MRI scan and blood samples will be collected at 0 hour (baseline) and up to 5 hours after consumption of test meal. | Other | DIET F3JA |
| F3JBA 5-hour postprandial feeding intervention with 1-weeks washout in between. MRI scan and blood samples will be collected at 0 hour (baseline) and up to 5 hours after the consumption of test meal. | Other | DIET F3JB |
| F4JAA 5-hour postprandial feeding intervention with 1-weeks washout in between. MRI scan and blood samples will be collected at 0 hour (baseline) and up to 5 hours after consumption of test meal. | Other | DIET F4JA |
| F4JBA 5-hour postprandial feeding intervention with 1-weeks washout in between. MRI scan and blood samples will be collected at 0 hour (baseline) and up to 5 hours after consumption of test meal. | Other | DIET F4JB |
| F1PAA 5-hour postprandial feeding intervention with 1-weeks washout in between. MRI scan and blood samples will be collected at 0 hour (baseline) and up to 5 hours after consumption of test meal. | Other | DIET F1PA |
| F1PBA 5-hour postprandial feeding intervention with 1-weeks washout in between. MRI scan and blood samples will be collected at 0 hour (baseline) and up to 5 hours after consumption of test meal. | Other | DIET F1PB |
| F2PAA 5-hour postprandial feeding intervention with 1-weeks washout in between. MRI scan and blood samples will be collected at 0 hour (baseline) and up to 5 hours after consumption of test meal. | Other | DIET F2PA |
| F2PBA 5-hour postprandial feeding intervention with 1-weeks washout in between. MRI scan and blood samples will be collected at 0 hour (baseline) and up to 5 hours after consumption of test meal. | Other | DIET F2PB |
| F3PAA 5-hour postprandial feeding intervention with 1-weeks washout in between. MRI scan and blood samples will be collected at 0 hour (baseline) and up to 5 hours after consumption of test meal. | Other | DIET F3PA |
| F3PBA 5-hour postprandial feeding intervention with 1-weeks washout in between. MRI scan and blood samples will be collected at 0 hour (baseline) and up to 5 hours after consumption of test meal. | Other | DIET F3PB |
| F4PAA 5-hour postprandial feeding intervention with 1-weeks washout in between. MRI scan and blood samples will be collected at 0 hour (baseline) and up to 5 hours after consumption of test meal. | Other | DIET F4PA |
| F4PBA 5-hour postprandial feeding intervention with 1-weeks washout in between. MRI scan and blood samples will be collected at 0 hour (baseline) and up to 5 hours after consumption of test meal. | Other | DIET F4PB |
| HGI PLAIN RICEA 5-hour postprandial feeding intervention with 1-weeks washout in between. MRI scan and blood samples will be collected at 0 hour (baseline) and up to 5 hours after consumption of test meal. | Other | HGI PLAIN RICE |
| LGI PLAIN RICEA 5-hour postprandial feeding intervention with 1-weeks washout in between. MRI scan and blood samples will be collected at 0 hour (baseline) and up to 5 hours after consumption of test meal. | Other | LGI PLAIN RICE |
Primary outcome
Lipemia
Time frame: 0, 15, 30, 60, 90, 120, 180, 240, 300minutes after ingestion of test meals
To determine the postprandial changes in triacylglyceride (TAG)
Glycemia
Time frame: 0, 15, 30, 60, 90, 120, 180, 240, 300minutes after ingestion of test meals
To determine the postprandial changes of glucose
2 secondary outcomes
Gastric emptying
Time frame: 0, 15, 30, 60, 90, 120, 180, 240, 300minutes after ingestion of test meals
Gut hormone
Time frame: 0, 15, 30, 60, 90, 120, 180, 240, 300minutes after ingestion of test meals
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 26 May 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Gowri Nagapan principal investigator
Malaysia Palm Oil Board
Tilakavati Dr Karupaiah, PhD study chair
School of Biosciences, Faculty of Health and Medical Sciences, Taylor's University
3 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing FIJA, F1JB and F2JA in people with Postprandial Lipemia and Postprandial Glycemia, run by Malaysia Palm Oil Board at 3 sites in Malaysia.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 26 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 3 sites in Malaysia. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Lipemia (time frame: 0, 15, 30, 60, 90, 120, 180, 240, 300minutes after ingestion of test meals). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 26 May 2026.